He mana whakamiharo kei roto i ō tātou tinana! Ngā mea katoa e hiahia ana koe ki te mōhio mō te endothelium!

Kua whakaaro koe he aha ngā mea ririki i roto i ō tātou tinana, inā koa i roto i ō tātou uaua toto, e mahi ana mō tō tātou hauora? Āe, i tēnei rā ka kōrero tātou mō tētahi mea tino nui, engari kāore pea tātou e kōrero nui ana. Ko te endothelium tēnā. Ahakoa te ahua pūtaiao o te ingoa, he tino māmā noa iho. Me kōrero taipitopito tātou mōna, kātahi ka mārama koe ki tōna uara.

He aha te endothelium? Kia mārama tātou.

He whakarāpopototanga noa iho, ko tō endothelium he paparanga pūtau tino angiangi e whakarārangi ana i te roto o ō oko toto me ō oko lymphatic katoa . He rite ki tētahi kiriuhi iti e whakarārangi ana i te roto o tētahi paipa wai. Ka karangatia ēnei pūtau he pūtau endothelial . Kei hea rātou e noho ana?

• I roto i ō uaua .
• I roto i ōu uaua .
• I roto i ōu uaua toto .
• Ā, i roto hoki i ngā pūwero lymph .

Whakaarohia, ko te endothelium te mea e hono ana i tō toto ki te toenga o tō tinana, e tuku ana i ngā mōhiohio me ngā matūkai kia rere i waenganui i a rātou. Nō reira, he mea nui te endothelium ki ngā okana me ngā kiko katoa o tō tinana. Ehara te endothelium i te mea he uhi noa iho. He rite ki tētahi kaimahi pukumahi. He mahi pai tāna ki te pupuri i te rere pai o tō toto me te pupuri i te āhua pumau. Koia te take e whakaaro ai ngā kaipūtaiao ko te endothelium he okana endocrine . Inaa, ka miharo koe ki te mōhio koinei tētahi o ngā okana nui rawa atu o tō tinana! Ki te pā he mea ki ēnei pūtau endothelial iti, ka nui te pānga ki te tinana. Nā te mea he mahi pai tā ēnei pūtau ki te pupuri i a tātou kia ora, kia kaha hoki. Nō reira, he mea tino nui kia mōhio tātou ki tēnei endothelium me tana mahi. Kātahi ka taea e tātou te whakapau kaha ki te ārai i tēnei mea.

He momo endothelium kei reira?

Ae, e rua ngā momo matua e kōrerohia ana e tātou. He mea hanga ngā pūtau endothelial e rua, engari he iti noa ngā rerekētanga i runga i te wāhi kei reira rātou.

• Te endothelium toto: Koinei te arai o roto i ō uaua toto. He māmā noa iho, ko te endothelium te mea e āwhina ana i te rere o te toto.
• Te endothelium lymphatic:Kei roto tēnei i tō pūnaha lymphatic. He rite ngā oko lymphatic ki tētahi whatunga ngongo iti. Ka tangohia e rātou te wai nui (e kiia nei e tātou he lymph) e kohia ana i roto i ngā kiko. Nō reira, ka āwhina te endothelium o ēnei oko lymphatic i te nekehanga lymph.

He mea tino nui ēnei e rua mō te hauora o tō pūnaha manawa .

He aha te mahi nui a tēnei endothelium iti?

He rerekē te mahi a ngā pūtau endothelial i runga i te wāhi kei reira rātou i roto i te tinana. Me titiro tātou ki ngā mahi matua o te endothelium o ngā oko toto.

Te whaiti (Vasoconstriction) me te whānui (Vasodilation) o ngā oko toto

Ina he pūtau endothelial hauora ōu, ka āwhina rātou ki te pupuri i ō oko toto kia whānui (kia tuwhera) kia rere ai te toto i roto i a rātou me te kore he aukati. Ka aro atu hoki rātou ki ngā whakaohooho mai i roto, i waho hoki. Hei tauira, ko te pēhanga o te toto ki ngā pakitara o ō oko toto, ngā huringa o tō taumata ahotea, me ngā rongoā e tangohia ana e koe ka pā ki tēnei. Ka aro atu hoki rātou ki ngā huringa o te pāmahana. Whakaarohia, i te rangi makariri , ka whakawhāiti ngā oko toto i roto i ō waewae. Mā tēnei ka nui ake te rere o te toto ki ō whekau nui, kia mahana ai. I te rangi wera , ka whānui ake, ka pai ake te rere o te toto, ā, ka whakamatao i tō tinana. Ina whakakorikori koe , ka whānui ake ngā oko toto i roto i ō uaua, ka hoatu ki a rātou te toto me te hāora e hiahiatia ana e rātou. Nō reira, ahakoa te aha e mahia ana e koe, ka āwhina te endothelium ki te whakarite kia whiwhi ia okana me ia kiko i roto i tō tinana i te nui o te toto e tika ana.

Whakahaere i te nekehanga o ngā wai mai i te toto ki roto i ngā kiko

Ina ora, he āhua uru te endothelium. Arā, ka taea e ngā wai te haere mā roto i ōna pūtau ki roto i ngā kiko. Heoi, he ārai pai anō hoki. Ka ārai i ngā matū kāore e hiahiatia pērā i ngā paitini kia uru ki roto i te toto. Heoi, i roto i ētahi āhua mate, pērā i te mate pāwera / sepsis , ka paku uru te endothelium. Mā tēnei ka taea e ngā pūtau e whawhai ana ki te mate pāwera te uru ki roto i ngā kiko me te āwhina i a rātou ki te whakaora.

Ārai i te toto totoka koretake (Ārai i te Thrombosis )

Ko te thrombosis he āhuatanga e puta ai ngā toto totoka, e aukati ana i te rere o te toto, ka arahi pea ki ngā raruraru nui. Ka whakaputahia e tō endothelium ngā matū e kiia nei ko te hauota hauota me te prostacyclin . Mā ēnei ka noho angiangi tō toto, ka ārai hoki i te totoka. I ētahi āhua mate, kāore ēnei matū e puta tika ana. Ka piki ake te mōrearea o ngā toto totoka.

Kei hea tēnei endothelium i roto i tō tātou tinana? He aha tōna rahi?

Kua horapa tō endothelium puta noa i tō tinana! Whakaarohia, ko tō endothelium anake te mea kei roto i tō uaua toto.E 60,000 māero te roa o ngā uaua toto . Ki te tono koe ki tētahi kia whakaaturia mai tō ngākau, ka tohu rātou ki tō uma. Ki te tono koe ki tētahi kia whakaaturia mai tō roro, ka tohu rātou ki tō mahunga. Engari ki te tono koe ki tētahi kia whakaaturia mai te endothelium, ka tohu rātou ki tētahi wāhanga o tō tinana! Koinei te mea e tino motuhake ai te endothelium. Ko ngā pūtau endothelial te rārangi o roto o ō uaua toto. Ko ngā pūtau ēnei e pā tika ana ki tō toto. E piri ana rātou ki tētahi lamina basal . Ko te endothelium me tēnei lamina basal ngā mea e hanga tahi ana i te paparanga o roto rawa o te pakitara o ngā uaua toto, ko te tunica intima . Ko tēnei tunica intima te mea e āhei ai te rere pai o te toto. E hia te rahi o te endothelium? Ko tētahi o ngā okana nui rawa atu o tō tinana. Mō te horahanga o te mata, e kapi ana te tinana o te tangata toharite i tēnei mea, e kapi ana i waenga i te 3,000 me te 6,000 mita pūrua . Ā, neke atu i te 1 trillion ngā pūtau endothelial kei roto! He kiko epithelial ēnei. He aha te iti o ngā pūtau endothelial? Ka kitea noa ēnei pūtau mā te karuārai . Ko tō rātou rahi toharite ko:

• Tata ki te 30 ki te 50 maikoromita (micron) te roa.
• Tata ki te 10 ki te 30 maikiromita te whānui.
• Tata ki te 0.1 ki te 10 maikiromita te matotoru.

Hei whakaaro mō te rahi o tēnei pūtau, whakaarohia ō makawe ake. E 100 maikiromita te whānui o te makawe kotahi. Nō reira, ahakoa tōna roa rawa (50 maikiromita), he haurua noa iho te whānui o te pūtau endothelial i te makawe! Koia te take e taea ai e tātou te whai i te neke atu i te tiriona o ēnei pūtau motuhake i roto i ō tātou tinana.

He aha te rerekētanga i waenga i te Endothelium me te Epithelium?

He kiko hipoki ēnei e rua, engari he iti noa te rerekētanga.

• Kei roto i ngā awaawa o roto rawa o te tinana te endothelium , ā, kāore he hononga ki te taiao o waho. Hei tauira, ko ngā oko toto me ngā oko lymphatic.
• Kei roto i ngā ara e hono ana ki te taiao o waho te epithelium . Hei tauira, ko tō pūnaha nakunaku me tō pūnaha manawa .

He motuhake ngā mahi e rua mō ā rāua mahi. Ko te epithelium te mea nui ake hei tiaki , hei ārai i te ao o waho. Ko te endothelium te mea motuhake hei whāngai toto me ētahi atu matū ki te tinana.

A, mēnā kua pakaru te endothelium? He āhuatanga tēnā e kiia nei ko te ngoikore o te endothelial!

Ko te ngoikore o te endothelial ko te kore e taea e tō endothelium te mahi tika i tana mahi noa. Ka puta tēnei ina pakaru ō pūtau endothelial i tētahi mea. Ka puta pea tēnei kino i ngā momo mate hauora me ngā tikanga noho.

He aha pea te take o tēnei?

• Ngā mate urutā pēnei i te COVID-19 .
• Te pikinga o te huka toto (Hyperglycemia) .
• Te toto toto tiketike (hypertension) .
• Te pikinga o te taumata cholesterol i roto i te toto (Hyperlipidemia) .
• Te kore o te mahi ā-tinana.
• Te momi hikareti me te whakamahi tupeka .
• Ngā mate urutā kino pērā i te sepsis .

Ko te mea kino rawa atu ka puta ina pakaru te endothelium ko te atherosclerosis.

Ko te Atherosclerosis te whakaemi haere o te papaki i roto i ō uaua toto i roto i te wā. E mōhio ana ngā kaipūtaiao ko te wāhanga tuatahi o te atherosclerosis ko te kino o te endothelium. Ko te nuinga o te wā ka puta mai i ngā taumata tiketike o te LDL (cholesterol kino) i roto i te toto, te momi hikareti, te toto toto tiketike roa rānei. Ina pakaru tō endothelium, ka tīmata te pūnaha ārai mate o tō tinana. Ka tukuna e ia he momo toto ma e kiia nei ko ngā monocytes ki te pakitara o te uaua toto kua pakaru. Ka huihui ēnei monocytes ki reira ka puta te mumura i roto i te uaua toto. Kātahi ka puta he raupapa o ngā huringa pūtau, ā, ka mutu ka puta he mea e kiia nei ko te "fatty streak." Koinei te wāhi ka tīmata te hanga o te papaki. I roto i te wā, ka tipu tēnei papaki ka whakawhāiti i tō uaua toto. Ka whakaitihia te rere o te toto. Ehara i te mea koinā anake, engari ka whakanuia hoki e tēnei papaki te mōrearea o ngā toto totoka. Koia te take he nui ake te mōrearea o te hunga kua pakaru te endothelium ki te whakawhanake i ēnei mate.

He aha atu anō ngā mate ka puta mai i tēnei kino?

• Te mate o te uaua koronari
• Te whakaekenga o te ngākau
• Te Ischemia Myocardial (te whakahekenga o te rere o te toto ki te uaua o te ngakau)
• Mate o te uaua taha
• Ngā āhuatanga rite ki te whiu
• Te toto totoka ( thrombosis)

Ka taea hoki e te kino o te endothelial te whakanui ake i te mōrearea o:

• Matepukupuku
• Ngā mate pāwera
• Te Ātete ki te Insulin
• Mate whatukuhu

Nā, me pēhea tātou e pupuri ai i te hauora o tēnei endothelium utu nui?

Ka taea e koe te āwhina i te pupuri i ngā pūtau endothelial kia ora mā te whakaiti i te nui o ngā rauropi kore utu i roto i tō tinana. He ngota kore pumau ngā rauropi kore utu. Ka whakakino i ngā ngota hauora o te tinana. Ngā antioxidantsKo ngā antioxidants he matū e tiaki ana i tō tinana (ina koa te endothelium) mai i ngā rauropi kore utu. Nō reira, he mea tino nui te kai i ngā kai he nui ngā antioxidants. He nui ngā antioxidants i roto i ngā kai pēnei i ēnei:

• Raihi parauri (raihi parani)
• Ngā hua citrus pērā i te rēmana me te karaka me ō rātou wai
• Ngā huawhenua matomato pouri (pērā i te pīnihi, te kāreti)
• Ōti
• Pepa pere whero me te kōwhai (tīri ika)
• Kūmara
• Tōmato me te wai tōmato
• Ngā witi katoa

Ka taea e koe te pātai ki tō tākuta he aha ngā mea ka taea e koe te mahi hei tāpiri atu i ngā antioxidants ki tō kai. Tērā pea ka tukuna koe e tō tākuta ki tētahi tohunga kai. Ka taea e rātou te āwhina i a koe ki te mahi i ngā huringa iti e ngāwari ana te tīmata. Hei tauira, ka tūtohu pea rātou kia whai i tētahi kai Mediterranean, e mōhiotia ana ka āwhina i tō ngākau me ō uaua toto kia noho hauora.

He aha ngā mea e whakanui ana i ngā rauropi kore utu? Me pēhea tātou e tiaki ai i a tātou anō i aua mea?

Ka taea e ētahi āhuatanga hauora, ngā tikanga noho, me ngā paitini te whakanui ake i te nui o ngā rauropi kore utu i roto i tō tinana. Anei ētahi mea hei tūpato māu:

• Te parahanga o te hau.
• Ko ētahi rongoā, patupatu pepeke, me ngā kaihoroi wheketere.
• Te kai nui rawa i te huka.
• Kāore i te nui te moe.
• Te momonatanga .
• Auahi mai i ngā hua tupeka.

Kōrero ki tō tākuta mō te whawhai ki ēnei rauropi kore utu me te tiaki i tō tinana mai i ō rātou pānga kino. He mea nui anō hoki kia tirotirohia ā-tau koe e ngā tākuta , kia tangohia hoki ō rongoā kua tohua i te wā tika. Kōrero ki tō tākuta mō tētahi kaupapa whakakori tinana e tika ana mōu kia noho hauora ai koe. Ka āwhina ēnei mea i tō ngākau me tō pūnaha tohanga toto kia mahi tika. Ā, ka āwhina hoki ki te pupuri i te hauora o tō endothelium.

Kia maumahara, he āhuatanga mōrearea kei ia tangata ka taea te kino i te endothelium i tētahi wā o ō rātou oranga. Heoi, ka taea e koe te whakaiti i ēnei mōrearea mā te whai i tētahi momo noho hauora me te whakahaere i ō āhuatanga hauora.

Hei whakamutunga, ko ngā mea tino nui hei maumahara (Karere hei tango ki te kāinga)

Nā, ka kite koe ināianei ko te endothelium i kōrerohia e tātou i tēnei rā he wāhanga tino whakamiharo, he wāhanga tino nui hoki o tō tātou tinana. He rite ki tētahi e noho ana i roto i ō tātou uaua toto, e mahi puku ana mō te hauora o tō tātou tinana katoa.

• Ko te endothelium he paparanga pūtau e whakarārangi ana i te taha roto o ngā oko toto me ngā oko lymph.
• He maha ngā mahi nui a tēnei, pērā i te whakahaere i te rere o te toto, te ārai i te totoka, me te āwhina i ngā kiko ki te whakawhiti matū.
• Mena ka pakaru te endothelium (ka kore e pai te mahi a te endothelial), ka puta pea ngā mate kino pēnei i te mate manawa me te whiu.
• Ka taea e tātou te tiaki i tēnei endothelium utu nui mā te whai i tētahi kai pai, te whakakori tinana, te karo i te momi hikareti, me te whai i ētahi atu tikanga hauora.

Kōrero ki tō tākuta mō te hauora o tō endothelium, ā, mā roto i tēnā, te hauora o tō tinana katoa. He āwhina nui tēnei mō tō oranga hauora!