Kodi mwadzidzidzi mwayamba kuundana magazi, kapena munakhala ndi vuto linalake panthawi ya mimba ndipo dokotala anakuyezani magazi? Kodi munada nkhawa lipotilo litanena kuti 'Lupus Anticoagulant positive'? Kodi munachita mantha mutaona mawu oti 'lupus' ndipo munaganiza kuti ndi lupus? Dzinali kwenikweni ndi losokoneza pang'ono. Ndicho chifukwa chake anthu ambiri ali ndi kusamvetsetsana pankhaniyi. Tiyeni tithetse mavuto onse okhudza izi lero.
Kodi kwenikweni Lupus Anticoagulant ndi chiyani?
Mwachidule, uwu ndi mtundu wa antibody womwe ungakhalepo m'magazi athu.
Taganizirani za chitetezo cha mthupi lathu ngati gulu lankhondo lomwe limateteza dziko. Pamene kachilombo kapena chinthu choopsa chilowa m'thupi kuchokera kunja, gulu lankhondoli limazindikira mdaniyo ndipo limapanga gulu la asilikali apadera, otchedwa ma antibodies, kuti aliwononge. Izi ndi zomwe zimachitika nthawi zambiri.
Koma nthawi zina chitetezo chathu chamthupi chimasokonekera. M'malo moukira anthu ochokera kunja, chimayamba kuukira maselo athu athanzi . Umu ndi momwe lupus anticoagulant (LA) ilili antibody yomwe imapangidwa mwangozi ndikuwononga thupi lathu.
Antibody iyi ya LA, pamodzi ndi ma antibodies ena awiri, ingayambitse matenda otchedwa Antiphospholipid Syndrome (APS) . Uwu ndi matenda odziyimira pawokha. Chizindikiro chachikulu cha izi ndichakuti chiopsezo cha magazi kuundana m'mitsempha yamagazi ya thupi chimakhala chachikulu kwambiri kuposa munthu wamba.
Nanga n’chifukwa chiyani zimenezi zimatchedwa 'lupus'? Kodi uwu ndi matenda omwewo monga lupus?
Apa ndi pomwe anthu ambiri amasokonezeka komanso kuchita mantha. Ngakhale kuti pali gawo la 'lupus' m'dzina, lupus kwenikweni ndi zinthu ziwiri zosiyana: Lupus Anti-Coagulant (LA) ndi matenda a Lupus. Ndi nkhani yosangalatsa kwambiri momwe dzinali linayambira.
Kachilombo kameneka kanapezeka koyamba zaka makumi angapo zapitazo pamene ofufuza anayesa zitsanzo za magazi kuchokera kwa odwala lupus. Choncho anaganiza kuti ndi chinthu chapadera kwa odwala lupus.
Anaonanso kuti zitsanzo za magazi zomwe zili ndi antibody iyi zimatenga nthawi yayitali kuposa yachibadwa kuti ziume mu vitro. 'Anticoagulant' amatanthauza 'amaletsa magazi kuundana.' Choncho, adatcha 'lupus anticoagulant', kutanthauza 'chinachake m'thupi la odwala lupus chomwe chimaletsa magazi kuundana.'
Komabe, malingaliro onse awiriwa pambuyo pake adapezeka kuti ndi olakwika. Ndipotu, zosiyana ndi zimenezo ndi zoona. Chomwe antibody iyi imachita mkati mwa thupi ndikuwonjezera magazi kuundana, osati kuletsa!
Kuti muthetse chisokonezochi, onani tebulo ili m'munsimu.
| Zoona | Mankhwala oletsa magazi kuundana a Lupus (LA) | Matenda a Lupus (SLE) |
|---|---|---|
| Chilengedwe | Kachilombo koyambitsa matenda koopsa m'magazi. | Matenda ovuta a autoimmune omwe amakhudza ziwalo zosiyanasiyana m'thupi. |
| Zotsatira zazikulu | Zimawonjezera chiopsezo cha magazi kuundana. | Magawo ambiri a thupi amatha kukhudzidwa, monga khungu, mafupa, impso, mtima, ndi ubongo. |
| Ubale | Kukhala ndi LA sikutanthauza kuti uli ndi lupus, koma anthu ena omwe ali ndi lupus akhoza kukhala ndi LA. | LA ndi chimodzi mwa zinthu zomwe zingagwirizane ndi lupus. |
N’chifukwa chiyani zinthu ngati zimenezi zimachitikira matupi athu?
Izi zili choncho chifukwa chitetezo chathu chamthupi chimalakwitsa. Ma antibodies a LA awa amaukira mapuloteni omwe amalumikizidwa ku mtundu wa mafuta otchedwa phospholipids omwe ali pamwamba pa maselo athu. Kuukira kumeneku kumawononga maselo, kuwapangitsa kuti azigwirizana ndikuwonjezera chiopsezo cha magazi kuundana.
Akatswiri sakudziwabe chifukwa chake chitetezo cha mthupi chimayamba kupanga ma antibodies olakwikawa. Amakhulupirira kuti izi zitha kukhala chifukwa cha majini, zinthu zachilengedwe, kapena matenda ena opatsirana.
Kodi LA positive imatanthauza chiyani? Zidzandikhudza bwanji?
Kukhala ndi LA m'magazi anu kumatanthauza kuti muli pachiwopsezo chotenga matenda otchedwa antiphospholipid syndrome (APS). Pano, 'muli pachiwopsezo'Mawu oti "chifuniro" ndi ofunikira kwambiri. Sizitanthauza kuti zidzachitikadi.
Ngakhale kuti antibody ya LA ilipo m'magazi, pali anthu ambiri omwe amakhalabe athanzi moyo wawo wonse popanda kupangika magazi kapena zovuta zina.
Choncho musamachite mantha kwambiri mukaona izi pa lipoti lanu. Komabe, ndikofunikira kuti dokotala wanu adziwe izi ndikukuyang'anirani. Popeza muli ndi mwayi waukulu woti magazi aziundana kuposa ena, ndi bwino kudziwa zimenezo.
Kodi mankhwala ochizira izi ndi otani?
Palibe mankhwala omwe achotsa kwathunthu antibody iyi ya LA m'thupi. Koma pali mankhwala abwino kwambiri oletsa kuwonongeka komwe kungayambitse, makamaka kupanga magazi kuundana.
Ngati mulibe zizindikiro, zomwe zikutanthauza kuti simunakhalepo ndi magazi oundana kale, dokotala wanu angasankhe kungokuyang'anirani popanda kukupatsani mankhwala aliwonse.
Komabe, ngati munayamba mwakhala ndi magazi oundana kale kapena munapezeka ndi APS, chithandizo chachikulu ndi mankhwala oletsa magazi kuundana kapena ochepetsa magazi . Mankhwala monga warfarin ndi heparin amaperekedwa kuti achepetse chiopsezo cha magazi kuundana. Nthawi zina, mankhwala monga corticosteroids amaperekedwanso kuti achepetse kugwira ntchito mopitirira muyeso kwa chitetezo cha mthupi.
Mankhwala onsewa amasankhidwa ndi dokotala wanu, poganizira zinthu zambiri monga matenda anu, zaka zanu, ndi matenda ena.
Kodi ndiyenera kupita kwa dokotala liti? Kodi vuto ladzidzidzi ndi chiyani?
Mukakhala ndi vutoli, ndikofunikira kwambiri kudziwa kusiyana pakati pa zochitika zachizolowezi ndi zadzidzidzi.
| Mwayi | Zoyenera kuchita |
|---|---|
| Kuwona konse | Pitani ku chipatala panthawi yomwe mwakonza kuti mukayezedwe monga momwe dokotala wanenera. Adzayesa magazi kuti aone ngati mlingo wa mankhwalawo ndi wolondola komanso ngati pali kusintha kwina kulikonse. |
| Zadzidzidzi (pitani ku ETU nthawi yomweyo) |
|
Zizindikiro zochenjeza za magazi kuundana
- Mwendo (Deep Vein Thrombosis - DVT): Kutupa mwadzidzidzi, kufiira, kutentha, ndi kupweteka mwendo umodzi.
- Kupuma movutikira: Kupuma movutikira, kupweteka pachifuwa (makamaka popuma), kukoholera magazi.
- Kupweteka mutu: kugwada mbali imodzi ya nkhope, kutayika kwa mkono umodzi, kuvutika kulankhula.
Ngati zizindikiro zilizonsezi zikuwonekera, pitani ku chipatala cha Emergency Treatment Unit (ETU) mwamsanga .
Uthenga Wopita Nawo Kunyumba
- Lupus anticoagulant (LA) si lupus yokha. Ndi mtundu wa antibody m'magazi.
- Kukhala ndi LA m'magazi anu kumatanthauza kuti muli pachiwopsezo chachikulu chotenga magazi kuundana. Sizikutanthauza kuti zidzachitikadi.
- Musachite mantha mutaona lipotilo. Koma lankhulani ndi dokotala wanu za izi ndipo tsatirani malangizo ake.
- Cholinga chachikulu cha chithandizo ndikuletsa magazi kuundana kuti asapangike. Dokotala wanu adzakukonzerani chithandizo chabwino kwambiri.
- Nthawi zonse dziwani zizindikiro zochenjeza za magazi kuundana (kutupa m'miyendo, kupweteka pachifuwa, kuvutika kupuma). Ngati chizindikiro chotere chikuwonekera, pitani ku ETU nthawi yomweyo.
- Ndizachibadwa kukhala ndi mantha komanso nkhawa mukaganiza kuti chinthu chomwe simungachione m'thupi lanu chingakupwetekeni. M'malo mokhala ndi mantha, khalani ndi chidziwitso komanso kuganizira bwino. Dokotala wanu angakuthandizeni paulendo umenewo.
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