Kodi mwazindikira posachedwapa kuti munthu wokalamba m'banja mwanu, mwina amayi anu, abambo anu, agogo anu kapena azakhali anu, akuiwala zinthu zazing'ono? Zinthu monga komwe kuli makiyi anu, dzina la munthu, ntchito yomwe mumayenera kuchita... Ndizachilendo kuti kuiwala kotereku kuchitike tikamakalamba. Koma ngati vutoli likuipiraipira pang'onopang'ono ndipo kukumbukira kwanu kufooka kwambiri moti simungathe kuchita ntchito za tsiku ndi tsiku, kungakhale chizindikiro choyambirira cha matenda ngati Alzheimer's. Ndiye zingakhale bwanji zothandiza ngati pangakhale njira yodziwira izi msanga, mosavuta? Ndicho chimene tikukamba m'nkhaniyi lero, ndipo chimatipatsa chiyembekezo chachikulu.
Kodi mayeso atsopano a magazi awa ndi otani?
Kafukufuku waposachedwapa wapeza kuti mayeso atsopano a magazi amatha kuzindikira zizindikiro za matenda a Alzheimer's. Chodabwitsa pa izi ndichakuti mayeso osavuta a magazi awa ndi olondola monga momwe mayeso omwe akugwiritsidwa ntchito pano, opweteka komanso ovuta, a msana.
Mwachidule, kuyezetsa magazi kumeneku kumayesa kuchuluka kwa puloteni inayake m'magazi mwathu yotchedwa p-tau217 . Ofufuza apeza kuti ngati munthu ali ndi kuchuluka kwakukulu kwa puloteni iyi ya p-tau217 m'magazi mwawo, ndi chizindikiro champhamvu cha kusintha kwa mapuloteni ena awiri omwe amagwirizana mwachindunji ndi matenda a Alzheimer: amyloid beta ndi tau . Awa ndi mapuloteni akuluakulu omwe amasonkhana muubongo matenda a Alzheimer akayamba.
Kuyezetsa magazi kwatsopano kumeneku kwasonyeza kulondola kwa mpaka 97% , zomwe ndi zodalirika kwambiri. Komanso, 20% yokha ya anthu omwe adachita nawo kafukufukuyu amafunikira mayeso ena kuti atsimikizire matendawa.
Kodi izi zikusiyana bwanji ndi mayeso omwe akugwiritsidwa ntchito pano?
Njira zabwino kwambiri zodziwira matenda a Alzheimer's molondola ndi zovuta pang'ono. Tiyeni tiwone zomwe zili komanso momwe zimasiyanirana ndi mayeso atsopano a magazi awa.
| Njira yoyesera | Kufotokozera | Zoyipa ndi zovuta |
|---|---|---|
| Kupopera kwa Msana | Kuyika singano yapadera kudzera mu msana ndikuchotsa madzi ochepa a msana, madzi omwe amazungulira ubongo ndi msana. | Zingakhale zopweteka, pali chiopsezo china, ndipo kugonekedwa m'chipatala n'kofunika, ndipo anthu ambiri amaopa izi. |
| Kujambula kwa PET | Chojambulira chapadera komanso chosavuta kumva chimatenga zithunzi za mapuloteni a amyloid ndi tau omwe ali muubongo. | Ndi okwera mtengo kwambiri. Malo amenewa sapezeka m'zipatala zonse. N'zovuta kwa iwo okhala kutali kuwapeza. |
| Kuyezetsa magazi kwatsopano kwa p-tau217 | Kuyesa kuchuluka kwa puloteni ya p-tau217 kudzera mu magazi otengedwa kuchokera m'mitsempha yomwe ili m'dzanja. | Ndi yosavuta kwambiri, yotsika mtengo, yotsika mtengo kwambiri poyerekeza ndi njira zina, ndipo ingathe kuchitika mosavuta kulikonse. |
Akuti mayeso a magazi omwe agwiritsidwa ntchito mu kafukufukuyu angapezeke m'maiko akunja pamtengo wapakati pa $200 ndi $500. Ngakhale kuti iyi ndi ndalama zambiri ku Sri Lanka, mtengo wake ndi wotsika kwambiri poyerekeza ndi mayeso monga PET scan, omwe amawononga madola masauzande ambiri.
Kodi ndi uthenga wotani womwe timapeza kuchokera mu kafukufukuyu?
Kafukufukuyu, wofalitsidwa mu magazini yotchuka ya zamankhwala ya JAMA Neurology, akusonyeza kuti mayeso a magazi a p-tau217 angagwiritsidwe ntchito ngati chida choyamba chowunikira mavuto okumbukira .
Taganizirani izi motere. Munthu akamaganiza kuti ali ndi vuto la kukumbukira, angayambe ndi mayeso osavuta a magazi. Pokhapokha ngati akusonyeza kuti ali ndi zizindikiro, angapitirize mayeso okwera mtengo komanso ovuta. Izi zingapulumutse odwala ndi madokotala nthawi ndi ndalama zambiri.
Chofunika kwambiri n’chakuti ngati matendawa apezeka msanga mwanjira imeneyi, mankhwala atsopano omwe amakhudza puloteni ya amyloid muubongo akhoza kuyambika msanga. Chithandizo chikayamba msanga cha matenda aliwonse, zotsatira zake zimakhala zabwino kwambiri.
Kuiwala konse ndi matenda a Alzheimer's
Matenda a Alzheimer ndi mtundu wofala kwambiri wa matenda a dementia, kapena kuchepa kwa chidziwitso. Ndizachibadwa kukhala ndi kusintha pang'ono kwa kukumbukira ndi kuganiza tikamakalamba. Komabe, ngati kusinthaku kukukhala kwakukulu kwambiri moti kungapangitse kuti zikhale zovuta kuchita ntchito za tsiku ndi tsiku, kungakhale chizindikiro cha matenda a dementia.
Mwachitsanzo, ndi chinthu chimodzi kuiwala komwe mumayika makiyi anu kenako n’kuwakumbukiranso pakapita kanthawi. Komabe, ngati mwayiwala kotheratu kuti kiyi ndi chiyani komanso kuti imagwiritsidwa ntchito chiyani, ndi vuto lalikulu. Pamenepo ndiye tiyenera kufunsa upangiri kwa dokotala.
Ndiye kodi tingayese magazi awa pompano?
Funso lofunika kwambiri ndi ili. Ngakhale kuti mayesowa akupezeka kale m'maiko ena, akadali koyambirira. Ofufuzawo akuti kafukufuku wowonjezereka akufunika kuti atsimikizire momwe zotsatirazi zimagwirira ntchito kwa anthu onse, kutanthauza anthu omwe alibe zizindikiro zilizonse.
Kuyesa kumeneku sikunachitike kawirikawiri ku Sri Lanka. Koma kwabweretsa chiyembekezo chachikulu m'magawo azachipatala padziko lonse lapansi. M'tsogolomu, tsiku lidzafika pamene ifenso tidzatha kuchita mayeso osavuta komanso otsika mtengo ngati amenewa.
Chofunika kwambiri ndichakuti, ngati inu kapena wina m'banja mwanu muli ndi kukayikira kapena mavuto okhudzana ndi kukumbukira, musapange zisankho zanu kutengera zomwe mwawerenga pa intaneti. Onetsetsani kuti mwaonana ndi dokotala wa banja lanu (dokotala) ndikukambirana za izi. Iye adzakupatsani malangizo olondola pa mayeso omwe mukufuna komanso njira zomwe muyenera kuchita, kutengera zizindikiro zanu.
Uthenga Wopita Nawo Kunyumba
- Kafukufuku wopambana akuchitika pa mayeso atsopano komanso osavuta a magazi omwe angakhale ndi chiyembekezo chodziwira matenda a Alzheimer's msanga.
- Kuyeza kumeneku kumayesa puloteni yotchedwa p-tau217 m'magazi, ndipo kwapezeka kuti ndi kolondola monga momwe mayeso okwera mtengo komanso ovuta omwe akugwiritsidwa ntchito pano.
- Izi zitha kukhala zofunika kwambiri mtsogolomu ngati njira yowunikira matendawa kuti adziwe msanga.
- Ngati inu kapena munthu amene muli naye pafupi ali ndi vuto lalikulu la kukumbukira zinthu, chinthu chabwino komanso chokhacho choti muchite ndikupempha upangiri kwa dokotala wodziwa bwino ntchito nthawi yomweyo.
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