Kodi muli ndi mafunso okhudza cortisol? Tiyeni tidziwe bwino za 'hormone yovutitsa maganizo' iyi!

Mwina mwamvapo mawu akuti " cortisol , " makamaka ponena za " stress ." Koma cortisol si "stress hormone" yokha. Ndipotu, ndi hormone yofunika kwambiri yomwe imagwira ntchito yofunika kwambiri m'thupi lathu. Chifukwa chake, lero, tiyeni tikambirane za cortisol m'njira yosavuta yomwe mungamvetse.

Kodi cortisol ndi chiyani? Kodi ndi 'hormone yovutitsa maganizo' chabe?

Mwachidule, cortisol ndi mahomoni opangidwa ndi kutulutsa ndi kutulutsa ma adrenal glands athu - tinthu tating'onoting'ono tiwiri tomwe tili pamwamba pa impso. Ndi mtundu wa mahomoni otchedwa steroid otchedwa glucocorticoid .

Inde, monga momwe mungayembekezere, cortisol imagwirizana kwambiri ndi kupsinjika maganizo. Kaya timakumana ndi kupsinjika maganizo kwakukulu , kupsinjika maganizo kosatha , kapena kupsinjika maganizo koopsa, matupi athu amatulutsa cortisol. Ichi ndichifukwa chake imatchedwanso "hormone ya kupsinjika maganizo."

Kodi cortisol imakhudza bwanji thupi lathu?

Cortisol ndi mahomoni omwe amakhudza pafupifupi chiwalo chilichonse m'thupi lathu ndipo amalamulira ntchito zambiri zofunika. Tiyeni tiwone chomwe chili.

Kulamulira momwe mumayankhira mukapanikizika

Mukazindikira ngozi kapena mantha, thupi lanu nthawi yomweyo limalowa mu mkhalidwe wa "nkhondo kapena kuthawa," sichoncho? Panthawiyo, mahomoni monga adrenaline amatulutsidwa. Kenako, kuti mukhale maso, cortisol imayamba kutulutsidwa. Komanso, cortisol imathandiza kutulutsa shuga , kapena shuga, kuchokera ku chiwindi chathu kuti ipereke mphamvu zofunika panthawiyi.

Kagayidwe kachakudya ndi kuchuluka kwa shuga m'magazi

Kagayidwe kachakudya ndi njira yomwe matupi athu amagwiritsira ntchito mphamvu kuti akhale ndi moyo, kugwira ntchito, komanso kugwira ntchito. Cortisol imathandiza pa izi mwa kuwongolera momwe matupi athu amagwiritsira ntchito shuga kuti apange mphamvu.

Mwachitsanzo:

• Zimakhudza kapamba wathu, kuchepetsa kupanga insulin ndikuwonjezera kupanga glucagon. Ngakhale kuti insulin imachepetsa shuga m'magazi, glucagon imawonjezera kuchuluka kwa shuga.
• Zimakhudzanso minofu ya mafuta, chiwindi, ndi minofu m'thupi lathu, zomwe zimalamulira momwe timagwiritsira ntchito shuga.

Kuletsa kutupa

M'kanthawi kochepa, cortisol imatha kulimbitsa chitetezo chathu chamthupi pochepetsa kutupa , komwe ndi kutupa ndi kufiira m'thupi. Komabe, ngati kuchuluka kwa cortisol kuli kokwera nthawi zonse, thupi lathu limatha kuzolowera. Kenako zosiyana ndi izi zimachitika. Kutupa kumatha kuwonjezeka ndipo chitetezo chamthupi chimatha kufooka.

Kuwongolera kuthamanga kwa magazi

Sizikudziwika bwino momwe cortisol imalamulira kuthamanga kwa magazi. Komabe, zapezeka kuti kuchuluka kwa cortisol kungayambitse kuthamanga kwa magazi, ndipo kuchepa kwambiri kungayambitse kuthamanga kwa magazi.

Zimathandiza kuwongolera nthawi yogona ndi kudzuka

Kawirikawiri, kuchuluka kwa cortisol kumakhala kochepa tikagona usiku. Kumafika pachimake tisanadzuke m'mawa. Izi zikusonyeza kuti cortisol imakhudza kwambiri kayendedwe kathu ka circadian rhythm , kapena nthawi yogona ndi kudzuka.

Kodi thupi lathu limalamulira bwanji kuchuluka kwa cortisol?

Thupi lathu lili ndi njira yovuta kwambiri yowongolera kuchuluka kwa cortisol. Ntchito zazikulu mu izi zimaseweredwa ndi hypothalamus ndi pituitary gland muubongo wathu. Izi ziwiri zimalamulira kupanga cortisol ndi adrenal glands.

Umu ndi momwe zimachitikira:

1. Pamene kuchuluka kwa cortisol m'magazi mwanu kumatsika, hypothalamus imatulutsa hormone yotchedwa CRH (corticotropin-releasing hormone) .
2. Homoni iyi ya CRH imauza pituitary gland kuti ipange homoni yotchedwa ACTH (adrenocorticotropic hormone) .
3. Homoni iyi ya ACTH imalimbikitsa ma adrenal glands kuti apange cortisol ndikuyitulutsa m'magazi.

Choncho, kuti tisunge kuchuluka kwa cortisol m'thupi, ziwalo zonse zitatuzi—hypothalamus, pituitary gland, ndi adrenal glands—ziyenera kugwira ntchito bwino.

Kodi chimachitika ndi chiyani ngati kuchuluka kwa cortisol kumawonjezeka?

Ngati kuchuluka kwa cortisol kwakwera kwa nthawi yayitali, timatcha vuto la hypercortisolism . Izi nthawi zambiri zimachitika ndi vuto lotchedwa Cushing's syndrome .

Kodi ndi zifukwa ziti zomwe zimapangitsa kuti cortisol ichuluke?

• Kugwiritsa ntchito mankhwala a corticosteroid kwa nthawi yayitali (monga prednisone, prednisolone, dexamethasone) mu mlingo waukulu.
• Zotupa zomwe zimapanga ACTH - Izi nthawi zambiri zimayamba mu pituitary gland.
• Ma cysts omwe amapangika mu adrenal glands ndikupanga cortisol yochulukirapo.

Zizindikiro za cortisol yokwera

Ngati mulingo wa cortisol wakwera, kapena mukakhala ndi matenda a Cushing, mutha kuwona zizindikiro monga:

• Kulemera , makamaka pankhope ndi m'mimba.
• Mafuta amaikidwa kumbuyo pakati pa mapewa (chidutswa chofanana ndi chidutswa cha njati).
• Kuoneka kwa zizindikiro zazikulu, zofiirira pamimba.
• Kufooka kwa minofu m'manja ndi m'ntchafu zakumtunda.
• Kuchuluka kwa shuga m'magazi , zomwe nthawi zambiri zingayambitse matenda a shuga amtundu wa 2.
• Kuthamanga kwa magazi kwambiri .
• Kukula kwa tsitsi kosafunikira mwa akazi - vuto lotchedwa hirsutism .
• Kufooka kwa mafupa - Kufooka kwa mafupa ndi kusweka kwa mafupa kungachitike.

Kodi chimachitika ndi chiyani ngati kuchuluka kwa cortisol kumachepa?

Ngati kuchuluka kwa cortisol kuli kotsika kuposa kwachibadwa, madokotala amatcha hypocortisolism , kapena adrenal insufficiency . Pali mitundu iwiri ikuluikulu ya izi.

Kodi ndi zinthu ziti zomwe zimayambitsa kuchepa kwa cortisol m'thupi?

• Kulephera kwa adrenal cortex koyamba: Izi nthawi zambiri zimachitika chifukwa chitetezo cha mthupi chathu chimaukira ma adrenal glands. Izi zimatchedwanso matenda a Addison .
• Kulephera kwa adrenal kwachiwiri: Izi zimachitika ngati pituitary gland sikugwira ntchito mokwanira ( hypopituitarism ) kapena ngati pali chotupa cha pituitary.

Zizindikiro za cortisol yotsika

Ngati cortisol ili yochepa, mungakumane ndi zizindikiro monga:

• Kumva kutopa kwambiri (kutopa).
• Kuchepetsa thupi mosadziwa.
• Kusowa chilakolako cha chakudya .
• Kuthamanga kwa magazi kotsika .

Kodi ndingachite chiyani kuti ndichepetse kuchuluka kwa cortisol m'thupi?

Ngati muli ndi vuto ngati Cushing's syndrome, mungafunike chithandizo chamankhwala kuti muchepetse kuchuluka kwa cortisol m'magazi anu. Izi nthawi zambiri zimaphatikizapo mankhwala ndi/kapena opaleshoni. Komabe, pali zinthu zingapo zomwe tingachite kuti tithandize kuwongolera kuchuluka kwa cortisol m'magazi athu:

• Gonani bwino: Mavuto monga kusowa tulo komanso kugwira ntchito usiku angapangitse kuti cortisol ichuluke.
• Kuchita masewera olimbitsa thupi: Kuchita masewera olimbitsa thupi nthawi zonse kumathandiza kuti munthu azigona bwino komanso kuchepetsa nkhawa.
• Yesetsani kupuma mozama: Kupuma moyenerera kumalimbikitsa dongosolo lathu la mitsempha la parasympathetic - dongosolo lomwe limatonthoza thupi lathu ndikulamulira "kupuma ndi kugaya".
• Khalani okondwa ndipo mwetulire: Mukamwetulira, mahomoni otchedwa endorphins amatulutsidwa ndipo kuchuluka kwa cortisol kumachepa.
• Sungani ubale wabwino ndi anthu: Ubale wovuta komanso wovuta nthawi zonse ungayambitse kupsinjika maganizo nthawi zonse.