Kodi mukudziwa za 'hormone yachimwemwe' iyi, dopamine? Tiyeni tikambirane mwatsatanetsatane!

Kodi munamvapo za chinthu chotchedwa 'hormone yachimwemwe'? Nthawi zina mumangomva chisangalalo ndi chisangalalo, sichoncho? Chomwe chimagwirizana kwambiri ndi malingaliro amenewo chimatchedwa Dopamine. Chimathandizira ntchito zambiri zofunika m'thupi lathu. Chifukwa chake, lero, tiyeni tiphunzire zambiri za Dopamine.

Kodi dopamine kwenikweni ndi chiyani?

Mwachidule, dopamine ndi mankhwala achilengedwe omwe amapangidwa muubongo wathu. Ndi a gulu la ma neurotransmitters otchedwa ``Monoamine neurotransmitters.'' Ndi ``Neurotransmitter'', kutanthauza neurotransmitter . Tangoganizirani, maselo amitsempha muubongo wathu amatumizirana mauthenga. Dopamine ndi 'mthenga wa mankhwala' yemwe amathandiza kusinthana mauthenga amenewo. Zimathandiza kunyamula mauthenga awa kuchokera muubongo kupita ku thupi lathu lonse.

Komanso, dopamine ndi hormone . Dopamine, epinephrine, ndi norepinephrine ndi ma catecholamines akuluakulu. Ma hormone amenewa amapangidwa ndi ma adrenal glands, omwe ali pamwamba pa impso zathu. Kuphatikiza apo, hypothalamus muubongo wathu imatulutsanso dopamine, neurohormone.

Kodi dopamine imachita chiyani m'thupi lathu?

Dopamine ndi mankhwala omwe amagwira ntchito m'njira zambiri zofunika m'thupi lathu. Tiyeni tiwone chomwe chili.

Dopamine monga neurotransmitter

Monga neurotransmitter, dopamine imathandizira izi:

• Kuyenda: Kumathandiza kulamulira kuyenda kwa thupi lathu.
• Kukumbukira: Izi ndizofunikira kwambiri pokumbukira zinthu.
• Mphoto yosangalatsa ndi chilimbikitso: Tikasangalala ndi chinthu china, timamva ngati tichitanso, ndipo izi zimachitika chifukwa cha dopamine.
• Khalidwe ndi kuzindikira: Zimakhudzanso machitidwe athu ndi luso lathu lomvetsa china chake.
• Chenjezo: Zimakuthandizani kuti musamaganizire kwambiri pa chinthu china.
• Kugona ndi kudzuka: Zimathandizanso kuwongolera momwe timagona ndi kudzuka.
• Maganizo: Izi zimakhudzanso momwe maganizo athu alili, kaya tili okondwa kapena achisoni.
• Kuphunzira: Dopamine ndi yofunika kwambiri pophunzira zinthu zatsopano.
• Kuyamwitsa: Kumakhudzananso ndi njira yopangira mkaka kwa amayi oyamwitsa.

Dopamine monga Hormone

Dopamine ndi mahomoni omwe amatulutsidwa m'magazi mwathu. Amathandizanso pang'ono pa momwe thupi limayankhira "nkhondo kapena kuthawa" tikakumana ndi chiwopsezo, monga ngozi. Izi zikutanthauza kuti, ngati mwadzidzidzi muwona chinthu choopsa, chimakhudza momwe thupi lanu limachichitira.

Kuphatikiza apo, dopamine, monga hormone, imachitanso izi:

• Zimathandiza kukulitsa (mu milingo yotsika - `(Vasodilator)`) kapena kufinya (mu milingo yokwera - `(Vasoconstrictor)`) mitsempha yamagazi.
• Zimawonjezera kutuluka kwa sodium (mchere) ndi mkodzo m'thupi.
• Zimachepetsa kuchuluka kwa insulin komwe kumapangidwa ndi kapamba wathu.
• Zimachedwetsa kuyenda kwa chakudya kudzera m'thupi la m'mimba (GI) ndipo zimateteza mkati mwa thupilo.
• Amachepetsa ntchito ya ma lymphocyte, maselo m'thupi.

Kodi dopamine imatipangitsa bwanji kukhala osangalala?

Dopamine imatchedwanso "hormone yosangalatsa" chifukwa imatipangitsa kukhala osangalala komanso okhutira. Komanso, tikasangalala ndi chinthu china, ndi dopamine iyi yomwe imatilimbikitsa kuchitanso.

Taganizirani izi motere: Dopamine ndi gawo la "dongosolo lathu la mphotho." Dongosololi lapangidwa kuti litipatse mphotho, kumva chisangalalo, tikamachita zinthu zomwe timafunikira kuti tipulumuke (monga kudya, kumwa, kupikisana, ndi kubereka). Chifukwa chake, monga anthu, ubongo wathu umakhala wolumikizidwa kuti upeze machitidwe omwe amatulutsa dopamine kuchokera ku dongosololi la mphotho. Mukachita chinthu chosangalatsa, ubongo wanu umatulutsa dopamine yambiri. Kenako mumamva bwino, ndipo mumapitiliza kufunafuna kumverera kumeneko.

Ichi ndichifukwa chake timakonda kwambiri zakudya zina, makamaka zakudya zopanda thanzi komanso shuga. Tikadya, ubongo wathu umatulutsa dopamine yambiri. Kenako timasangalala, ngati kuti tili pamwamba pa dziko lapansi, ndipo timafunanso kuti tipezenso zomwezo.

Kodi mumamva bwanji kukhala ndi dopamine yokwanira?

Ngati mulingo wanu wa dopamine uli bwino, mudzamva izi:

• Zikuoneka kuti muli okondwa.
• Zikuoneka kuti muli ndi chidwi komanso muli ndi chidwi.
• Zili ngati kukhala maso, muli ndi maganizo abwino.
• Zikuoneka kuti mungathe kugwira ntchito ndi chidwi chabwino.

Kodi chimachitika ndi chiyani ngati kuchuluka kwa dopamine kumachepa?

Ngati kuchuluka kwa dopamine kumachepa, mungakumane ndi zinthu monga:

• Mukuwoneka otopa kwambiri.
• Zikuoneka kuti palibe chidwi ndi chilichonse.
• Zikuoneka ngati palibe chimwemwe.

Kuphatikiza apo, zizindikiro zotsatirazi zitha kuchitika:

• Kutaya kukumbukira.
• Kusintha kwadzidzidzi kwa malingaliro (kusintha kwa malingaliro).
• Mavuto a tulo.
• Kuvuta kuyika maganizo pa chinthu.
• Kuchepa kwa chilakolako chogonana.

Nanga bwanji ngati kuchuluka kwa dopamine kumawonjezeka?

Ngati milingo ya dopamine yakwera kwambiri, mungamve ngati:

• Chimwemwe chachikulu, chisangalalo (Euphoric).
• Kumva mphamvu zazikulu.
• Chilakolako chogonana mopitirira muyeso.

Komabe, palinso zovuta zina zomwe zingachitike chifukwa cha kukwera kwa dopamine. Izi ndi izi:

• Kuvuta kugona.
• Kupanga zisankho mopupuluma, mopupuluma (Kusalamulira bwino maganizo).
• Kukhala wankhanza kwambiri.

Ndi matenda ati omwe amagwirizanitsidwa ndi kuchuluka kwa dopamine kotsika/kokwera?

Pali matenda ambiri omwe amagwirizanitsidwa ndi kuchuluka kwa dopamine kotsika kapena kokwera. Koma pali zambiri zomwe zikupezekabe pankhaniyi. Mwachitsanzo, kodi matenda amayamba chifukwa cha kuchuluka kwa dopamine kotsika/kokwera, kapena kodi matenda amasintha kuchuluka kwa dopamine? Mwina zonsezi ndi zonse ziwiri. Chinanso n'chakuti ntchito ya neurotransmitter imodzi monga dopamine siingaoneke yokha. Chifukwa, ma neurotransmitter ena ambiri, mahomoni, ndi mankhwala muubongo ndi thupi lathu amagwira ntchito limodzi. Chifukwa chake izi ndi zovuta pang'ono.

Komabe, pali matenda angapo okhudzana ndi kusintha kwa kuchuluka kwa dopamine.

Matenda okhudzana ndi kusowa kwa dopamine:

• Matenda a Attention Deficit Hyperactivity Disorder (ADHD): Anthu omwe ali ndi vutoli apezeka kuti ali ndi dopamine yochepa.
• Matenda a Parkinson: Izi zimachitika chifukwa cha kuwonongeka kwa maselo a muubongo omwe amapanga dopamine.
• Matenda a miyendo yosakhazikika: Matenda omwe amadziwika ndi kusasangalala m'miyendo komanso chilakolako chofuna kusuntha miyendo.

Matenda okhudzana ndi kuchuluka kwa dopamine:

• Kukonda zinthu mopitirira muyeso: Kusangalala kwambiri ndi zochita zambiri m'maganizo.
• Kunenepa Kwambiri: Kafukufuku wina wasonyeza kuti pali kugwirizana pakati pa dopamine ndi kunenepa kwambiri.
• Chizolowezi: Dopamine imagwira ntchito yaikulu pa chizolowezi cha zinthu monga mankhwala osokoneza bongo ndi kutchova juga.

Matenda okhudzana ndi kuchepa ndi kuchuluka kwa dopamine:

Schizophrenia : Iyi ndi matenda ovuta amisala. Zizindikiro zina (monga kuganiza molakwika, kuganiza molakwika) zingayambitsidwe ndi kuchuluka kwa dopamine m'mbali zina za ubongo. Zizindikiro zina (monga kusamvera) zingayambitsidwe ndi kuchepa kwa dopamine m'mbali zina za ubongo.

Kodi mankhwala otani okhudzana ndi dopamine ndi otani?

Pali mankhwala osiyanasiyana omwe amatha kuchepetsa kuchuluka kwa dopamine kapena kuchita ngati dopamine. Tiyeni tiwone.

Kodi Dopamine Agonists ndi chiyani?

Mankhwala otchedwa dopamine agonists ndi mtundu wa mankhwala omwe amagwira ntchito mofanana ndi dopamine yachilengedwe. Amamangirira ku ma dopamine receptors muubongo ndikuwalimbikitsa. Monga momwe maselo amitsempha amayankhira ku dopamine yachilengedwe.

Mankhwalawa amagwiritsidwa ntchito pochiza matenda a Parkinson, kuvutika maganizo, matenda opumira miyendo, ADHD, chilakolako chochepa chogonana, komanso hyperprolactinemia (kuwonjezeka kwa mahomoni omwe amapanga mkaka).

Zitsanzo zina:

• Pa matenda a Parkinson: `(Pramipexole (Mirapex®))`, `(Ropinirole (Requip®))`, `(Rotigotine (Neupro®))`, `(Apomorphine HCl (KYNMOBI®))`.
• Kwa kuvutika maganizo: `(Pramipexole (Mirapex®))`.
• Kwa iwo omwe ali ndi chilakolako chochepa chogonana: `(Pramipexole (Mirapex®))`.
• Kwa hyperprolactinemia: `(Bromocriptine (Parlodel®))`, `(Cabergoline (Dostinex®))`.

Kodi Otsutsa Dopamine Ndi Chiyani?

Mankhwala oletsa dopamine ndi mtundu wa mankhwala omwe amamangirira ku ma dopamine receptors muubongo ndikuwaletsa. Izi zikutanthauza kuti, amaletsa dopamine kufika mu selo lotsatira la mitsempha. Mankhwala ambiri oletsa matenda amisala omwe amagwiritsidwa ntchito pochiza matenda amisala ali m'gulu ili.

Izi zimagwiritsidwa ntchito pochiza matenda a schizophrenia , matenda a bipolar, komanso nseru ndi kusanza.

Zitsanzo:

Kwa matenda a schizoaffective : `(Aripiprazole (Abilify®))`, `(Risperidone (Risperdal®))`, `(Ziprasidone (Geodon®))`.
• Kwa matenda a bipolar: `(Risperidone)`, `(Olanzapine (Zyprexa®))`, `(Ziprasidone)`.
• Pa nseru ndi kusanza: `(Metoclopramide (Reglan®))`, `(Droperidol (Inapsine®))`.

Kodi Dopamine Reuptake Inhibitors ndi chiyani?

Mankhwala oletsa kubwerezabwereza kwa dopamine ndi mtundu wa mankhwala omwe amaletsa maselo amitsempha omwe adatulutsa dopamine kuti asayamwitsenso. Izi zimasiya dopamine yambiri muubongo, yomwe ingagwiritsidwe ntchito ndi maselo ambiri amitsempha.

Mankhwalawa amathandiza ndi kuvutika maganizo, kugona tulo topitirira muyeso, komanso zizolowezi monga kusuta fodya ndi kudya mopitirira muyeso.

Zitsanzo:

• Kwa kuvutika maganizo: `(Bupropion (Wellbutrin®))`.
• Kwa matenda a narcolepsy: `(Modafinil (Provigil))`.
• Kwa chizolowezi cha cocaine: `(Bupropion)`, `(Nomifensine)`, `(Benztropine (Cogentin))`, `(Mazindol)`.
• Kusiya kusuta: `(Bupropion)`.

Kodi Levodopa ndi chiyani?

Levodopa ndiye mankhwala akuluakulu omwe amagwiritsidwa ntchito pochiza matenda a Parkinson. Matenda oyendayenda mwa odwala a Parkinson amayamba chifukwa cha kusowa kwa dopamine. Kuti Levodopa iperekedwe mwachindunji ku ubongo (m'malo mwa ziwalo zina za thupi), imaperekedwa pamodzi ndi mankhwala otchedwa Carbidopa. Ikafika mu ubongo, Levodopa imasandulika dopamine.

Kodi ntchito ya dopamine ndi yotani pa chizolowezi cha mankhwala osokoneza bongo?

Tikamagwiritsa ntchito mankhwala osokoneza bongo, amasokoneza momwe maselo amitsempha muubongo wathu amatumizira ndikulandira mauthenga. Mankhwala osokoneza bongo monga chamba ndi heroin amagwira ntchito ngati ma neurotransmitters achilengedwe. Mankhwala osokoneza bongo monga amphetamines ndi cocaine amachititsa kuti ma neurotransmitters ambiri achilengedwe (monga dopamine) atulutsidwe nthawi yomweyo, kapena amasiya kuyamwanso.

Mankhwalawa amalimbitsa kwambiri "malo opatsa mphotho" muubongo wathu. Tikapitiriza kugwiritsa ntchito mankhwala osokoneza bongo kwa nthawi yayitali, gawo lina la ubongo limakhala lopanda mphamvu, ndipo sitimva bwino monga momwe tingachitire ndi china chilichonse kupatula mankhwala osokoneza bongo. Komanso, kuti tipeze chisangalalo chomwecho, tiyenera kumwa mankhwala ambiri. Nthawi yomweyo, gawo lina la ubongo limakhala losavuta kumva kusasangalala (monga nkhawa ndi kusakhazikika) komwe kumachitika pamene zotsatira za mankhwala osokoneza bongo zatha. Kenako timayesedwa kuti tigwiritsenso ntchito mankhwalawa kuti tichotse kusasangalalako. Chifukwa chake, chizolowezi ndi vuto lalikulu lomwe limayamba kudzera m'njira zosiyanasiyana.

Asayansi tsopano akuganiza kuti ntchito ya dopamine sikuti imangobweretsa chisangalalo mwachindunji, koma kukumbukira zochitika zosangalatsa ndikuzilimbitsa kuti zigwiritsidwe ntchito mobwerezabwereza. Chifukwa chake, dopamine ikakula mwadzidzidzi chifukwa cha mankhwala osokoneza bongo, imaphunzitsa ubongo kukumbukira zomwe zidakuchitikirani. Ubongo wanu umagwirizanitsa kugwiritsa ntchito mankhwala osokoneza bongo ndi zizolowezi zanu zonse ndi zizindikiro zina zonse zomwe zimagwirizana nawo. Ichi ndichifukwa chake mutha kubwerera kumalo komwe mudagwiritsa ntchito mankhwala osokoneza bongo, ngakhale mutasiya kuwagwiritsa ntchito nthawi yayitali, ndikumvabe ngati mukufunikiranso mankhwalawa.

Kodi mungawonjezere bwanji kuchuluka kwa dopamine mwachilengedwe?

Mungayesere zinthu zomwe zingathandize kukweza kuchuluka kwa dopamine mwachibadwa. Komabe, kafukufuku wowonjezereka akufunika pa zotsatira za chakudya ndi zakumwa pa ma neurotransmitters monga dopamine.

• Idyani zakudya zokhala ndi magnesium ndi tyrosine. Izi ndi zinthu zomwe zimapangitsa kuti dopamine ipangidwe. Tyrosine ndi amino acid. Imayamwa ndi thupi ndipo imapita ku ubongo, komwe imasanduka dopamine. Zakudya zomwe zimanenedwa kuti zimawonjezera dopamine ndi monga: nkhuku, amondi, maapulo, ma avocado, nthochi, beets, chokoleti (makamaka chokoleti chakuda), ndiwo zamasamba zobiriwira, tiyi wobiriwira, nyemba za lima, oatmeal, malalanje, mtedza wa macadamia, mbewu za sesame ndi dzungu, tomato, turmeric, vwende, ndi tirigu.
• Chitani zinthu zomwe zimakupangitsani kukhala osangalala komanso omasuka. Izi zikuganiziridwanso kuti zimawonjezera kuchuluka kwa dopamine. Zitsanzo ndi izi: kuchita masewera olimbitsa thupi, kusinkhasinkha, kuchita yoga, kupatsidwa masaji, kusewera ndi chiweto, kuyenda m'chilengedwe, kapena kuwerenga buku.

Pomaliza, chinthu chofunikira kwambiri (Uthenga Wopita Nawo Kunyumba)

Dopamine ndi neurotransmitter ndi mahomoni. Imagwira ntchito yofunika kwambiri m'thupi lathu, makamaka kuyenda, kukumbukira, chisangalalo, ndi chilimbikitso. Kuchepa kapena kukwera kwa dopamine kwagwirizanitsidwa ndi mavuto angapo azaumoyo wamaganizo ndi matenda amitsempha.

Dopamine ndi chinthu chovuta kwambiri. Pali kafukufuku wambiri womwe ukuchitidwa pa momwe imagwirizanirana ndi matenda komanso momwe imagwirira ntchito ndi ma neurotransmitters ena, mahomoni, ndi mankhwala.

Ngati mukuganiza kuti muli ndi zizindikiro za kuchepa kapena kuchuluka kwa dopamine m'magazi, onetsetsani kuti mwaonana ndi dokotala wanu. Iye akhoza kuwunika zizindikiro zanu, kuchita mayeso ofunikira, ndikukuthandizani kupanga dongosolo loyenera la chithandizo ngati muli ndi vuto linalake. Kumbukirani, musamadzipatse mankhwala, makamaka ndi chinthu chovuta ngati ichi.

Dopamine , neurotransmitter, mahomoni, ubongo, thanzi la maganizo, matenda a Parkinson, chizolowezi