Kodi mumavutikanso kupuma chifukwa cha mphumu kapena ziwengo? Ndiye tiyeni tiphunzire za Leukotriene Modifiers izi!

Nthawi zina, ngakhale fumbi laling'ono, mungu, kapena chakudya zingakupangitseni kumva kuti mulibe mpweya wokwanira, chifuwa chanu chimalimba, kapena chifuwa chosalekeza. Mwina muli ndi mphuno yotuluka madzi , kuyetsemula, kapena pakhosi pokanda. Izi zimakwiyitsa kwambiri, sichoncho? Nthawi zambiri, zizindikirozi zimayambitsidwa ndi zomwe zimachitika m'thupi lathu. Lero, tikambirana za mtundu wapadera wa mankhwala omwe angathandize kuchepetsa mavuto opuma omwe amayamba chifukwa cha matenda monga mphumu ndi ziwengo. Amatchedwa Leukotriene Modifiers .

Kodi ma leukotrienes ndi chiyani? N’chifukwa chiyani amativutitsa?

Mwachidule, ma leukotriene ndi mankhwala omwe matupi athu amapanga. Sikuti amangopangidwa mwangozi. Tangoganizirani, mukakhala ndi vuto la chinthu china, kutanthauza kuti, chinthu china chikalowa m'thupi mwanu, mwachitsanzo fumbi, mungu, zakudya zina, ndiye kuti chitetezo chathu cha mthupi chimayamba kugwira ntchito mwadzidzidzi ndikutulutsa ma leukotriene amenewa.

Tikatulutsa ma leukotriene amenewa, timayamba kukhala ndi mavuto. Makamaka dongosolo la kupuma limakhudzidwa kwambiri. Tiyeni tiwone zomwe zimachitika:

• Chifuwa: Chifuwa chosatha, nthawi zina chopweteka chingakhalepo.
• Kuchuluka kwa mamina: Madzi monga mamina ndi mafinya amayamba kusonkhana pachifuwa ndi pakhosi. Izi zingayambitse phokoso la mluzu pamene mukupuma.
• Kutupa kwa njira zopumira: Njira zathu zopumira, malo omwe timapumira, zimayamba kutupa kuchokera mkati. Monga momwe chitoliro cha madzi chimafufumira kuchokera mkati, malo oti madzi adutsemo amakhala ochepa.
• Kupindika kwa minofu ya mpweya: Minofu yaying'ono yozungulira njira zopumira mpweya imalimba ndikufinya, zomwe zimapangitsa njira zopumira mpweya kukhala zochepa kwambiri.
• Kulimba kwa chifuwa: Zingamveke ngati wina akukufinya pachifuwa, ngati akukufinya.
• Kuvuta kupuma kapena kupuma movutikira: Zonsezi zikaphatikizidwa, kupuma kumakhala kovuta kwambiri. Anthu ena amatha kupuma movutikira.

Mukuona, mankhwala ang'onoang'ono awa otchedwa leukotrienes akutibweretsera mavuto ambiri.

Kodi mankhwala osinthira a leukotriene awa ndi chiyani? Kodi mankhwala awa amathandiza bwanji?

Chabwino, tsopano tikudziwa kuti ma leukotriene nthawi zambiri ndi omwe amachititsa mavuto opuma awa. Ma leukotriene modifiers ndi mtundu wa mankhwala omwe amawongolera ndikusintha momwe ma leukotrienes amagwirira ntchito. Amatchedwanso kuti leukotriene receptor antagonists kapena leukotriene synthesis inhibitors.Chabwino. Ngakhale kuti dzinali ndi lovuta pang'ono, mankhwala awa amachita chinthu chofunikira kwambiri.

Mankhwalawa amagwiritsidwa ntchito makamaka pa:

• Matenda a ziwengo, makamaka matenda a ziwengo: Izi ndi zomwe nthawi zambiri timazitcha kuti ziwengo kwa nthata za fumbi kapena amphaka. Zizindikiro zake ndi monga mphuno yotuluka madzi, kuyetsemula, kutsekeka kwa mphuno, ndi maso oyabwa.
• Mphumu Yosapatsa Thanzi: Ngati zizindikiro za mphumu zikukulirakulira chifukwa cha chifuwa, mankhwalawa angathandize.
• Mphumu yoyambitsidwa ndi kuchita masewera olimbitsa thupi: Anthu ena amatha kuwona kuwonjezeka kwa zizindikiro zawo za mphumu akamachita masewera olimbitsa thupi, kuthamanga, kapena kulumpha. Mankhwalawa ndi othandizanso pazochitika zotere.

Chofunika kwambiri ndichakuti mankhwalawa asagwiritsidwe ntchito kuchepetsa msanga vuto la ziwengo kapena mphumu lomwe layamba kale. Amagwiritsidwa ntchito kupewa mavuto otere kapena kuchepetsa zizindikiro zake . Zili ngati ambulera, ngati muyikweza mvula isanagwe, simudzanyowa. Umu ndi momwe zilili.

Kodi pali mitundu iti ya Leukotriene Modifiers?

Pali mitundu ingapo ya mankhwala m'gululi. Dokotala wanu akakupatsani imodzi, ingatchedwe imodzi mwa mayina awa:

• Montelukast - Mwina munamvapo izi pansi pa dzina la `Singulair®`.
• Zafirlukast - Izi zimabwera pansi pa dzina la kampani ya `Accolate®`.
• Zileuton - Izi zikupezeka pansi pa dzina la kampani ya `Zyflo®`.

Zonsezi zitatu zimagwiritsidwa ntchito pochiza mphumu. Komabe, Montelukast yokha ndi yomwe yavomerezedwa kuchiza matenda a chifuwa chachikulu (allergies rhinitis) , kutanthauza kuti, matenda a m'mphuno.

Kodi mankhwala awa amagwira ntchito bwanji? Ndi zodabwitsa, sichoncho?

Mankhwalawa amagwira ntchito m'njira ziwiri. Zili ngati pali njira ziwiri zothetsera vuto.

1. Montelukast ndi Zafirlukast zili m'gulu la mankhwala otchedwa leukotriene receptor antagonists . Tangoganizani kuti pali 'maloko' ang'onoang'ono m'thupi lanu, ndipo pamene mankhwala otchedwa leukotriene abwera n'kulowa mu loko ngati 'kiyi', vuto la kupuma limakhalapo. Chomwe mankhwalawa amachita ndichakuti, kiyi iyi ya leukotriene isanalowe mu loko, imatseka lokoyo poika kiyi ina 'yopanda pake'. Kenako ma leukotriene amenewo sagwira ntchito. Ndiye kuti, amaletsa mphamvu ya ma leukotriene.

2. Zileuton ndi yosiyana pang'ono. Ili m'gulu la mankhwala otchedwa leukotriene synthesis inhibitors.Izi ndi zomwe imachita popanga mankhwala 'ovuta' otchedwa leukotrienes mkati mwa thupi, kutanthauza kuchepetsa kupanga kwawo. Zili ngati kuyimitsa kupanga katundu mu fakitale. Kenako kuchuluka kwa ma leukotrienes m'thupi kumachepa.

Kodi mukumvetsa? Mwanjira ina, sizimalola kuti ma leukotriene agwire ntchito, ndipo mwanjira ina, zimachepetsa kupanga ma leukotriene.

Kodi ndingagwiritse ntchito bwanji mankhwalawa? Ndiyenera kusamala ndi chiyani?

Mankhwala osinthira a leukotriene nthawi zambiri amabwera ngati mapiritsi, zomwe zikutanthauza kuti amamwedwa pakamwa .

Chofunika kwambiri ndikumwa mankhwalawa tsiku lililonse monga momwe dokotala wanu wanenera . Ndikofunikira kumwa mankhwalawa pa nthawi yake, kaya mukuvutika kupuma tsiku limenelo kapena ayi. Chifukwa, monga tanenera kale, awa amagwiritsidwa ntchito popewa mavuto opuma. Monga vitamini ya tsiku ndi tsiku, muyenera kumwa tsiku lililonse kuti mukhale ndi chitetezo chomwe chimapereka.

Dokotala wanu adzakupatsani malangizo ena okhudza mankhwalawa:

• Mlingo: Izi zikutanthauza kuchuluka kwa mankhwala omwe ayenera kumwedwa komanso kangati patsiku.
• Nthawi yoti mumwere mankhwala: M'mawa, kawiri patsiku, kapena usiku. Izi zitha kutengera nthawi yomwe zizindikiro zanu zili zowopsa kwambiri.
• Kaya mutenge ndi chakudya kapena ayi: Mankhwala ena ayenera kumwedwa musanadye, ena mutadya. Pemphani mosamala.

Musamwe mankhwala ochulukirapo kapena ochepa kuposa omwe dokotala wanu wakupatsani. Kuchita zimenezi kungachepetse mphamvu ya mankhwalawo ndikuyambitsa zotsatirapo zosafunikira.

Kodi ubwino wogwiritsa ntchito Leukotriene Modifiers ndi wotani?

Ngati mugwiritsa ntchito mankhwala awa moyenera, mutha kupeza mpumulo wambiri. Nazi ubwino wake:

• Kupuma kumakhala kosavuta: Kulimba pachifuwa ndi kupuma pang'onopang'ono kumachepa, ndipo mutha kupuma momasuka.
• Mungathe kuchita masewera olimbitsa thupi ngakhale mutavutika kupuma: Ngati munakhalapo ndi vuto la kupuma movutikira mukuchita masewera olimbitsa thupi, mankhwalawa adzakuthandizani kuwongolera vutoli ndikuchita masewera olimbitsa thupi.
• Zimathandiza kuti njira zopumira mpweya zikhale zotseguka: Tinanena kuti njira zopumira mpweya zimatupa ndipo zimakhala zolimba, motero zimachepetsa mavuto amenewo.
• Amachepetsa mamina pachifuwa ndi pakhosi: Mamina amachepa, zomwe zimapangitsa kuti kupuma kukhale kosavuta.
• Zimathandiza kupewa mavuto opuma, monga matenda a ziwengo ndi matenda a mphumu.
• Amachepetsa kuchuluka ndi kuopsa kwa zochita ndi kuukira.

Izi zingathandize kuti moyo wanu watsiku ndi tsiku ukhale wosavuta.

Kodi pali zoopsa zilizonse ndi mankhwalawa?

Monga mankhwala ena aliwonse, mankhwala osinthira a leukotriene awa akhoza kukhala ndi zoopsa zina.

Kuwonongeka kwa chiwindi komwe kumachitika chifukwa cha mankhwala ena osinthira leukotrieneN'zotheka. Chifukwa chake, ngati muli kale ndi vuto la chiwindi, simungathe kugwiritsa ntchito mankhwalawa. Pamene mukumwa mankhwalawa, dokotala wanu angachitenso mayeso a magazi kuti aone ngati chiwindi chanu chikugwira ntchito bwino. Izi ndi za chitetezo chanu.

Kodi zotsatirapo zake zingakhale zotani?

Mankhwala osinthira a leukotriene nthawi zambiri amaonedwa kuti ndi otetezeka. Komabe, anthu ena akhoza kukhala ndi zotsatirapo zoyipa. Musadandaule, nthawi zambiri izi sizikhala zoopsa.

Zotsatira zoyipa zomwe zimawonedwa kawirikawiri:

• Zizindikiro za chimfine: chifuwa, pakhosi lopweteka, mphuno yotuluka madzi.
• Kusokonezeka m'mimba: Kutsegula m'mimba, kupweteka m'mimba.
• Matenda a m'khutu.
• Kutopa: Kumatanthauza kumva kutopa.
• Zizindikiro zofanana ndi chimfine: malungo.
• Mutu .
• Kutentha pamtima: Kumamveka ngati kutentha pachifuwa.
• Kuyabwa kapena ziphuphu.
• Chakudyacho sichikoma.
• Kusanza: Kumva ngati ukufuna kusanza.

Ngati mukukumana ndi zotsatira zoyipa ngati izi, ngati sizitha pakatha masiku ochepa, kapena ngati zikukuvutani kupirira, lankhulani ndi dokotala wanu.

Komabe, nthawi zina zotsatirapo zoyipa kwambiri zimatha kuchitika. Ngati muwona chilichonse chonga ichi, muyenera kuwona dokotala kapena kupita kuchipatala nthawi yomweyo:

• Kusintha kwa thanzi la maganizo: Izi ndizofunikira kwambiri. Ngati mukukumana ndi kuvutika maganizo , maganizo ofuna kudzipha , kapena kukwiya mwadzidzidzi , musanyalanyaze. Anthu ena omwe akumwa mankhwalawa anena kuti akumana ndi mavuto amisala awa. Chifukwa chake, ngati inu kapena wina m'banja mwanu awona kusintha kwakukulu kwa khalidwe kapena malingaliro pamene akumwa mankhwalawa, uzani dokotala nthawi yomweyo.
• Matuza, kutsekeka, kapena ziphuphu zoopsa monga mabala.
• Kusanza kapena kupweteka pakhosi.
• Kugunda kwa mtima.
• Kumva dzanzi kapena kumva kunjenjemera m'miyendo.
• Kutupa kwa nkhope, maso, pakamwa, kapena pakhosi.
• Kuvuta kupuma kapena kumeza.
• Kusanza.
• Kuoneka kwachikasu pakhungu kapena m'maso (Jaundice): Izi zitha kukhala vuto la chiwindi.

Ngati mukuona chinthu chachikulu ngati ichi, ndi bwino kufunafuna upangiri kwa dokotala popanda kuwononga nthawi.

Kodi pali kuyanjana kulikonse ndi mankhwala ena?

Inde, Leukotriene Modifiers imatha kuyanjana ndi mankhwala ena omwe mukumwa. Chifukwa chake, ndikofunikira kwambiri kuuza dokotala wanu za mankhwala onse omwe mukumwa, kuphatikiza mankhwala olembedwa ndi dokotala, mankhwala ochepetsa ululu omwe amaperekedwa ndi dokotala, mavitamini, ndi mankhwala azitsamba.

Mankhwala ena omwe angagwirizane ndi mankhwalawa ndi awa:

• Mankhwala ena a khansa (monga `Alpelisib`, `dabrafenib`, `enzalutamide`).
• Mitundu ina ya maantibayotiki (monga `Erythromycin`, `rifapentine`).
• Mankhwala ena a matenda amisala (monga Loxapine - mankhwala a matenda ofanana ndi schizophrenia ).
• Mankhwala a cystic fibrosis (monga Lumacaftor).
• Mankhwala ena oletsa kutupa (monga Terfenadine - mankhwala ogwiritsidwa ntchito popewa kapena kuchiza zizindikiro za ziwengo).
• Mankhwala ochepetsa magazi (monga `Warfarin` - mankhwala omwe amathandiza kupewa magazi kuundana, sitiroko, ndi matenda a mtima).

Mndandandawu sunathe. Choncho, onetsetsani kuti mwakambirana ndi dokotala wanu mankhwala onse omwe mumamwa kuti akupatseni chithandizo chotetezeka komanso choyenera kwambiri.

Uthenga Wopita Nawo Kunyumba

Chabwino, ndikukhulupirira kuti tsopano mwamvetsa bwino za Leukotriene Modifiers zomwe takambirana lero.

Mwachidule, mankhwala awa amathandiza kupewa mavuto opuma omwe amayamba chifukwa cha ziwengo kapena mphumu. Ayenera kumwedwa tsiku lililonse, kaya muli ndi zizindikiro kapena ayi, komanso monga momwe dokotala wanu walangizira. Dokotala wanu ndiye munthu wabwino kwambiri wodziwa ngati mankhwalawa ndi oyenera kwa inu komanso ngati angakupindulitseni.

Choncho, ngati muli ndi mavuto otere okhudza kupuma, musaope kulankhula ndi dokotala ndikufunsa za mitundu iyi ya mankhwala. Aliyense ayenera kupuma momasuka ndikukhala ndi moyo wathanzi!

Leukotrienes , mankhwala osinthira leukotriene, mphumu, ziwengo, mavuto opuma, montelukast, zafirlukast, zileuton, matenda opuma