Surgery neih chhunga anesthesia hman avanga thil hlauhawm tak Malignant Hyperthermia chungchang i zir dawn teh ang.

Nangmah emaw, i chhungte zinga tu emaw chu operation neih a ngai a nih chuan a hmain anesthesia pek i ni ang, a dik em? A awlsam zawngin, min muthilh tir vek a ni. Mahse mi thenkhat tan chuan he anesthesia atana hman damdawi thenkhat hian ngaihtuah phak loh khawpa na tak, nunna atana hlauhawm tak pawh a thlen thei a ni. Vawiin hian malignant hyperthermia , natna hlauhawm tak, mahse a hmaa hmuhchhuah a nih chuan enkawl theih a nih thu kan sawi dawn a ni.

Malignant Hyperthermia hi eng nge ni?

A awlsam zawngin Malignant Hyperthermia hi genetic condition a ni. Chumi awmzia chu rochun a ni tihna a ni. Hetiang natna vei hi operation an neih laiin anesthesia chi hrang hrang an hman chuan an taksa hian nasa takin a chhang let thin. Hei hi nunna atana hlauhawm emergency a ni. Mahse hetah hian a pawimawh ber chu operation neih chhunga anesthesia atana hman damdawi zawng zawngah hian hetiang hi a thleng lo. Damdawi tlemte chauh hian he thil hi a thlen thin. Chu bâkah, hriat chhuah a nih chuan enkawl thuai theih a ni. A tam zawkah chuan mi pakhat hian a taksaah he thil nena inzawm gene mutation a nei tih a hre lo. A chhan chu nun pangngaiah symptom an lantir loh vang a ni. Buaina chu chu anaesthetic damdawi bik chu taksaa a luh chauhvin a lo chhuak thin.

Tu nge hlauhawm zawk?

He hlauhawmna hi chhungkaw zinga mi pakhatin he natna hi a neih chuan a awm ber a ni.

• Chhungkaw chanchin: I chhungte hnai tak - nu, pa, unaupa, unaunu emaw, i fa emaw -in malignant hyperthermia a vei a nih chuan i hlauhawmna a sang hle. Chuvangin, operation i neih tawh chuan he chhungkaw chanchin hi anesthesiologist hnenah hrilh a pawimawh hle .
• Taksa natna thenkhat: I chhungkuaa tumahin he harsatna hi an nei lo a nih pawhin, taksa ruh natna tlemte nei te chu an hlauhawm zawk. Entir nan:
• Central core natna a ni
• Multiminicore natna a ni
• King-Denborough natna a ni
• STAC3 natna a ni

Hengte hi thil awm lo tak tak a ni a, mahse nangmah emaw, i chhungte emaw hian i nei a nih chuan i doctor hriattir a pawimawh hle.

Hetiang dinhmun hi engtiang chiahin nge a awm?

Hei hi a takah chuan thil awm dan tlangpui a ni lo. Statistics atanga a lan dan chuan he natna hi puitling operation 100,000 zinga pakhat vel ah a awm thin. Naupang tê tê zîngah chuan he zat hi a tam deuh a, chu chu zai 30,000 zînga pakhat tihna a ni. Hriat tur pawimawh tak chu damlo hmuhchhuah zinga a chanve chu kum 19 hnuai lam an ni a, mahse, scientist-te chuan hetiang thil hi genetic predisposition nei mite hi khawtlang nunah an tam zawk mai thei niin an ngai. Hei hi a chhan chu, gene nei mah se, an dam chhung zawnga chutiang reaction thlentu anesthetic drugs an hman loh chuan he dinhmun hi a lo awm ngai lo vang.

Hei hi eng symptoms nge ni?

Heng symptoms te hi operation lai emaw, operation hnu rei vak lovah emaw i dam lai hian a lo lang thei a ni. Mut lai leh anesthesia hnuaia heng symptoms te hi i neih chuan i hre lo ang. Mahse i anesthesiologist chuan a hrechhuak ngei ang. Surgery chhung zawng hian i vital signs te chu uluk takin an enfiah ang. Chuvangin heng symptoms te hi an hriat veleh enkawlna an tan nghal ang.

Engvangin nge hetiang hi a lo awm? A chhan chu eng nge ni?

Malignant Hyperthermia vei awlsamte hian an taksa ruh cell-a protein thenkhatah genetic change, chu chu genetic mutation an nei a. Kan taksa ruh cell-te hian an chhungah calcium an dah khawm niin han ngaihtuah teh. He calcium chhuahna hi gate ang chi thilin a thunun a ni. Mi pangngai chu anesthetic drugs pek a nih chuan he gate hian controlled takin hna a thawk thin. Hei hian taksa ruhte a tikhawlo a, a tikhauh a, taksa insiamrem (metabolism) a chak tan a, taksa lumna pawh hlauhawm takin a sang chho ta a ni. A tawpah chuan taksa ruh (muscle cells) te chu an thi a, thisenah hian potassium ang chi thil tam tak a awm khawm ta a ni. Heng avang hian symptom na tak dang a awm bawk.

Eng damdawi nge he reaction hi a thlen thin?

Hetiang dinhmun hi damdawi chi hnih avanga lo awm a ni ber.

• Inhaled anesthetics hmanga damdawi hman thin:
• Halothane a ni
• Desflurane a ni
• Sevoflurane a ni
• Isoflurane a ni
• Damdawi thisen zam : 1.1.
• Succinylcholine (hei hi taksa chakna ti hahdamtu a ni) .

Engtin nge hei hi i hriatchhuah a, i nemnghet?

Surgery neih laiin hmuhchhuah a ni

Surgery neih laiin hmuhchhuah a ni fo. Hetiang natna hi i nei tih i hriat loh chuan i anesthesiologist pawhin a nei lo ang. Mahse, operation chhung zawngin a enkawl reng ang che a, a hnuaia inthlak danglamna te hi an hriat chuan malignant hyperthermia a rinhlelh mai thei bawk:

• Chhan awm lovin heart rate a sang.
• Taksa lumna sang lutuk .
• Carbon dioxide chhuak tam lutuk.
• Muscle a nghet lo.

Anesthesiologist-te chu heng inthlak danglamnate hi rang taka hre thei tura zirtir an nih avangin enkawlna an tan thuai thei a ni.

Risk a awm leh awm loh hriat lawk theih a ni em?

I chhungkaw history avanga he risk hi i nei nia i rinhlelh chuan a finfiah nan special test engemaw zat a awm a ni.

• Caffeine Halothane Contracture Test (CHCT): Hei hian i taksa ruh te tak te (muscle biopsy) lak a, laboratory-a halothane gas leh caffeine te nena inhmuhna a ni. Muscle piece-in a chhân lêt dân hmangin he natna hi i vei duh em tih hriat theih a ni.
• Genetic testing: He test hi thisen sample lak a ni a, Malignant Hyperthermia nena inzawm genetic mutations (e.g., RYR1, STAC3, CACNA1S) a hmuchhuak thei a ni.

Mahse heng test te hi a man a to deuh a, Sri Lanka hmun tinah a awm lo. Chuvangin, emergency surgery i neih a ngai a, i chhungte zinga mi tu emaw chuan hetiang dinhmun hi a nei a nih chuan doctor-te chuan test an nghak lo vang a, nangmah ah hian he reaction awm lo tur safe anesthetics chauh an hmang ang .

Engtin nge enkawl a nih?

Malignant hyperthermia a awm chuan damdawi hman ber leh nunna chhanhimtu chu dantrolene a ni . Anesthesiologist chuan he natna hi a rinhlelh veleh he damdawi hi thisenah an pe nghal a ni. Chutih rual chuan, .

• Reaction thlentu anesthetic chu tihtawp nghal a ni.
• Surgeon hnenah hriattir a ni ang a, a rang thei ang bera zai zawh a ni ang.
• To reduce high body temperature , cold IV fluids chu veins-ah dah a ni a, taksa chu ice pack ang chi thil hmangin a lum a ni.
• Oxygen a pe thin.
• Heart rhythm disorder a enkawl thin.

Condition chu control a nih hnuah intensive care unit (ICU)-ah ni khat tal dah i ni ang a, chutah chuan medical team-in an enkawl ang che. Hemi chhung hian thisen test tam zawk an nei ang a, a tul angin enkawlna dang an pe bawk ang.

Dinhmun chu eng ang nge ni ang? Eng harsatna nge a awm?

Medical team-in he natna hi rang taka an hriatchhuah a, dik taka an enkawl chuan a dam kim thei a ni. Hei atanga harsatna lo awm thei te chu:

• Muscle tihchhiat a ni.
• Kidney tha lo a awm.
• Liver a tha lo.
• Thisen chhuak.
• Lung natna (Cardiac arrest) a awm.
• Seizures a awm thin.
• Coma-ah a lut ta.
• Thihna.

Malignant Hyperthermia hi enkawl loh chuan a thihpui fo thin. Enkawlna mumal tak awm pawhin thihna hi 3% leh 5% inkar a ni.

Hei hi ven theih a ni em?

Ni e, ven theih a ni! Chutianga tih theih dan tha ber chu nangmah leh i doctor tana i risk hriat hi a ni. Hemi nena inzawm genetic mutation i nei tih i hriat chuan, emaw, i chhungkuaa mi pakhatin he natna hi a nei tih i hriat chuan, operation hmain anesthesiologist hnenah i hrilh hmasa tur a ni. Tichuan anesthesia a pek che chuan chutiang damdawi hlauhawm tak tak ai chuan damdawi him tak tak a hmang ang. Tichuan chu thil hlauhawm tak chu a thleng dawn lo. Mi tam tak chuan he risk hi an nei tih hi an chunga a thlen hnuah chauh an hrechhuak thin. Chuvangin i chhungkaw medical history hriat a pawimawh em em a ni. Malignant Hyperthermia, anesthesia, surgery, anesthesia reaction, genetic disease, dantrolene, chhungkaw chanchin, operation himna, anesthesia complication, genetic natna