Kodi n’zomvetsa chisoni bwanji kuona amayi anu, abambo anu, kapena munthu wina wapafupi nanu akuiwala pang’onopang’ono chilichonse? Matenda a Alzheimer, omwe amayamba ndi kuiwala mayina ndi malo, komanso kusakumbukira ngakhale zinthu zazing’ono, amakula pang’onopang’ono pakapita nthawi. Pakadali pano palibe mankhwala a matendawa. Komabe, tsopano pali mankhwala atsopano otchedwa Leqembi (lecanemab) omwe angachedwetse kufalikira kwa matendawa pachiyambi. Tiyeni tikambirane za izi mosavuta komanso mokoma mtima lero.
Kodi mankhwala otchedwa Leqembi amenewa amachita chiyani ku ubongo?
Mwachidule, Leqembi amathandiza anthu omwe ali kumayambiriro kwa matenda a Alzheimer kuti azichita zinthu zawozawo ndikukhala paokha kwa nthawi yayitali.
Taganizirani maselo a mitsempha muubongo mwathu ngati misewu ya mzinda. Chidziwitso ndi zokumbukira zimayenda m'misewu iyi. Mu matenda a Alzheimer's, mtundu wa puloteni wotchedwa 'amyloid beta' umasonkhana ndipo umasungidwa ngati milu ya zinyalala m'misewu iyi. Timatcha izi kuti 'amyloid beta plaques.' Mulu uwu wa zinyalala umalepheretsa kuyenda kwa chidziwitso pakati pa maselo a mitsempha. Ndicho chifukwa chake zinthu monga kutayika kukumbukira, kulephera kuganiza, ndi chisokonezo zimachitika pang'onopang'ono.
Mankhwala a Leqembi amachita izi mwa kuyeretsa ubongo pochotsa "ma plaque a amyloid beta ." Izi zimachepetsa kusokonezeka kwa kulumikizana pakati pa maselo a ubongo, zomwe zimachedwetsa kupita patsogolo kwa matendawa.
Chofunika kwambiri ndichakuti mankhwalawa sangabwezeretse kukumbukira komwe kwatayika. Komabe, amatha kuchepetsa kupitirira kwa matendawa ndikulola wodwalayo kukhala ndi moyo wabwino kwa nthawi yayitali.
Kodi mungapeze bwanji chithandizochi?
Iyi si piritsi yomwe mungamwe kunyumba. Leqembi ndi mankhwala amadzimadzi omwe amaperekedwa mumtsempha (kulowetsedwa m'mitsempha - kudzera mu IV) . Mankhwalawa amaperekedwa kuchipatala kapena kuchipatala, moyang'aniridwa ndi dokotala.
- Ndondomeko ya chithandizo: Mankhwalawa nthawi zambiri amaperekedwa milungu iwiri iliyonse.
- Nthawi: Gawo lililonse limatenga pafupifupi ola limodzi. Komabe, nthawi yonse yokumana ndi dokotala ingatenge nthawi yayitali chifukwa mudzayang'aniridwa musanapereke mankhwala komanso mutalandira.
- Mayeso: Musanayambe chithandizochi, dokotala wanu adzajambula MRI (Magnetic Resonance Imaging) kuti aone ngati pali ma amyloid beta plaques mu ubongo wanu. Pa nthawi ya chithandizo, MRI scan imachitidwanso kuti aone ngati mankhwalawo akugwira ntchito komanso ngati akukhudza ubongo wanu.
Ndikofunikira kwambiri kupezeka pamisonkhano ya chithandizo monga momwe dokotala wanu wakonzera. Kusiya kuigwiritsa ntchito kungachepetse mphamvu ya mankhwala.
Kodi mankhwala awa ndi abwino kwa ndani? Kodi ndi abwino kwa ndani?
Leqembi si mankhwala omwe angaperekedwe kwa odwala onse a Alzheimer's. Amaperekedwa makamaka kwa omwe ali kumayambiriro kwa matendawa. Tiyeni tifotokoze izi mozama mu tebulo ili m'munsimu.
| Udindo | Kufotokozera |
|---|---|
| Omwe ali oyenera kugwiritsa ntchito mankhwalawa |
|
| Omwe sali oyenera kugwiritsa ntchito mankhwalawa |
Zinthu zoopsa za majini
Anthu ena akhoza kukhala ndi vuto la majini lotchedwa `homozygous apolipoprotein E gene`. Anthu omwe ali ndi jini iyi ali pachiwopsezo chachikulu chotenga ARIA (yomwe yafotokozedwa pansipa), zotsatira zoyipa kwambiri za mankhwalawa. Chifukwa chake, dokotala wanu angasankhe kuchita mayeso a majini asanayambe kulandira chithandizo, ngati pakufunika kutero.
Kodi tiyeneranso kudziwa zotsatira zake?
Monga mankhwala ena aliwonse, Leqembi ikhoza kukhala ndi zotsatirapo zina. Ngakhale zina mwa izi ndi zazing'ono, pali zina zomwe tiyenera kuzidziwa bwino.
| Zotsatira zoyipa | Kufotokozera ndi zomwe muyenera kulabadira |
|---|---|
| Zochita zokhudzana ndi kulowetsedwa | Zitha kuchitika ngati mankhwala aperekedwa kudzera m'mitsempha kapena atangolandira mankhwalawa. Zizindikiro monga malungo, kuzizira, kupweteka kwa thupi, kusintha kwa kugunda kwa mtima, komanso kupuma movutikira zingachitike. Gulu lachipatala limayang'anira izi nthawi zonse. |
| ARIA (Zovuta Zokhudzana ndi Kujambula Zokhudzana ndi Amyloid) | Ichi ndi zotsatira zoyipa zomwe muyenera kusamala nazo kwambiri . Izi zingayambitse kutupa pang'ono kapena kutuluka magazi pang'ono muubongo. Anthu ambiri ali ndi ARIA popanda zizindikiro zilizonse ndipo zimatha zokha. Koma nthawi zina zimatha kukhala zoopsa. Ngati mukukumana ndi zizindikiro monga kusokonezeka mwadzidzidzi, chizungulire, kapena mutu waukulu , muyenera kudziwitsa dokotala wanu nthawi yomweyo. Madokotala nthawi zonse amafufuza vutoli pogwiritsa ntchito MRI scans. |
| Zotsatira zina zofala | Mutu ndi wofala kwambiri. Lankhulani ndi dokotala wanu za zizindikiro zilizonse zomwe zikukuvutitsani. |
Kodi ingagwirizane ndi mankhwala ena?
Inde, limenelo ndi funso lofunika kwambiri.
Ngati mukumwa mankhwala ochepetsa magazi, monga aspirin, warfarin, kapena apixaban (Eliquis) , muyenera kuuza dokotala wanu za izi. Kumwa mankhwala awa ndi Leqembi kungapangitse kuti magazi azituluka muubongo (chifukwa cha ARIA).
Kuphatikiza apo, onetsetsani kuti mwauza dokotala wanu za mankhwala ena aliwonse, mavitamini, mankhwala azitsamba, ndi zowonjezera zomwe mukumwa kuti athe kudziwa ngati mankhwalawa ndi otetezeka kwa inu.
Uthenga Wopita Nawo Kunyumba
- Leqembi si mankhwala a matenda a Alzheimer's. Ndi mankhwala omwe amachepetsa liwiro la matendawa.
- Mankhwalawa ndi abwino kwambiri kwa omwe ali kumayambiriro kwa matendawa, omwe ali ndi zizindikiro zochepa.
- Mankhwalawa amagwira ntchito pochotsa ma `amyloid beta plaques` omwe amasonkhana muubongo.
- Pa nthawi ya chithandizo, dokotala nthawi zonse amachita MRI scan kuti aone ngati pali zotsatirapo zoyipa monga ARIA.
- Ndikofunikira kudziwitsa dokotala wanu za mankhwala ena onse omwe mukumwa, makamaka mankhwala ochepetsa magazi.
- Ndikofunikira kwambiri kupanga chisankho mutakambirana mosamala ndi dokotala wanu ngati chithandizochi chili choyenera kwa inu komanso ubwino ndi kuipa kwake.
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