Kia ako tātou mō te Mate Zollinger-Ellison i roto i ngā kupu māmā noa iho.

Kua rongo kē koe i te mate Zollinger-Ellison ? He ingoa tauhou pea tēnei, engari he mate tēnei ka pā ki ō tātou whekau, ā, he mea hei āwangawanga mā tātou. Ka puta he mate puku kino me te mate korere mau tonu nā te nui rawa o te waikawa i roto i te puku. Nō reira, me kōrero taipitopito tātou mō tēnei i tēnei rā, e tika ana?

He aha rawa te mate Zollinger-Ellison?

Ki te kī ngāwari, ko te tino take o tēnei mate e kiia nei ko te Zollinger-Ellison Syndrome (ZES) he momo pukupuku iti e tupu ana i roto i tō tātou tinana, inā koa i roto i te pancreas, i te wāhanga o runga rānei o te whekau iti (duodenum). Ka kiia ēnei pukupuku he gastrinomas . He momo pukupuku neuroendocrine ēnei.

Titiro mai, ka puta he homoni e kiia nei ko te gastrin i roto i ēnei gastrinoma. Ko tēnei homoni gastrin te tohu i tō tātou puku kia "Āe, tīmata te hanga waikawa inaianei." Nō reira, ina nui rawa te homoni gastrin e puta mai ana i ēnei pukupuku, ka nui rawa hoki te waikawa e puta mai ana i te puku. Whakaarohia he rite ki te wai e turuturu ana i te wai, kāore e kati rawa, ka piki haere te waikawa o tō tātou puku, kāore e taea te whakahaere. Ko tēnei waikawa nui rawa te take o ngā raruraru pēnei i te mate puku me te reflux waikawa.

He āhua āwangawanga te mea he mate pukupuku pea te 60% o ēnei gastrinomas . Kaua e manukanuka, pērā i ngā mea katoa, he rongoā anō hoki mō tēnei. I ētahi wā ka karangahia tēnei āhuatanga e ngā tākuta ko te "pancreatic ulcerogenic tumor syndrome".

He aha ngā tohu o tēnei? He aha ō tātou kare ā-roto?

I ētahi wā, kāore pea he tohu e puta mai i te mate Zollinger-Ellison (ZES). Heoi, ina puta ngā tohu, ko ēnei pea:

• Te werawera, te mamae rānei o te puku: Tērā pea ka rongo koe i te werawera i roto i tō puku, i te mea rānei kei te kai tetahi mea i a koe. Nā te nui rawa o te waikawa tēnei.
• Te ruaki toto, te rere toto rānei i roto i te tūtae: Ka puta tēnei i te toto mai i ngā patunga i roto i ngā whekau (toto o te puku).
• Te ngenge me te ngoikore: E ai ki te kōrero i runga ake nei, nā te toto e ngaro ana, ka ngenge pea koe, ka ngoikore hoki nā te anemia.
• Ngā tūtae hinuhinu, mānu: Tērā pea ka kite ētahi tāngata i te panoni o ā rātou tūtae, he hinuhinu pea te kakano.
• Te ngaunga o te uma: Hei whakamārama tika, he kare e mura ana i roto i te uma nā te waikawa e piki ake ana i te korokoro.
• Pupuhi, koretake o te kai: Tērā pea ka tino kitea tēnei i muri i te kai i te kai momona.
• Kāore he reka o te kai.
• Whakapairuaki me te ruaki.
• Te hiroki noa iho, kāore he take.

Ko te kaha o ēnei tohu e whakawhirinaki ana ki te rahi me te maha o ngā gastrinomas. Ka nui ake te gastrin e puta mai i ngā pukupuku nui ake, ka nui ake te waikawa e puta mai i te puku. Ka kino ake pea ngā tohu o te mate pukupuku peptic.

Kia maumahara, i ētahi wā ka horapa atu ēnei pukupuku ki te ate, ka arahi ki te mate pukupuku ate. Mēnā ka tupu tēnā, ka puta pea ngā tohu pēnei i te mākūkū, te kōwhai o ngā kanohi mā, me te kōwhai o te kiri (jaundice).

He aha te take o tēnei āhuatanga? He aha ngā take?

I te nuinga o te wā, ka puta noa te mate Zollinger-Ellison (ZES), arā, he uaua ki te tohu i te tino take.

Heoi, tata ki te 25% o te hunga whai mate nei kua kitea he mate ira kei a rātou e kiia nei ko te MEN Type 1 (Multiple Endocrine Neoplasia Type 1) . Ko te MEN Type 1 he mate onge, he mate tuku iho, ka taea e ngā pukupuku te whanake i roto i ngā repe endocrine maha o te tinana.

He aha ngā raruraru ka puta mai i tēnei mate? Me manukanuka ahau?

Ae, ko te Zollinger-Ellison Syndrome (ZES) he mate ka mōrearea pea i ētahi wā . Hei tauira, ki te aukatihia e te gastrinoma te wāhanga o runga o te whekau iti (duodenum), ka pakaru. Ka horapa hoki ki te ate. Ka puta pea te toto nui o te puku nā te nui rawa o te waikawa o te puku.

Heoi, kaua e mataku ina rongo koe i ēnei mea. Mēnā ka kitea wawetia te mate, ā, ka rongoatia tika, ka taea te ārai i ēnei raruraru.

Me pēhea te tautuhi a ngā tākuta i tēnei mate? (Tautuhinga)

Mena kei a koe ēnei tohu, ka tirohia tuatahitia koe e te tākuta, ka pātai atu mō ō tohu, ā, mēnā kua pāngia tētahi o tō whānau e ēnei mate. Kātahi ka whakahaerehia pea e rātou ngā whakamātautau pēnei i:

• Ngā whakamātautau toto: Ka taea e ēnei te tirotiro mēnā he tiketike rawa ngā taumata o te homoni gastrin i roto i tō toto (hypergastrinemia).
• Ngā whakamātautau whakaahua: Tērā pea ka mahia he matawai CT , he matawai MRI rānei hei tirotiro mēnā he pukupuku gastrinoma kei roto i te repe taiaki, i te duodenum rānei.
• Whakamātautau waikawa puku: I tēnei whakamātautau, ka whakaurua e te tākuta he ngongo iti ki roto i te puku mā te ihu, mā te waha rānei, ka tangohia he tauira o te waikawa ki reira.

Mena ka kitea ngā pukupuku i roto i ēnei whakamātautau tuatahi, ka taea e te tākuta te mahi i ētahi atu whakamātautau:

• Endoscopy: I tēnei whakamātautau, ka whakauruhia he ngongo iti me te kāmera e piri ana mā te waha, ā, ka tirotirohia te esophagus, te puku, te wāhanga o runga o te whekau iti (duodenum), me te pancreas.
• Ultrasound endoscopic: He huinga tēnei o te ultrasound me te endoscopy. Ka taea e ia te whakaputa whakaahua mārama ake.
• ERCP (Endoscopic Retrograde Cholangiopancreatography): He matawai motuhake anō hoki tēnei. Ka tirohia ngā roto o ngā awaawa au me ngā awaawa repeure.
• Te tango i te ngira pai: Mena he pukupuku kei reira, ka whakamahia tēnei tikanga ki te tango i tētahi wāhanga iti o taua pukupuku ka whakamātautau mō ngā pūtau matepukupuku (koiora).

He aha ngā maimoatanga mō tēnei? (Maimoatanga)

Ko ngā kōwhiringa maimoatanga e whakawhirinaki ana ki te kaha o ō tohu me te mea he mate pukupuku te gastrinoma. E toru ngā momo maimoatanga matua:

1. Rongoā:

• Ko te rongoā matua e tohua ana ko ngā aukati papu proton (PPI) . Ko te mahi a ēnei rongoā mā te whakaiti i te nui o te waikawa e hangaia ana i roto i te puku. He māmā noa iho, ka whakahaere i te waikawa nui e hangaia ana.

2. Pokanga:

• Tērā pea ka tūtohu tō tākuta kia pokangahia hei tango i te pukupuku. He maha ngā momo pokanga:
• Duodenectomy: Ka tangohia te pukupuku mā te tapahi iti i te taha o runga o te whekau iti (duodenum).
• Te tango i te puku: Te tango i tētahi wāhanga, i te katoa rānei o te puku.
• Pokanga ate: Mēnā he pukupuku kei roto i te ate, ka tangohia.
• Te tango i te repe taiaki: Te tango i tētahi wāhanga, i te katoa rānei o te repe taiaki.
• Te tango i te puku: Mena he puku kei te pane o te repe taiaki, ko ēnā anake ka tangohia marietia.

3. Te rongoā matepukupuku:

• Mena he mate pukupuku te pukupuku, ka tūtohu pea tō tākuta i ngā maimoatanga pēnei i te chemotherapy . Ka taea e ēnei maimoatanga te āwhina i te whakaiti i ngā tohu me te whakaroa i te horapa o te pukupuku.

Ka taea e te rongoā te whakaora katoa?

Mena ka taea te tango katoa i te gastrinoma matepukupuku mā te pokanga, tera pea ka ora katoa te mate. Heoi, me tango katoa ngā pūtau matepukupuku i roto i te tinana. Ahakoa ka angitu te pokanga, me tango tonu e koe he rongoā hei whakahaere i te waikawa o te puku mō te toenga o tō oranga.

Mena kei a au tēnei āhuatanga, he aha taku e tumanako atu ai? (Te Matapae)

Ko te āhua o te mate mōu me tēnei mate ka whakawhirinaki ki te momo pukupuku. Kāore ngā gastrinomas kore-matepukupuku e mōrearea ki te ora. Heoi, me haere tonu te maimoatanga hei whakahaere i ngā taumata waikawa o te puku.

Heoi, ka rerekē te āhua mēnā he pukupuku matepukupuku tōu. Mēnā koinei te āhua, me mahi pea he pokanga me te maimoatanga whai muri i te matepukupuku.

He rerekē ngā reiti oranga mō te hunga e pāngia ana e te mate Zollinger-Ellison (ZES). E ai ki ngā raraunga, i muri i te tangohanga o ngā gastrinoma katoa mā te pokanga, neke atu i te 90% o te hunga e ora ana mō te 5 ki te 10 tau . Heoi, ki te kore e taea te tango i ngā pukupuku katoa, ka heke te reiti oranga mō te 5 tau ki te 43%. He mea nui kia mahara he tatauranga noa iho ēnei. Mena kei a koe tēnei mate, kōrero ki tō tākuta mō ngā mea ka taea e koe te tumanako.

Me pēhea taku tiaki i ahau anō? He aha taku e taea ai?

Kei tō āhua te tikanga. He maha ngā tāngata me tango rongoā hei whakaiti i te waikawa o te puku mō te toenga o ō rātou oranga. Ko te mate Zollinger-Ellison (ZES) ka puta mai i ngā gastrinomas. Ko te nuinga o ēnei pukupuku ka taea te mate pukupuku. Nō reira, ki te mea kua pāngia koe e ngā pukupuku pukupuku, me haere tonu koe ki te toro atu ki tō tākuta mō te tiaki whai muri kia kite ai mēnā kua hoki mai anō.

Āhea ahau me kite anō i te tākuta?

I muri i te maimoatanga, ki te kaha ake ngā tohu o te Zollinger-Ellison Syndrome (ZES), ki te puta mai rānei he tohu hou, me toro atu koe ki te tākuta tonu atu.

Ina kitea e koe he mate onge tōu, tera pea ka ohorere koe, ka mataku hoki. He uaua pea te rongo i tētahi mea pēnei i te wā ohorere, ahakoa kāore pea he tohu o tō mate. He maha pea āu pātai mō te pānga o te ZES ki a koe. Ka rerekē pea ngā whakautu ki aua pātai i runga i tō āhuatanga.

Ko te mea nui ko te kōrero i ō pātai me ō ruarua katoa ki te tākuta. Mā rātou e whakamārama ngā mea katoa ki a koe, ā, mā rātou anō hoki e tautoko i a koe.

Karere hei kawe ki te kāinga:

Āe, kia maumahara tātou ki ētahi o ngā kōrero nui kua kōrerotia nei:

• Ko te Zollinger-Ellison Syndrome (ZES) he mate i puta mai i te pukupuku e kiia nei ko te gastrinoma, e puta ai ngā mate puku me te korere nā te nui rawa o te waikawa o te puku.
• Tērā pea ka puta ngā tohu pēnei i te mamae o te puku, te ruaki toto, te mamae o te uma, me te hekenga taumaha.
• Ko te nuinga o ēnei pukupuku he matepukupuku.
• Ka tautuhia te mate mā roto i ngā whakamātautau pēnei i te whakamātautau toto, te matawai, me te endoscopy.
• Kei roto i te maimoatanga ngā rongoā (PPI), te pokanga, me te chemotherapy.
• Mā te kitenga me te maimoatanga wawe ka ārai i ngā raruraru me te whakatairanga i te whakaoranga.
• Mena kei a koe tēnei mate, me whai i ngā tohutohu a tō tākuta, me whakamātau i tō hauora i te wā tika, ā, me kōrero ki tō tākuta me te kore e huna i tetahi mea.

Ko tāku tumanako ka whai hua ēnei kōrero ki a koe. Kia ora tonu!

Te mate Zollinger-Ellison, te gastrinoma, te waikawa puku, ngā mate puku, te korere, ngā homoni, te mate pukupuku