I asthma nena inzawm inflammation hi engtin chiah nge i enkawl? Kan sawi dun teh ang!

Asthma i neih chuan a chang chuan thawk harsa i ti mai thei. I rilru a tight tih hriat leh thawk hah hi asthma chhinchhiahna ber a ni. Hei hi a chhan ber chu i thawkna kawng chhunga a hring chhuak a ni a, a nih loh leh damdawi lama kan sawi thin `inflammation` . He inflammation hian i thawkna kawng a ti tawi a, mucus a khat a, thawk a harsa hle.

Asthma leh inflammation hi eng nge inzawmna?

Asthma i vei chuan he inflammation hian i thawkna kawng lining a ti hring a, mucus a tipung tih i hria mai thei. Tui pipe khar ang maiin ngaihtuah la, tui luang chhuak harsa tak a ni. He inflammation hian i thawkna kawng a ti sensitive hle. Tichuan, thil thenkhat (heng ``triggers`` kan tih) leivut, meikhu, leh rannung dander te hi i taksaah a luh chuan rang takin asthma a thlen thei a, chu chu asthma attack tihna a ni

Hei vang hian anti-inflammatory damdawi hi asthma vei tan chuan enkawlna pawimawh tak a ni. Asthma natna thlentu process chu an titawp thin. A awlsam zawngin, mei chunga tui dah ang mai an ni.

Asthma enkawlna tur engte nge ni?

Asthma natna avanga inflammation lo awm thin control nan hian damdawi chi hrang hrang hman theih a awm a. A bulpui berte chu:

• Corticosteroids chu thawkna kawngah direct-a inject thin (hei hi inhaler kan ti).
• Systemic corticosteroids (pill anga ei emaw, vein-a inject emaw) hi taksa pum a nghawng theih nan pek a ni.
• Hei bakah hian damdawi ``Mast cell stabilizers'' leh ``Leukotriene modifiers'' tih te pawh a awm bawk. Hengte hian ``Corticosteroids'' avanga inflammation awm thin chu a tihziaawm thei a ni.
• Enkawlna thar zawk chu ``Monoclonal antibodies'' emaw ``biologic therapy'' emaw a ni. Hengte hian inflammation-a inrawlh cell (``eosinophil cells'') te chu direct-in an target a ni.

Tunah chuan heng damdawi pakhat zel hi chipchiar deuhin kan sawi dawn nia .

Inhaled Corticosteroids: Asthma control na atana thian tha ber!

Inhaled corticosteroids hi i thawkna kawng a swelling leh mucus siam chhuah tihtlem nan damdawi tha ber a ni . Hetiang inhaler chi hi doctor-in asthma natna a pek hmasak ber a ni fo thin.

Hengte hman hian eng hlawkna nge a neih?

He inhaler hi dik taka hman hian hlawkna tam tak a nei a:

• Asthma symptoms leh flare-ups te a tlahniam thin.
• Short-acting beta agonists, emaw kan tih angin , relievers, emaw rescue inhalers te hi emergency-ah hman a ni a, hman a ngai zat pawh a ti tlem bawk.
• I lung hnathawh a tha zawk.
• Emergency room-a kal a, damdawi ina awm ngai chu a tlahniam dawn a ni.
• A pum puiin asthma hi a control tha thei hle.

Pawimawh: Hengte hi i hman hunah heng thilte hi hre reng ang che!

A pawimawh ber chu heng inhaled steroids hian asthma symptoms chauh a veng a, symptoms awmsa te chu a ti reh lo . Chumi awmzia chu Asthma attack i neih laia i ei chuan hahdamna i hmu nghal lovang tihna a ni. Chu chu reliever inhaler hi a ni.

He ``controller`` inhaler (kan tih ang hian) hi nitin hman tur a ni a, i doctor-in a tih angin . Mi thenkhat tan chuan ni khatah vawi hnih a ni thei a, thenkhat tan chuan ni khatah vawi khat a ni thei bawk. I natna lan chhuah dan a tha chho zel nia ngaiin, doctor nena inbiakna nei lovin hengte hi tihtlem emaw, hman tawh loh emaw chu thil tha a ni lo. Chutianga tih chuan i asthma chu a tizual leh thei a ni.

Heng hnar corticosteroid te hi engte nge ni?

Inhaled corticosteroids chi hrang hrang market-ah a awm a. Entirna thenkhat chu:

• ``Beclomethasone dipropionate (Qvar RediHaler®) hmanga tihdam theih a ni''.
• `Budesonide (Pulmicort®; Symbicort®) tih a ni a, a chhuahna tur hmun hi a inang lo hle. (He `(Symbicort®)` hi `(budesonide)` leh `(formoterol)` te inzawmkhawm a ni.)
• `Ciclisonide (Alvesco® HFA)` tih a ni
• `Fluticasone (Flovent® HFA; Advair® HFA leh diskus, Wixela® Inhub, AirDuo®)` a ni. (Hengte hian `(fluticasone)` leh `(salmeterol)` a pai a ni.)
• Fluticasone furoate (Arnuity® Ellipta; Breo® Ellipta; Trelegy® Ellipta) hmanga siam a ni. (Breo® hian fluticasone furoate leh long-acting beta agonist vilanterol an tih chu a pai a. Trelegy® hian heng pahnih bakah hian umeclidinium a pai bawk.)
• ``Fluticasone propionate (ArmonAir® RespiClick) hmanga tihdam theih a ni''.
• `Mometasone (Asmanex®, Dulera®)` tih a ni. (`(Dulera®)` hian `(mometasone)` a pai bakah `(formoterol)` a pai bawk.)

Engtin nge heng inhaler chi hrang hrangte hi a lo awm?

Heng ``(inhaled corticosteroids)`` te hi chi thum a awm a:

1. `(Metered Dose Inhaler - MDI)`: Hei hi can te tak te ang maia lang chi a ni a, a chungah i hmang thin. Hei hi hman dawnin `(valved holding chamber)` emaw `(spacer)` (Sinhala tawngin 'intermediate chamber' kan tih ang chi) nen hman a tha ber. He `(spacer)` hian damdawi chu lungah direct-a kal turin a pui a, ka leh ka chhunga damdawi awm zat pawh a ti tlem bawk. Hei hi tuikhuah atanga tui kan theh dawna tube hman ang mai a ni.

2. `(Dry Powder Inhaler - DPI)`: Hei hian damdawi chu dry powder angin a pai a. Thâwk la chhuakin hman a ni.

3. `(Nebulizer solutions)`: Hei hi liquid angin a lo thleng a. Machine te tak te (`(nebulizer machine)`) hmangin vaporized leh inhaled a ni. Hetiang hmanrua hi naupang tê tê leh asthma na tak nei te tan hman a ni fo.

Hengte hi hman ka hlau tur em ni? Side effect a awm em?

Inhaled corticosteroids hi puitling leh naupang tan pawh damdawi him tak a ni . Side effect hi a tlem hle a, a bik takin a tlem berah hman a nih chuan.

Mahse, a tlem hle a, a tam zawk i hman chuan ka chhungah fungal infection (thrush) a awm thei a, i aw pawh a danglam thei (a ri chhuak thei bawk). Hei hi ven a awlsam hle. Inhaler i hman apiangin i hmui chu uluk takin silfai la, gargle la, damdawi chu chhuah rawh . MDI i hman chuan spacer hmangin he risk hi i tihziaawm thei bawk. Thrush i vei palh a nih chuan awlsam takin i doctor-in anti-fungal mouthwash a pek hmangin enkawl theih a ni.

Engtin nge doctor hian hengte hi a pek?

I doctor chuan i asthma control thei tur he damdawi hi a dose hniam ber pek che a tum reng ang. Mi tam tak chuan "steroids" tih thumal an hriat hian an hlau hle. Hei hi a chhan chu anabolic steroids an hriat tawh vang a ni a, chu chu infiammiten taksa ruh siamna atana an hman thin a ni. Mahse asthma tan steroid hi chutiang chu a ni lo . Anti-inflammatory damdawi an ni. Dik tak chuan nitin ei hian i asthma chu a thunun thei a ni.

Systemic Corticosteroids: Asthma na tak tan a pui!

Heng ``Systemic corticosteroids`` te hi asthma episode na tak enkawlna atana hman thin damdawi te an ni. Pill emaw liquid emaw (``oral``) angin pek an ni a, a nih loh leh vein hmangin taksaah pek an ni (``intravenous - IV``).

Hengte hi engtik lai nge pek an nih?

He damdawi hi damdawi dang nen hman dun a ni a, chu chu asthma attack na tak tak, rang taka lo awm thin control nan emaw, hun rei tak chhung, control harsa tak, asthma enkawl nan emaw hman a ni.

Engtin nge hengte hian hna an thawh tan?

Systemic steroid hian hna a thawh tan nan darkar thum vel a hmang a, darkar ruk atanga darkar sawm leh pahnih hnuah a rah tha ber hmuh tur a awm. A châng chuan ni engemaw zât (steroid burst an tih) dose sang takin an pe ṭhin a, a nih loh leh hun kal zelah dose chu tihhniam zauh zauh a ni (steroid taper an ti bawk). A châng chuan hun rei tak chhunga control theih nân nitin emaw, ni hnih khatah emaw a tlem berah pek theih a ni.

Heng `(Systemic Steroids)` chi hrang hrangte hi engte nge ni?

``Systemic steroids'' chi hrang hrang hman tlanglawn tak tak a awm (hengte hi ``generic'' product angin pawh a awm):

• `Cortisone acetate` tih a ni
• `Dexamethasone` tih a ni
• `Hydrocortisone (Cortef®) tih a ni` tih hi a ni
• `Methylprednisolone (Medrol®, Solu-Medrol®, Depo-medrol®) hmanga siam chhuah a ni`
• `Prednisone (Deltasone®) tih a ni
• `Prednisolone (Prelone®, Pediapred®, Orapred®) hmanga siam chhuah a ni`

Side effects pawh kan hre tur em ni?

Systemic steroids hian hun rei tak hman a nih chuan side effects a nei tlangpui . Heng side effects te hi a hnuaia mi ang hian a ni thei:

• Acne a awm.
• Rihna a sang chho zel.
• Mood emaw nungchang emaw inthlak danglamna.
• Pum natna (e.g. gastritis) a awm.
• Ruh chak lo, ruh hloh.
• Mit inthlak danglamna, entirnan glaucoma (mit pressure sang) emaw cataracts (mit clouding) emaw a awm thei.
• (Naupang hming) than chak lohna.

Mahse, hun rei lote chhunga hman a nih chuan heng side effects te hi a tlem hle tih hre reng ang che . I asthma a nasat em avangin hun rei lote chhung chauh i hmang tur a ni. Asthma thunun theih loh i neih a, rei tak steroid i hman a ngai a nih chuan pulmonologist emaw allergist emaw i pan tur a ni. Enkawlna hmasawn zawk tur thutlukna siam turin an pui thei che a, a tul chuan specialist dangte hnenah pawh an refer thei bawk.

Leukotriene Modifiers: Ṭanpuina dang!

Chûngte chu eng nge ni? Engtin nge hna an thawh?

Leukotrienes hi kan taksaa pianphung anga awm chemical a ni. Kan thawkna kawng chhunga ruh (muscles) te chu a tikhauh a, mucus siamna a tipung bawk. Leukotriene modifiers hian leukotrienes te hnathawh a tikhawlo thin. Zirchianna atanga a lan dan chuan heng damdawi te hian thawk a ti tha thei a, asthma symptoms a ti tlem thei bawk. Tablet angin an rawn thleng thin. Ni khatah vawi khat emaw vawi hnih emaw ei thin a ni. Asthma damdawi dang i mamawh zat chu i tihtlem thei mai thei.

`(Leukotriene Modifiers)` hi eng chi nge ni?

Hemi category-a damdawi awmte chu:

• `Montelukast (Singulair®) tih a ni
• `Zafirlukast (Accolate®) tih a ni
• `Zileuton (Zyflo®)` tih a ni

Side effect a awm em?

Side effect langsar ber chu lu na leh luak chhuak a ni. Leukotriene modifiers hian damdawi dang thenkhat (entir nan, asthma damdawi theophylline leh thisen tithianghlimtu warfarin) nen pawh a inzawm thei bawk. Chuvangin i damdawi ei zawng zawng hi doctor hnenah hrilh vek a pawimawh.

Monoclonal Antibodies - Biologic Therapy: Asthma na tak tan beiseina thar!

Monoclonal antibodies hi biologic therapy chi khat a ni a, asthma na tak enkawlna atana hman thin a ni. Inflammation thlentu triggers laka taksain a chhanletna chu block-in hna an thawk a ni. Kan immune system-a tel cell, eosinophil cell ang chi te chu direct-in an target a ni.

Heng damdawi hi chi hrang hrang a awm a. Doctor office-a vun hnuaia injection angin emaw, clinic emaw damdawi inah IV infusion angin emaw, ṭhenkhat chu in lama mahni inject theih emaw an ni. Heng biologics ei thinte hian kar 2 atanga kar 8 danah enkawl an ni tlangpui (biologic a zirin). Heng damdawi te hi i ei a nih chuan pulmonologist emaw allergist emaw enkawlna hnuaiah i awm a ngai dawn a ni.

Mast Cell Stabilizers: Damdawi hman tlem tak a ni

Mast cell stabilizers hian mast cell atanga histamine leh inflammatory substance dang chhuak tur a tikhawlo a ni. Mahse, hengte hi Asthma enkawlna atan an hmang tlem hle.

I hriat reng tur ber chu!

Asthma hi i lung chhunga thawkna kawng a inflammation awm reng (chu chu persistent) a ni. A chhunga awm reng reng meialh te tak te ang a ni thei. Chuvangin, i doctor-in damdawi a pek che i ei hian i asthma chu i control tha thei a, hun rei tak chhung chu lung hrisel i vawng reng thei bawk.

Asthma natna nena nun hi thil harsa tak a ni thei tih hre reng la, mahse enkawl dan dik tak a awm chuan nun pangngai, active takin i hmang thei a ni. I doctor nen inbia la, i tana tha ber tur enkawlna ruahmanna siam rawh. Hrisel taka thaw lak dan tha ber a ni!

` Asthma, Inflammation, Inhaler, Corticosteroids, Enkawlna, Thluak lam natna