Hnute cancer chungchang hi kan hre tam emaw tlem emaw kan hre vek tawh. Mahse, hnute cancer chi hrang hrang a awm tih i hria em? A chi thenkhat chu enkawl a awlsam deuh a, a chi thenkhat erawh chu a na zawk leh a na deuh deuh bawk. Vawiin hian hnute cancer chi khat, tlem a na zawk, mahse uluk taka hriatthiam leh enkawl a nih chuan thunun theih a nih thu kan sawi dawn a ni. Hei hi doctor ten "Triple-Negative Breast Cancer" emaw `(Triple-Negative Breast Cancer - TNBC)` emaw an tih chu a ni.
Hei hi Triple-Negative hi eng nge ni?
A awlsam zawngin sawi ila, hnute cancer cells te tihpunna tura puitu thil pathum a awm a. Anni hi hormone estrogen leh progesterone te an ni a, protein pakhat HER2 an tih te an ni. Hengte hi cancer cell-a "kawngkhar" angin ngaihtuah rawh. Doctor-te chuan heng "kawngkhar" nena inmil "chabi" (i.e., hormone therapy ang chi damdawi) te hi an pe a, cancer a lo thang lian zel tur a titawp thin.
Mahse, triple-negative cancer-ah chuan cancer cell-te hian heng kawngkhar pathum (estrogen, progesterone, HER2) te hi an nei vek lo. Hei hian ‘negative’ an ni tihna a ni. Chu kawngkharte chu a awm loh avangin hormone enkawlna ang chi thil, a tlangpuiin he cancer chi hrang hrang tan hian a thawk thei lo. Hemi avang hian he cancer chi hi a na zawka ngaih a ni a, chi dang aiin a darh chak deuh hlek a ni.
Mahse hei hian enkawl theih a ni lo tihna erawh a ni lo. Ni miah lo! Enkawlna chak tak dang pawh a awm a, chu chuan a pui thei a ni. I doctor chuan i tana tha tur treatment plan a thlang ang.
He cancer natna lan chhuah dan hi engte nge ni?
Triple-negative breast cancer symptoms hi hnute cancer chi dang nen a inang fo thin. Heng symptoms zinga pakhat tal i neih chuan ngaihthah suh la, doctor pan nghal rawh.
| Symptom a ni | Hrilhfiahna awlsam tak |
|---|---|
| Hnute chhunga lump emaw thickening emaw a awm | Tun hmaa awm lo, i kut a i hriat theih tur lump thar. |
| Hnute emaw hnute emaw na/sen na | Natna awm reng emaw, a senna langsar tak emaw. |
| Nipple inversion emaw, chhuah emaw | A hmaa nipple pangngai chu a invert emaw, liquid (non-milk) a lo chhuak emaw a ni. |
| Hnute a hring chhuak | Lump chu palpable a ni lo thei a, mahse a hnute a then emaw, a pum emaw a hring thei. |
| Vun chu orange peel ang maia lang | Hnute vunah pores te chu a lian a, orange peel chunglam ang maiin a lang. |
| Armpit emaw arm vel emaw ah pimples a awm | Armpit area emaw, collarbone bulah emaw lymph node (nodules) a hring chhuak. |
| Hnute pianzia emaw, a lian zawng emaw inthlak danglamna | Hnute pakhat chu a dang nen a danglam tih hriat theih khawpin a lang. |
He cancer hi tute nge vei theihna sang zawk?
Doctor ten he cancer chi hi a chhan dik tak an la hre lo. Tin, a tlem hle bawk a, hmeichhe hnute cancer vei zinga 10%-20% chauh a nghawng. Mahse, mi thenkhat chu an hlauhawm zawk.
- Hmeichhia kum 40 hnuai lam .
- Mite chu BRCA gene mutation nei , a bik takin BRCA1 gene nei. Hei hi thlah kal zelah genetic change a ni.
- Hmeichhia thau lutuk leh menopause (thlasik chawlhsan) hnua exercise la lo .
Engtin nge cancer i vei tih chiang taka i hriat theih ang?
Doctor chauhvin eng cancer chi nge i neih tih chiang takin a hrilh thei che a ni. Hei hian test eng emaw zat a huam a ni.
1. Mammogram leh ultrasound scan: Hengte hian hnute chhunga lumps emaw, thil danglam emaw a hriat theih.
2. Biopsy test `(Biopsy)`: Hei hi a niTest pawimawh leh pawimawh ber chu rinhlelh awm tak lump atanga tissue te tak te tak te chu anesthesia hmanga lak a, specialist doctor hnena thawn a, chu chuan tissue chu a enfiah ang.
3. Tissue test: Tissue sample chu microscope hmangin an enfiah a, cancer a nih leh nih loh hriat theih a ni. Cancer a nih chuan a hmaa kan sawi tawh "kawngkhar" estrogen, progesterone, leh `HER2` tih te kha an enfiah thin. An pathum hian negative an nih chuan triple-negative cancer a ni tih hmuhchhuah a ni.
Cancer stage tihfel
Cancer a hmuhchhuah hnuah doctor chuan a "stage" a tichiang ang. Hei hian cancer hi engtiang chiahin nge a lian tih leh eng chen nge a darh tawh tihna a ni. Hei hian MRI, CT scan, leh PET scan ang chi test te a huam thei a ni.
`TNM` system hi khawvel pum huapa pawm dan a ni.
- T (Tumor): Tumor hi engzat nge a lian? (0-4 atanga score a ni)
- N (Nodes): Cancer hi a bul hnaia lymph node-ah a darh tawh em? (0-3 in score a ni) .
- M (Metastasis): Cancer hi taksa peng hla tak tak, lung, thin, emaw ruh emaw-ah a darh tawh em? (0 emaw 1 emaw) .
He stage atang hian doctor chuan eng damdawi nge i tan a tha ber tih a rel ang.
Enkawlnate chu engte nge ni?
Triple-negative cancer tan chuan enkawlna hrang hrang hman a ni tlangpui.
1. Chemotherapy hmanga enkawlna
Hei hi he cancer chi hrang hrang enkawlna ber leh pawimawh ber a ni. Cancer cells that thei damdawi chak tak tak taksa pek a huam a ni. A hmaa hmuhchhuah a nih chuan he cancer hian chemotherapy a dawng tha hle.
- Neoadjuvant Chemotherapy: Surgery hmaa pek thin, tumor tihtlem nan leh surgery awlsam zawk nan.
- Adjuvant Chemotherapy: Cancer cell la awm zawng zawng tihchhiat nan operation hnua pek thin chemotherapy.
2. Surgery tih a ni
Surgery hi chi hnih a awm a.
- Lumpectomy: Cancer natna hrik leh a chhehvela tissue tlemte lakchhuah.
- Mastectomy: A hnute zawng zawng lakchhuah. He cancer hi a nasat em avangin doctor-te chuan hnute pumpui (mastectomy) lak chhuah an rawt fo thin.
3. Radiation Therapy hmanga enkawlna
Surgery zawhah he enkawlna hi chu hmuna cancer cell awm thei zawng zawng tihchhiat nan leh cancer lo let leh tur venna atan pek thin a ni.
4. Immunotherapy hmanga enkawlna
Hei hi enkawl dan thar a ni. Heta kan tih hi kan taksa ngeia immune system stimulate , cancer cells hriatchhuah leh beih theihna tura puih hi a ni. Hei hi triple-negative cancer enkawlna hlawhtling tak a ni.
5. Targeted Therapy hman dan tur
Hei hi enkawl dan thar a ni bawk. "Smart bomb" ang mai a ni. Heng damdawi te hian an tih tur chu cancer cells te direct a zawng a, anmahniah an inzawm a, chemo chu cancer cells ah direct in an thlen thin a ni. Hei hi `Antibody-drug conjugate (ADC)' an ti bawk. Hei hian cell hrisel tak takte chu a tichhe tlem hle.
Dam leh theihna leh natna lo lang leh theihna chance
Hei hi mi tam tak tan chuan zawhna lian tak a ni. Mi hrang hrangah a inang lo avangin chhanna pakhat chauh pek a harsa hle. Dam leh theihna chance chu cancer hmuhchhuah hma dan leh taksain enkawlna a dawn danah a innghat a ni.
- Localized breast cancer tan chuan kum 5 dam theihna chance chu 91% vel a ni.
- A bul hnaia tissue (regional)-ah a darh chuan chu zat chu 65% vel a ni.
- Hmun hla tak takah a darh chuan chu zat chu 12%-ah a tlahniam a ni.
Heng statistics te hian hlauthawng suh. Hengte hi mi sang tam tak atanga averages chauh a ni. I dinhmun chu a ṭha zawk thei hle. A pawimawh ber chu a natna lan chhuah dan hriat chian a, a rang thei ang bera Doctor pan hi a ni.
Triple-negative cancer hi enkawl hnu kum 3 chhungin a lo lang leh thei a ni. Mahse, chu risk chu kum 5 hnuah a tlahniam chak hle. Chuvangin, enkawl zawhah doctor-in a tih angin follow-up test neih chhunzawm zel a pawimawh hle.
Take-Home Thuchah a ni
- Triple-negative breast cancer (TNBC) hi cancer chi khat a ni a, chi dang aiin a na zawk a, a darh chak zawk bawk.
- Hei hi a chhan chu heng cancer cell-te hian cancer tihpunna tura puitu hormone leh protein receptor an tlachham vang a ni.
- Hormone hmanga enkawlna pangngai hian hei hi a tihlawhtling lo nain, enkawlna tha tak tak, chemotherapy, surgery, radiation therapy, leh immunotherapy te a awm a ni.
- Nunna chhanhim nan a hma thei ang bera symptoms hriatchhuah hi a pawimawh hle. I hnute a inthlak danglamna reng reng chu ngaihthah ngai suh.
- I enkawl dan leh i cancer stage chungchang doctor hnenah zawhna zawh hreh suh. Engkim chiang taka hriat hian rilru chakna nasa tak a pe ang che.
- He zinkawngah hian nangmah chauh i ni lo. I chhungte leh i thiante thlawpna dawng rawh. I tan chakna ropui tak a ni ang.
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