He cancer hmuh tur awm lo tak, pum chhunga lining (peritoneal mesothelioma) lo awm hi i hria em?

A châng chuan i pum chhungah natna chiang lo tak emaw, pum puar emaw i nei ṭhin em? Ei duhna hloh leh taksa rihna tlahniam i nei em? Heng chhinchhiahnate hi a châng chuan ngaihthah mah ila, a hnuaia natna khirh tak chhinchhiahna a ni thei a ni. Vawiin hian cancer chi khat, tlem a tlem, mahse ngaihven hlawh tak chungchang kan sawi dawn a ni. Chu chu cancer pakhat `Peritoneal Mesothelioma` an tih a ni.

He Peritoneal Mesothelioma hi eng nge ni?

A awlsam zawngin, `Peritoneal Mesothelioma` hi kan pum chhungah cancer a lo awm a, chu chu pum chhung khuh tu membrane te tak te, damdawi lam atanga thlir chuan `peritoneum` a ni. Ngaihtuah teh, he `peritoneum` hi kan pum chhunga taksa peng pawimawh tak tak, thin, intestines, leh stomach vel vel venhimna khuh nalh tak ang mai a ni.

He cancer hi mesothelioma chi dang ang bawkin a hmaa asbestos an tih thil ei tawh nen a inzawm fo thin. Asbestos hi in sakna hmanrua thenkhat siamna atana hman thin a ni tih i hre tawh mai thei. A hlauhawm hle a, a chhan chu a chhunga fiber awmte hian i thawk emaw i ei emaw chuan harsatna lian tak a thlen thei a ni.

Peritoneal mesothelioma hi cancer natna hlauhawm tak a ni a, a darh chak hle bawk. A tam zawkah chuan hmuhchhuah a nih pawhin cancer hi pum chhunga lining zawng zawngah a darh vek tawh a ni. Chuvang chuan hriat hmasak a har hle.

Peritoneal Mesothelioma leh Pleural Mesothelioma hi eng nge an danglamna?

`Peritoneal Mesothelioma` leh `Pleural Mesothelioma` te hi kan taksa chhunga cavities pawimawh leh chhungril lam line siamtu membrane-ah te an lo thang lian a.

• Peritoneal mesothelioma hi pum chhunga awm leh pum chhunga taksa peng hrang hrang hualtu membrane-ah a lo awm a, chu chu kan sawi tawh ang khan peritoneum a ni.
• Pleural mesothelioma hi rilru chhunga awm, a bik takin lung chhunga line siamtu membrane-ah a lo awm thin. Pleura an ti a.

Heng membrane pahnih hi cell chi khat `mesothelial cells` an tih atanga siam a ni. Chuvang chuan he cancer hi `mesothelioma` an ti a ni.

Mesothelioma chi hnih hi a tlangpuiin malignant an ni a, cancer an ni tihna a ni . Heng malignant mesothelial cells te hi rang tak leh thunun theih lohvin an thang lian a, a chhehvel tissue hrisel tak tak te chu an tichhe thin. Pleural mesothelioma hi peritoneal mesothelioma aiin cancer chi khat a tam zawk.

He natna hi tuin nge vei tam ber? Engtiang chiahin nge a hluar?

Tu pawhin `Peritoneal Mesothelioma` an vei thei. Mahse, naupang tê tê zingah chuan a tlem hle. A tam zawkah chuan he natna hi kum 50 hnuai lam atanga hmuhchhuah a ni.

`Peritoneal Mesothelioma` hi `Mesothelioma` chi hnihna ni mah se (a hmasa ber chu `Pleural Mesothelioma` a ni), cancer hmuh tur awm lo tak a ni bawk. `Peritoneal Mesothelioma` hi `Mesothelioma` vei zawng zawng zinga 10% leh 20% inkar ah a awm thin. Ngaihtuah teh, America ang ramah hian kum tin heng damlo 400 leh 1000 vel chauh hi an vei thar an ni. Chuvangin, Sri Lanka-ah pawh heng damlote hi awm thei mahse, a tlem hle.

Peritoneal Mesothelioma natna lan chhuah dan chu engte nge ni? Engtin nge an hriat theih ang?

Hei hi thil pawimawh tak a ni a, a chhan chu a tam zawkah chuan Peritoneal Mesothelioma hian a tir lamah chuan symptom a nei lo. Cancer hian pum chhunga taksa peng hrang hranga a darh hnuah chauh symptoms a lang tan thin.

A lan chhuah dan tlangpui chu pum chhunga tui awmkhawm hi a ni. Hei hi `ascites` an ti bawk. Fluid a lo pun chuan pum chu a lian tan a, a hring tan bawk. A lan chhuahna langsar ber pahnihna chu pum na a ni.

A lan chhuah dan dangte chu:

• Ascites : Pum a khat a, a rit ang maiin a lang.
• Pum hring emaw, pum na emaw : Thawmhnaw a tight thei.
• Pum na : Hei hi pum chhung zawng zawnga darh na a ni thei a, a nih loh leh hmun khat chauha hriatna a ni thei bawk.
• I pum hnuai lamah lump na tak i nei thei .
• Constipation emaw bowel obstruction : I pum a puak ang maiin a awm a, ek chhuah harsa i ti hle.
• Nausea leh luak chhuak .
• Sawifiah loh taka khawsik leh zan lama thawk hah .
• Ngaihtuah phak loh khawpa taksa rihna tihtlem .
• Chaw ei chu a thlum lo .

Pawimawh: Heng symptoms pakhat emaw a aia tam emaw i neih chhunzawm chuan doctor pan a, thurawn lak a pawimawh hle. Lungngai suh, heng chhinchhiahna zawng zawng hi cancer avanga lo awm vek a ni lo. Thil awm dan tlangpui dang vang pawh a ni thei bawk. Mahse, check out neih hi a tha ber fo.

Peritoneal Mesothelioma vei chhan leh a hlauhawmna te chu engte nge ni?

Mesothelioma vei theihna tur risk factor ber chu asbestos nena inzawmna a ni. Asbestos hi fibrous material a ni a, construction, plumbing, electrical work, roofing, manufacturing industry thenkhat, leh automotive industry-a hman thin a ni. Mesothelioma vei tam tak chuan hna an nei a, chu chuan asbestos a tihbuai phah a ni.

Mahse, pleural mesothelioma (lung tichhe thei chi) vei tam zawk chuan asbestos exposure nei tawh mah se, peritoneal mesothelioma (abdomen lining tichhe thei chi) leh asbestos inzawmna hi a chiang lo hle. Mi thenkhat peritoneal mesothelioma vei te hian hnathawhna hmuna asbestos an hman tawhna history an nei lo mai thei. Hei hi zirchian mek a ni.

`Peritoneal Mesothelioma` vei theihna tur risk factor dang thenkhat chu hetiang hi a ni:

• Asbestos exposure : Kan chhehvela asbestos fiber a luh chuan boruakah a awm ta a ni. Chutianga an tih chuan kan hmui leh hnar hmangin kan taksaah an lut thei a, pum chhunga lining (peritoneum)-ah an kal thei a, chutah chuan an riak thei a ni. Vawikhat an lodge chuan mesothelial cells te chu an tichhia a, chu chuan a pangngai lo takin an inthen darh thin. Hei hian cancer natna (cancer tumor) a siam chhan chu a ni. Ngaihtuah teh, mesothelioma hi asbestos atanga kum tam tak hnuah a lo awm a, a then chu kum 40 vel a ni.
• Silica leh Erionite Exposure : Hengte hi leia mineral awm tlanglawn tak tak an ni. Hengte hi Pleural leh Peritoneal Mesothelioma pahnih nen pawh a inzawm tih hmuhchhuah a ni bawk.
• Gene mutations : Zirna thenkhatah chuan asbestos i tawk a, gene mutations thenkhat i neih chuan peritoneal mesothelioma vei theihna a sang thei tih hmuhchhuah a ni. Mutations awm tam ber pakhat chu BAP1 an tih gene inthlak danglamna hi a ni. He gene, BAP1 tia koh hian cancer lo thang lian tur venna hna a thawk a ni.
• Radiation exposure : A hmaa pum cancer avanga radiation therapy lo dawng tawh pawh hian peritoneal mesothelioma vei theihna a tipung niin an ngai bawk. Mahse, radiation leh mesothelioma risk inzawmna kimchang taka hriat chian nan zirchianna tam zawk neih a ngai a ni.

Engtin nge Peritoneal Mesothelioma i vei tih i hriat theih ang?

Peritoneal Mesothelioma hmuhchhuah hi a harsa thei hle a, kan sawi tawh ang khan, a chhan chu a tir lamah chuan a lan chhuah dan a lang lo fo thin. Symptoms a lan tak tak chuan gastrointestinal tract natna tlanglawn dang emaw, cancer chi dang emaw nen a inang thei a ni. Chuvangin, heng common conditions te hi diagnosis an siam hian an paih chhuak fo thin.

Natna hriat theih nan a hnuaia test te hi tih theih a ni:

• CT scan : I doctor chuan peritoneal mesothelioma ang chi symptoms dang, ovarian cancer emaw adenocarcinoma emaw awm thei te chu a awm loh nan CT scan a ti thei ang. Hei hian i thisenah dye him (contrast) inject a ngai thei a, chu chuan i pum chhunga lumps ang chi thilte chu scan-ah a langsar zawk ang.
• MRI scan (Magnetic Resonance Imaging (MRI)) : MRI hian CT scan ang bawkin detail level a pe thei a. Contrast nena CT scan i tih theih loh chuan MRI tih theih a ni.
• Thisen test a ni: I doctor chuan i thisenah marker thenkhat, protein bikte a test thei a, chu chu cancer tumor chhinchhiahna a ni thei.
• Peritoneal fluid analysis : Hetiang tih danah hian i doctor chuan i pum chhungah needle a dah a, chu fluid sample a la a, mesothelioma chhinchhiahna a awm leh awm loh a enfiah thin. Mahse, he test hian tihkhawtlai pakhat a nei a ni. I pum chhunga tui awm chungchang chauh a pe a, i pum chhunga tissue awm chungchang chauh a pe lo. Cancer stage hi cancer chu tissue-a a darh zat a innghat a ni.
• CT-guided core needle biopsy emaw laparoscopic biopsy : Peritoneal mesothelioma a awm tih finfiah theihna awmchhun chu biopsy neih hi a ni. Hetah hian i doctor chuan imaging (scan ang chi) hmangin i lump awmna dik tak chu a zawng chhuak thin. Tichuan, surgical instrument hmangin tissue sample an la a, lab-ah test turin an thawn a ni.

Peritoneal Mesothelioma hi eng stage nge ni?

Cancer stages hian natna hi eng chen nge a kal zel tih leh eng chen nge a darh tih a tarlang a ni. Peritoneal mesothelioma staging system hman tlanglawn ber chu PCI (Peritoneal Cancer Index) a ni.

`PCI` method ah chuan i pum chu section 13 ah then a ni a, section tin ah 0 atanga 3 thleng score pek a ni.

• 0 tih hian chu lai hmunah chuan cancer a awm lo tihna a ni.
• 3 tih hian a then chu cancer hian a khuh vek tihna a ni.

Chumi hnuah doctor chuan heng section tinte score te chu a add up a, cancer stage a ruat a ni. Stage 1 hi stage hmasawn lo ber a ni. Stage 4 hi stage hmasawn ber a ni.

• Stage 1: PCI score 1 atanga 10 thleng.
• Stage 2: PCI score 11 atanga 20 thleng.
• Stage 3: PCI score 21 atanga 30 thleng.
• Stage 4: PCI score 31 atanga 39 thleng a ni.

Peritoneal Mesothelioma hi eng enkawlna nge ni?

Enkawl dan tur chu i cancer stage, i hriselna zawng zawng leh thil dang engemaw zatah a innghat a ni.

Cytoreduction surgery leh HIPEC enkawlna (HIPEC hmanga Cytoreduction) .

Peritoneal mesothelioma enkawlna hman tlanglawn ber chu cytoreduction surgery leh hyperthermic intraperitoneal chemotherapy (HIPEC) hmanga enkawl a ni.

• Cytoreduction : Hei hi surgery a ni a, i pum chhung atanga cancer cells te chu a paih chhuak thin. Doctor-te chuan lump hmuh theih awm apiang chu an paih chhuak ang. Tin, cancer darh tawhna peritoneum leh abdominal organ thenkhat te pawh an paih chhuak thei bawk.
• Hyperthermic intraperitoneal chemotherapy (`HIPEC`) hmanga enkawl a ni.: Hei hi cytoreduction surgery hnua pek thin chemotherapy chi khat bik a ni. Chemotherapy damdawi te hi temperature him takah an lum a, pum chhungah direct-in an pe a ni. He lumna hian damdawi te chu chemotherapy pangngai aiin a tichak zawk hle. HIPEC hian cancer cell te tak te, operation neih chhunga lak chhuah loh awm tawh zawng zawng chu a that vek a ni. HIPEC hian chemotherapy pangngai aiin side effect a nei tlem zawk bawk.

Cytoreduction surgery leh HIPEC hi thil lian tak, buaithlak tak a ni a, darkar 10 aia rei a daih thei a ni. Mahse, zirchianna atanga a lan dan chuan he enkawlna hian Peritoneal Mesothelioma vei te chu an dam rei zawk a ni.

Chemotherapy hmanga enkawl a ni

Cytoreduction surgery leh HIPEC i tih theih loh chuan systemic chemotherapy pek i ni thei bawk. Systemic chemotherapy damdawi te hian i thisenah a kal a, i taksa pum puia cancer cell te chu a that thin. Chemotherapy damdawi chi hrang hrang pek dun theih a ni.

Immunotherapy hmanga enkawl a ni

Immunotherapy damdawi ``immune checkpoint inhibitors`` an tih hian nangmah ngeiin i immune system chu cancer cells zawng chhuakin a tichhe thei a ni. Heng damdawi te hi ``pleural mesothelioma.`` enkawlna atan hman thin a ni.I doctor chuan ``peritoneal mesothelioma.`` enkawlna atan pawh a pe thei bawk

Targeted therapy hmanga enkawlna

Peritoneal mesothelioma vei thenkhat chuan an cancer cell-ah hian genetic change an nei thei. Hei hi targeted therapies hmanga enkawl theih a ni. Targeted therapies hian cell hriselte cancer cell-a chantirtu genetic changes chu direct-a target-in hna a thawk a ni. Heng enkawlnate hi i enkawltu oncologist kaltlangin i hmu thei a, a nih loh leh enkawlna thar him leh him loh enfiahna clinical trial an tih zirchianna hmangin i hmu thei bawk. I biopsy atanga cancer tissue lakchhuahah hian genetic testing (gene testing) neih a pawimawh a, chu chuan i cancer hian heng targetable genetic changes te hi a nei em tih hriat a pawimawh hle.

Palliative care hmanga enkawl a ni

Cancer natna lan chhuah dan leh enkawlna avanga nghawng tha lo awmte enkawl dan tur chein i doctor chuan palliative care a rawt thei ang. Surgery atan i hrisel tawk lo a nih chuan, emaw, i cancer chu a lo sang chho tawh a nih chuan palliative care hi i tan a tha ber mai thei. Palliative care-ah hian paracentesis ang chi procedure te pawh a tel thei a, hei hian pum atanga tui a paih chhuak thin. Hei hian tui tam lutuk avanga natna leh natna awm chu a tihziaawm thei a ni.

Engtin nge he natna vei theihna hi i tihziaawm theih ang?

Peritoneal Mesothelioma vei theihna tihziaawmna awmchhun chuAsbestos laka inhriat loh nan. Kum 1970 chhoah khan United States-a Environmental Protection Agency (EPA) ang agency-te chuan asbestos hman dan tur dan an siam a. Mahse, chutiang dan hman a nih hmaa building sakah chuan asbestos a la awm thei tho. Asbestos fibers a tihbuai chuan boruakah a awm thei a, a tichhe thei hle.

I hlauhawmna tihtlem nân, asbestos laka inhnamhnawih thei thil siam ṭhat emaw, siam danglam emaw chu pumpelh suh. Chu ai chuan, chutiang hna thawk tûrin specialist, asbestos paih chhuaktu professional ang chi chu la rawh.

Peritoneal Mesothelioma natna vei lai hian eng ang beiseina nge i neih theih ang?

Peritoneal mesothelioma hi natna tihdam theih vek a ni lo. Mahse, enkawlna hian i dam chhung a ti rei thei a, remission hun engemaw chen pawh a thlen thei bawk. Mesothelioma enkawlna lama tui oncologist team nena thawhhona chuan i enkawlna result a ti tha thei a ni. Palliative care professional-te nena thawhhona hian he cancer diagnosis nena i nunpui hian i nunphung a tichangtlung thei bawk.

Eng thilin nge i prognosis a nghawng?

I natna hmalam hun tur hi thil engemaw zat ah a innghat a ni:

• Cell type : Cell chi thum a awm a, tumor-ah a lo thang lian thei a. A chi tlangpui ber, epithelioid cells tia koh hian cell chi dang pahnih sarcomatoid cell leh biphasic cells te aiin prognosis a nei tha zawk a ni.
• I mesothelioma stage : Natna hi a tir atanga hmuhchhuah a, enkawl a nih chuan a rah tha zawk i neih a rinawm.
• I gender : Peritoneal Mesothelioma chungchang sawi dawn chuan hmeichhiate hian mipa aiin prognosis an nei tha zawk tih hmuhchhuah a ni.
• Lumps te chu paih vek : I doctor chuan lumps zawng zawng a paih vek thei a nih chuan i prognosis a tha zawk mai thei.
• Thrombocytosis : Thrombocytosis i neih chuan i prognosis a tha lo thei. Thrombocytosis hi i thisenah platelet tam lutuk a awm a, chu chu i thisenah platelet tam lutuk a ni. Platelets hi i thisen zam tura puitu cell a ni.

Peritoneal Mesothelioma natna hi eng chen nge i dam theih ang?

Peritoneal Mesothelioma vei nia hriatte chu enkawl lohvin thla 6 atanga thla 12 vel an dam thei tlangpui. Mahse, enkawlna nen chuan damchhuahna rate chu a tha zawk hle. Peritoneal Mesothelioma vei, cytoreductive surgery leh HIPEC nei te chu an hmuhchhuah hnuah kum hnih atanga kum ruk chhung an dam thin. Mi thenkhat chu an dam rei zawk.

Mahse, i prognosis hi thil engemaw zatah a innghat a ni. I doctor hi i enkawl dan tur a zirin eng thil nge i prognosis tichhe dawn tih hrethiam tur chuan mi tha ber a ni.

I doctor zawh tur zawhna pawimawh tak takte chu engte nge ni?

Peritoneal Mesothelioma i vei nia hriat i nih chuan i doctor nen heng thilte hi sawipui rawh:

• "Tunge min enkawltu tur specialist doctor te chu?"
• "Palliative care team atanga tanpuina lak hi ka tan a tha zawk em?"
• "Eng mesothelioma nge ka neih?"
• "Ka cancer hi eng chen nge a darh? (Chu chu eng stage nge ni?)".
• "Eng enkawlna kawng nge ka neih?"
• "Kan tel theihna tur `clinical trial` (damdawi thar test-na zirchianna) a awm em?"
• "Enkawlna awm thei atang hian eng result nge ka beisei theih ang?"
• "Enkawlna hian eng side effect nge a neih? Engtin nge control theih ang?"

A tawp berah chuan thil hriat reng tur...

Peritoneal Mesothelioma hi cancer natna hlauhawm tak a ni a, mahse natna khirh tak a ni. Asbestos nena inzawmna hi a chhan lian tak a ni thei. Kan sawi tawh ang chi symptoms i neih chuan doctor pan vat a pawimawh.

Hetiang natna i hriat hian hlauhna leh lungkhamna i neih hi thil pangngai a ni. Mahse, nangmah chauh i ni lo tih hre reng ang che. Doctor, chhungte leh ṭhiante ṭanpui turin i nei a. A pawimawh ber chu thu dik tak dawng a, i doctor-te nen zalen taka inbiakna neih a, i tana enkawlna tha ber i hmuh hi a ni. Enkawlna hian i dam chhung a ti rei thei a, i nunphung pawh a tichangtlung thei ngei ang.

` Peritoneal Mesothelioma, cancer, pum cancer, asbestos, peritoneum, mesothelioma, HIPEC, natna lan chhuah dan, enkawl dan