Kodi mukudziwa za Dopamine ya 'hormone yachimwemwe'? Tiyeni tikambirane mwatsatanetsatane - Nirogi Lanka

Kodi mudamvapo za "hormone yosangalatsa"? Kodi mukudziwa momwe zimakhalira mukangomva kusangalala, kulimbikira, kapena kusangalala mwadzidzidzi? Zimenezi zimagwirizana kwambiri ndi chinthu chotchedwa dopamine. Chimagwira ntchito yofunika kwambiri m'thupi lanu. Chifukwa chake, tiyeni tiphunzire bwino lomwe za dopamine ndi Nirogi Lanka.

Kodi kwenikweni Dopamine ndi chiyani?

Mwachidule, dopamine ndi mankhwala achilengedwe omwe amapangidwa muubongo wanu. Ndi m'gulu la mankhwala omwe amadziwika kuti monoamine neurotransmitters.Ganizirani maselo amitsempha muubongo wanu ngati kuti amalankhulana nthawi zonse; dopamine imagwira ntchito ngati "chotumizira mankhwala" chomwe chimathandiza kutumiza mauthengawa m'malo osiyanasiyana pakati pa maselo. Imagwira ntchito yofunika kwambiri potumiza mauthengawa kuchokera muubongo wanu kupita ku thupi lanu lonse.

Dopamine imagwiranso ntchito ngati mahomoni . Pamodzi ndi epinephrine ndi norepinephrine, imagawidwa ngati catecholamine . Mahomoni amenewa amapangidwa makamaka ndi ma adrenal glands anu, omwe amakhala ngati zipewa zazing'ono pamwamba pa impso zanu. Kuphatikiza apo, hypothalamus ya ubongo wanu imatulutsa dopamine ngati neurohormone .

Kodi dopamine imagwira ntchito bwanji m'thupi lanu? Ku Nirogi Lanka, tikukuthandizani kumvetsetsa ntchito zake zofunika kwambiri.

Dopamine imagwira ntchito zambiri zofunika m'thupi. Tiyeni tiwone bwino zomwe imachita.

Dopamine monga Wotumiza Maubongo

Monga neurotransmitter, dopamine imathandizira izi:

• Kuyenda: Kumathandiza kulinganiza ndi kulamulira kuyenda kwa thupi lanu.
• Kukumbukira: Ndikofunikira kwambiri pophunzira ndi kusunga chidziwitso.
• Mphoto Yosangalatsa ndi Chilimbikitso: Mukasangalala ndi ntchito inayake, dopamine imalimbitsa khalidwe limenelo, zomwe zimakupangitsani kufuna kubwerezanso.
• Khalidwe ndi Kuzindikira: Zimakhudza momwe mumagwiritsira ntchito chidziwitso ndikusintha machitidwe anu.
• Chenjezo: Zimakuthandizani kuyang'ana kwambiri ndikukhalabe ndi chidwi.
• Kugona ndi Kudzuka: Kumachita gawo lofunika kwambiri pakulamulira nthawi yanu yogona ndi kudzuka.
• Maganizo: Zimakhudza kwambiri momwe mukumvera, zomwe zimakhudza momwe mumamvera mumtima mwanu kapena mukumva chisoni.
• Kuphunzira: Ndikofunikira kwambiri pakupeza luso ndi chidziwitso chatsopano.
• Kuyamwitsa: Kumathandiza kuwongolera mahomoni omwe amakhudza kuyamwitsa.

Dopamine monga Hormone

Dopamine ikamagwira ntchito ngati mahomoni, imalowa m'magazi mwanu. Imathandizira kuti thupi lanu liziyankha "nkhondo kapena kuthawa" panthawi yovuta. Kwenikweni, ngati mukukumana ndi chiopsezo chadzidzidzi, dopamine imathandiza kulamulira momwe thupi lanu limachitira ndi nkhawa imeneyo.

Kuphatikiza apo, monga hormone, dopamine imagwira ntchito zina zofunika kwambiri:

• Zimathandiza kukulitsa mitsempha yamagazi (mu mlingo wochepa) kapena kuichepetsa (mu mlingo wokwera).
• Zimalimbikitsa impso zanu kutulutsa sodium (mchere) ndi mkodzo wambiri.
• Zimachepetsa kupanga insulin mu kapamba wanu.
• Zimachedwetsa liwiro limene chakudya chimadutsa m'mimba (GI) , zomwe zimathandiza kuteteza mkati mwake.
• Zimachepetsa ntchito ya ma lymphocyte m'thupi lanu.

Kodi dopamine imakupangitsani bwanji kumva bwino?

Dopamine nthawi zambiri imatchedwa "hormone yosangalatsa" chifukwa imayambitsa kumverera kosangalatsa komanso kukhutira. Imakulimbikitsaninso kuti muzichita zinthu zomwe zakupatsani mphotho yabwino.

Ganizirani za dopamine ngati gawo lofunika kwambiri la "dongosolo la mphotho" muubongo wanu. Dongosololi linapangidwa kuti lipereke chikhutiro chachikulu mukamachita zinthu zofunika kuti mupulumuke—monga kudya, kukhalabe ndi madzi okwanira, kapena kukwaniritsa zolinga. Ubongo wanu umakhala wolumikizidwa kuti upeze zinthu zomwe zimayambitsa kutulutsa dopamine. Mukachita chinthu chosangalatsa, ubongo wanu umatulutsa dopamine yambiri, yomwe imakupangitsani kumva bwino ndikukulimbikitsani kuti mufufuzenso zomwezo.

Ichi ndichifukwa chake zakudya zina, makamaka "zakudya zopanda pake" zomwe zakonzedwa kwambiri komanso zotsekemera, zimatha kukhala zosokoneza kwambiri. Kudya zakudyazi kumayambitsa kutulutsidwa kwakukulu kwa dopamine muubongo wanu, zomwe zimapangitsa kuti mukhale ndi "kutopa" kwakanthawi komwe mumamva kuti mukukakamizidwa kubwereza.

Kodi mlingo woyenera wa dopamine umamveka bwanji?

Ngati milingo yanu ya dopamine ili bwino komanso yabwino, mutha kumva izi:

• Kawirikawiri amakhala wokondwa komanso wokhutira.
• Wolimbikitsidwa komanso wolimbikitsidwa.
• Chenjezo ndi kudzipereka.
• Wokhazikika komanso wokhoza kuyang'ana bwino.

Kodi chimachitika ndi chiyani ngati milingo ya dopamine ili yotsika?

Kuchepa kwa dopamine kungakupangitseni kukhala ndi zotsatirazi:

• Kutopa nthawi zonse kapena mphamvu zochepa.
• Kusowa chilimbikitso kapena changu.
• Kusasangalala kapena kusasamala nthawi zonse.

Kuphatikiza apo, mungazindikire:

• Kuvuta kukumbukira.
• Kusintha kwa maganizo.
• Kusokonezeka kwa tulo.
• Kulephera kuyang'ana kwambiri.
• Kuchepetsa chilakolako chogonana.

Kodi chimachitika ndi chiyani ngati milingo ya dopamine ili yokwera kwambiri?

Kuchuluka kwa dopamine m'magazi kungayambitse zinthu monga:

• Chisangalalo chachikulu kapena kusangalala kwambiri.
• Kuchita zinthu mopitirira muyeso kapena mphamvu zambiri.
• Kuwonjezeka kwa chilakolako cha kugonana.

Komabe, kuchuluka kwa dopamine nthawi zonse kumatha kukhala ndi mavuto akulu. Ngati mukumva zizindikiro, chonde funsani chithandizo chamankhwala kuchipatala chapafupi kapena imbani 911 ngati ndi vuto ladzidzidzi.

• Kuvuta kugona kapena kugona mokwanira.
• Kulephera kulamulira maganizo, zomwe zimapangitsa kuti munthu asankhe zinthu mopupuluma kapena mwadzidzidzi.
• Kuwonjezeka kwa nkhanza.

Ndi matenda ati omwe amagwirizanitsidwa ndi kuchuluka kwa dopamine kosakhazikika?

Matenda ambiri amagwirizanitsidwa ndi kuchuluka kwa dopamine komwe kumakhala kokwera kwambiri kapena kotsika kwambiri. Komabe, sayansi ikusinthabe m'derali. Nthawi zambiri sizikudziwika ngati kusalingana kwa dopamine kumayambitsa vuto, kapena ngati vuto linalake limayambitsa kusalingana—ndipo nthawi zambiri, ndi kuphatikiza zonse ziwiri. Kuphatikiza apo, ubongo wanu ndi dongosolo lovuta; dopamine sigwira ntchito yokha. Imagwira ntchito mogwirizana ndi ma neurotransmitters ena osiyanasiyana, mahomoni, ndi mankhwala, zomwe zimapangitsa kuti kuyanjana kumeneku kukhale kovuta kwambiri.

Komabe, pali zinthu zingapo zomwe zimayambitsa kusalinganika kwa dopamine:

Mikhalidwe yokhudzana ndi kuchepa kwa dopamine:

• Matenda Osazindikira Kwambiri (ADHD): Kafukufuku akusonyeza kuti anthu omwe ali ndi ADHD nthawi zambiri amakhala ndi dopamine yochepa.
• Matenda a Parkinson: Matendawa amapezeka pamene maselo enaake a muubongo omwe amapanga dopamine ayamba kuchepa mphamvu.
• Matenda a Miyendo Yosakhazikika (RLS): Matenda omwe amadziwika ndi kusakhazikika kwa miyendo, zomwe zimapangitsa kuti miyendoyo ikhale ndi chilakolako chosagonjetseka chofuna kusuntha miyendoyo.

Matenda okhudzana ndi kuchuluka kwa dopamine:

• Kusokonezeka maganizo: Mkhalidwe wamaganizo womwe umadziwika ndi kusangalala kwambiri, kusangalala kwambiri, komanso kuchita zinthu zambiri.
• Kunenepa Kwambiri: Kafukufuku wambiri wasonyeza kuti pali kugwirizana pakati pa dopamine regulation ndi kunenepa kwambiri.
• Chizolowezi: Dopamine imagwira ntchito yofunika kwambiri pa kudalira zinthu ndi makhalidwe monga kutchova juga.

Mikhalidwe yokhudzana ndi dopamine yotsika komanso yapamwamba:

• Schizophrenia: Iyi ndi matenda ovuta amisala. Zizindikiro zina, monga kuona zinthu molakwika kapena kuganiza molakwika, zitha kulumikizidwa ndi dopamine yochulukirapo m'madera enaake a ubongo, pomwe zizindikiro zina, monga kusowa chilimbikitso kapena kudzipatula, zitha kugwirizanitsidwa ndi milingo yochepa ya dopamine m'malo osiyanasiyana.

Ndi mankhwala ati omwe amagwirizana ndi dopamine?

Pali mankhwala osiyanasiyana omwe amapangidwira kuchepetsa kuchuluka kwa dopamine kapena kutsanzira ntchito yake. Tiyeni tifufuze motsogozedwa ndi Nirogi Lanka.

Kodi Dopamine Agonists ndi chiyani?

Mankhwala otchedwa dopamine agonists amagwira ntchito mofanana ndi dopamine yachilengedwe ya thupi lanu. Amamangirira ndi kulimbikitsa ma dopamine receptors muubongo, zomwe zimayambitsa yankho lofanana ndi pamene dopamine yanu imagwira ntchito pa maselo amitsempha.

Mankhwalawa amagwiritsidwa ntchito pochiza matenda monga Parkinson's disease, depression, Restless Legs Syndrome (RLS), ADHD, low libido, ndi hyperprolactinemia (kupanga kwambiri kwa hormone yotulutsa mkaka).

Zitsanzo zikuphatikizapo:

• Kwa Parkinson's: Pramipexole (Mirapex®), Ropinirole (Requip®), Rotigotine (Neupro®), Apomorphine HCl (KYNMOBI®).
• Kwa Matenda Ovutika Maganizo: Pramipexole (Mirapex®).
• Pa Kuchepa kwa Libido: Pramipexole (Mirapex®).
• Kwa Hyperprolactinemia: Bromocriptine (Parlodel®), Cabergoline (Dostinex®).

Kodi Otsutsa Dopamine Ndi Chiyani?

Mankhwala oletsa dopamine amagwira ntchito poletsa ma dopamine receptors muubongo, zomwe zimathandiza kuti dopamine isafike ku selo lotsatira la mitsempha. Mankhwala ambiri oletsa matenda amisala ali m'gulu ili.

Izi zimagwiritsidwa ntchito pochiza matenda a schizophrenia, matenda a bipolar, komanso zizindikiro za nseru ndi kusanza.

• Pa matenda a Schizophrenia: Aripiprazole (Abilify®), Risperidone (Risperdal®), Ziprasidone (Geodon®).
• Kwa Matenda a Bipolar: Risperidone, Olanzapine (Zyprexa®), Ziprasidone.
• Kwa nseru ndi kusanza: Metoclopramide (Reglan®), Droperidol (Inapsine®).

Kodi Dopamine Reuptake Inhibitors ndi chiyani?

Mankhwala oletsa kubwerezabwereza kwa dopamine amaletsa maselo amitsempha omwe adatulutsa dopamine kuti asayamwitsenso. Izi zimapangitsa kuti dopamine yambiri ipezeke muubongo kuti maselo amitsempha oyandikana nawo agwiritse ntchito.

Mankhwalawa amathandiza pochiza kuvutika maganizo ndi kugona tulo masana (narcolepsy), komanso angathandize kuchira ku zizolowezi monga kusuta fodya kapena kudya mopitirira muyeso.

• Kwa Matenda Ovutika Maganizo: Bupropion (Wellbutrin®).
• Kwa matenda a narcolepsy: Modafinil (Provigil).
• Chithandizo cha Kuledzera: Bupropion, Nomifensine, Benztropine (Cogentin), Mazindol.
• Kuletsa Kusuta: Bupropion.

Kodi Levodopa ndi chiyani?

Levodopa ndiye mankhwala ofunikira omwe amagwiritsidwa ntchito pochiza matenda a Parkinson. Mavuto oyenda mu Parkinson amayamba chifukwa cha kutayika kwa dopamine. Pofuna kuonetsetsa kuti Levodopa ikufika bwino muubongo, nthawi zambiri imaphatikizidwa ndi Carbidopa. Ikalowa muubongo, imasanduka dopamine.

Kodi ntchito ya dopamine ndi yotani pa chizolowezi cha mankhwala osokoneza bongo?

Kugwiritsa ntchito mankhwala osokoneza bongo kumasokoneza momwe maselo anu a muubongo amatumizira ndikulandira mauthenga. Zinthu zina monga chamba kapena heroin zimafanana ndi ma neurotransmitters achilengedwe. Zina, monga amphetamines kapena cocaine, zimayambitsa kutulutsidwa kwakukulu kwa dopamine kapena kuletsa kuyamwa kwake. Ngati inu kapena munthu amene mumamudziwa akuvutika, chonde funsani ogwira ntchito zadzidzidzi kapena pitani kuchipatala chapafupi nthawi yomweyo.

Zinthu zimenezi zimalimbitsa kwambiri "malo opatsa mphotho" muubongo wanu. Mukagwiritsa ntchito mankhwala osokoneza bongo nthawi zonse, ziwalo zina za ubongo wanu zimakhala zosagwira ntchito, zomwe zimapangitsa kuti zikhale zovuta kusangalala ndi china chilichonse. Nthawi yomweyo, mumapeza kuti mukufunikira kuchuluka kwa mankhwalawa kuti mupeze zotsatira zomwezo. Kuphatikiza apo, madera ena a ubongo wanu amakhala okhudzidwa kwambiri ndi kusasangalala—monga nkhawa ndi kusakhazikika—komwe kumachitika pamene mankhwalawa atha. Izi zimakupangitsani kuti mugwiritsenso ntchito mankhwalawa kuti muthawe malingaliro oipa amenewo. Mwachidule, chizolowezi ndi vuto lalikulu lomwe limayamba kudzera m'njira zosiyanasiyana zovuta.

Asayansi tsopano akukhulupirira kuti ntchito ya dopamine sikuti imangopangitsa munthu kukhala ndi chisangalalo; m'malo mwake, imagwira ntchito ngati chizindikiro cholimbikitsa chomwe chimathandiza ubongo wanu kukumbukira zochitika zabwino kotero kuti mukulimbikitsidwa kuzibwereza. Mankhwala osokoneza bongo akayambitsa kuchuluka kwa dopamine, ubongo wanu "umaphunzira" bwino kuyika zomwe mwakumana nazo. Ubongo wanu umayamba kulumikiza kugwiritsa ntchito mankhwala osokoneza bongo ndi chizolowezi chilichonse, chizindikiro cha chilengedwe, ndi machitidwe omwe munkachita panthawiyo. Ichi ndichifukwa chake, ngakhale mutakhala oyera kwa nthawi yayitali, kubwerera kumalo komwe mudagwiritsa ntchito mankhwala osokoneza bongo kungayambitse chilakolako chachikulu.

Kodi mungawonjezere bwanji kuchuluka kwa dopamine mwachilengedwe?

Mungayesere kugwiritsa ntchito zizolowezi zomwe zimathandiza kuwongolera kuchuluka kwa dopamine m'thupi. Komabe, chonde dziwani kuti kafukufuku wowonjezereka akufunika kuti mumvetse bwino momwe zakudya zinazake zimakhudzira mwachindunji ma neurotransmitters monga dopamine.

• Idyani zakudya zokhala ndi magnesium ndi tyrosine. Izi ndi zinthu zofunika kwambiri popanga dopamine. Tyrosine ndi amino acid yomwe thupi lanu limayamwa ndikuyitumiza ku ubongo, komwe imasanduka dopamine. Zakudya zomwe nthawi zambiri zimatchulidwa kuti zithandizire kupanga dopamine ndi monga: nkhuku, amondi, maapulo, ma avocado, nthochi, beets, chokoleti (makamaka chokoleti chakuda), ndiwo zamasamba zobiriwira, tiyi wobiriwira, nyemba za lima, oatmeal, malalanje, okra, mbewu za sesame ndi dzungu, tomato, turmeric, vwende, ndi tirigu.
• Chitani zinthu zomwe zimakupangitsani kukhala osangalala komanso omasuka. Zinthuzi zimakhulupirira kuti zimathandiza kuti dopamine ichuluke. Zitsanzo zake ndi izi: kuchita masewera olimbitsa thupi nthawi zonse, kusinkhasinkha, yoga, kupatsidwa masaji, kusewera ndi chiweto, kukhala ndi nthawi m'chilengedwe, kapena kuwerenga buku labwino.

Uthenga Wopita Nawo Kunyumba

Dopamine imagwira ntchito ngati neurotransmitter komanso mahomoni. Imagwira ntchito yofunika kwambiri m'machitidwe ambiri ofunikira a thupi lanu, makamaka pakuyenda, kukumbukira, kusangalala, komanso chilimbikitso. Kusinthasintha kwa kuchuluka kwa dopamine kumalumikizidwa ndi matenda osiyanasiyana amisala komanso matenda amitsempha.

Dopamine ndi yovuta kwambiri. Ofufuza akufufuzabe momwe imagwirira ntchito ndi ma neurotransmitters ena, mahomoni, ndi mankhwala muubongo, komanso momwe kuyanjana kumeneku kumakhudzira thanzi lanu lonse.

Ngati mukuganiza kuti mukukumana ndi zizindikiro za kuchepa kapena kuchuluka kwa dopamine, chonde funsani dokotala wanu. Dokotala wanu akhoza kuwunika zizindikiro zanu, kuchita mayeso ofunikira, ndikupereka dongosolo loyenera la chithandizo ngati muli ndi vuto lachipatala. Kumbukirani, musayese kudziyesa nokha kapena kudzipatsa mankhwala, makamaka pankhani ya ntchito zovuta za mitsempha.

Mawu Ofunika: Dopamine, Neurotransmitter, Hormone, Ubongo, Thanzi la Maganizo, Matenda a Parkinson, Kuledzera