Kodi dokotala wanu wakuuzani kuti muli ndi matenda a shuga, kapena kuti mwatsala pang'ono kuyamba matenda a shuga (prediabetes)? Mukanena zimenezo, mwina mwamvapo mawu akuti "insulin resistance". Mwina mukudabwa kuti mawu atsopanowa ndi otani. Musachite mantha. Lero tikambirana za izi ndi mankhwala omwe amaperekedwa pa vutoli. Tiyeni timvetse bwino zinthu izi, monga kulankhula ndi mnzanu.
Kodi Kuzindikira kwa Insulin ndi Chiyani?
Mwachidule, insulin ndi mahomoni ofunikira kwambiri omwe amapangidwa ndi chiwalo m'thupi lathu chotchedwa kapamba. Shuga (shuga) yomwe ili mu chakudya chomwe timadya ikalowa m'magazi, ndiye chinsinsi chomwe chimathandiza shuga kulowa m'maselo a thupi ndikupanga mphamvu.
Tangoganizani kuti maselo m'thupi lanu ndi zitseko, ndipo insulin ndiyo kiyi yomwe imatsegula zitsekozo.
- Kukhala ndi mphamvu yabwino ya insulin kumatanthauza kuti: Mukayika kiyi iyi (insulin), chitseko (selo) chimatseguka mosavuta. Shuga m'magazi amalowa mosavuta m'maselo ndipo amasanduka mphamvu.
- Kukana kwa insulin kumatanthauza: Kiyi imeneyo imavutika kutsegula chitseko. Zili ngati chitseko chatsekedwa. Chifukwa chake chifukwa chitseko sichingatsegulidwe, shuga m'magazi amakwera. Kenako kapamba amayamba kupanga insulin yambiri, monga kubweretsa makiyi ambiri kuti atsegule chitseko chotsekedwa. Pakapita nthawi, izi ndi zomwe zimayambitsa matenda a shuga (mtundu wachiwiri wa shuga).
Choncho, zomwe mankhwala ochepetsa shuga m'magazi (insulin sensitivity) amachita ndi kupangitsa kuti zitseko zotsekeka zikhale zosavuta kutsegula. Izi zikutanthauza kuti zimathandiza kuti insulini izigwira ntchito bwino.
Kodi mankhwala akuluakulu a izi ndi ati?
Njira yabwino kwambiri yowonjezerera mphamvu ya insulin ndikusintha moyo wanu. Izi zikuphatikizapo kuchita masewera olimbitsa thupi nthawi zonse, kudya zakudya zopatsa thanzi, komanso kuwongolera kulemera kwanu. Komabe, dokotala wanu angakupatseninso mankhwala pamodzi ndi izi.
Pali mitundu iwiri ikuluikulu ya mankhwala.
1. Biguanides - Mankhwala okhawo omwe ali mgululi ndi Metformin yodziwika bwino.
2. Thiazolidinediones (TZDs) - Palinso mankhwala m'gululi.
Tiyeni tsopano tiwone mtundu uliwonse wa mitundu iyi padera.
Metformin, yomwe tonse timaidziwa
Metformin ndi mankhwala omwe amagwiritsidwa ntchito kwambiri pa matenda a shuga amtundu wachiwiri padziko lonse lapansi. Ngati muli ndi matenda a shuga, mwina mukumwa mankhwalawa.
Kodi metformin imagwira ntchito bwanji?
Metformin imathandiza kuwongolera shuga m'magazi m'njira ziwiri zazikulu:
- Amachepetsa kupanga shuga m'chiwindi: Chiwindi chathu chimapanganso shuga pamene thupi likufunikira. Popeza metformin imayang'anira njirayi, kuchuluka kwa shuga wosafunikira komwe kumasonkhana m'magazi kumachepa.
- Zimawonjezera mphamvu ya insulin m'minofu: Ichi ndiye chinthu chofunikira kwambiri. Maselo a minofu amayamba kuyankha bwino ku insulin. Kenako shuga m'magazi amalowa mosavuta m'minofu ndipo amasanduka mphamvu.
Kafukufuku wasonyeza kuti kumwa metformin kungathandize kuchepetsa kuyamba kwa matenda a shuga mwa anthu omwe ali pachiwopsezo komanso kuteteza matenda monga matenda a mtima.
| Mwachidule za Metformin | |
|---|---|
| Mlingo | Dokotala wanu ndiye adzakudziwitsani mlingo. Nthawi zambiri amayamba ndi mlingo wochepa kenako n’kuwonjezera pang’onopang’ono. Mungauzidwe kuti mumwe kamodzi kapena kawiri patsiku mukadya. |
| Zotsatira Zofala | Kusanza m'mimba, nseru, kusanza, makamaka kutsegula m'mimba kumatha kuchitika. Izi nthawi zambiri zimatha patatha masiku ochepa thupi likayamba kuzolowera mankhwala. Izi zitha kuchepetsedwa kwambiri mwa kumwa mankhwalawo limodzi ndi chakudya. |
| Zinthu zoti muzisamala nazo | Mankhwalawa si oyenera ngati muli ndi matenda aakulu a impso . Komanso, vuto losowa kwambiri koma loopsa lotchedwa "lactic acidosis" lingachitike. Ngati mukumva zizindikiro monga kupweteka kwa minofu, kutopa kwambiri, nseru, komanso kupuma mofulumira, pitani kuchipatala nthawi yomweyo. |
Metformin nthawi zambiri siimapangitsa kuti munthu awonjezere thupi monga mankhwala ena a shuga. Anthu ena amathanso kuchepetsa thupi.
Thiazolidinediones (TZDs)
Ili ndi gulu lina la mankhwala. Izi zimawonjezeranso mphamvu ya insulin. Pali mitundu iwiri ikuluikulu ya mankhwala m'gululi: Pioglitazone ndi Rosiglitazone .
Madokotala nthawi zambiri amalangiza metformin kaye. Ngati n'kovuta kuilamulira kapena pazifukwa zina, mungaganizire za mtundu uwu wa mankhwala a TZD.
Chofunika kwambiri: Ngati muli ndi vuto la mtima kapena munali ndi vuto la kutsekeka kwa mtima, mankhwala a TZD awa sali oyenera konse , chifukwa angapangitse vutoli kukhala loipa kwambiri.
| Mtundu wa mankhwala | Zinthu zoti mudziwe |
|---|---|
| Pioglitazone | Izi zimawonjezeranso mphamvu ya insulin. Kafukufuku wina wasonyeza kuti zitha kukhudza chiwindi, kuonjezera chiopsezo cha khansa ya chikhodzodzo, komanso kuonjezera chiopsezo cha kusweka kwa mafupa. |
| Rosiglitazone | Izi zimagwiranso ntchito mofanana ndi mankhwala omwe ali pamwambapa. Ngakhale kuti kale panali nkhawa zokhudza chiopsezo cha matenda a mtima, maphunziro ena sanatsimikizire izi. Komabe, ndikofunikira kudziwa za matenda a mtima mukamagwiritsa ntchito mankhwala onsewa. |
| Zotsatira zoyipa za TZD | Zizindikiro zake zingakhale monga kunenepa kwambiri, kutupa chifukwa cha kusunga madzi m'thupi, kupweteka pachifuwa, komanso kupuma movutikira. Ngati mukukumana ndi zizindikiro izi, funsani dokotala nthawi yomweyo. |
Kodi mumasankha bwanji mankhwala oyenera kwa inu?
Funso ili ndi lofunika kwambiri. Koma si lanu loti liyankhe, ndi la dokotala wanu . Chifukwa amaganizira zinthu zambiri akamasankha mankhwala oyenera kwa inu.
- Kodi matenda anu a shuga ali bwanji?
- Kodi muli ndi matenda ena aliwonse (matenda a mtima, matenda a impso, matenda a chiwindi)?
- Kodi zaka zanu ndi moyo wanu ndi ziti?
- Kodi zotsatirapo zake ndi ubwino ndi kuipa kwa mankhwalawa ndi ziti?
Pambuyo poganizira zonsezi, ndiye amasankha mankhwala oyenera komanso otetezeka komanso mlingo wake kwa inu.Musagwiritse ntchito mankhwala omwe mnzanu akumwa, kapena mankhwala omwe wina akulangiza, pobwezera.
Uthenga Wopita Nawo Kunyumba
- Kukana kwa insulin kumachitika pamene maselo a thupi lanu sayankha bwino ku insulin. Ichi ndiye chifukwa chachikulu cha matenda a shuga a mtundu wachiwiri.
- Mankhwala a Metformin ndi TZD ndi omwe amathandiza kuwonjezera mphamvu ya insulin.
- Chofunika kwambiri monga mankhwala, ndipo mwinanso chofunika kwambiri, kudya zakudya zoyenera komanso kuchita masewera olimbitsa thupi nthawi zonse n'kofunika kwambiri kuti munthu azitha kumva bwino insulin.
- Dokotala wanu yekha ndi amene angakulembereni mankhwala. Imwani mlingo womwe wakupatsani, monga momwe mwalangizidwira, komanso panthawi yoyenera.
- Musanayambe mankhwala atsopano, kambiranani momasuka ndi dokotala wanu za ubwino wake, zoopsa zake, ndi zotsatira zake zomwe zingachitike. Musachite mantha kapena kuchita manyazi. Ndi ufulu wanu.
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