Ka pāngia tātou katoa e ngā panonitanga iti me ngā mamae o te tinana i ētahi wā, tika? He puku iti pea i te kaki, he ngenge noa iho rānei, he matewai tonu rānei. Ahakoa ehara i te mea hei āwangawanga te nuinga o ēnei mea, i ētahi wā onge, koinei pea ngā tohu matua o tētahi mate hauora. I tēnei rā ka kōrero tātou mō tētahi momo mate pukupuku he onge noa iho, engari he mea tino nui kia mōhio tātou katoa. Koia te mate pukupuku e puta ana i roto i ngā repe parathyroid, e kiia ana i roto i te rongoā ko te mate pukupuku parathyroid , ko te '(Parathyroid Carcinoma)' rānei.
He aha te Matepukupuku Parathyroid?
He kupu ngāwari noa iho, he momo matepukupuku tino onge te matepukupuku parathyroid e puta ana i roto i ngā kiko o ō repe parathyroid. Kei muri i te repe tairoi āhua pūrerehua i mua o tō kaki ō repe parathyroid.
Kāore te mate pukupuku parathyroid e whakarōpūtia kia whā ngā wāhanga (te "pūnaha whakaingoa wāhanga-whā") pērā i ētahi atu momo mate pukupuku. Engari, ka wehea e ngā tākuta te mate pukupuku kia toru ngā momo matua:
- Ā-rohe: Ko te tikanga o tēnei ko te mate pukupuku kei roto noa i tō repe parathyroid. I ētahi wā kua horapa noa ki ngā kiko e karapoti ana. Ko te tikanga o tēnei ko te mate pukupuku kei te noho tonu ki tētahi wāhi.
- Metastatic: Koinei te wā kua horapa te mate pukupuku ki ētahi atu wāhanga o tō tinana, pērā i ngā pona lymph, te ate, ngā pukahukahu, ngā wheua, te pancreas rānei. I waenga i te 10% me te 30% o te hunga whai mate pukupuku parathyroid ka horapa te mate pukupuku (metastatic) i te wā i tautuhia ai. Ko ngā wāhi tino kitea ko ngā pukahukahu, ngā wheua, te ate rānei.
- Te hokinga mai: Koinei te wā ka hoki mai anō te mate pukupuku i muri i te maimoatanga tuatahi – i muri i te tangohanga o te repe mate pukupuku mā te pokanga. Neke atu i te haurua o te hunga whai mate pukupuku parathyroid ka pāngia e tēnei momo mate pukupuku. I te nuinga o te wā ka hoki mai te mate pukupuku i roto i ngā tau e rua ki te rima i muri i te pokanga tuatahi. Heoi, i ētahi wā ka hoki mai anō tae noa ki te 20 tau.
He aha ēnei repe parathyroid?
E whā ngā repe parathyroid o te nuinga o tātou, he rite te rahi ki te pī. E ai ki te kōrero i mua ake nei, kei muri i te repe tairoiti ēnei. Pērā i te repe tairoiti, he wāhanga ngā repe parathyroid o tō pūnaha endocrine. I ētahi wā, ka kitea ēnei repe parathyroid i te taha o tō korokoro, i roto rānei i tō uma. Ka kiia tēnei he ectopic.E kiia ana ngā repe parathyroid he repe parathyroid, arā, kāore rātou i te wāhi e tika ana kia noho ai rātou.
Ko te mahi matua a ō repe parathyroid he whakahaere i te nui o te konupūmā i roto i ō toto mā te whakaputa i te homoni parathyroid (PTH) . I ētahi wā, ka tīmata tētahi, neke atu rānei o ō repe parathyroid ki te whakaputa i te nui rawa o tēnei homoni parathyroid (PTH). Ka kiia tēnei āhuatanga ko te Hyperparathyroidism Tuatahi (pHPT) . Ina nui rawa te PTH e whakaputaina ana, ka piki ake te taumata konupūmā i roto i ō toto. Ka kiia tēnei āhuatanga ko te hypercalcemia .
He aha te rerekētanga i waenga i te mate pukupuku parathyroid me te adenoma parathyroid?
He tipu pai, ehara i te matepukupuku te adenoma parathyroid i roto i te repe parathyroid. Heoi, ko te matepukupuku parathyroid te whanaketanga o ngā pūtau kino, ehara i te matepukupuku i roto i tō kiko parathyroid. O ngā mate e pā ana ki ngā repe parathyroid, he nui ake te kitea o te adenoma parathyroid i te matepukupuku parathyroid.
Engari koinei te mea nui: I roto i ēnei āhuatanga e rua, arā, te mate pukupuku parathyroid me te adenoma parathyroid, ka kaha rawa te mahi a tō repe parathyroid, ā, ka nui rawa te homoni parathyroid (PTH). Kātahi, e ai ki te kōrero i mua ake nei, ka puta te hypercalcemia. Ka kino pea tēnei hypercalcemia ki tō tinana me tō hauora. Nō reira, ko te maimoatanga tino noa mō te mate pukupuku parathyroid, me ngā adenoma parathyroid, ko te tango pokanga i te repe parathyroid kaha rawa.
Ahakoa mō ngā tākuta, he uaua ki te kī tonu mēnā he adenoma parathyroid, he carcinoma parathyroid rānei. Nā te mea he rite te āhua o ngā pūtau o ngā mea e rua, i muri i te tangohanga o te repe parathyroid e kaha rawa ana te mahi mā te pokanga, me whai whakamātautau anō hei whakaū mēnā he adenoma, he carcinoma rānei.
He aha te hypercalcemia? He aha tōna hononga ki te mate pukupuku parathyroid?
Ko te hypercalcemia he wā e teitei ake ai ngā taumata konupūmā o roto i tō toto i te mea noa. He maha ngā wā ka pāngia te hunga whai mate pukupuku parathyroid e te hypercalcemia. Nā te mea ka nui rawa te mahi a tō repe parathyroid e te mate pukupuku, ā, ka nui rawa te homoni parathyroid (PTH). Ka whakahaere te homoni parathyroid (PTH) i te nui o te konupūmā i roto i tō toto. Nō reira, ki te nui rawa te homoni parathyroid (PTH), ka piki ake ngā taumata konupūmā o roto i tō toto.
Ka pā kino pea te hypercalcemia ki tō hauora me tō tinana. Nō reira, he mea tino nui te rongoā i te hypercalcemia i puta mai i te mate pukupuku parathyroid me te mate pukupuku tonu.
He rerekē ngā momo matepukupuku parathyroid?
Āe, e rua ngā momo matua o te mate pukupuku parathyroid.
1. Te momo tino noa: I tēnei wā, ka meinga e ngā pūtau matepukupuku tō repe parathyroid kia nui rawa te homoni parathyroid (PTH) ka tukuna ki roto i te toto. Ka piki ake te taumata konupūmā i roto i tō toto.
2. Te mate pukupuku parathyroid kore mahi: Ka kiia hoki tēnei ko te "mate pukupuku parathyroid kore-huna". He rerekē tēnei i ngā momo kē atu. Nā te mea, kāore he taumata teitei o te homoni parathyroid (PTH) me te konupūmā i roto i te toto o te hunga whai mate pukupuku parathyroid. He tino onge tēnei momo, e puta ana i raro iho i te 10% o ngā tūroro mate pukupuku parathyroid.
Kia kitea te mate pukupuku parathyroid, ka mahia ētahi atu whakamātautau hei whakatau mēnā he rohe , he horapa , he hokihoki rānei. E ai ki te kōrero i mua ake nei, kāore te whakarōpūtanga wāhanga-whā e whakamahia ana mō ētahi atu mate pukupuku e whakamahia ana mō tēnei.
Ko wai te hunga ka nui ake te tūponotanga ki te pāngia e te mate pukupuku parathyroid?
He ōrite te pānga o tēnei mate pukupuku ki ngā wāhine me ngā tāne. He maha ngā wā ka kitea tēnei mate i roto i te hunga neke atu i te 30 tau te pakeke .
He pēhea te noa o tēnei mate?
He mate tino onge te mate pukupuku parathyroid. Whakaarohia, 0.005% noa iho o ngā mate pukupuku katoa e pā ana ki tēnei mate. Waihoki, kei waenganui i te 0.5% me te 1% o ngā mate katoa e pā ana ki te repe parathyroid te mate pukupuku parathyroid. Nō reira, he tino onge tēnei.
He aha ngā take o te matepukupuku parathyroid?
Ina hoki, kāore anō kia kitea he tino pūtake o te mate pukupuku parathyroid.
Heoi, ko ngā āhuatanga ira onge e whai ake nei (arā, he mea tuku iho i te whānau) e kiia ana he take mōrearea mō tēnei mate pukupuku:
- He maha ngā momo neoplasia endocrine I (MEN1)
- Te hyperparathyroidism motuhake whānau (FIHP)
- Te mate pukupuku kauae o te hyperparathyroidism
Hei tāpiri, mēnā kua whiwhi koe i te rongoā irahiko ki tō mahunga, ki tō kaki rānei i mua, ka taea hoki e ia te whakanui ake i tō tupono ki te whakawhanake i te mate pukupuku parathyroid.
He aha ngā tohu o te matepukupuku parathyroid?
I te nuinga o te wā, ko ngā tohu o te mate pukupuku parathyroid ko ngā tohu o te hypercalcemia e puta mai ana. Ko ngā tohu me ngā tohu o te hypercalcemia ko:
- Te hiahia kia mimi pinepine atu i te tikanga (te mimi pinepine)
- Te matewai nui atu i te tikanga
- Whakapairuaki me te ruaki
- Pērā i te tikangaKāore e hiakai ana
- Te kōroke
- Tino ngenge te ngenge
- Te āhua nei kei te pouri koe
- Te warewaretanga, te ngaronga rānei o te mahara
- Mamae uaua, ngoikore, me/ranei te totitoti
Ko ētahi atu tohu pea o te mate pukupuku parathyroid:
- He puku kei te kaki
- Ngā huringa reo, te pāorooro rānei
- Te uaua ki te horomi i te kai
Mena kei a koe tētahi, ētahi rānei o ēnei tohu, kaua e wehi ki te whakaaro he mate pukupuku parathyroid tēnei. Ka kitea anō hoki ēnei tohu i roto i ētahi atu āhuatanga. Heoi, ki te mau tonu tēnei āhuatanga, he pai ake te toro atu ki tētahi tākuta mō ētahi tohutohu.
Me pēhea te tātaritanga o te mate pukupuku parathyroid?
He uaua pea te tautuhi i te mate pukupuku parathyroid i ētahi wā. Ko tētahi take he rite tonu te āhua o ngā pūtau o te adenoma parathyroid kore-mate pukupuku me ērā o te mate pukupuku parathyroid.
He maha ngā wā ka kitea te mate pukupuku parathyroid i muri i te tangohanga o tō repe parathyroid rerekē, tino kaha rawa (he `parathyroidectomy`), ā, ka tirotirohia anō te kiko. I ētahi wā, ka kitea e te taote pokanga te mate pukupuku parathyroid i te wā e pokanga ana.
He aha ngā whakamātautau e mahia ana hei tautuhi mate?
E ai ki te kōrero i mua ake nei, he maha ngā wā ka kitea te mate pukupuku parathyroid i muri i te tautuhi i te hyperparathyroidism tuatahi , ā, ka tangohia te repe parathyroid rerekē, tino kaha rawa atu mā te pokanga. I ētahi wā, ka taea e te taote pokanga te tautuhi i te mate pukupuku parathyroid i te wā o te pokanga.
I mua i tō pokanga hei tango i tō repe parathyroid hyperactive, ka whai pea koe i ngā whakamātautau penei:
- Whakamātautau konupūmā toto
- Whakamātautau PTH toto
- Matawai parathyroid - He matawai sestamibi irahiko me/ranei he matawai CT tēnei i te nuinga o te wā.
Mena kua tāpaetia koe he mate pukupuku parathyroid, ka tono pea tō tākuta i ngā whakamātautau whakaahua pēnei i ēnei hei tirotiro mēnā kua horapa te mate pukupuku (metastasized) ki ētahi atu wāhanga o tō tinana:
- Matawai CT (matawai tomografi rorohiko): Ka whakamahia e te matawai CT ngā hihi-X me te rorohiko hei hanga i ngā whakaahua toru-ahu (3D) o tō tinana.
- Matawai MRI (MRI - whakaahua aukume):Ka whakamahia e te matawai MRI tētahi aukume nui, ngā ngaru reo irirangi, me te rorohiko hei hanga whakaahua taipitopito o tō tinana. Kāore e whakamahia ngā hihi-X (irahiko).
He aha ngā maimoatanga mō te mate pukupuku parathyroid?
Ko te huarahi maimoatanga matua mō te matepukupuku parathyroid ko te tango pokanga i te repe parathyroid matepukupuku ('en bloc resection'). Mena kua horapa (metastasized) te matepukupuku parathyroid, me tango pea e tō taote pokanga te kiko huri noa i tō repe parathyroid, te kiko matepukupuku rānei mai i ētahi atu wāhanga o tō tinana.
Ka taea te whakamahi i ngā tikanga pokanga e whai ake nei mō te mate pukupuku parathyroid:
- Te tango ā-pū: I roto i tēnei tikanga, ka tangohia e te taote pokanga tō repe parathyroid katoa me te kāpū e karapoti ana. I ētahi wā, ka tangohia pea e rātou te haurua o te repe tairoiti i te taha kotahi me te repe parathyroid matepukupuku, me ngā kiko e karapoti ana, ngā uaua, me ngā io.
- Te tango i te pukupuku: I tēnei tikanga, ka tangohia e te taote pokanga te nuinga o te pukupuku e taea ana. Tērā pea kāore ētahi pukupuku e tangohia katoatia.
- Metastasectomy: I tēnei mahi, ka tangohia e te taote pokanga tetahi mate pukupuku kua horapa (metastasized) ki ētahi atu kiko me/ngā okana rānei o tō tinana, hei tauira, ngā pukahukahu.
Ka whiwhi ahau i te chemotherapy, i te radiation therapy rānei?
Kāore te rongoā matū me te rongoā irahiko e whakamahia ana hei rongoā i te mate pukupuku parathyroid. Mā tō tākuta e whakatau mēnā he kōwhiringa tika te rongoā matū me/ranei te rongoā irahiko māu.
He rongoā anō kei te wātea mō te mate pukupuku parathyroid?
I tēnei wā, kāore he rongoā motuhake mō te mate pukupuku parathyroid. He maha ngā tāngata e pāngia ana e te mate pukupuku parathyroid ka puta ngā tohu o te hypercalcemia. Nā te mea he kino te hypercalcemia, ka tohua pea e tō tākuta tētahi, ētahi rānei o ngā rongoā hypercalcemia e whai ake nei:
- Cinacalcet (Cinacalcet - Sensipar®)
- Ngā Bisphosphonates
- Denosumab (Denosumab - XGEVA®)
Mena he nui ngā tohu o te hypercalcemia kei a koe, ka tūtohu pea tō tākuta kia haria tonutia koe ki te hōhipera, kia tīmata ai te werohanga wai ā-uaua (IV) me ētahi atu maimoatanga.
Ka taea e taku mate pukupuku parathyroid te hoki mai?
Ae, neke atu i te haurua o te hunga kua tāpaetia he mate pukupuku parathyroid ka pāngia anō e te mate pukupuku.I te nuinga o te wā ka hoki mai te mate pukupuku i roto i ētahi tau – i waenganui i te rua me te rima tau. Engari i ētahi wā, ka pā mai pea i ngā tekau tau (20 tau, neke atu rānei) i muri i tō tātaritanga tuatahi me tō maimoatanga.
Ka taea e tēnei mate pukupuku te horapa (metastasize) ki ētahi atu wāhanga o te tinana?
Ae, ka taea e te mate pukupuku parathyroid te horapa (metastasize) ki ētahi atu wāhanga o tō tinana. I waenga i te 10% me te 30% o te hunga whai mate pukupuku parathyroid kua horapa kē te mate pukupuku (metastatic) i te wā i kitea ai. I ēnei wā, ka horapa te mate pukupuku ki ō pukahukahu, wheua, ate rānei. Heoi, ka taea hoki te horapa ki ō kōpū lymph, ki tō pancreas rānei.
He aha te āhua o te mate pukupuku parathyroid?
Ko te matapae mō te mate pukupuku parathyroid e whakawhirinaki ana ki te oti o te pokanga hei tango i te repe parathyroid i te wā tuatahi ka kitea ai koe he mate, nā te mea he iti noa ngā kōwhiringa maimoatanga tuarua pēnei i te radiation therapy me te chemotherapy.
Mō te hunga whai mate pukupuku parathyroid kua tangohia katoatia te pūtau, ā, kāore he pānga kino, ko te ōrau oranga e 90% i roto i ngā tau e rima i muri i te pokanga tuatahi. Ko te ōrau oranga hoki e 67% i roto i ngā tau tekau i muri i te pokanga tuatahi.
Neke atu i te haurua o te hunga kua kitea he mate pukupuku parathyroid, ā, kua pokangahia hei tango i te repe, ka hoki anō te mate pukupuku. I ēnei wā, ka hoki mai te mate pukupuku i roto i ngā tau e rua ki te rima i muri i te pokanga tuatahi. Heoi, ka taea e ia te hoki mai i ngā tekau tau i muri mai.
Ka taea te ārai i te matepukupuku parathyroid?
Engari, kāore anō kia mōhiotia he huarahi hei ārai i te mate pukupuku parathyroid. Waihoki, kāore he huarahi hei whakaiti i te tūponotanga o te whakawhanake i tēnei mate. Mena kua pāngia tētahi o tō whānau e te mate repe parathyroid, he mea pai kia kōrero koe ki tō tākuta.
He aha ngā pātai me pātai atu e au ki taku tākuta?
Mena he mate pukupuku parathyroid tōu, me pātai atu pea koe ki tō tākuta i ēnei pātai:
- Kua horapa te mate pukupuku ki tua atu i taku repe parathyroid?
- He aha te maimoatanga pai rawa atu mō te mate pukupuku parathyroid?
- He aha ngā mōrearea me ngā pānga taha o te maimoatanga?
- Kei te tūpono tōku whānau ki te pāngia e te mate pukupuku parathyroid?
- Ka taea e au te pāngia anō e te mate pukupuku parathyroid?
- Kei te tūpono ahau ki te pāngia e ētahi atu momo mate pukupuku?
- He aha te tiaki whai muri ka hiahiatia e au i muri i te maimoatanga?
- Me mōhio ahau ki ngā tohu o ngā raruraru?
Hei whakamutunga, ngā mea hei maumahara
He mea whakamataku te kitea he mate pukupuku tōu. Engari kia maumahara,Kei konei tō tīma hauora hei āwhina i a koe, hei whakaatu hoki i te huarahi maimoatanga pai rawa atu. Ahakoa ko te pokanga anake te maimoatanga mō te mate pukupuku parathyroid i tēnei wā, kei te whakapai tonu te rangahau me ngā maimoatanga mate pukupuku. Tērā pea he whakamātautau haumanu ka taea e koe te whai wāhi atu. Nō reira, kaua e wehi ki te pātai ki tō tākuta mō tō mate pukupuku parathyroid. Me whakarite kia whakamāramahia ngā mea katoa i roto i te huarahi e mārama ana koe.
Matepukupuku Parathyroid , Ngā Repe Parathyroid, Hypercalcemia, Hormone Parathyroid, PTH, Ngā Tohumate Matepukupuku, Te Maimoatanga Matepukupuku, Te Pokanga
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