Rabson-Mendenhall Syndrome hi eng nge ni? He dinhmun rare tak hi han sawi ila.

Kan taksaa thil thleng bulpui ber chu kan chaw ei hian chakna min pe a ni. Car chhunga gas dah ang mai a ni. Hetah hian kan taksa hian sugar (glucose) atangin chakna a hmu thin. He thil thleng zawng zawng hi hormone insulin tih hian a thunun a ni . He insulin hian thisen chhunga sugar awm chu chakna mamawh cell-ah thawn turin a hrilh a ni. Cell kawngkhar hawn a, sugar luh tir ang mai a ni a, mahse, Rabson-Mendenhall Syndrome vei taksaah chuan he thil hi a thleng dik lo. Chu chu an taksain insulin a hmang tha thei lo tihna a ni. Hei hi thil awmdan tlemte tak a ni.

Chuti a nih chuan he syndrome hi eng nge ni tak tak?

Insulin hian a hna a thawh that theih loh chuan naupang thanlenna kawngah direct-in a nghawng a ni. Ngaihtuah teh, hei hian a nghawng chu nausen a pian hma, chu chu nu pum chhunga a la awm lai pawhin a intan a ni. Hetiang natna vei naute hi an lian lo tlangpui. Nau piang hnuah pawh an thau chhoh dan leh an taksa than chhoh dan hi a zawi zawi hle. Damdawi lam hawi chuan Rabson-Mendenhall syndrome hi natna chi khat, pawl lian tak, severe insulin resistance syndromes an tih zinga mi a ni. Donohue syndrome leh type A insulin resistance syndrome te hi natna dang pahnih he pawla tel an ni.

Hetiang dinhmun a lo awm chhan hi eng nge ni?

A awlsam zawngin, hei hi genetic condition a ni. Chu chu nu leh pa atanga naupang hnena rochun a ni tihna a ni . Hei hi kan taksaa `INSR` an tih gene-a glitch awm vang a ni. Tunah chuan hetiang thil hi engtin nge a lo awm tih i lo en ang u. Kan taksa cell tinah hian gene tin copy pahnih a awm a. Pakhat chu nu hnen atangin, pakhat chu pa hnen atangin. Naupangin Rabson-Mendenhall syndrome a neih theih nan naupangin a dawn `INSR` gene copy pahnih hian a sawi dik lohna hi a nei vek tur a ni. Copy pakhat chauhin a chhiatna a neih chuan natna hi a lo awm lo ang. Phên dangin sawi ila, naupangin he natna a neih theih nân nu leh pa pahnih hian he gene chhia copy khat leh gene hrisel copy khat an neih a ngai a ni. Tichuan, naupang chuan an pahnih hnen atangin copy chhia pahnih chu accident-in a dawng tur a ni. Hei vang hian a tlem em em a, a chhan chu a tlangpuiin vawi li zinga vawi thum a thleng ngai lo.

Hetiang natna lan chhuah dan hi engte nge ni?

Naupang dam kum khatna atang hian natna lanchhuahna hi a lang tan tlangpui. Tin, heng symptoms nasat dan hi mi hrang hrangah a inang lo thei bawk. Simptom langsar tak tak hmuh theih te hi han thlir ila.

Hemi avanga natna dang lo awm thei te

Heng basic symptoms bakah hian he syndrome hian natna khirh tak dang a thlen thei bawk.

• Hmeichhe naupang ovary- a cyst awm.
• Zunthlum . Hei hian a châng chuan nunna atana hlauhawm tak, ketoacidosis , a thlen thei a ni.
• Kidney lama harsatna nei.

Engtin nge diagnosis hi siam a nih?

He natna hi hriatchhuahna atana harsatna pakhat chu natna dang, a inang (Donahue syndrome ang chi) atanga thliar hran hi a ni. I fa doctor chuan taksa chu uluk takin a enfiah ang a, i fa natna lan chhuah dan leh chhungkaw hriselna chanchin a zawt ang a, i fa thisen sugar leh insulin level enfiah nan thisen test vawi engemaw zat a ti mai thei bawk Hei chauh hi diagnosis dik tak siam theihna kawng awmchhun a ni.

Engtin nge enkawl a nih?

Rabson-Mendenhall syndrome enkawlna atan hian team lian tak, specialist hrang hrang, surgeon leh dentist hrang hrangte puihna a ngai tlangpui. Chhungkaw tan pawh he natna hlauhawm tak nei fa neih avanga lungkhamna leh rilru natna lo awm thinte enkawl nan counseling hi a pawimawh hle thei bawk. Enkawlna hi symptom tinrengah a bik takin a awm fo thin. Entirnan, Ovarian cyst paih chhuahna tur surgery, ha lama harsatna nei tan ha enkawlna, etc. A then phei chuan doctor-te chuan insulin hman tichaktu damdawi dang emaw, damdawi dang emaw dose sang tak an pe thin a, mahse hengte hi hun rei tak chhung atan chuan a hlawhtling lo fo thin.

Enkawlna thar chhui mek a ni

Mithiamte chuan insulin resistance na tak nena inzawm thisen sugar level sang (hyperglycemia) enkawlna kawng tha zawk an zirchiang chhunzawm zel a ni. Heng enkawlnate hian rah duhawm tak tak nei mahse, zirchianna neih belh a ngai a ni.

• Biguanides: Heng damdawi chi khat a ni a, taksain sugar a siam chhuah a tihtlem bakah insulin hman a tipung bawk .
• Leptin: He protein hian thisen sugar leh insulin level control nan a pui tih hmuhchhuah a ni.
• rhIGF-I (Recombinant insulin-like growth factor I): He protein hi ketoacidosis enkawlna atan hman a ni a, hei hi insulin resistance nasa tak avanga lo awm a ni .

Rabson-Mendenhall Syndrome, insulin resistance, genetic natna, naupang natna, acanthosis nigricans, ketoacidosis, zunthlum