Kua rongo koe i tēnei mate e kikorangi ai koe i te makariri, ā, e tino ngenge ana koe? (Te Mate Agglutinin Makariri)

He kikorangi ō matimati me ō waewae i ētahi wā ina tino makariri koe? Kāore rānei he take e tino ngenge ana koe, e ngoikore ana hoki? Kua māwhero pea tō kiri. Mena kei a koe ēnei tohu, he mate onge pea te take, engari he mea tēnei me mōhio tātou katoa. I tēnei rā, ka kōrero tātou mō tēnei mate e kiia nei ko te 'Mate Agglutinin Makariri (CAD),' ko tōna tikanga he "mate kohikohinga pūtau toto makariri" i te reo Sinhala.

He aha te 'Mate Agglutinin Makariri (CAD)'? Kia mārama tātou.

Ki te kī māmā noa, ko te 'Mate Matao Agglutinin (CAD)' he mate toto onge e whakaekea hē ai e te pūnaha ārai mate o te tinana – te pūnaha e tiaki ana i a tātou i ngā mate pērā i ngā hōia i roto i ō tātou tinana – ō tātou toto whero hauora .

Whakaarohia, ko te tikanga, ka hangaia e tō tātou pūnaha ārai mate tētahi momo pūmua motuhake e kiia nei ko ngā 'antibodies' hei whakangaro i ngā huakita kino e uru ana ki te tinana. Engari i tēnei take o te CAD, ka hangaia e tō tātou pūnaha ārai mate tētahi momo 'antibodies' motuhake e kiia nei ko te 'autoantibody', e mōhiotia ana ko te 'cold agglutinin'. Ko te āhuatanga motuhake o tēnei ko tana whakaeke me te whakangaro i ngā toto whero hauora i roto i tō tātou tinana.

E mōhio ana koe, he momo pūtau tino nui ngā toto whero e kawe ana i te hāora puta noa i tō tātou tinana. Mā tēnei hāora ka āwhina i ō tātou pūtau ki te whakaputa i te pūngao e hiahiatia ana e rātou. Nō reira, ina heke te maha o ngā toto whero, arā, ina puta te anemia , ka pāngia tō tātou tinana e ngā momo mamae.

Ko te 'Mate Agglutinin Makariri' he rōpū anemia e kiia nei ko te 'anemia hemolytic'. Ko te 'anemia hemolytic' te wā e tere ake ai te pakaru o ngā toto whero i roto i te hinu wheua i te hanga i ngā toto hou. He rite ki te peere he kōhao kei roto, ā, ka tīmata te turuturu o te wai.

He pēhea te noa o te ingoa o tēnei mate e kiia nei ko te 'Mate Agglutinin Makariri'?

He tino onge tēnei mate . Tata ki te kotahi i roto i te 100,000 tāngata ka kitea houtia tēnei mate i ia tau. He mea noa tēnei i roto i ngā wāhine i waenga i te 40 me te 80 tau te pakeke. Heoi, ko te nuinga o ngā mate ka kitea i roto i te hunga kei waenganui i te 60 tau te pakeke.

He aha te pānga o te 'Mate Agglutinin Makariri' ki tōku tinana?

Ka taea e tēnei mate te whakararu i a koe ki ngā tohu o te anemia. Ko te anemia te wā kāore i te rawaka ngā toto whero o te tinana. I runga i te take, ka roa pea tēnei āhuatanga, ka poto rānei . Waihoki, ka rerekē ngā pānga ki te tinana mai i te ngawari ki te kino .

Hei tauira, ki te kore e tino kino te CAD, ka tino puhoi te puta o ngā tohu. Tērā pea ka roa ngā tau ka taea te tautuhi i te mate. Heoi, i ngā take tino kino, ka taea e te CAD te arahi ki ngā mate ngākau kino, tae atu ki te mate.Tērā pea ka tupu.

Kei roto i te ingoa o tēnei mate te kupu "makariri". Nō reira, ka tino kitea ēnei tohu i ngā rohe he makariri te āhuarangi, i ngā rā makariri rānei.

He aha ngā tohu o te 'Mate Agglutinin Makariri'?

He maha ngā wā e pā ana ngā tohu o te CAD ki te anemia me te rere kino o te toto puta noa i te tinana. Ko ēnei tohu ko:

• Te ngenge rawa (Te ngenge) : Ehara i te ngenge noa iho, engari he ahua kore ora.
• Ngoikore : Ka ngoikore rawa te tinana, kāore e taea e ia te mahi i tetahi mea.
• Whatiwhati : He āhua hurihuri.
• Te werawera : Te werawera kore noa iho.
• Te uaua ki te manawa (dyspnea) : Te uaua ki te manawa ahakoa he iti te kaha o te manawa.
• Ka piki ake te tere o te manawa (tachycardia) : Ka piki ake te tere o te manawa.
• Kōwhai : Ka ngaro te rere o te toto i te kiri, ā, ka mā.
• Ka kikorangi ngā maihao, ngā matimati, me ngā taringa ina pāngia e te makariri (te āhuatanga o Raynaud) : Ina haere koe ki tētahi wāhi makariri pērā i a Nuwara Eliya, ina pā atu rānei koe ki te wai matao, ka kikorangi ō maihao, ō matimati, me ō taringa, i ētahi wā ka mā. Tērā pea ka haere tahi tēnei me te ngoikore o te tinana.

Tērā pea ka puta he tohu o te jaundice . Ina whakangaromia ngā toto toto whero, ka tukuna he matū kōwhai e kiia nei ko te bilirubin. Ina nui haere tēnei bilirubin i roto i te tinana, ka puta te jaundice. Ko ngā tohu o te jaundice ko:

• Mimi parauri pouri.
• Āe, he kōwhai te mā o ngā kanohi me ngā karāhe.

He aha ngā take o te 'Mate Agglutinin Makariri'?

Ko te Mate Agglutinin Makariri he momo anemia hemolytic autoimmune. Ko te tikanga o tēnei ka whakaekea e tō tātou ake pūnaha ārai mate ō tātou ake pūtau. I roto i te CAD, ka whakahohehia tō tātou pūnaha ārai mate e ngā āhuatanga makariri, ā, ka puta he autoantibody e "tā" ana i ngā pūtau toto whero hei whakangaro i a rātou. Ka piri tahi ngā pūtau toto whero kua tātaitia, ka pūhui tahi (agglutinate). Ka taea te hopu ngāwari i ngā pūtau pūhui me te whakangaro e tētahi atu wāhanga o tō tātou pūnaha ārai mate, e kiia nei ko ngā macrophages.

Ka tīmata tēnei tukanga ina heke te pāmahana i raro i te 3-4 nekehanga Celsius (37-39 nekehanga Fahrenheit). Whakaarohia ko te pāmahana noa o tō tātou tinana he tata ki te 37 nekehanga Celsius. Ka tīmata tēnei raruraru ina pāngia tātou e ngā pāmahana he iti iho i tērā.

Ka whakararuraru te mate pukupuku o te wheua i te kaupapa noa mō te hanga toto whero hauora i roto i ō tātou tinana. I te nuinga o te wā, e 120 ngā rā e ora ai te toto whero. I tēnei wā, ka taea e tō tātou hinu wheua te hanga toto whero hou hei whakakapi i ngā mea e mate ana. Engari i roto i te mate pukupuku o te wheua, ka whakararuraruhia tēnei huringa.

Kāore anō kia tino mōhiotia e ngā kairangahau he aha i whakaeke ai tō tātou pūnaha ārai mate i ngā pūtau hauora.I ētahi wā, ka puta te CAD i tētahi atu mate hauora taketake. Ka kiia tēnei ko te 'CAD tuarua'. Ki te kore e kitea he hononga pēnei, arā, ka puta te CAD me te kore he take, ka kiia ko te 'CAD tuatahi' ko te 'CAD koretake' rānei.

He aha atu ngā āhuatanga ka hono atu ki te 'Mate Agglutinin Makariri'?

Ko te CAD tuarua e hono ana ki ngā mate pāwera, ngā mate pūnaha ārai mate, me ngā mate lymphoproliferative. Hei tauira:

• 'Mononucleosis pangia' (kirika repeure)
• Te niumōnia mycoplasma
• 'Te huaketo Cytomegalo'
• Lupus
• te rumatiki
• 'Te mate pukupuku kore-Hodgkin'
• Te mate toto totoka mau tonu
• "Makroglobulinemia o Waldenstrom"

Tērā pea he āhua pōhēhē ēnei ingoa ki a koe, engari he ingoa motuhake ēnei e whakamahia ana e ngā tākuta, nō reira he mea pai kia mōhio koe ki a rātou.

Me pēhea te tautuhi i te 'Mate Agglutinin Makariri'? (Tautuhinga)

Ka pātai tō tākuta mō ō tohumate, ka arotake anō hoki i tō hītori hauora. Kātahi ka tonoa e ia ētahi whakamātautau toto motuhake hei tirotiro mēnā he mate toto toto tōu, ā, mēnā he autoantibodies anō hoki e pā ana ki te CAD.

Ko ngā whakamātautau toto e whakamahia ana hei tautuhi i te anemia hemolytic ko:

• Te tatau toto katoa (CBC) : Mā tēnei ka hoatu he kōrero taipitopito mō ō toto whero. Ka taea e ia te tirotiro i te maha o ngā toto whero kei a koe, te rahi o aua toto, me te taumata o tō hemoglobin. He pūmua tino nui te hemoglobin e āwhina ana i ngā toto whero ki te kawe i te hāora.
• 'Tau o ngā Reticulocyte ': Ka ine tēnei i te maha o ngā toto toto whero kāore anō kia pakari ('reticulocytes') kei roto i tō tinana. Ina whakangaromia e te pūnaha ārai mate ngā toto toto whero kua pakari, ka ngana te tinana ki te hanga i ētahi atu o ēnei pūtau kāore anō kia pakari hei utu.
• Ngā whakamātautau taumata toto : Ko ngā taumata teitei o te 'lactate dehydrogenase (LDH)' me te 'bilirubin' i roto i te toto, me te heke o ngā taumata o te 'haptoglobin' he tohu o te 'anemia hemolytic'.

Kātahi, hei whakatau mēnā ko te CAD te take o tō anemia hemolytic, ka tirohia e tō tākuta ngā autoantibodies e whakaeke ana i ngā toto toto whero. Ko ngā whakamātautau e mahia ana mō tēnei ko:

• Whakamātautau Coombs Tika (DAT) : Ka tirohia e tēnei whakamātautau te aroaro o ngā autoantibodies e pā ana ki te CAD. I roto i te whakamātautau, ka wehea ō toto whero mai i te toenga o ō toto ka whakanohoia ki tētahi taiao whakahaeretia. Kātahi ka tāpirihia he otinga motuhake. Mena ka piri ngā toto whero ki te otinga ka piri tahi (agglutinate), ka pai te whakamātautau, ko te tikanga kei reira te autoantibody.
• `Whakamātautau i te tairite o te agglutinin makariri`Ka ine tēnei whakamātautau i te kukū, te rahinga rānei, o ēnei 'autoantibodies' i roto i tō toto. Ko te kukū teitei o ēnei 'autoantibodies' he tohu o te CAD.

Kia whakaūtia tō mate, ka tirohia anō hoki e tō tākuta mēnā he hononga tō CAD ki tētahi mate huna ('CAD tuarua').

Me pēhea te rongoā i te 'Mate Agglutinin Makariri'?

I runga i te kaha o ō tohumate, ka uru pea ki te maimoatanga ngā huringa momo noho, ngā rongoā, ā, i ētahi wā ko ngā whakawhiti toto i ngā wā ohorere .

• Te Āhua Noho : Mena he mate pukupuku tōu, tera pea ka tohutohu tō tākuta kia karohia e koe te makariri . Koinei te mea nui rawa atu. Me mahi koe i ngā mea pēnei i te mau i ngā kākahu mahana, te karo i te kaukau makariri, me te whakawhāiti i tō haerenga ki ngā āhuarangi makariri.
• Ngā Rongoā : Ko te rongoā e whakamahia whānuitia ana hei rongoā i te CAD ko te 'Rituximab' . Mā tēnei ka aukati i tō pūnaha ārai mate ki te hanga 'autoantibodies' e whakaeke ana i ō toto toto whero. Kua whakaaetia hoki tētahi rongoā hou e kīia ana ko 'Sutimlimab' . Mā tēnei ka aukati tika i te pūnaha ārai mate ki te whakaeke i ō toto toto whero.
• Te whakawhiti toto me te whakawhiti plasma : Mena ka kaha haere tō CAD, me tuku pea e tō tākuta he whakawhiti toto, he whakawhiti plasma rānei hei whakau i tō āhua. Ka mahi te whakawhiti plasma mā te whakaiti i te nui o ngā autoantibodies i roto i ō toto.

Mena he 'CAD tuarua' tōu, ka rongoāhia hoki e tō tākuta te mate taketake.

Ka taea te ārai i te CAD?

Engari, ehara te Mate Agglutinin Makariri i te mate e taea te ārai. Heoi, ka taea e koe te whakahaere i ngā tohumate me te noho ora pai.

Kia pēhea te roa ka taea e koe te ora me te 'Mate Agglutinin Makariri'?

Ko te hunga kua tātaitia he mate pukupuku o te roro (CAD) ka ora rite tonu ki te hunga o tō rātou tau kāore i te pāngia e te mate pukupuku o te roro. E ai ki tētahi rangahau tata nei, ko te hunga kua tātaitia he mate pukupuku o te roro i te 68 tau te pakeke ka ora pea ki te 80 tau te pakeke, i te toharite. Ko te tikanga, mā te maimoatanga me te whakahaere tika, ka taea e koe te tumanako ka ora pai koe.

He aha ngā pātai me pātai atu e au ki taku tākuta?

Mena kua tāpaetia koe kei te mate CAD, he mea pai kia pātai atu koe ki tō tākuta i ēnei pātai:

• He hononga tōku CAD ki tētahi mate huna?
• He aha ngā tohu hei āwhina i ahau ki te mōhio mēnā kei te pai haere, kei te kino haere rānei tōku āhua?
• Me haere tonu taku tango rongoā mō tēnei mate?
• He aha te āhuarangi pai rawa atu mō te tangata whai CAD ki te noho?
• He aha ngā awhe pāmahana me karo e au hei whakahaere i aku tohumate?

Ko tō wheako ki te Mate Matao Agglutinin (CAD) e whakawhirinaki ana ki te mea he tuatahi ('tuatahi') he tuarua rānei ('tuarua'). Ka pā anō hoki te kaha o ō tohu ki te kaha o te hiahia ki te maimoatanga. Mā te rongoā i te mate taketake, ka taea pea e tō tākuta te whakaora i tō CAD. Ahakoa he roa tō CAD, ka taea e koe te whakahaere i ō tohumate anemia me te noho ora mā te karo i te makariri me te tango i ō rongoā e ai ki te whakahaunga.

Ngā mea tino nui hei maumahara mai i ngā mea kua kōrerotia e tātou (Karere hei tango ki te kāinga)

• He mate onge te Mate Agglutinin Makariri (CAD) e whakaekea ai e tō tātou ake pūnaha ārai mate ō tātou toto whero, ā, ka kino haere i te makariri.
• Ko ētahi o ngā tohu ko te mamae o ngā hononga, te ngenge rawa, te kiri mā, te kikorangi o ngā maihao i te makariri, ā, i ētahi wā he kiri kōwhai .
• Ka taea tēnei te mea 'tuatahi' (kāore he take) te mea 'tuarua' rānei (nā tētahi atu mate i puta).
• He whakamātautau toto hei tātaritanga.
• Ko te maimoatanga pea ko te karo i te makariri, te rongoā, ā, i ētahi wā ko te whakawhiti toto.
• Ahakoa kāore e taea te ārai i tēnei, mā te whakahaere tika, ka taea e koe te ora i te oranga pai.
• Ki te pā mai ēnei tohu ki a koe, kaua e mangere ki te rapu tohutohu hauora. Mā te wawe o tō kitenga, ka māmā ake te rongoā.

Kia maumahara, he mea hei whakamōhio noa iho tēnei tuhinga. Mēnā he tohu kei a koe, me toro atu ki te tākuta mō ētahi tohutohu.

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