Ngā mea e hiahia ana koe kia mōhio mō ngā MAOI (Monoamine Oxidase Inhibitors)

Kua tohua e tō tākuta tētahi momo rongoā e kiia nei ko te MAOI? Kua rongo rānei koe mō tēnei rongoā i tētahi wāhi, ā, kei te hiahia koe ki te mōhio he aha tonu? Ko ngā MAOI he momo rongoā e hoatu ana hei rongoā i ngā mate hinengaro pēnei i te pouri. Heoi, kāore ngā tākuta e tūtohu pinepine ana i ēnei rā. He maha ngā take motuhake mō tēnei. Me kōrero tātou mō tēnei mai i te tīmatanga, he tino māmā noa iho, i roto i te huarahi e mārama ai koe.

He aha te momo rongoā he MAOI?

Ki te whakarāpopototanga, ko ngā MAOI (Monoamine Oxidase Inhibitors) te momo rongoā tuatahi i kitea hei rongoā i te pouri. Heoi, me tino tupato koe ki tāu e kai ana i a rātou e whakamahi ana. Waihoki, nā te mea he pānga taha me ngā raruraru ki ētahi atu rongoā, he maha ngā tākuta e taunaki ana i ēnei hei huarahi whakamutunga, ina kore e whai hua ētahi atu momo rongoā ārai pouri.

Arā, ki te mea kua hoatu he rongoā hou ake ki a koe pēnei i ngā SSRI, ā, kāore anō ō tohu kia pai ake, ka whakaarohia pea e tō tākuta he MAOI hei mahi e whai ake nei.

He aha ngā momo MAOI matua e whakamahia ana i te ao?

He maha ngā momo MAOI matua e whakamahia ana i tēnei wā. He rerekē pea te kitea o ēnei momo katoa i tō tātou whenua, engari he mea pai kia mōhio ki ēnei ingoa.

• Isocarboxazid (Marplan®)
• Phenelzine (Nardil®)
• Selegiline (Emsam®)
• Tranylcypromine (Parnate®)

He aha ngā āhuatanga e tohua ai ngā rongoā MAOI?

Ahakoa e tohua ana tēnei rongoā mō te pouri, ka whakamahia anō hoki mō ētahi atu āhuatanga hauora hinengaro.

Ngā whakamahinga kua whakaaetia ā-mana

Koinei ngā wā kua whakaaetia e ngā mana whakahaere e tika ana tēnei rongoā hei rongoā mō ēnei mate.

• Mate Pouri Nui: Kua whakaaetia te Isocarboxazid me te Tranylcypromine mō tēnei āhuatanga.
• Ngā mate e kore e taea te rongoā: Ka whakamahia te Phenelzine hei rongoā i te pouri, te mate mataku, me te mate manukanuka pāpori kāore e pai ki ētahi atu maimoatanga.
• Te Mate a Parkinson: He rongoā te Selegiline e whakamahia ana hei rongoā i te pouri, ā, e whakamahia ana hoki hei rongoā tāpiri me ētahi atu rongoā mō te mate a Parkinson.

Ngā whakamahinga "kāore i te tapanga"

I ētahi wā, ka tohua pea tēnei rongoā e te tākuta i runga i ōna mōhiotanga hauora me ōna wheako mō tētahi āhuatanga kāore anō kia whakaaetia mana. Ka kiia tēnei ko te whakamahinga "kore-tohu". Hei tauira:

• I ētahi wā ka tohua he rongoā e kīia ana ko te tranylcypromine mō te manukanuka pāpori me te mate mataku ātete ki te rongoā.
• He wā anō ka tohua te rongoā Selegiline mō te mate aro nui kore mahi (ADHD).

He pēhea te mahi a tēnei rongoā i roto i te tinana?

He tino māmā noa iho tēnei ki te mārama. Whakaarohia kei roto i ō tātou roro ngā matū e whakahaere ana i ngā mea pēnei i tō tātou wairua, tō tātou harikoa, me tō tātou aro. Ka kiia ēnei he neurotransmitters . He rite ēnei ki ngā karere iti e kawe ana i ngā karere i roto i te roro.

Ināianei, kei roto i tō tātou tinana tētahi whākōkī e kiia nei ko te "Monoamine Oxidase." Ko te mahi a tēnei whākōkī he wawahi me te tango i aua karere (neurotransmitters) i muri i te whakamahinga.

Tērā pea he iti noa iho ngā taumata o ēnei karere i roto i te roro o te tangata e pāngia ana e te pouri. Ko tā te rongoā MAOI he aukati (whakakore) i te mahi a taua whākōkī 'horoi' mō te wā poto. Ka aha rā?

He maha ngā neurotransmitters nui i roto i te roro ka noho roa ki roto i te roro me te kore e pakaru, ko te tikanga ka piki ake ō rātou taumata.

Ko ngā neurotransmitters matua i whakanuia e ngā MAOI ko:

• Serotonin: He mea tino nui mō te wairua, te moe, te hiahia kai, me te whanonga pāpori.
• Norepinephrine: He mea nui mō te mataara, te arotahi, me te mahi.
• Dopamine: E pā ana ki te ahuareka, te makona, me te aro.
• Tyramine: He momo neurotransmitter anō hoki tēnei. Engari ko tana mahi matua he āwhina i te whakahaere i te toto toto. Koinei te take matua me tupato koe ki tāu e kai ana ina tango ana i te MAOI. Ka kōrerohia e tātou tēnei i roto i ētahi atu kōrero.

He aha te rerekētanga i waenga i ngā MAOI me ngā SSRI?

Ko ngā SSRI (Selective Serotonin Reuptake Inhibitors) tētahi atu momo rongoā e whakamahia ana hei rongoā i te pouri. Kua rongo pea koe i ngā ingoa pēnei i a Prozac me Sertraline. Ahakoa he rongoā e rua e whakamahia ana hei rongoā i te pouri, he rerekē te mahi a rāua.

• SSRI: He rite ēnei ki ngā kaipupuhi. Ka aro noa rātou ki te neurotransmitter serotonin , ka whakapiki ake i ōna taumata.
• MAOI: He rite ēnei ki te pū. Ka pāngia e rātou ētahi neurotransmitters (serotonin, norepinephrine, dopamine) i te wā kotahi.

Nā te mea he iti noa ngā pānga taha o ngā rongoā SSRI, ā, kāore he ture motuhake mō te kai me te inu, ko te tikanga ka tūtohu tuatahi ngā tākuta i ngā rongoā SSRI.

He aha ngā pānga taha noa o ngā MAOI?

Pērā i ngā rongoā katoa, ka pāngia pea tēnei e ngā pānga taha. Engari kāore e pāngia te katoa. Tērā pea ka pāngia ētahi e te kotahi, e rua rānei, ā, ko ētahi kāore pea e pāngia e te mamae. Ki te pāngia koe e tētahi mamae hou i muri i te tīmatanga o tēnei rongoā, kōrero ki tō tākuta mō tēnei.

Ngā mōrearea nui e pā ana ki te whakamahi i ngā MAOI!

Me tino mōhio koe ki tēnei wāhanga. He rongoā ngā MAOI me tino tupato ki te whakamahi.

1. Te pikinga ake o ngā whakaaro whakamomori

Tērā pea ka piki ake ngā whakaaro, ngā whanonga rānei e pā ana ki te whakamomori, inā koa i roto i ngā taiohi kei raro iho i te 25 tau te pakeke, ina tīmatahia te rongoā, ina whakarerekētia rānei te horopeta.

2. Te Mate Serotonin

He āhuatanga onge tēnei, engari he mate pea ka mate . Ka puta ina tino teitei rawa ngā taumata serotonin i roto i te tinana. Ka piki ake tēnei mōrearea mēnā ka tangohia e koe he MAOI i a koe e tango ana i ētahi atu rongoā e whakanui ana i ngā taumata serotonin (hei tauira, ētahi atu rongoā ārai pouri, ētahi rongoā maremare, me ngā rongoā whakamamae mamae).

Nō reira, i mua i tō tīmatanga ki te tango i te MAOI, me kōrero koe ki tō tākuta mō ngā rongoā katoa e tangohia ana e koe i tēnei wā (tae atu ki ngā huaora me ngā rongoā tuku iho).

3. Te Mate Whakamutu i te Whakahaunga Pōuri

Ki te neke atu i te 6 wiki te roa o te tango i te MAOI, kātahi ka mutu ohorere, tera pea ka pāngia koe e ngā tohumate tango. Ehara tēnei i te waranga, engari he huarahi e tauhohe ai te tinana ki te rongoā ina taunga haere ki a ia.

Ngā Āhuatanga:

• Mamae tinana, ngenge, me te werawera, me te mea kei te kirika koe
• Te kore moe
• Whakapairuaki
• Pōuriuri
• Te āhua nei kei te haere te hiko i roto i tō tinana
• Manukanuka, riri

4. Tauhohenga mōrearea ki te kai (Tauhohenga Tyramine)

Koinei te mōrearea tino nui me te mōrearea o ngā MAOI.

E ai ki tā tātou i kōrero ai i mua ake nei, ka āraihia e ngā rongoā MAOI te whākōkī e wawahi ana i tētahi matū e kiia nei ko te tyramine. He mea noa te kitea o te tyramine i roto i ētahi kai e kainga ana e tātou. Mō te tangata kāore e tango ana i te rongoā, ka ngawari te wawahi a te tinana i tēnei tyramine, ā, ka whakakorea atu.

Engari ki te kai tetahi i te kai MAOI i te kai he nui te tyramine, kāore e taea e te tinana te wawahi. Kātahi ka piki te taumata o te tyramine i roto i te toto, ka piki ohorere te toto toto (hypertensive crisis) . He tino morearea tēnei. I ētahi wā onge, ka arahi pea tēnei ki te toto toto o te roro, tae atu ki te mate.

Ngā kai me 'tino' karo i te wā e tango ana i ngā MAOI!

Mena kei te tango koe i te MAOI, me karo rawa koe i ngā kai kei te rārangi i raro nei. Kōrero ki tō tākuta mō tēnei mō ētahi atu kōrero.

Ko te mea nui: Kainga te kai ina oti te tunu. Whakatōkia ngā toenga kai ki roto i te pouaka whakamātao, ā, kaua e whakamahana anō. I te pakeketanga o te kai, ka piki ake pea ngā taumata tyramine.

Kia pēhea te roa ka puta ai ngā pānga o te rongoā?

E rua ki te toru wiki te roa ka puta te pānga katoa o te rongoā. Ki te kore koe e kite i tētahi whakapainga i roto i ō tohumate i taua wā, kōrero ki tō tākuta.

Āhea koe me waea atu ki tō tākuta?

Mena kei te tango koe i te MAOI, me toro atu koe ki tō tākuta i ia wā, kia kite ai mēnā kei te mahi te rongoā, ā, mēnā he raruraru kei a koe. Hei tāpiri, me kōrero ki tō tākuta mō ēnei mea:

• Mena ka pāngia koe e ngā pānga taha.
• Ki te kore ō tohu e pai ake, e kino rānei.
• Ki te mea kei te whakaaro koe me mutu te tango i te rongoā.