Kei te kōwhai haere tō kiri me te mā o ō kanohi? Me ako atu tātou mō te Mate Dubin-Johnson!

Kua kite koe i tētahi wā he āhua kōwhai te tae o tō kiri, o te mā rānei o ō kanohi? Kua kite rānei koe he pōuri ake te kōwhai o tō mimi i tō te tikanga? Mena kei te pāngia koe e ēnei āhuatanga, ko tētahi take pea he mate onge engari kāore i te tino kino e kiia nei ko te mate Dubin-Johnson . Nō reira, me kōrero taipitopito tātou mō tēnei mea, he tino māmā noa iho.

He aha te mate Dubin-Johnson?

Ki te kī ngāwari, ko te mate Dubin-Johnson he mate ira e pā ana ki tō tātou ate . Ko te mea ka tupu i roto i tēnei ko te kohikohi i tētahi matū kōwhai e kiia nei ko te bilirubin, e hangaia ana i roto i tō tātou tinana, kaua e tukuna tika mai i te tinana. Inaianei kei te whakaaro pea koe he aha te bilirubin. I muri i tētahi wā, ina mutu te roa o tō rātou oranga, ka pakaru ngā toto whero i roto i tō tātou tinana. Ko te wā tēnei e hangaia ai tēnei bilirubin. Ko te tikanga, me tukuna tēnei bilirubin mai i tō tātou ate me te au, ka tukuna mai i te tinana hei para. Heoi, kāore tēnei tukanga e tupu tika i roto i te tinana o te tangata e pāngia ana e te mate Dubin-Johnson. Nō reira, ka kohikohi te bilirubin i roto i te ate me te toto, ka puta ai ngā tohu pēnei i te jaundice . Ko te wā tēnei ka kōwhai te kiri me te mā o ngā kanohi.

Ko wai te mea tino pāngia e tēnei āhuatanga?

He mate ira te mate Dubin-Johnson, nō reira ka pā ki te tangata katoa, ahakoa te pakeke. Kia riro mai ai i a koe te mate, me tuku iho e ō mātua te ira ki a koe. Ka kiia tēnei he tukunga iho autosomal recessive . Hei tauira, ki te riro mai i a koe te ira mai i tētahi o ō mātua anake, kāore koe e whakaatu i ngā tohu, engari ka noho koe hei kaikawe i te ira. Ko te tikanga ka taea e koe te tuku i te ira ki ō tamariki.

E hia te auau o tēnei āhuatanga?

Kāore he tatauranga tika mō te auau o tēnei mate, engari he nui ake te kitea i roto i ngā tāngata e noho ana i ngā whenua pēnei i a Īrāna, Irāki, Moroko, me Hapani. E kiia ana tata ki te kotahi i roto i te 1,300 tāngata i aua whenua ka pāngia e tēnei mate.

He aha te pānga o te mate Dubin-Johnson ki tōku tinana?

Ko te mate Dubin-Johnson te take o te kohikohinga o te matū kōwhai bilirubin i roto i tō ate. Koinei te mea e āhua kōwhai ai tō kiri me te mā o ō kanohi. I ētahi wā, ina noho koe i roto i te whare, ā, i raro i te mārama iti, kāore pea koe e kite i tēnei kōwhai. Heoi, i roto i tētahi wāhi e mārama ana, pērā i te rā, ka kitea nuitia tēnei kōwhai. He maha ngā wā, ko te mea tuatahi ka kitea e koe mō tēnei kōwhai ko te mata.Kātahi ka horapa ki ētahi atu wāhanga o te tinana, pērā i te uma me te puku. Ina titiro koe ki te whakaata, ki te whakatuwhera koe i tō waha ka titiro ki raro i tō arero, ka kite koe kua kōwhai kē hoki i reira.

He aha ngā tohu o tēnei?

Ko te nuinga o te hunga kua tāpaetia ki te mate Dubin-Johnson, ko ngā tohu matua ko te jaundice, e puta mai ana i te kohikohinga o te bilirubin i roto i te ate. Ko te tikanga tēnei:

• Te kōwhai o tō kiri me te mā o ō kanohi.
• He panoni i te tae o tō mimi (ka huri ki te kōwhai pouri, ki te parauri rānei).

I ētahi wā, ina pāngia te tinana e te ahotea, hei tauira, ina pāngia koe e tētahi atu mate, i te wā e hapu ana, kei te whakamahi rānei koe i ngā pire ārai whānau (ngā ārai hapūtanga), ka piki ake pea tēnei tae kōwhai.

Haunga ēnei, tera pea ka puta ētahi atu tohu iti, engari kāore i te tino kino:

• Ko te ngenge he `(Fatigue)`.
• He mamae iti i te puku o raro (mamae puku).

Ko te mea nui, he mate pai te mate Dubin-Johnson. Arā, kāore e pā kino nui ki tō oranga.

Ki te whakahaere koe i ētahi whakamātautau, ka kite pea koe i ēnei mea:

• He puranga matū kei roto i tō ate, ā, ka āhua mangu (ka tirohia tēnei mā te tango i tētahi wahi kiko iti mai i te ate - ka kiia ko te 'Liver Biopsy ').
• Tērā pea ka paku rahi te ate ( Hepatomegaly ).

He aha te take o te mate Dubin-Johnson?

Ko te tino take o te mate Dubin-Johnson he whakarerekētanga ira i roto i te ira `ABCC2`. Ko tēnei ira `ABCC2` te kawenga mō te hanga i tētahi pūmua hei āwhina i ō tātou pūtau ki te tango i ngā para. Ina koa, ka āwhina tēnei pūmua i ngā pūtau ate ki te tango i te bilirubin (te matū kōwhai i toe mai i te pakaru o ngā toto toto whero) me te whakaputa hei au (he wai e āwhina ana ki te nakunaku kai).

Nō reira, ki te pāngia koe e te mate Dubin-Johnson, kāore e taea e tō tinana te tango tika i tēnei para e kiia nei ko te bilirubin mai i ō pūtau. Nō reira, ka kohikohi ngā mea pēnei i te bilirubin i roto i tō tinana (e kiia ana tēnei ko te hyperbilirubinemia ). Koia te take ka puta ai ngā tohu pēnei i te jaundice.

Me pēhea te tautuhi i te mate Dubin-Johnson?

Ka tirohia koe e tō tākuta, ka pātai atu mō ō tohumate, ā, ka kimihia mēnā kua pāngia tētahi o tō whānau e ngā āhuatanga ōrite i mua (hītori hauora whānau).

Kātahi ka tonoa e rātou ētahi atu whakamātautau hei whakaū i te mate. Kei roto pea i ēnei:

• Ngā whakamātautau whakaahua (hei tauira , he hihi-X , he matawai ultrasound ) hei tirotiro i tō ate.
• Ngā whakamātautau toto (ina koa te whakamātautau bilirubin )kotahi).
• Ngā whakamātautau mimi .
• He whakamātautau pea ka tangohia he wāhanga iti o te ate ( 'Liver Biopsy ').

Mena ka whakaatuhia e te whakamātautau bilirubin he nui rawa te taumata bilirubin i roto i tō toto, ko te tikanga he mate tōu e kiia nei ko te hyperbilirubinemia (he nui te bilirubin i roto i te toto). Mena ka mau tonu ō tohu, ka tono pea tō tākuta i tētahi whakamātautau toto ira hei kimi i te ira e puta ai ō tohu. Koinei anake te huarahi hei whakaū kei a koe te mate Dubin-Johnson.

He aha ngā maimoatanga mō tēnei?

Ko te rongo pai, ko te nuinga o te hunga kua kitea he mate Dubin-Johnson kāore e hiahiatia he maimoatanga. Nā te mea ehara i te mate kino. Heoi, ki te hiahiatia he maimoatanga, ko te tikanga he mate, he tukanga rānei e piki ake ai ō taumata bilirubin. Hei tauira, ki te pāngia koe e te makariri, ka kī atu pea tō tākuta kia inu koe i te nui o ngā wai me te okioki. Ki te mea rānei kei te kino haere ō tohumate i tētahi rongoā e tangohia ana e koe, ka kī atu pea tō tākuta kia mutu te tango i taua rongoā.

He aha ngā mea ka kino ake ai ngā tohu o te mate Dubin-Johnson?

Ka roa pea ngā tohumate o te jaundice i puta mai i te mate Dubin-Johnson mō te wā katoa. Heoi anō, ka kino ake pea ēnei tohumate mēnā:

• Ki te inu waipiro koe.
• Mena kei te tango koe i ngā pire ārai whānau.
• Mena he mate pāwera.
• Mena kei te hapu koe.

Ki te mea kei te kino haere ō tohumate, kōrero ki tō tākuta mō ngā kōwhiringa maimoatanga hei āwhina i a koe ki te kimi i te whakaoranga.

Ka taea te ārai i te mate Dubin-Johnson?

Nā te mea he mate ira tēnei, kāore e taea te ārai i te whanaketanga o te mate Dubin-Johnson. Heoi, ki te mea kei te whakaaro koe kia whānau he tamaiti, ā, e hiahia ana koe ki te mōhio ki te mōrearea o te pāngia o tāu tamaiti e tēnei mate ira, ka taea e koe te kōrero ki tō tākuta mō te whakamātautau ira , te tohutohu ira rānei.

Mena kei a au te mate Dubin-Johnson, he aha taku e tumanako ai?

He tino pai te tirohanga mō te hunga kua tāpaetia ki te mate Dubin-Johnson. Kāore he rongoā, ā, kāore e hiahiatia he maimoatanga, ā, ka whakahaeretia ngā tohu. Ko te mea nui, kāore te mate e pā ki te roanga o te oranga o te tangata.

Kia pēhea te wā me toro atu ahau ki taku tākuta?

Ki te kino haere ngā tohu o te mate Dubin-Johnson, ina koa mēnā he rite ngā tohu ki te rewharewha ki te jaundice, me toro atu ki tō tākuta. Hei tauira:

• Mamae puku .
• Kirika .
• Te ngenge .
• Whakapairuaki, ruaki rānei .

He aha ngā pātai me pātai atu e au ki taku tākuta?

Ka taea e koe te pātai atu ki tō tākuta i ēnei pātai:

• Me rongoā rānei aku tohumate?
• Ka riro mai rānei i taku tamaiti tēnei āhuatanga?
• Me aha ahau mēnā kei te pāngia ahau e te mate nā aku tohumate?

He aha te rerekētanga i waenga i te mate Dubin-Johnson me te mate Rotor?

He mate ira te mate Dubin-Johnson me te mate Rotor . He rite tonu ngā tohu o ēnei mate e rua, pērā i te jaundice. Heoi, ko te rerekētanga matua i waenga i ngā mate e rua ko tō rāua take.

Ko te mate Dubin-Johnson i puta mai i te whakarerekētanga o te ira 'ABCC2'. Heoi, ko te mate Rotor i puta mai i te whakarerekētanga o te ira 'SLCO1B1' me te 'SLCO1B3' .

Ko tētahi atu mea nui hei mōhio ko te pānga nui o te Rotor Syndrome ki te āhua o te tinana o te tangata e whakahaere ana i ētahi rongoā. Nō reira, ki te pāngia koe, tāu tamaiti rānei e te Rotor Syndrome, he mea tino nui kia whakamōhio atu koe ki tō tākuta i mua i te tuku i ētahi rongoā.

Hei tāpiritanga, kāore te Rotor Syndrome e whakapōrearea i te ate. Heoi, he mangu te āhua o te ate o te hunga e pangia ana e te Dubin-Johnson Syndrome.

He mea noa te āwangawanga ina huri kōwhai te kiri o tō pēpi, o tō kiri rānei. Ahakoa he mea noa te jaundice i roto i ngā pēpi hou, ko te jaundice i puta mai i te mate Dubin-Johnson he mate pumau, mō te wā roa.

Hei whakamutunga, ngā mea hei maumahara (Karere hei tango ki te kāinga)

Nā, kua mōhio nui koe inaianei mō te mate Dubin-Johnson. Kaua e manukanuka, ehara i te mate kino. Mā tō tākuta e whakamārama te maimoatanga e hiahiatia ana hei whakaiti i te kōwhai o ō kanohi me tō kiri, mēnā rānei ka puta mai ētahi atu tohu. Ko te mea nui ko te kōrero ki tō tākuta mō ō tohu i ia wā, i ia wā, kia mōhio ai kei te ora koe. Ka taea e koe te noho noa, te noho harikoa me tēnei mate.

` Te mate Dubin-Johnson, te kirika kōwhai, te ate, te bilirubin, ngā mate ira, te kōwhai o te kiri, te jaundice