I naute hian hetiang hian spot a nei em? Neonatal Lupus chungchang hi i zir dawn teh ang!

I nausen piang thar taksaah hian a sen deuh deuh i hmuh thut a nih chuan, emaw, doctor-in i naute heart rate chungchang eng emaw a sawi chuan hlauhna tlem i neih chu thil pangngai a ni. A chang chuan heng thilte hi Neonatal Lupus an tih natna avanga lo awm thei a ni. Vawiin hian he thu hi chipchiar deuhin kan sawi dawn a, i thianpa i biak ang bawkin.

Neonatal Lupus hi eng nge ni?

A awlsam zawngin sawi ila, Neonatal Lupus hi naute chu a pum chhungah (fetus) emaw, a pian hnu lawkah (nausen) emaw a nghawng thei a ni. A tam zawkah chuan hun eng emaw chen, harsatna awm lo, vun rawng ang chi inthlak danglamna a thlen thin. Chungte chu naute kum khat a tlin hmain anmahni chauhin an bo tlangpui. Mahse, a chang chuan Neonatal Lupus hian naute thinlung a nghawng thei a ni.

Hetiang a nih chuan harsatna hlauhawm ber chu ``autoimmune congenital heart block.`` a ni.`` Chu chu he ``Neonatal Lupus`` hian naute thinlung a thawk tha thei lo tihna a ni. He heart block hi a nasat ber a nih chuan nunna atana hlauhawm tak a ni thei a, mahse enkawl theih a ni fo.

I naute hian Neonatal Lupus a vei tih hmuhchhuah a nih chuan i naute enkawltu team-te thupek uluk taka zawm a pawimawh. Diagnosis hian i naute a nghawng dan tur leh enkawl a ngai dawn em tih te an sawifiah ang.

Hei hi puitling lupus (Systemic Lupus Erythematosus - SLE) nen a inzawm em?

Ni lo, an pahnih hi tibuai suh. Neonatal Lupus hi Systemic Lupus Erythematosus (SLE) nen a inang lo a, chu chu lupus kan ti tlangpui. A chhan leh a enkawl dan pawh a danglam hle.

Neonatal Lupus hi antibodies chi hrang hrang, anti-SSA, anti-SSB, leh anti-U1-RNP te chu nu atanga naute hnena placenta kaltlangin a lo awm thin a ni. Heng antibodies te hi a takah chuan kan taksa chhunga cell hrisel tak takte bei sual palhtu protein an ni. A tam zawkah chuan heng antibody te hian nausen pum chhunga seilian chu a nghawng lo. Mahse a chang chuan, naute cell hrisel, a bik takin thinlung cell te chu an bei thei a ni.

Neonatal Lupus hi naute nuin heng antibodies bikte hi an nei chauh a ni. Hei hian a nu hian autoimmune disease a nei tihna a ni tlangpui. Entirnan, Sjögren’s syndrome, SLE emaw, mixed connective tissue natna emaw a ni thei. Mahse, a chang chuan heng antibodies te hi taksaah hian symptom awm lovin a awm thei a ni. Thil engemaw takah chuan Neonatal Lupus hi nuin heng antibody pakhat emaw a aia tam emaw a neih thu leh nakin lawkah active autoimmune disease a neih theihna tur chhinchhiahna hmasa ber a ni thei.

Autoimmune disease i neih chuan i naute hian Neonatal Lupus a vei ngei ang tihna a ni lo tih hre reng ang che. Dik tak chuan i naute hian Neonatal Lupus a vei loh a rinawm zawk. Mahse, hei hi i hriat chian a ngai a, i doctor nen pawh i sawipui tur a ni.

Hetiang dinhmun hi engtiang chiahin nge a awm?

Neonatal Lupus hi thil mak a ni lo. A harsatna na ber, autoimmune congenital heart block hian nu naute piang zinga 2% aia tlem lo, anti-SSA, anti-SSB, emaw anti-U1-RNP antibodies positive te a nghawng a ni. Mahse, naupai hmasaah autoimmune congenital heart block i nei tawh a nih chuan naupai hnua i neih leh theihna chance a sang zawk.

`(Neonatal Lupus)` natna lan chhuah dan chu engte nge ni?

A chhinchhiahna langsar ber chu vun rawng a ni. Hei hi pian tirh lamah hmuh theih a ni a, a nih loh leh dam chhung thla engemaw zat chhungin a lo lang thei bawk. He rash hi hun eng emaw chen atan a ni a, a hlauhawm lo. Ring zungbun ang maiin a lang a, a sir chu a rawng (a tam zawkah chuan a sen) a ni. Ring tin hian center chiang tak (i.e., vun rawng pangngai) an nei vek a.

Heng hliamte hi i naute lu vun leh hmaiah i hmu ngei ang. Mahse, rilru, kut leh ke-ah te pawh an lang thei. Heng hliam te hi ``subacute cutaneous lupus'' tih dinhmuna hmuh te nen a inang a, chuvang chuan ``neonatal lupus'' an ti a ni.

Hun rei lote chhunga awm leh hlauhawm lo symptom dang pawh a awm bawk. Anni chu:

• Thisen sen (red blood cell level) a tlahniam (anemia).
• Platelets (thisen tichhe thei cell) (thrombocytopenia) level hniam.
• Thisen var (white blood cell) a tlem (neutropenia).
• Liver enzyme level sang tak a ni.

Heng symptom zawng zawng hi nu atanga antibody te chu naute taksa atanga lakchhuah vek a nih chuan a bo vek a ni. Thla 6 leh thla 9 inkar ah an tha tlangpui.

Nausen piang thar Lupus leh Heart Block

Kan sawi tawh ang khan Neonatal Lupus hian harsatna lian tak, autoimmune congenital heart block an tih chu a thlen thei a ni. Hei hi naute thinlung electrical system-a harsatna a ni. Naute lungphu chu electrical impulse hmanga control a ni a, chu chu thinlung chhungah a kal a ni. Neonatal Lupus-ah chuan nu atanga antibody lo chhuak hian thinlung electrical activity control tu cell group pakhat, AV node an tih chu a bei thin.

A châng chuan hei hian naute heart rate-ah danglamna tenau (first- or second-degree heart block) chauh a thlen ṭhin. Chungte chu pian hnuah a reh thei. Mahse, naute thenkhat chuan Neonatal Lupus vangin third-degree heart block, emaw complete heart block an nei thei a ni.

Hei hi thinlung chamber chunglam atanga electrical signal lo lut chu a hnuai lam chamber-ah a kal theih loh lai a ni. Heng signal te hi a block vek chuan thinlung chu a thawk mumal lo va, chu chuan naute thinlung tan taksaah thisen tling pump chhuah a harsat phah a ni. Third-degree heart block hi a na ber a ni. A chang chuan pian hma emaw, pian hnuah emaw thihna thlen thei a ni.

Heart block hi naupai kar 18 leh kar 24 inkarah a awm tlangpui. Doctor-te chuan naupai lai hian naute lungphu ngaithlain an hre thei a ni. Heart rate hi beisei aia hniam (bradycardia an tih) a nih chuan heart block chhinchhiahna a ni thei.

Neonatal Lupus hi engte nge ni?

Kan sawi tawh ang khan Neonatal Lupus hi nu atanga naute hnena nausen (placenta) kaltlanga antibodies kaltlanga lo awm a ni. Researcher-te chuan heng antibody chi hrang hrangte hi Neonatal Lupus nen an inzawm tir a:

• `(Anti-Sjögren’s-syndrome nena inzawm antigen A (anti-SSA/Ro))`
• `(Anti-Sjögren’s-syndrome nena inzawm antigen B (anti-SSB/La))`
• `(Anti-U1 ribonucleoprotein (U1-RNP dotu))`

Heng `(antibodies)` te hi autoimmune natna chi hrang hrang nei, `(Sjögren's syndrome)`, `(SLE)`, `(rheumatoid arthritis)` leh `(mixed connective tissue disease)` te zingah hmuh tur a awm a ni. Amaherawhchu, heng `(antibodies)` te hi natna lanchhuahna nei lo emaw, natna vei hmuhchhuah loh emaw ah pawh hmuh theih a ni.

Heng antibody te hi naute taksaa an luh chuan hun eng emaw chen emaw, a awm reng emaw a tidanglam thei a ni. Heng antibodies te hian engtin nge heng inthlak danglamna hi an thlen tih hi zirchiangtute chuan an la hre chiang lo hle. Mahse, inthlâk danglamna lian ber leh awm reng chu naute thinlungah a ni tih an hria a ni .

Thinlung chhunga an luh veleh heng antibodies te hian inflammatory process an tan a, chu chuan scar tissue a siam chhuak thin. He scar tissue hian electrical signals te chu a block a, naute thinlung chu a thawk tha thei lo. A chhe berah chuan hei hi naupai laiin hriselna atana hlauhawm a ni thei a, nau piang hnuah pawh nunna atana hlauhawm tak a thlen thei bawk.

He natna `(Neonatal Lupus)` hi engtin nge an hriat chhuah?

Doctor-te chuan Neonatal Lupus hi naupai lai emaw, nau piang hnu lawkah emaw an hmuchhuak thin. Naute heart rate chu beisei aia hniam zawka an hmuh chuan fetal echocardiogram an ti ang. Hei hi test him, hrehawm lo, noninvasive a ni. Naute thinlung insiam dan leh hnathawh dan a en thei a ni.

He `(fetal echocardiogram)` hian `(Neonatal Lupus)` tilangtu inthlak danglamna a lantir thei. Chutiang a nih chuan i doctor chuan i natna nasat dan leh nakin lawka i beisei turte a hrilh ang che. I thisenah chuan chutiang special `(antibodies) te chu a awm leh awm loh an enfiah bawk ang.`

A chang chuan Neonatal Lupus symptoms, vun natna ang chi hi naute pian hnuah chauh a lang thin. Chutiang a nih chuan medical team chuan taksa enfiahna an nei ang a, chu chuan hliam awm chhan dang awm thei te chu an paih chhuak ang. Nangmah emaw, i naute emaw, in pahnih emaw pawhin antibodies an test thei bawk a, chu chuan natna hriat theihna a siam thei a ni.

I doctor chuan heng natna pahnih hi a awm chuan Neonatal Lupus i vei tih a hmuchhuak ang che:

• Nang leh/ emaw i naute chu `(anti-SSA)` leh/ emaw `(anti-SSB)` leh/ emaw `(anti-U1-RNP)` atan `(positive)` in nih chuan.

leh

• I naute hian ``Neonatal Lupus'' symptom pakhat tal a neih chuan.

Neonatal Lupus hi engtin nge enkawl a nih?

Enkawlna chu a natna nasat danah a innghat a ni. Vun natna, thisen cell zat dik lo, leh liver enzyme sang lutuk tan chuan enkawlna a ngai lo. Heng harsatnate hi kum khat pawh tling lovah a mah chauhin a reh tlangpui.

Mahse, naute heart block neia piangte chu an pian tirh emaw, an naupan lai emaw pawhin permanent pacemaker dah a ngai mai thei. Hei hi an thinlung thawk tha thei tur device implant na tur surgical procedure a ni. Hemi chungchang hi i naute medical team ten an hrilh belh ang che.

Research thenkhat chuan naupai laiin damdawi thenkhat ei hian i naute hian heart block a neih theihna a ti tlem thei tih an hmuchhuak. Autoimmune disease hmuhchhuah i neih chuan, emaw, antibody thenkhat i positive a nih chuan, i doctor chuan naupai laiin hydroxychloroquine tih damdawi ei turin a rawt thei ang. Chutianga tih chuan i naute chu Neonatal Lupus natna hlauhawm ber lakah a humhim thei ang.

Neonatal Lupus vei naute tan eng prognosis nge ni?

I naute thlir dan chu Neonatal Lupus hian a taksa a nghawng danah a innghat a ni. Naute vun, thin, leh/ emaw thisen dik lo chauh nei tan chuan thlirna a tha hle. Thla 6 atanga thla 9 chhungin engkim a pangngai leh tur a ni.

Mahse, heart block a awm chuan a hmalam hun chu a danglam thei hle. Heart block hian a chang chuan nau neih hma emaw, pian hnuah emaw thihna a thlen thei. Nausen heart block nei tam tak chuan naupan lai hian permanent pacemaker an mamawh dawn a ni.

Neonatal Lupus vei naute tlemte chuan a hnuah hetiang hian autoimmune condition an nei thei a ni:

• Naupangte zingah hian ruh natna (arthritis idiopathic arthritis) a awm
• Psoriasis natna a ni
• Autoimmune thyroid natna a ni
• Type 1 zunthlum vei a ni

"Naute tin hi an danglam vek. Neonatal Lupus hian i naute nunah nghawng a nei tlem hle emaw, nghawng a nei lo emaw pawh a ni thei. An medical team chuan beisei tur leh inbuatsaih dan tur chipchiar zawkin an pe ang che."

Neonatal Lupus hi ven theih a ni em?

Naupai lai hian antibodies te nausen (placenta) a paltlang theih lohna tur kawng a awm lo. Mahse, i naute thinlung chhiatna nasa tak chu i veng thei a, a tlem berah chuan i naute pian hnua enkawlna eng pawh i ruahman lawk thei bawk. Anti-SSA, anti-SSB, anti-U1-RNP i test positive chuan i doctor chuan a hnuaia mi hi a rawn rawt thei ang:

• Naupai tirh leh naupai laiin damdawi thenkhat ei hian naute chu heart block a neih loh nan a veng thei a ni.
• Naupai kar 16 vel atanga heart block (fetal echocardiograms) screening neih thin a ni.
• Naute pian tirh thla khat chhunga a thinlung hnathawh dan enfiah. Hei hi heart block chhinchhiahna (an la lang lo a nih chuan) enfiahna atan a ni a, naute thenkhat chuan an pian hnu kar tlemte hnuah chauh chhinchhiahna an lantir lo.

Engtikah nge damdawi lam thurawn ka lak ang?

I fa medical team-in test leh appointment schedule an pek chu dik taka zawm a pawimawh. I fa chu engzat nge checkup leh follow-up neihpui tur tih an hrilh ang che.

I hriselna enkawl a pawimawh bawk. Antibody thenkhat i test positive a, mahse autoimmune disease chhinchhiahna emaw symptom emaw i neih loh chuan i doctor chuan rheumatologist, ruh natna leh a kaihhnawih natna hrang hranga specialist doctor hnenah a refer thei che a ni. Hei hi a chhan chu kum engemaw zat chhungin active autoimmune disease i vei theihna chance a awm vang a ni. I doctor chuan i beisei theih turte a hrilhfiah ang che a, enkawlna i hmuh nghal theih nan uluk takin a enkawl ang che.

Ka fa doctor hnenah eng zawhna nge ka zawh ang?

Heng zawhnate hian Neonatal Lupus i hmuhchhuah hnuah i hriat belh theih nan a pui thei ang:

• Neonatal Lupus hian engtin nge ka naupai/ka naute a nghawng ang?
• Eng enkawlna kawng nge awm?
• Prognosis chu eng nge ni?
• Neonatal Lupus hian nakin lawka naupai tur a nghawng theihna chance engzat nge ni?

Puitlingte hian ``Neonatal Lupus'' an nei thei em?

Ni lo, Neonatal Lupus hi puitling tan chuan diagnosis a ni lo. Nausen leh nausen-ah chauh hmuhchhuah a ni. Neonatal Lupus hi puitling lupus nen a inang lo.

Systemic Lupus Erythematosus (SLE), lupus kan tih tlangpui hi autoimmune condition a ni a, naupang leh puitling pawh a vei a ni. SLE hi systemic a ni a, taksa pum a nghawng tihna a ni a, dam chhung enkawl leh enkawl a ngai a ni.

Neonatal Lupus hian naute dam chhung thla hmasa ber chauh a nghawng a ni. Naupan lai emaw, puitlin thlengin a lo thang lian lo.

Amaherawhchu, Neonatal Lupus hian mi taksaah nghawng rei tak a nei thei a, a pian hnuah chauh hriat chhuah a nih loh pawhin a taksaah nghawng rei tak a nei thei a ni. Harsatna lian ber chu heart block a ni a, dam chhung zawng pacemaker hman a ngai thei. Research thenkhat chuan naute Neonatal Lupus vei te chu an naupan laiin autoimmune diseases vei theihna chance a sang zawk thei niin an sawi.

Naupan lai khan Neonatal Lupus i vei a nih chuan, i upat deuh deuh chuan eng ang monitoring emaw testing nge i mamawh theih ang tih hriat tumin i doctor nen inbia ang che.

Naupai lai leh hetianga neonatal diagnosis i dawn hian a buaithlak thei a, a buaithlak thei bawk. I naupai chhoh zel angin eng nge thleng dawn tih hriat loh chu a harsa tak zet thei. I hlauhthawnna leh i lungkhamna te i medical team te hnena i sawi chhuah hi thil dik lo a ni lo. Eng thil nge thleng tih hrethiam turin theihtawp an chhuah ang a, naupai hrisel tak i neih theih nan eng nge i tih theih tih te chu an ti ang.

I naute hi a pian hnua a natna hmuhchhuah a nih chuan a dam chhung thla hmasa chhung zawnga enkawl a ngai mai thei a, a thinlung hnathawh dan enfiah a ngai mai thei. Tin, vun natna an nei thei bawk a, thla engemaw zat a daih thei bawk. I naute medical team chuan beisei tur an hrilhfiah ang a, nangmah leh chhungkaw pum tanpuina an pe ang.

He thawnthu atang hian kan hriat reng tur thilte

Okay, chuvangin Neonatal Lupus chungchanga kan sawi tawh thil pawimawh tak tak thenkhat kha han sawi nawn leh ila:

• Neonatal Lupus hi nausen piang tharte zingah nu atanga naute hnena antibodies bik pek chhuah avanga lo awm thin a ni.
• Hei hi puitlingah lupus (SLE) awm thin nen a inang lo.
• A tam zawkah chuan a lan chhuah dan hi hun rei lote chhung atan leh hlauhawm lo tak a ni a, vun natna ang chi hi a ni. Hengte hi thla 6-9 chhungin an dam leh ang.
• Mahse, naute ṭhenkhat chuan natna khirh tak, congenital heart block an tih chu an nei thei a, chu chu pacemaker hman a ngai thei a ni.
• Nuin autoimmune disease a neih chuan, emaw, antibodies bik (anti-SSA, anti-SSB) a neih chuan, naupai laiin doctor nen sawiho a pawimawh hle.
• Naute tam zawk chu he natna atang hian an dam chhuak vek thin. Lung lam harsatna a awm chuan enkawl theih a ni.
• Zawhna emaw rinhlelhna emaw i neih chuan Doctor hnenah zawh hreh suh. I tanpui turin an awm reng a ni.

`Neonatal Lupus, nausen piang thar, nausen natna, heart block, autoimmunity, nu antibodies, vun natna