Kodi khungu lanu ndi maso anu oyera akusanduka achikasu? Tiyeni tiphunzire zambiri za matenda a Dubin-Johnson!

Kodi munayamba mwazindikirapo kuti khungu lanu kapena maso anu oyera akuoneka ngati achikasu pang'ono? Kapena munayamba mwazindikirapo kuti mkodzo wanu ndi wachikasu wakuda kuposa masiku onse? Ngati mukukumana ndi zinthuzi, chifukwa chimodzi chomwe chingakhalepo ndi matenda osowa koma osaopsa kwambiri otchedwa Dubin-Johnson syndrome . Chifukwa chake, tiyeni tikambirane za izi mwatsatanetsatane, mwachidule.

Kodi Dubin-Johnson Syndrome ndi chiyani?

Mwachidule, matenda a Dubin-Johnson ndi matenda a majini omwe amakhudza chiwindi chathu. Chomwe chimachitika pamenepa ndi chakuti chinthu chachikasu chotchedwa bilirubin, chomwe chimapangidwa m'thupi lathu, chimasonkhana m'malo motulutsidwa m'thupi moyenera. Tsopano mwina mukudabwa kuti bilirubin ndi chiyani. Patapita nthawi, nthawi yawo ya moyo ikatha, maselo ofiira a m'magazi athu amasweka. Pamenepo ndi pomwe bilirubin iyi imapangidwa. Nthawi zambiri, bilirubin iyi iyenera kutulutsidwa m'chiwindi chathu pamodzi ndi ndulu ndikutulutsidwa m'thupi ngati zinyalala. Komabe, izi sizichitika bwino m'thupi la munthu yemwe ali ndi matenda a Dubin-Johnson. Chifukwa chake, bilirubin imasonkhana m'chiwindi ndi m'magazi, zomwe zimayambitsa zizindikiro monga jaundice . Pamenepo khungu ndi zoyera za m'maso zimakhala zachikasu.

Ndani amene akukhudzidwa kwambiri ndi vutoli?

Matenda a Dubin-Johnson ndi matenda a majini , kotero amatha kukhudza aliyense, pa msinkhu uliwonse. Kuti mulandire matendawa, makolo anu onse ayenera kukupatsirani jini. Izi zimatchedwa cholowa cha autosomal recessive . Mwachitsanzo, ngati mulandira jini kuchokera kwa kholo limodzi lokha, simudzawonetsa zizindikiro, koma mudzakhala wonyamula jini. Izi zikutanthauza kuti mutha kupatsira jini kwa ana anu.

Kodi vutoli ndi lofala bwanji?

Palibe ziwerengero zenizeni za momwe izi zilili zofala, koma zimachitika kwambiri kwa anthu okhala m'maiko monga Iran, Iraq, Morocco, ndi Japan. Akuti pafupifupi munthu m'modzi pa anthu 1,300 m'maiko amenewo akhoza kukhala ndi vutoli.

Kodi matenda a Dubin-Johnson amakhudza bwanji thupi langa?

Matenda a Dubin-Johnson amayamba chifukwa cha kuchulukana kwa bilirubin yachikasu m'chiwindi mwanu. Izi ndi zomwe zimapangitsa kuti khungu lanu ndi zoyera za maso anu zizioneka zachikasu. Nthawi zina, mukakhala m'nyumba komanso mumdima wochepa, simungazindikire chikasu ichi. Komabe, pamalo owala bwino, monga padzuwa, chikasu ichi chimawonekera kwambiri. Nthawi zambiri, chinthu choyamba chomwe mumazindikira pa chikasu ichi ndi nkhope.Kenako imatha kufalikira ku ziwalo zina za thupi, monga pachifuwa ndi m'mimba. Mukayang'ana pagalasi, ngati mutatsegula pakamwa panu ndikuyang'ana pansi pa lilime lanu, mutha kuwona kuti lasanduka lachikasu pamenepo.

Kodi zizindikiro za izi ndi ziti?

Anthu ambiri omwe amapezeka ndi matenda a Dubin-Johnson amakhala ndi zizindikiro zazikulu za jaundice, zomwe zimachitika chifukwa cha kuchuluka kwa bilirubin m'chiwindi. Izi zikutanthauza:

• Khungu lanu limakhala lachikasu komanso loyera m'maso mwanu.
• Kusintha kwa mtundu wa mkodzo wanu (kusintha kukhala wachikasu chakuda kapena bulauni).

Nthawi zina, thupi likakhala ndi nkhawa, mwachitsanzo, mukakhala ndi matenda ena, panthawi ya mimba, kapena ngati mukugwiritsa ntchito mapiritsi oletsa kubereka (mankhwala oletsa kubereka), mtundu wachikasu uwu ukhoza kuwonjezeka.

Kuwonjezera pa izi, zizindikiro zina zazing'ono zingachitike, koma nthawi zambiri sizimakhala zoopsa kwambiri:

• Kumva kutopa ndi `(Kutopa)`.
• Kupweteka pang'ono m'mimba (Ululu wa m'mimba).

Chofunika kwambiri ndichakuti matenda a Dubin-Johnson ndi matenda abwino. Izi zikutanthauza kuti sadzawononga moyo wanu kwambiri.

Ngati muchita mayeso ena, mutha kuwona zinthu monga izi:

• Chiwindi chanu chili ndi zinthu zina zomwe zimachipangitsa kuoneka chakuda (izi zimayesedwa potenga chidutswa chaching'ono cha minofu kuchokera ku chiwindi - chimatchedwa `Liver Biopsy` ).
• Chiwindi chikhoza kukulirakulira pang'ono ( Hepatomegaly ).

Kodi n’chiyani chimayambitsa matenda a Dubin-Johnson?

Chifukwa chachikulu cha matenda a Dubin-Johnson ndi kusintha kwa majini a `ABCC2`. Jini iyi ya `ABCC2` imapanga puloteni yomwe imathandiza maselo athu kuchotsa zinyalala. Makamaka, puloteni iyi imathandiza maselo a chiwindi kuchotsa bilirubin (chinthu chachikasu chomwe chatsala kuchokera ku kuwonongeka kwa maselo ofiira a magazi) ndikuchitulutsa ngati ndulu (madzimadzi omwe amathandiza kugaya chakudya).

Choncho, ngati muli ndi matenda a Dubin-Johnson, thupi lanu silingathe kuchotsa bwino zinyalala izi zotchedwa bilirubin m'maselo anu. Zotsatira zake, zinthu monga bilirubin zimasonkhana m'thupi lanu (izi zimatchedwa hyperbilirubinemia ). Ndicho chifukwa chake zizindikiro monga jaundice zimawonekera.

Kodi matenda a Dubin-Johnson amawapeza bwanji?

Dokotala wanu adzayamba wakuyang'anani, wakufunsani za zizindikiro zanu, ndikupeza ngati pali wina m'banja mwanu amene wakhalapo ndi matenda ofanana ndi anu kale (mbiri ya matenda a m'banja).

Kenako, adzayitanitsa mayeso ena angapo kuti atsimikizire matendawa. Izi zingaphatikizepo:

• Mayeso ojambulira (monga X-ray , ultrasound scan ) kuti muwone chiwindi chanu.
• Kuyezetsa magazi (makamaka mayeso a bilirubin )chimodzi).
• Kuyesa mkodzo .
• Mwina mayeso omwe amatengedwa chidutswa chaching'ono cha chiwindi ( `Chiwindi cha Biopsy` ).

Ngati mayeso a bilirubin akusonyeza kuti bilirubin m'magazi mwanu ndi yokwera kwambiri, zikutanthauza kuti muli ndi vuto lotchedwa hyperbilirubinemia (kuchuluka kwa bilirubin m'magazi). Ngati zizindikiro zanu zikupitirira, dokotala wanu angakuwuzeni kuti muyesedwe magazi m'majini kuti mupeze jini yomwe ikuyambitsa zizindikiro zanu. Iyi ndiyo njira yokhayo yotsimikizira kuti muli ndi matenda a Dubin-Johnson.

Kodi mankhwala ochizira izi ndi otani?

Nkhani yabwino ndi yakuti anthu ambiri omwe amapezeka ndi matenda a Dubin-Johnson safunika chithandizo chilichonse. Izi zili choncho chifukwa si vuto lalikulu. Komabe, ngati pakufunika chithandizo, nthawi zambiri chimakhala cha vuto lina kapena njira ina yomwe imapangitsa kuti milingo ya bilirubin yanu ikwere. Mwachitsanzo, ngati muli ndi chimfine, dokotala wanu angakuuzeni kuti mumwe madzi ambiri ndikupumula. Kapena, ngati mankhwala omwe mukumwa akukupangitsani kuti zizindikiro zanu ziwonjezeke, dokotala wanu angakulangizeni kuti musiye kumwa mankhwalawo.

Kodi n’chiyani chingapangitse kuti zizindikiro za matenda a Dubin-Johnson zikhale zovuta kwambiri?

Zizindikiro za jaundice zomwe zimayambitsa matenda a Dubin-Johnson zimatha kukhalapo kwa moyo wonse. Komabe, zizindikirozi zitha kukulirakulira ngati:

• Ngati mumwa mowa.
• Ngati mukumwa mapiritsi oletsa kubereka.
• Ngati pali matenda.
• Ngati muli ndi pakati.

Ngati mukuona kuti zizindikiro zanu zikuipiraipira, lankhulani ndi dokotala wanu za njira zina zothandizira zomwe zingakuthandizeni kupeza mpumulo.

Kodi matenda a Dubin-Johnson angapewedwe?

Popeza ndi matenda a majini, sitingathe kuletsa matenda a Dubin-Johnson kuti asakule. Komabe, ngati mukukonzekera kukhala ndi mwana ndipo mukufuna kudziwa zoopsa zomwe mwana wanu angakhale nazo pa matenda a majini, mutha kulankhula ndi dokotala wanu za kuyezetsa majini kapena upangiri wa majini .

Ngati ndili ndi matenda a Dubin-Johnson, kodi ndiyenera kuyembekezera chiyani?

Chiyembekezo cha anthu omwe apezeka ndi matenda a Dubin-Johnson ndi chabwino kwambiri. Palibe mankhwala, ndipo nthawi zambiri chithandizo sichifunika, ndipo zizindikiro zake zimathetsedwa. Chofunika kwambiri, vutoli silikhudza moyo wa munthu.

Ndiyenera kupita kwa dokotala nthawi yanji?

Ngati zizindikiro za matenda anu a Dubin-Johnson zikuipiraipira, makamaka ngati matenda anu a chikasu (jaundice) akuyambitsa zizindikiro zofanana ndi chimfine, onani dokotala wanu. Mwachitsanzo:

• Kupweteka m'mimba .
• Malungo .
• Kutopa .
• Kusanza kapena kusanza .

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Mungathe kufunsa dokotala wanu mafunso monga awa:

• Kodi zizindikiro zanga zimafunika chithandizo?
• Kodi mwana wanga adzalandira vutoli?
• Kodi ndiyenera kuchita chiyani ngati ndikumva kudwala chifukwa cha zizindikiro zanga?

Kodi pali kusiyana kotani pakati pa Dubin-Johnson syndrome ndi Rotor syndrome?

Matenda a Dubin-Johnson ndi matenda a Rotor onse ndi matenda a majini. Onse ali ndi zizindikiro zofanana, monga jaundice. Komabe, kusiyana kwakukulu pakati pa matenda awiriwa ndi chifukwa chake.

Matenda a Dubin-Johnson amayamba chifukwa cha kusintha kwa majini a `ABCC2`. Komabe, matenda a Rotor amayamba chifukwa cha kusintha kwa majini a `SLCO1B1` ndi `SLCO1B3` .

Chinthu china chofunika kudziwa ndi chakuti Rotor Syndrome ingakhudze kwambiri momwe thupi la munthu limagwiritsira ntchito mankhwala enaake. Chifukwa chake, ngati inu kapena mwana wanu muli ndi Rotor Syndrome, ndikofunikira kwambiri kudziwitsa dokotala wanu musanapereke mankhwala enaake.

Kuphatikiza apo, Rotor Syndrome siimayambitsa kusintha kwa mtundu wa chiwindi. Komabe, chiwindi cha anthu omwe ali ndi Dubin-Johnson Syndrome chimawoneka chakuda .

Ndizachibadwa kukhala ndi nkhawa khungu lanu kapena la mwana wanu likasanduka lachikasu. Ngakhale kuti matenda a jaundice ndi ofala mwa makanda obadwa kumene, matenda a jaundice omwe amayamba chifukwa cha matenda a Dubin-Johnson ndi matenda osatha komanso osatha kwa moyo wonse.

Pomaliza, zinthu zoti muzikumbukira (Uthenga Wopita Nawo Kunyumba)

Kotero, tsopano mukudziwa zambiri zokhudza matenda a Dubin-Johnson. Musadandaule, si vuto lalikulu. Dokotala wanu adzakufotokozerani chithandizo chomwe chikufunika kuti muchepetse chikasu cha maso ndi khungu lanu, kapena ngati mukupeza zizindikiro zina. Chofunika kwambiri ndikulankhula ndi dokotala wanu za zizindikiro zanu nthawi zonse ndikuonetsetsa kuti muli ndi thanzi labwino. Mutha kukhala ndi moyo wabwinobwino komanso wosangalala ndi vutoli.

Matenda a Dubin -Johnson, malungo achikasu, chiwindi, bilirubin, matenda a majini, chikasu cha khungu, jaundice