I doctor-in hnute cancer i vei thu a hrilh che khan i treatment plan-ah ‘Taxane’ tih hming tarlan kha i hmu em? He hming i hriat khan i hlauthawng deuh a ni mai thei. He hming nen hian 'chemotherapy' tih thumal i hriat hian thil i rilruah a lo lang hi thil pangngai tak a ni. Mahse, lungngai suh. Taxane hi damdawi tha tak a ni a, kum 40 chuang zet hnute cancer enkawlnaah an lo hmang tawh a ni. I hriatthiam theih khawpin a awlsam zawngin sawi ila.
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Heng taxanes te hi engte nge ni? Engtin nge hna an thawh?
A awlsam zawngin sawi ila, taxanes hi chemotherapy chi khat a ni a, cancer cells te chu an inthen darh a, an lo pung zel a, taksa pum puiah an darh zel lo.
Ngaihtuah teh, kan taksaa cell hrisel te ang bawkin cancer cell te hi an inthen darh a, an pung chho zel a ni. Hetianga cell inthen darh dan hi an cell chhunga tube te tak te (microtubules) system pakhatin a pui thin. Damdawi taxane class, a dik zawk chuan antimicrotubule agents'' te hi chu tube system ngeiah chuan direct in an kal a, an target a ni. Heng damdawi te hian chu tube system hnathawh chu a tibuai a, a titawp bawk. Tichuan cancer cell te chu an inthen thei lo va, a tawpah chuan chu cell te chu an thi ta a ni. Hei hi he enkawlna bulpui ber a ni.
He enkawlna hi i enkawlna ruahmannaah chuan i neih ngei ngei tur a ni thei a, a bik takin (HER2-positive) chi hnute cancer i neih chuan.
Taxane damdawi (entir nan, (Docetaxel) leh (Paclitaxel)) hi chi hnih ah hian hman a ni:
1. Early-stage breast cancer: He damdawi hi surgery hmaa pek thin a ni a, chu chuan tumor chu a ti tlem a, a ti te zawk a ni. Cancer a lo let leh tawh loh nan operation zawhah pek thin a ni bawk.
2. Metastatic breast cancer: He damdawi hi taksa peng danga cancer darh tawh control nan pawh hman a ni.
Engtin nge Taxane damdawi hi pek thin?
Tunah hian Taxane damdawi hi thisenah pek a ni (IV) , chu chu saline solution angin vein-ah pek a ni tihna a ni. Hei hi damdawi inah emaw, cancer clinic-ah emaw tih a ni.
A chang chuan taxanes chauh pek thin (monotherapy). A châng dangah chuan a enkawlna a hlawhtlin theih nân chemotherapy damdawi dang nêna inkawpin an pe bawk. Entirnan, Capecitabine, Carboplatin, leh Cyclophosphamide ang chi damdawi te nen pek dun an ni.
Thu lawmawm tak chu scientist-te chuan he damdawi hi pill anga ei dan tur an zirchiang mek a, hei hian nakin lawkah damdawi ina tlawh a tihtlem phah thei a ni.
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Check Availability →Enkawlna i dawn hunah eng nge i beisei ang?
I doctor chuan taxane hmanga enkawl tan a tum chuan i tan enkawlna tur bik an siamsak ang che. Hei hian damdawi inah vawi engzat nge i lo kal a ngaih tih leh damdawi i dawn hun chhung chu a huam tel a ni.
- Enkawlna zat: Hei hi mi hrang hrangah a inang lo. Damdawi chi hrang hrang ((Docetaxel) emaw (Paclitaxel) emaw), damdawi dose leh i taksain a chhan danah a innghat a ni.
- Entirnan, (Docetaxel) hi kar 3 danah vawi khat pek thin a ni . Dose khatah darkar khat vel a ni.
- Paclitaxel hi tlem a tam zawk pek a ni. Kar hnih danah vawi khat tal pawh a ni mai thei . Darkar hnih vel a daih thei. Mi thenkhat tan kar khatah vawi khat dose hniam zawk pek thin a awm bawk.
- Dose: Damdawi pek zat hi thil engemaw zatah a innghat a, chung zingah chuan i cancer chi leh a stage, i rih zawng leh i san zawng, leh eng damdawi dang nge i pek tih te pawh a tel.
- Enkawl hun chhung: Hei hi enkawlna hlawhtlinna leh side effect na tak i neih leh neih lohah pawh a innghat bawk. A tlangpuiin cancer darh lo tan chuan cycle thum atanga vawi ruk chhung enkawl thin a ni. Cancer darh tawh chu enkawl rei zawk a ngai mai thei.
Mahse, side effect na tak i neih emaw, damdawi i tuar theih loh emaw chuan i doctor chuan enkawlna dang a thlak thei che tih hre reng ang che.
Taxanes hian side effect a nei em?
Awle. Vanduaithlak takin chemotherapy damdawi zawng zawng ang bawkin taxanes hian side effect a nei thei a ni. Hei hi a chhan chu heng damdawi te hian cancer cell chauh ni lovin, cell hrisel tak tak, rang taka inthen darh te pawh a nghawng vang a ni. Mahse, a tam zawkah chuan taxanes hian chemotherapy damdawi dang nena khaikhin chuan a side effects hi a tlem hle a, a tuar theih bawk.
Heng side effects te hi a tenau atanga na tak thlengin damdawi ina dah ngai thlengin a awm thei. Heng side effects te hi eng nge ni tih han thlir ila.
| Taxane hmanga enkawlna avanga side effects awm thei | |
|---|---|
| Side effect awm fo thin | |
| Chau | A tam zawkah chuan i chau hle mai thei. |
| Sam tlakchhamna | Lu chunga sam, chutiang bawkin taksa sam dang pawh a tla chhuak thei. |
| Muscle leh ruh natna | I taksa chu a na thei. Doctor-te chuan hei hi myalgia'' an ti. |
| Nausea leh luak chhuak | Hei hi control turin doctor chuan damdawi a pe ang che. |
| Ke ruh natna leh ke ruh natna | I kutphah, i kephah leh i kut zungtangteah tingling, kang, emaw, na emaw i nei thei. Hei hi peripheral neuropathy an ti a. |
| Kawngkhar natna | Kawng chhungah hliam te te a awm thei. |
| Hri kai theihna a tipung | Thisen var (neutropenia) tlahniam hian natna laka invenna a tizual thei a ni. |
| Side effect na tak tak, doctor hnena hriattir nghal tur | |
| Diarrhea na tak a awm | Diarrhea natna a tawp lo. |
| Ke ruh leh ke ruh chak lohna nasa tak | Kut chak lo lutuk thil chelh thei lo emaw, ke chak lo lutuk emaw kal theih loh. |
| Khawsik | Taksaah natna hrik a awm tih chhinchhiahna a ni thei bawk. |
| Vision a danglam thin | Mit hmuh fiah lo emaw, mit hmuhna hloh emaw. |
| Thisen chhuah dan pangngai lo | Hnar thisen emaw taksa pum puia hliam emaw. |
A tam zawkah chuan heng side effects te hi enkawlna tihtawp a nih atanga kar engemaw zat emaw thla engemaw zat emaw chhungin a bo vek thin. Mahse, mi thenkhat tan chuan neuropathy hi a nasat avangin a bo vek lo.
A pawimawh ber chu, natna lan chhuah dan danglam tak i neih chuan ngaihthah suh la, i doctor emaw, i enkawltu nurse emaw hnenah hriattir nghal rawh.
He enkawlna hi engtiang chiahin nge a hlawhtlin?
Taxane hi damdawi tha tak a ni a, chuvang chuan hun rei tak chhung chu hman a ni tawh a ni.
Cancer hmasa ber tan chuan:
Research atanga a lan dan chuan hmeichhe hnute cancer hmasa ber, operation nei te tan taxanes pek hian an damchhuahna a tisang a, cancer lo kir leh theihna a ti tlem bawk.
Metastatic breast cancer tan chuan:
Cancer a darh tawhna hmunah chuan taxane therapy hian cancer hi a tidam thei lo a, mahse natna kal zel dan tur control nan nasa takin a pui thei a, dam rei theihna a ti rei thei bawk.
He enkawlna hi (HER2-positive) cancer tan hman tam ber ni mahse, (Triple-Negative Breast Cancer - TNBC), cancer chi khat enkawl harsa tak tan pawh hman theih a ni.
Taxane hmanga enkawlna hian hna a thawh loh hun a awm em?
Ni e, a châng chuan a ti thei bawk. Cancer zawng zawng hian taxanes hi an chhang vek lo. Cancer thenkhat chuan a tir atang khan he damdawi hi an chhang lo mai thei. A châng dangah chuan, a enkawlnain hun engemaw chen a thawh hnuah, cancer chu damdawi chu a thiam tawh a, a do theihna (resistance) a nei ta a ni. Tichuan damdawi chuan hna a thawk tawh lo.
Hetiang dinhmun hi triple-negative'' cancer-ah chuan a tam hle. Scientist-te chuan hetiang thil hi a thlen chhan chiang takin an la hre lo.
Hetih lai hian i doctor chuan damdawi inkawp chu a thlak danglam thei a, a nih loh leh enkawlna dang tak takah a thlak thei che a ni.
Take-Home Thuchah a ni
- Taxane hi hnute cancer enkawlna atana chemotherapy tha tak a ni. Hei hi hlau suh.
- He enkawlna hi intravenous (IV) line hmanga pek a ni. Damdawi inah hun ruat bik siamin i kal a ngai dawn a ni.
- Side effects, sam tlakchham, hahna, leh taksa na te a awm thei. Chung zinga a tam zawk chu enkawlna tihtawp a nih veleh a bo vek.
- I taksa peng hrang hranga natna lan chhuahna na tak tak, khawsik, riltam na tak, emaw, i taksa peng hrang hranga chak lohna nasa tak i neih chuan doctor hnenah hriattir nghal rawh.
- Zawhna, hlauhna, rinhlelhna i neih apiang chu i doctor nen zalen taka sawiho chu i dikna a ni.
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