Kodi mukudziwa za Giant Cell Tumor (GCT)? Tiyeni tikambirane za izi!

Kodi munayamba mwamvapo kupweteka pang'ono, kutupa pang'ono, kapena chotupa m'dzanja lanu, makamaka pa bondo lanu, m'chiuno, paphewa, kapena pachikhatho? Ngati ndi choncho, ndi bwino kuda nkhawa pang'ono. Chifukwa chikhoza kukhala chizindikiro cha vuto lomwe tikambirane lero lotchedwa 'Giant Cell Tumor (GCT)'. Musadandaule, tikambirana izi mwatsatanetsatane.

Kodi chotupa chachikulu cha selo (GCT) kwenikweni n'chiyani?

Mwachidule, ``Giant Cell Tumor (GCT)`` ndi chotupa chosakhala khansa (ndipo nthawi zambiri chimakhala chosaopsa) . Nthawi zambiri chimapangika kumapeto kwa mafupa ataliatali m'thupi lanu. Makamaka, amapezeka kwambiri pansi pa fupa la ntchafu yanu ``femur`` kapena pamwamba pa fupa lanu la shin ``tibia``, lomwe lili mozungulira bondo . Komabe, amathanso kupangika m'malo monga m'chiuno, phewa, dzanja, ndi mchira. Izi zimatchedwanso ``Osteoclastomas```.

Matendawa otchedwa `(GCT)` ndi osowa kwambiri . Amapezeka mwa munthu m'modzi kapena awiri pa anthu 100,000 aliwonse. Komabe, pakati pa zotupa zomwe si khansa zomwe zimayambira m'mafupa, `(GCT)` ndi pakati pa 15% ndi 21% ya milandu yonse.

Nthawi zina zotupa zazikuluzikuluzi sizimakula m'mafupa, koma m'minofu yofewa yozungulira malo olumikizirana mafupa. Kenako zimatchedwa Tenosynovial giant cell tumors.

Chofunika kwambiri ndichakuti ngakhale kuti `(Giant Cell Tumors)` izi si khansa, zimatha kukula mofulumira ndikuwononga minofu yathanzi yozungulira . Komanso, zili ndi mwayi waukulu `(wobwerezabwereza)` ngakhale mutalandira chithandizo. Ichi ndichifukwa chake ndikofunikira kuwona dokotala mwachangu ngati muwona zizindikiro zilizonse za chotupa chonga ichi.

Kodi zizindikiro za izi ndi ziti? Onani ngati muli nazonso...

Chizindikiro chachikulu komanso chodziwika bwino cha chotupa chachikulu cha maselo (GCT) ndi ululu . Ngakhale ululuwo ukhoza kukhala wochepa poyamba, umawonjezeka pamene chotupacho chikukula. Tangoganizirani, mutadzuka m'mawa wina ndikumva kupweteka pang'ono pafupi ndi bondo lanu. Poyamba, mumanyalanyaza. Koma patapita kanthawi, ululuwo umawonjezeka, ndipo mukamaukhudza, umamveka ngati chotupa chaching'ono. Pamenepo ndi pamene mumaopa pang'ono, eti?

Pali zizindikiro zina zingapo:

• Chotupa kapena kutupa komwe kumawonekera m'dzanja kumaonekera m'dera limenelo.
• Kulephera kusuntha bwino cholumikizira pamalo pomwe pali chotupa kumatanthauza kuti kuyenda kwa cholumikizira kumakhala kochepa.
• Kupweteka kwa mafupa , makamaka posuntha mafupa.
• Kutupa .
• Chotupacho chingafooketse mafupa ndikupangitsa kuti mafupa asweke .

Ngati muli ndi chimodzi kapena zingapo mwa zizindikirozi, chonde funsani upangiri kwa dokotala.

N’chifukwa chiyani zinthu ngati zimenezi zimachitika? Chifukwa chake n’chiyani?

Ndipotu, ofufuza zachipatala sakudziwabe chomwe chimayambitsa matenda a khansa ya maselo akuluakulu. Komabe, anthu ena omwe ali ndi vutoli apezeka kuti ali ndi kusintha kwina (kusintha kwa majini) m'majini awo. Komabe, pakadali pano akukhulupirira kuti ichi si chinthu chobadwa nacho, kapena chinthu chomwe chimayamba chifukwa cha malo omwe mumakhala kapena moyo wanu .

Kodi pali zinthu zina zomwe zingakubweretsereni mavuto?

Inde, nthawi zina mwayi wokhala ndi `(GCT)` uwu ukhoza kuwonjezeka pang'ono:

• Ngati muli ndi vuto lotchedwa `(Hyperparathyroidism)` (lomwe limapanga mahomoni ambiri a parathyroid), `(GCT)` limatha kuchitika m'malo angapo m'thupi lanu.
• Kawirikawiri, anthu omwe ali ndi matenda a mafupa otchedwa ``Paget's disease of the bone'' amathanso kudwala matenda akuluakulu a maselo amenewa.

Kodi izi zingakhale zoopsa? Kodi mavuto ake ndi otani?

Ngakhale kuti zotupa izi si khansa, nthawi zambiri, ndiko kuti, nthawi zambiri, zotupa zazikuluzikulu za maselo zimatha "kufalikira" mpaka m'mapapo . Komabe, sizili ngati khansa imafalikira, ndipo ngakhale itafalikira motere, nthawi zambiri siimakhala pachiwopsezo.

Kawirikawiri, mwa anthu pafupifupi 4% omwe ali ndi GCT, zotupazi zimatha kukhala khansa (zoopsa) . Chifukwa chake, dokotala wanu adzayang'anira vuto lanu nthawi zonse kuti awone ngati pali kusintha kulikonse koopsa mu chotupacho. Ichi ndichifukwa chake ndikofunikira kukaonana ndi dokotala wanu nthawi zonse ndikupeza upangiri.

Kodi madokotala amapeza bwanji izi?

Kuti mutsimikizire ngati muli ndi chotupa chachikulu cha selo (GCT) , biopsy imachitika. Izi zimaphatikizapo kutenga chitsanzo chaching'ono cha minofu kuchokera ku chotupacho ndikuchiyang'ana pansi pa maikulosikopu. Kuyesaku kumachitika ndi katswiri wa matenda, dokotala yemwe ndi katswiri wa minofu. Iye adzayang'ana ngati maselowo ndi "maselo akuluakulu," kapena ali ndi mawonekedwe ofanana ndi a GCT.

Kuphatikiza apo, mayeso ojambulira zithunzi ngati awa angachitike kuti aone chotupa mkati mwa thupi lanu:

• X-ray : Yang'anani momwe mafupa alili.
• Kujambula kwa CT : Onani kukula ndi mawonekedwe a chotupacho mwatsatanetsatane.
• MRI : Imafufuza minofu yofewa, mafuta a m'mafupa, ndi zina zotero.
• Kufufuza mafupa : Yang'anani ngati pali mavuto ena m'mafupa.
• Kujambula kwa PET : Kuti muwone ngati pali zizindikiro zosonyeza kuti chotupacho chikusintha kukhala khansa.

Mayeso onsewa amachitika kuti amvetsetse bwino vuto lanu ndikupeza chithandizo chabwino kwambiri.

Chabwino, tsopano chithandizo cha izi ndi chiyani?

Matenda akuluakulu a maselo nthawi zambiri amachiritsidwa ndi opaleshoni . Dokotala amachotsa chotupacho m'fupa (curettage). Kenako, chogwirira cha mafupa chimayikidwa pamalo opanda kanthu.Fupa limalimbikitsidwa polumikiza (chidutswa cha fupa chotengedwa kuchokera kwina kapena chinthu chopangidwa). Nthawi zina, ngati chotupacho ndi chachikulu kwambiri, fupa lonse lomwe lili ndi chotupacho lingafunike kuchotsedwa. Zikatero, cholumikizira chopangidwa kapena fupa "prosthesis" chingaikidwe m'malo mwake.

Komabe, ngati opaleshoni singathe kuchotsa chotupa chonse, kapena ngati opaleshoniyo ndi yoopsa, pali njira zina zochiritsira popanda opaleshoni. Izi zikuphatikizapo:

• Denosumab (Denosumab - Xgeva®) : Iyi ndi mtundu wa mankhwala otchedwa monoclonal antibody. Imafooketsa chotupa ndikulimbitsa fupa lozungulira.
• Kutulutsa magazi m'thupi : Izi zimaphatikizapo kutseka mitsempha yamagazi yomwe imapereka magazi ku chotupacho. Izi zimachotsa magazi m'chotupacho ndipo zimapangitsa kuti chife pang'onopang'ono.
• Chithandizo cha ablation : Izi zimagwiritsa ntchito mphamvu ngati microwave kuti ziwononge chotupacho.
• Chithandizo cha radiation : Izi zimagwiritsa ntchito ma X-ray amphamvu kwambiri kuti achepetse chotupa ndikuwononga maselo.

Dokotala wanu adzasankha chithandizo chomwe chili chabwino kwa inu.

Kodi zimatenga nthawi yayitali bwanji kuti munthu achire pambuyo pa chithandizo?

Nthawi yomwe imatenga kuti muchire imadalira chithandizo chomwe mwalandira. Ngati munachitidwa opaleshoni, muyenera kuvala mabandeji kwa milungu ingapo pamene bala likuchira. Mungafunikenso kugwiritsa ntchito ndodo panthawiyo. Ngati muli ndi chipangizo chopangira, muyenera kugwira ntchito ndi katswiri wa zamaganizo kuti muzolowere.

Dokotala wanu adzakufotokozerani zonsezi, kotero palibe chodetsa nkhawa.

Kodi palibe njira yoletsera izi? Kodi ubwino wodziwa pasadakhale ndi wotani?

Popeza chifukwa chenicheni cha matenda a khansa ya maselo akuluakulu sichikudziwika, pakadali pano palibe njira yowaletsera kuti asakule . Komabe, chinthu chabwino kwambiri chomwe mungachite ndikupempha upangiri wa dokotala mukangoona zizindikiro . Ngati muwona kupweteka, kutupa, kapena chotupa m'fupa kapena malo olumikizirana mafupa anu, musachinyalanyaze ndipo pitani kwa dokotala nthawi yomweyo. Ngati matenda monga `(GCT)` apezeka msanga, ndi osavuta kuchiza ndipo amakhala ndi zovuta zochepa.

Ngati n'kotheka, ndi bwino kuonana ndi dokotala yemwe ndi katswiri wa khansa yokhudzana ndi mafupa, katswiri wa khansa ya mafupa .

Ndiye mumakhala bwanji ndi vutoli? Kodi muyenera kupita kwa dokotala nthawi zonse?

Ziphuphu zazikulu za maselo sizimaika moyo pachiswe nthawi zambiri. Komabe, zimatha kuwononga mafupa ndi minofu yozungulira, ndichifukwa chake chithandizo cha msanga chili chofunikira.

Nkhani yabwino ndi yakuti ngati ziwalo zonse za chotupacho zichotsedwa opaleshoni, vutoli likhoza kuchiritsidwa kwathunthu. Komabe, GCT ndi mtundu wovuta pang'ono ndipo ukhoza kumeranso .

Pambuyo pa chithandizo, dokotala wanu adzakuyang'anani nthawi zonse kuti akakuwoneni nthawi yotsatira . Izi ndi kuonetsetsa ngati chotupacho chabwerera. Nthawi zambiri, chotupachi chimabwereranso mkati mwa zaka ziwiri kapena zisanu zoyambirira mutachita opaleshoni. Komabe, mungafunike kufufuzidwa nthawi zonse pa moyo wanu wonse. Dokotala wanu adzakuuzani kangati komwe muyenera kubwera kudzafufuzidwa.

Kodi muyenera kukaonananso ndi dokotala liti?

Ngati muli ndi zizindikiro zilizonse zoti chotupa chachikulu cha selo lanu chikubwerera, pitani kwa dokotala nthawi yomweyo. Dziwani ululu uliwonse watsopano wa mafupa kapena mafupa kapena kutupa. Ngakhale dokotala wanu atakuyang'anani nthawi zonse, ngati muwona kusintha kulikonse, ndi bwino kuyimbira dokotala wanu nthawi yomweyo osadikira nthawi yanu yotsatira.

Mukufuna kufunsa dokotala chiyani?

Mukapita kwa dokotala, ndi bwino kufunsa mafunso awa:

• Kodi chotupa ichi ndi champhamvu bwanji?
• Kodi ndi njira ziti zochiritsira zomwe ndili nazo?
• Kodi ubwino ndi zoopsa zotani zokhudzana ndi chithandizo chilichonse mwa izi ndi ziti?
• Kodi pali mwayi wotani kuti chotupa chachikulu ichi cha selo chidzabwerenso pambuyo pa chithandizo?
• Kodi ndiyenera kubwera kangati kudzakumana ndi dokotala wotsatira ?

Kudziwa mayankho a mafunso awa kudzakuthandizani kumvetsetsa bwino vutoli ndikupangitsa kuti zikhale zosavuta kupirira chithandizo.

Ndiye, ndi zinthu ziti zofunika kwambiri zomwe tiyenera kukumbukira kuchokera munkhaniyi?

Kungoti chotupa chachikulu cha maselo (GCT) ndi "choyipa" sizikutanthauza kuti sichidzabweretsa vuto lililonse. Ngati sichidzachiritsidwa, ma GCT awa akhoza kuwononga mafupa anu kwambiri.

Chabwino kwambiri ndichakuti mutha kuwachotsa ndi opaleshoni kuti muchotse zotsalira zonse za chotupacho. Komabe, izi `(GCT)` zimakhala zolimba pang'ono ndipo zimatha kumeranso. Ndicho chifukwa chake dokotala wanu adzakuyang'anirani mosamala mukalandira chithandizo. Kuchotsa chotupacho chikadali chaching'ono kungalepheretse kuwonongeka kwa mafupa kwa nthawi yayitali.

Choncho, ngati muli ndi zizindikiro izi, musazengereze kupita kwa dokotala ndikupeza upangiri. Chithandizo choyambirira ndiyo njira yabwino kwambiri yopezera moyo wathanzi!

` Giant Cell Tumor, GCT, osteoclastoma, chotupa chosaopsa, chotupa cha mafupa, kupweteka kwa mafupa, chithandizo cha chotupa