Kodi chitetezo cha thupi lanu chikukuvutitsani? Tiyeni tiphunzire za Autoimmune Pancreatitis m'njira yosavuta!

Tili ndi chitetezo champhamvu m'thupi mwathu, sichoncho? Ndicho chimene timachitcha chitetezo chamthupi. Chimatiteteza polimbana ndi majeremusi, mabakiteriya, ndi mavairasi omwe amayambitsa matenda. Koma tangoganizirani, bwanji ngati nthawi zina chitetezo chathuchi chisokonezedwa ndi maselo abwino m'thupi mwathu ndikuyamba kuwaukira? Pamenepo, chimatchedwa ``Autoimmune Pancreatitis''. Mwachidule, chitetezo chamthupi chanu chimayamba kugwira ntchito motsutsana ndi kapamba wanu.

Kodi "Autoimmune Pancreatitis" ndi chiyani? Mwachidule...

Ganizirani za chitetezo cha mthupi la thupi lanu ngati gulu lankhondo lomwe limateteza dziko. Ntchito ya gulu lankhondo ili ndikuteteza dzikolo ku adani akunja (monga majeremusi ndi mavairasi). Koma mu `(Autoimmune Pancreatitis)`, gulu lankhondo ili limalakwitsa ndikuukira nzika zosalakwa za dziko lake (ndiko kuti, maselo athanzi mu kapamba) poganiza kuti ndi adani. Zotsatira zake, kapamba amatupa, amavulala, ndipo ntchito yake imasokonekera. Izi ndi zomwe timatcha kuti autoimmune pancreatitis .

Kodi matendawa ndi ofala bwanji?

Kwenikweni, `(Autoimmune Pancreatitis)` ndi matenda osowa kwambiri . Nthawi zambiri amapezeka mwa munthu m'modzi mwa anthu 100,000. Ngati titenga matenda otupa a kapamba kwa nthawi yayitali (`chronic pancreatitis`), pafupifupi 2% yokha mwa iwo amagwera m'gulu la `(Autoimmune Pancreatitis)`. Chifukwa chake, uwu si matenda omwe amakhudza aliyense.

Kodi pali mitundu ya `(Autoimmune Pancreatitis)`?

Inde, pali mitundu iwiri ya `(Autoimmune Pancreatitis)` makamaka. Tiyeni tiwone zomwe zili.

1. Mtundu 1 wa Pancreatitis Yodziyimira Payokha

Uwu ndi mtundu wofala kwambiri . Mu izi, tili ndi puloteni yambiri yotchedwa `(Immunoglobulin G4)` kapena `(IgG4)` m'thupi lathu. `(IgG4)` iyi ndi mtundu wa antibody. Pakakhala kutupa kapena kutupa kulikonse m'thupi, kuchuluka kwa `(IgG4)` kumeneku kumawonjezeka.

Koma mu mtundu woyamba uwu, vuto silili ndi kapamba kokha. Lingakhudzenso ziwalo zina m'thupi lathu. Mwachitsanzo:

• Ma duct a bile: Awa ndi machubu ofanana ndi machubu omwe amanyamula ndulu kuchokera ku chiwindi kupita kumatumbo ang'onoang'ono.
• Machubu a impso: Machubu omwe ali mu impso.
• Chiwindi
• Mapapu
• Chikhodzodzo cha ndulu
• Ma gland a malovu
• Chithokomiro cha chithokomiro

Kutupa ndi kuwonongeka kungachitikenso m'malo ngati awa.

2. Mtundu wachiwiri wa Pancreatitis Yodziyimira Payokha

Mtundu uwu umakhudza kapamba kokha . Chomwe chimachitika apa ndichakuti mtundu wa maselo oyera amagazi otchedwa ``neutrophils`` amawononga kapamba ndi ducts za kapamba. Vutoli nthawi zambiri limapezeka mwa achinyamata.Amakhalanso ndi mwayi waukulu wokhala ndi matenda otupa m'mimba (IBD).

Kodi zimayambitsa `(Autoimmune Pancreatitis)` ndi ziti? Kodi pali zinthu zina zoopsa?

Ofufuza akuyesetsabe kupeza chomwe chimayambitsa matendawa , koma nthawi zambiri amapezeka mwa anthu azaka zapakati pa 50 ndi 60. Komabe, amatha kuchitika msanga. Amuna ali ndi mwayi wowirikiza kawiri wodwala matendawa kuposa akazi.

Nthawi zina, amaganiza kuti ndi momwe chitetezo cha mthupi chimachitira ndi matenda a bakiteriya. Kuphatikiza apo, anthu omwe ali ndi matenda ena a autoimmune ali pachiwopsezo chachikulu chotenga matendawa. Mwachitsanzo:

• (Hashimoto's thyroiditis): Izi zimapangitsa kuti chithokomiro chisamagwire ntchito bwino (hypothyroidism).
• (Matenda otupa m'matumbo - IBD): Makamaka matenda monga `(ulcerative colitis)`.
• (Cholangitis yoyamba ya biliary)
• Retroperitoneal fibrosis: Kupangika kwa minofu yonga zipsera m'kati mwa mimba.
• Matenda a nyamakazi: Kutupa kwa mafupa.
• (Sarcoidosis)
• (Sjögren's syndrome)

Ngati muli ndi matenda ena a autoimmune ngati awa, ndi bwino kuda nkhawa pang'ono ndi Autoimmune Pancreatitis.

Kodi zizindikiro za `(Autoimmune Pancreatitis)` ndi ziti?

Poyamba matendawa , sipangakhale zizindikiro zilizonse . Komabe, pamene matendawa akupitirira, njira zotulutsira pancreatic zimayamba kuchepa, zomwe zimalepheretsa ma enzymes omwe amatulutsidwa ndi pancreatic kuti asadutse bwino.

Kutsekeka kwa duct ya pancreatic kungayambitse zizindikiro monga:

• Kupweteka kwa m'mimba pamwamba
• Kupweteka kwa msana wapakati
• Kutsegula m'mimba
• Kusanza/kutuluka nseru
• Kuchepetsa thupi

Chofunika: Zizindikiro zina izi zitha kuwonekanso mu khansa ya kapamba. Chifukwa chake, ngati muli ndi zizindikirozi, ndi bwino kuti musachite mantha ndikupita kwa dokotala nthawi yomweyo kuti mudziwe vuto lenileni . Kukhala ndi `(Autoimmune Pancreatitis)` sizitanthauza kuti muli ndi khansa.

Kuphatikiza apo, matenda a autoimmune pancreatitis angayambitse kutupa, kukula kosakhala khansa, ndi ma cysts odzaza madzi m'thupi la kapamba. Ngati kutupa kumeneku, ziphuphu, kapena ma cysts achitika m'mutu mwa kapamba wanu, amatha kutseka njira ya bile, zomwe zingalepheretse bile kulowa bwino m'matumbo ang'onoang'ono. Bile ili ndi utoto wotchedwa bilirubin. Bilirubin iyi ikasonkhana m'magazi, ingayambitse jaundice.Khungu ndi zoyera za maso zimakhala zachikasu (jaundice), ndipo mungamve kutopa. Pamene bilirubin ikuwonjezeka mu mkodzo , mkodzo umakhala wakuda . Pamene bilirubin ituluka m'matumbo , ndowe zimatha kukhala zotumbululuka .

Kodi ndi mavuto ati omwe angakhalepo chifukwa cha `(Autoimmune Pancreatitis)`?

Kutupa kosatha kwa kapamba kungayambitse nseru, kuchepa thupi, komanso kupweteka kosalekeza m'mimba ndi msana. Komanso, ngati maselo opanga insulin m' kapamba awonongeka , matenda a shuga amatha kuyamba.

Ma antibodies a IgG4 amatha kuukira osati kapamba kokha, komanso ziwalo zina, makamaka mu Mtundu 1. Ziwalo zimenezi zikuphatikizapo:

• Ma ducts a ndulu
• Ma gland a malovu
• Zilonda zam'mimba
• Chithokomiro cha chithokomiro (`Chithokomiro`)
• Impso
• Mtima
• Mapapo ndi pleura (mkati mwa mapapo)

Kodi matenda a autoimmune pancreatitis amachiritsidwa bwanji?

Kuti mudziwe matendawa molondola ndikutsimikiza kuti si khansa ya kapamba, pakufunika mayeso angapo. Muyenera kuchita mayeso ngati awa:

• Kuyezetsa magazi: Kuyezetsa magazi kumeneku kumayesa kuchuluka kwa IgG4 kodabwitsa, komanso kugwira ntchito kwa chiwindi ndi kuchuluka kwa mitundu ina ya maselo a magazi.
• Mayeso ojambulira: Izi zimayesa kukula kwa kapamba, ngati pali zipsera zilizonse, kapena ngati misempha ya m'mapapo yachepa. Zitsanzo za mayesowa ndi `(CT scan)` ndi `(MRI scan)`.
• Kufufuza za matenda a kapamba: Izi zimaphatikizapo kutenga minofu yaying'ono kuchokera ku kapamba wanu ndikuiyang'ana pansi pa maikulosikopu. Izi nthawi zambiri zimachitika kudzera mu njira yowunikira ya endoscopic yomwe imatchedwa Endoscopic Ultrasound (EUS). Mu njira iyi, dokotala wanu amaika chubu chachitali, chosinthasintha (chokhala ndi chipangizo chopepuka komanso cha ultrasound kumapeto kwake) m'mimba ndi m'matumbo mwanu kuti aone kapamba wanu. Kenako chitsanzo cha biopsy chimatengedwa kudzera m'mimba mwanu kapena m'matumbo. Nthawi zina, dokotala wa opaleshoni angafunike kudula khungu lanu pang'ono (laparoscopy) kuti atenge chitsanzo cha biopsy.
• Kuyesa kwa Corticosteroid: Izi zimathandizanso kutsimikizira matendawa. Mumapatsidwa ma steroids kwa kanthawi kochepa kuti muwone ngati milingo ya IgG4 yanu ikuchepa komanso ngati mayeso anu ojambulira zithunzi akukwera.

Kodi `(Autoimmune Pancreatitis)` imachiritsidwa bwanji?

Chodabwitsa n'chakuti, kwa anthu ochepa kwambiri, matendawa amatha okha popanda chithandizo chilichonse . Koma kwa ambiri, chithandizo chikufunika .

Pancreatitis ya Autoimmune imachiritsidwa makamaka ndi corticosteroids.Mtundu wa mankhwala otchedwa steroid. Mwachitsanzo, mankhwala monga `(prednisone)` kapena `(prednisolone)`. Mankhwalawa amagwira ntchito pochepetsa kutupa ndikuchepetsa chitetezo chamthupi chomwe chimagwira ntchito mopitirira muyeso. Chithandizo nthawi zambiri chimayamba ndi mlingo waukulu wa ma steroids. Kenako mlingo umachepetsedwa pang'onopang'ono (`wochepa`).

Ngati mulibe mavuto, nthawi zambiri simukusowa chithandizo china chilichonse. Chithandizo chomwe chikufunika chimadalira mtundu wa vuto. Ngati pali kuchepa kwa duct ya pancreatic (`duct inarrowing`), njira ingachitike kuti mutsegule duct ndikuyilimbitsa ndi chipangizo chopanda kanthu (`stent`).

Kodi ndingapewe kutenga `(Autoimmune Pancreatitis)`?

Ndipotu, palibe chomwe mungachite kuti mupewe matendawa chifukwa ndi vuto la chitetezo chamthupi chathu.

Kodi chiyembekezo cha anthu omwe ali ndi `(Autoimmune Pancreatitis)` ndi chotani?

Anthu ambiri amachira bwino atalandira chithandizo cha corticosteroid , ndipo palibe mavuto omwe amabwera chifukwa chokhala ndi matenda a autoimmune pancreatitis sikukhudza moyo wanu wonse .

Komabe, `(Autoimmune Pancreatitis)` ikhoza kubwereranso (kubwereranso) . Izi zimachitika makamaka kwa anthu omwe ali ndi mtundu woyamba (`Mtundu 1`). Matendawa amatha kubwereranso mkati mwa zaka zitatu zoyambirira atapezeka ndi matendawa. Munthu amene ali ndi matendawa amathanso kubwereranso amakhala ndi zovuta zambiri.

Kodi chimachitika n’chiyani ngati matendawa abwereranso?

Ngati atachiritsidwa bwino, ngakhale anthu omwe ali ndi matenda obwerezabwereza akhoza kukhala ndi moyo wathanzi komanso wokangalika .

Mungafunike kuyambanso kugwiritsa ntchito mankhwala a corticosteroid. Anthu ena amapitiriza kulandira mankhwala a steroid kwa zaka zingapo kuti zizindikiro zisabwererenso. Madokotala angayesenso mankhwala ena omwe amachiritsa chitetezo chamthupi chomwe chimagwira ntchito mopitirira muyeso (mankhwala oteteza chitetezo chamthupi komanso oletsa chitetezo chamthupi).

Kodi ndidzamva bwanji panthawi ya chithandizo?

Zotsatira zina zoyipa zingachitike mukamagwiritsa ntchito ma steroids. Mwachitsanzo, kuvutika m'mimba, njala yambiri, kusakhazikika, komanso kuvutika kugona. Zotsatirazi zitha kusokoneza pang'ono moyo watsiku ndi tsiku, koma ndi zakanthawi kochepa . Kuti mupindule kwambiri ndi chithandizo chanu cha Autoimmune Pancreatitis, ndikofunikira kupitiliza kumwa ma steroids monga momwe dokotala wanu wanenera .

Ngati zotsatirapo zake zikukuvutitsani kwambiri, onetsetsani kuti mwadziwitsa dokotala musanasiye kulandira chithandizo. Angakupatseni mankhwala ena kuti akuthandizeni kupeza mpumulo, kapena kusintha dongosolo lanu la chithandizo.

Kodi ndingabwerere liti kuntchito zanga zachizolowezi nditalandira chithandizo cha `(Autoimmune Pancreatitis)`?

Chithandizo cha steroid nthawi zambiri chimachepetsa zizindikiro za `(Autoimmune Pancreatitis)` mkati mwa milungu ingapo.Anthu ambiri amabwerera ku zochita zawo zachizolowezi zizindikiro zawo zikatha.

Matenda a Autoimmune Pancreatitis ndi matenda otupa omwe sapezeka kawirikawiri omwe angakhudze ntchito ya kapamba. Kuonana ndi dokotala wodziwa bwino matenda a kapamba kungakuthandizeni kupeza chithandizo chabwino chomwe mukufuna. Anthu ambiri amachira bwino atatha kumwa mankhwala a steroid . Anthu ena angafunike chithandizo china cha Autoimmune Pancreatitis kuti apeze mpumulo kwa nthawi yayitali.

Pomaliza, kumbukirani izi (Uthenga Wopita Nawo Kunyumba)

• Matenda a Autoimmune Pancreatitis ndi matenda osowa kwambiri omwe chitetezo chamthupi chanu chimaukira kapamba wanu.
• Ngati muli ndi zizindikiro monga kupweteka m'mimba, kuchepa thupi, kapena chikasu cha chikasu , onetsetsani kuti mwapeza upangiri wa dokotala .
• Iyi si khansa ya kapamba, koma chifukwa zizindikiro zake ndi zofanana, kuzindikira matenda molondola ndikofunikira .
• Chithandizo chachikulu ndi corticosteroids.
• Anthu ambiri amachira bwino akalandira chithandizo, koma matendawa amatha kubwereranso.
• Ndikofunikira kwambiri kutsatira malangizo a dokotala molondola kuti muchiritse msanga .

Kumbukirani, simuli nokha. Ndizachibadwa kukhala ndi maganizo ambiri mumtima mwanu mukakhala ndi vuto ngati ili. Choncho, khalani omasuka ndi dokotala wanu ndipo mufunseni mafunso anu. Alipo kuti akuthandizeni.

` Pancreatitis Yodziyimira payokha, Pancreatitis, Autoimmune, IgG4, Thanzi la Pancreas, Pancreatitis Sinhala, Thanzi la m'mimba