Kodi kuthamanga kwa magazi anu sikutsika ngakhale mutamwa mankhwala? Tiyeni tiphunzire za hyperaldosteronism.

Kodi nthawi zina mumadabwa kuti, 'N'chifukwa chiyani kuthamanga kwa magazi anga sikutsika ngakhale nditamwa mankhwala?'? Anthu ena ali ndi vuto lomweli. Nthawi zina zimakhala zovuta kuwongolera kuthamanga kwa magazi awo, ngakhale mutamwa mankhwala. Nthawi zina ngati izi, tiyenera kuganizira ngati pangakhale chifukwa chenicheni. Lero, tikambirana za vuto lomwe nthawi zina limakhala lovuta kulizindikira, koma limatha kuchiritsidwa ngati litachiritsidwa bwino. Ndi hyperaldosteronism .

Kodi Hyperaldosteronism ndi chiyani?

Mwachidule, hyperaldosteronism imachitika pamene ma adrenal glands anu amatulutsa mahomoni ambiri otchedwa aldosterone . Taganizirani izi, aldosterone ili ngati injiniya wamng'ono amene amalamulira kuthamanga kwa magazi athu. Zimathandiza kuti kuthamanga kwa magazi athu kukhale pamlingo woyenera mwa kuwongolera kuchuluka kwa potaziyamu ndi sodium m'matupi athu.

Tsopano mwina mukudzifunsa kuti, 'Kodi ma adrenal glands awa ndi chiyani?' Awa ndi mbali ya dongosolo lathu la endocrine . Ali ngati mafakitale ang'onoang'ono omwe amapanga mahomoni osiyanasiyana omwe matupi athu amafunikira kuti agwire ntchito tsiku ndi tsiku. Tili ndi ma adrenal glands awiriwa, omwe kwenikweni amakhala pamwamba pa impso zathu, ngati chivundikiro.

Kodi mitundu ya hyperaldosteronism ndi iti?

Pali mitundu iwiri ikuluikulu ya hyperaldosteronism.

1. Matenda oyamba a Hyperaldosteronism: Nthawi zina amatchedwa Conn's syndrome . Chomwe chimachitika apa ndichakuti pali vuto ndi ma adrenal glands anu, zomwe zimapangitsa kuti apange aldosterone yochuluka. Taganizirani ngati pali vuto mkati mwa fakitale ndipo akupanga zinthu zambiri.

2. Secondary Hyperaldosteronism: Ili si vuto ndi ma adrenal glands. Ndi vuto linalake m'thupi lanu lomwe limapangitsa kuti ma adrenal glands azilimbikira ndikuyamba kupanga aldosterone yambiri. Izi zikutanthauza kuti fakitale ikugwira ntchito nthawi yayitali chifukwa cha mphamvu yakunja.

Mulimonsemo, zotsatira zake ndi zakuti kuchuluka kwa aldosterone m'magazi mwanu kumawonjezeka, zomwe zimapangitsa kuti kuthamanga kwa magazi kukwere (hypertension) komanso kuchuluka kwa potaziyamu m'magazi mwanu kuchepe. Kuchepa kwa potaziyamu kumeneku kumatchedwa hypokalemia .

Ndani amene amakhudzidwa kwambiri ndi vutoli? Kodi ndi lofala bwanji?

Hyperaldosteronism imapezeka kwambiri mwa anthu azaka zapakati pa 30 ndi 50.Komanso, vutoli ndi lofala pang'ono pakati pa akazi kuposa amuna.

N'zovuta kwa ofufuza kunena momwe izi zimachitikira kawirikawiri, chifukwa nthawi zina sizimadziwika bwino. Koma kafukufuku wina akusonyeza kuti pakati pa 5% ndi 10% ya anthu omwe ali ndi kuthamanga kwa magazi akhoza kukhala ndi vuto lalikulu la hyperaldosteronism. Akatswiri akuti anthu okwana 25% omwe ali ndi kuthamanga kwa magazi kosamva mankhwala akhoza kukhala ndi vutoli. Ndiye, si zachilendo, eti?

Kodi zizindikiro za Hyperaldosteronism ndi ziti?

Zizindikiro za hyperaldosteronism zimatha kusiyana malinga ndi munthu, kutengera kuopsa kwa vutoli. Anthu ena sangakhale ndi zizindikiro zilizonse , makamaka ngati vutoli silili lalikulu kwambiri.

Komabe, chizindikiro chachikulu komanso chodziwika bwino cha vutoli ndi kuthamanga kwa magazi (kuthamanga kwa magazi) , makamaka kuthamanga kwa magazi komwe sikungatheke kuthetsedwa mosavuta ngakhale ndi mankhwala.

Kuphatikiza apo, ngati mukukumana ndi zizindikiro zina, nthawi zambiri zimayambitsidwa ndi kuthamanga kwa magazi pang'ono mpaka kwakukulu komanso/kapena kuchepa kwa potaziyamu m'magazi (hypokalemia).

Zizindikiro zomwe zingachitike chifukwa cha kuthamanga kwa magazi (kuthamanga kwa magazi):

• Mutu
• Chizungulire
• Kusintha kwa masomphenya
• Kuvuta kupuma

Zizindikiro zomwe zingachitike chifukwa cha kuchepa kwa potaziyamu m'magazi (hypokalemia):

• Kufooka kwa minofu - Nthawi zina, vuto lofanana ndi kufooka kwakanthawi lingachitike.
• Kugwedezeka kwa minofu kapena kugwedezeka (Kugwedezeka kwa minofu)
• Kumva kuwawa ndi dzanzi
• Kutopa
• Ludzu lalikulu (izi zimatchedwa polydipsia)
• Kukodza pafupipafupi

Tsopano mukumvetsa, chifukwa zizindikiro zina izi ndizofala m'matenda ena, nthawi zina zimakhala mochedwa kuzindikira izi.

Kodi n’chiyani chimayambitsa izi?

Zomwe zimayambitsa hyperaldosteronism zimasiyana malinga ndi kuti ndi yoyamba kapena yachiwiri. Tiyeni tiwone momwe zimakhalira.

Zifukwa za Hyperaldosteronism Yoyamba

Monga ndanenera kale, Primary Hyperaldosteronism ndi vuto lomwe limabwera ndi ma adrenal glands anu, zomwe zimapangitsa kuti azipanga aldosterone yambiri.

Choyambitsa kwambiri izi ndi zotupa zomwe sizili khansa zotchedwa adrenal adenomas zomwe zimapangidwa m'matenda a adrenal . Izi ndi zotupa zazing'ono, zopanda vuto lililonse, koma zimatha kuyambitsa kutulutsa kwambiri kwa aldosterone.

Kuphatikiza apo, palinso zifukwa zina zingapo zachilendo :

• Kuchuluka kwa adrenal komwe kumachitika mbali imodzi - Izi zikutanthauza kuti adrenal gland imodzi yokha mbali imodzi imatupa, imakula, ndipo imapanga mahomoni ambiri.
• Khansa ya adrenocortical yomwe imapanga aldosterone - Izi ndi zotupa za khansa. Komabe, sizimachitika kawirikawiri.
• Mtundu woyamba wa matenda a hyperaldosteronism - Uwu ndi matenda omwe amabadwa nawo kuchokera kwa makolo kupita kwa ana.

Zifukwa za Hyperaldosteronism Yachiwiri

Chifukwa chachikulu cha hyperaldosteronism yachiwiri ndi kuchepa kwa kuchuluka kwa magazi komwe kumafika ku impso zanu .

Kuti mumvetse momwe izi zimachitikira, muyenera kudziwa kuti hormone ya aldosterone ndi gawo la unyolo wovuta wa mahomoni omwe amalamulira kuthamanga kwa magazi athu. Ganizirani izi ngati unyolo wobwerezabwereza.

Dongosolo ili limatchedwa dongosolo la renin-angiotensin-aldosterone . Limagwira ntchito motere:

1. Thupi lanu likamamva kuthamanga kwa magazi kotsika kapena kuchuluka kwa sodium m'magazi mwanu, impso zanu zimatulutsa enzyme yotchedwa renin .

2. Renin iyi imasintha chinthu chotchedwa angiotensinogen (choyambitsa angiotensin) chomwe chimapangidwa ndi chiwindi chanu kukhala angiotensin I. (Angiotensin ndi mahomoni omwe amatseka mitsempha yathu yamagazi.)

3. Kenako, angiotensin I iyi imakhala angiotensin II .

4. Pomaliza, angiotensin II iyi ndi yomwe imafinya mitsempha yamagazi kwambiri ndikulimbikitsa ma adrenal glands kuti atulutse hormone ya aldosterone .

Tangoganizani, ngati pazifukwa zina magazi opita ku impso achepa, impso zimaganiza kuti, 'O, kuthamanga kwa magazi kwachepa.' Kenako molakwika zimayambitsa dongosolo la renin-angiotensin-aldosterone. Zotsatira zake n'zakuti kuchuluka kwa aldosterone m'thupi kumawonjezeka, ngakhale kuti sikofunikira kwenikweni.

Zomwe zimayambitsa matenda a impso ndi hyperaldosteronism yachiwiriNazi zina mwa izi:

• Matenda a mitsempha ya impso yotsekeka - monga momwe chitoliro cha madzi chimatsekekera.
• Kuthamanga kwa magazi kwa impso
• Zinthu zomwe madzi amasonkhana m'thupi (edema) , mwachitsanzo:
• Kulephera kwa mtima
• Matenda a chiwindi (cirrhosis)
• Matenda a Nephrotic ndi matenda a impso.

Kodi mumazindikira bwanji izi?

Dokotala nthawi zambiri amazindikira hyperaldosteronism kudzera mu kuyezetsa magazi . Komabe, anthu ambiri sapezeka ndi vutoli chifukwa pali zifukwa zina zambiri komanso zoopsa zomwe zimayambitsa kuthamanga kwa magazi.

Zizindikiro zina zomwe zimadziwika kuti muli ndi hyperaldosteronism ndi izi:

• Kuthamanga kwa magazi kopanda mankhwala.
• Nazi zotsatira kuchokera ku lipoti lanu la mayeso a magazi a electrolyte :
• Kuchuluka pang'ono kwa sodium (hypernatremia) .
• Kuchepa pang'ono kwa magnesium (hypomagnesemia) .
• Komanso, kusowa kwa potaziyamu m'thupi (hypokalemia) .

Ngati dokotala wanu akuganiza kuti mwina muli ndi hyperaldosteronism kutengera zizindikiro izi, mwina ayitanitsa mayeso awiri apadera a magazi: Kuchuluka kwa Plasma Renin (PRC) kapena Plasma Renin Activity (PRA) .

• Ngati muli ndi vuto la Primary Hyperaldosteronism , kuchuluka kwa PRC ndi PRA kwanu kudzakhala kotsika kuposa masiku onse.
• Ngati muli ndi hyperaldosteronism yachiwiri , milingo iyi idzakhala yokwera kuposa yachibadwa.

Kuphatikiza apo, mungafunikenso kuyesedwa kwa aldosterone . Kuyesedwa kumeneku kumaphatikizapo kukupatsani kuchuluka kwa sodium (mchere) pakamwa kapena kudzera mu jakisoni wa saline (IV) kwa nthawi ndithu. Kenako, zitsanzo za mkodzo wanu zimasonkhanitsidwa kwa maola 24 ndipo kuchuluka kwa aldosterone mu mkodzowo kumayesedwa mu labotale.

Ngati mayesowa atsimikizira kuti muli ndi hyperaldosteronism, dokotala wanu angakupatseni mayeso ena kuti apeze chomwe chikuyambitsa. Mwachitsanzo, CT scan (computed tomography scan) kuti aone ngati chotupa chosakhala khansa chikuyambitsa hyperaldosteronism.Mungapemphedwe kuti muyese kujambula zithunzi .

Kodi mankhwala ochizira izi ndi otani?

Chithandizo cha hyperaldosteronism chimadalira chomwe chimayambitsa, koma cholinga chachikulu ndikuchepetsa kuthamanga kwa magazi .

• Pa vuto lalikulu la hyperaldosteronism, lomwe limayamba chifukwa cha chotupa cha adrenal gland, madokotala nthawi zambiri amalimbikitsa kuti chotupacho chichotsedwe ndi opaleshoni . Komabe, nthawi zina, chotupachi chingachiritsidwe ndi mankhwala okha. Ngakhale mutachita opaleshoni, mungakhalebe ndi kuthamanga kwa magazi, kotero mungafunike kumwa mankhwala kuti muchepetse vutoli.

• Kuchuluka kwa aldosteronism yachiwiri kumachiritsidwa pochepetsa kuthamanga kwa magazi ndi mankhwala, komanso pochiza chomwe chimayambitsa (monga matenda a mtima) .

Pali mitundu ingapo ya mankhwala omwe angathandize ndi hyperaldosteronism:

• Spironolactone (Spironolactone - Aldactone®)
• Eplerenone (Eplerenone - Inspra®)
• Amiloride (Amiloride - Midamor®)

Chinthu chimodzi choyenera kukumbukira ndichakuti kugwiritsa ntchito mankhwala oletsa aldosterone kwa nthawi yayitali, monga Spironolactone , kungayambitse zotsatira zina mwa amuna. Mwachitsanzo, kulephera kugwira ntchito bwino kwa erectile ndi gynecomastia zimatha kuchitika. Chifukwa chake, ndikofunikira kulankhula ndi dokotala wanu za mankhwala omwe ali abwino kwa inu, nthawi yomwe muyenera kumwa, komanso zotsatira zake.

Kodi izi zingapewedwe?

Ndipotu, nthawi zambiri, palibe chomwe mungachite kuti mupewe vutoli la hyperaldosteronism. Chifukwa limayambitsidwa ndi kusintha kwa machitidwe amkati mwa thupi lathu. Komabe, mutha kukhala ndi thanzi lanu lonse mwa kutsatira moyo wathanzi, kudya zakudya zoyenera, komanso kuchita masewera olimbitsa thupi.

Kodi chiyembekezo cha matendawa ndi chiyani?

Kuyezetsa kwa hyperaldosteronism kumadalira chifukwa chake.

• Matenda a hyperaldosteronism oyamba , ngati atapezeka msanga ndikuchiritsidwa bwino, nthawi zambiri amakhala ndi zotsatira zabwino . Ngati chotupa chachotsedwa, vutoli nthawi zambiri limawongoleredwa.
• Hyperaldosteronism yachiwiriTsogolo la matendawa limadalira momwe matenda omwe ali m'thupi (monga matenda a mtima, matenda a chiwindi) angalamuliridwe.

Mavuto akuluakulu omwe angachitike chifukwa cha hyperaldosteronism ndi mavuto a mtima ndi mitsempha yamagazi omwe amayamba chifukwa cha kuthamanga kwa magazi. Izi zikuphatikizapo:

• Kugunda kwa mtima kosakhazikika - kugunda kwa mtima kosakhazikika.
• Kuchuluka kwa magazi m'mitsempha ya kumanzere - kukhuthala kwa makoma a chipinda chakumanzere cha mtima.
• Matenda amtima
• Stroke

Ndicho chifukwa chake ndikofunikira kwambiri kuzindikira vutoli mwachangu ndikulandira chithandizo choyenera.

Kodi ndiyenera kupita kwa dokotala liti?

Ngati mwapezeka ndi matenda a hyperaldosteronism, muyenera kupita kwa dokotala nthawi zonse kuti muwonetsetse kuti mankhwala omwe mwapatsidwa akugwira ntchito bwino . Ndikofunikiranso kutsatira malangizo a dokotala wanu.

Ngati mukupeza zizindikiro zatsopano, kapena mukuwona kusintha kwa zizindikiro zomwe zilipo , dziwitsani dokotala wanu nthawi yomweyo.

Chofunika kwambiri ndichakuti, ngati muli ndi kuthamanga kwa magazi komwe sikungalandire mankhwala, lankhulani ndi dokotala wanu za nkhawa zanu, monga, "Kodi ndingakhale ndi hyperaldosteronism?" Iye akhoza kuwunika momwe mulili ndikupangira mayeso aliwonse ofunikira.

Kumbukirani kuti pali zifukwa zambiri zomwe zimayambitsa kuthamanga kwa magazi. Hyperaldosteronism ndi chimodzi mwa izo. Nkhani yabwino ndi yakuti iyi ndi matenda ochiritsika.

Uthenga Wopita Nawo Kunyumba

Chabwino, ndikukhulupirira kuti tsopano mwamvetsetsa bwino zomwe takhala tikulankhula, Hyperaldosteronism. Nazi zinthu zina zomwe muyenera kukumbukira:

• Hyperaldosteronism ndi kuchuluka kwa mahomoni a aldosterone omwe amapangidwa ndi ma adrenal glands.
• Izi zingayambitse kuthamanga kwa magazi (kuthamanga kwa magazi) komanso kuchepa kwa potaziyamu m'magazi (hypokalemia) .
• Pali mitundu iwiri ikuluikulu: Yoyamba ( vuto la ma adrenal glands okha) ndi Yachiwiri (kusonkhezeredwa kwa ma adrenal glands chifukwa cha vuto lina).
• Ngati muli ndi kuthamanga kwa magazi komwe sikulamuliridwa ndi mankhwala , muyenera kukayikira izi.
• Izi zimazindikirika kudzera mu mayeso a magazi .
• Chithandizo chimaphatikizapo kuwongolera kuthamanga kwa magazi ndi kuchiza chomwe chimayambitsa vutoli .
• Ngati zapezeka ndi kuchiritsidwa msanga, zotsatira zabwino zitha kupezeka .

Ngati muli ndi mafunso ena okhudza izi, musazengereze kufunsa dokotala wanu. Khalani ndi thanzi labwino!

Hyperaldosteronism , Hyperaldosteronism, Aldosterone, Kuthamanga kwa magazi, kuthamanga kwa magazi, Potassium, Adrenal glands, Conn's syndrome