Kodi munamvapo dzina lakuti 'Methylene Blue'? Mwina ayi. Ndi mankhwala osowa koma ofunikira kwambiri. M'mawonekedwe ake enieni, amaoneka ngati madzi abuluu akuya. Ngakhale kuti angawoneke ngati utoto wamba wa nsalu, ali ndi mphamvu zochizira matenda angapo akuluakulu. Tiyeni tiwone bwino nkhani yomwe ili kumbuyo kwa mankhwala apadera abuluu awa.
Kodi Methylene Blue ndi chiyani kwenikweni?
Mwachidule, Methylene Blue ndi mankhwala omwe madokotala amagwiritsa ntchito pochiza matenda osowa magazi otchedwa methemoglobinemia . Ngakhale kuti ndi mankhwala olimba, amaperekedwa ngati madzi abuluu kudzera mu jakisoni mwachindunji mumtsempha wanu.
Mbiri ya mankhwala amenewa ndi yosangalatsa. Anapezeka koyamba ndi katswiri wa zamankhwala waku Germany m'zaka za m'ma 1800. Poyamba, ankagwiritsidwa ntchito ngati utoto m'makampani opanga nsalu ndipo pambuyo pake ankagwiritsidwa ntchito ngati utoto m'mayesero a labotale.
Zaka pafupifupi 125 zapitazo, dokotala wina wa ku Germany anayamba kugwiritsa ntchito mankhwalawa pochiza malungo. Kuyambira pamenepo, ntchito zake zachipatala zasintha kwambiri. Pakadali pano, zavomerezedwa ndi FDA makamaka pochiza methemoglobinemia. Komabe, madokotala nthawi zina angagwiritse ntchito mankhwalawa pa matenda ena.
Kodi mankhwalawa amagwiritsidwa ntchito pa matenda otani?
Monga tanenera, kugwiritsa ntchito kwakukulu kwa Methylene Blue ndikuchiza methemoglobinemia.
Ndiye, kodi methemoglobinemia ndi chiyani?
Imeneyi ndi matenda okhudzana ndi magazi. Mwachidule, mukakhala ndi vutoli, maselo ofiira a magazi anu sangathe kunyamula mpweya kupita ku minofu ya thupi lanu.
Thupi likasowa mpweya wokwanira, malo monga milomo yanu, khungu, lilime, ndi misomali yanu imatha kukhala yabuluu. Izi zimadziwika kuti cyanosis . Mwa makanda, nthawi zina izi zimatchedwa 'blue baby syndrome'.
Anthu ena amatengera matendawa m'majini awo. Komabe, ambiri amadwala matendawa chifukwa chogwiritsa ntchito mankhwala enaake, mankhwala osokoneza bongo, kapena kugwiritsa ntchito mankhwala enaake.
Methemoglobinemia ikhoza kukhala vuto lomwe lingawononge moyo . Methylene Blue ndi imodzi mwa njira zothandiza kwambiri zochizira matendawa.
Kodi mankhwalawa amagwira ntchito bwanji?
Methylene Blue imalowa m'magazi mwanu ndipo imakumana ndi kusintha kwa mankhwala komwe kumasintha methemoglobin (yomwe singathe kunyamula mpweya) kukhala hemoglobin yogwira ntchito (yomwe ingathe). Ganizirani izi ngati 'kubwezeretsanso' mphamvu ya magazi anu yonyamula mpweya.
Mankhwalawa amaperekedwa kuchipatala kapena ku chipatala ndi dokotala kapena namwino ngati njira yothira m'mitsempha. Nthawi zambiri njirayi imatenga mphindi 5 mpaka 30. Nthawi zambiri, mlingo umodzi ndi wokwanira kuchepetsa zizindikiro. Komabe, ngati zizindikiro zikupitirira patatha ola limodzi, dokotala wanu angasankhe kupereka mlingo wina.
Zotsatirapo zoyipa ndi kuyanjana kwa mankhwala ( zotsatira zoyipa ndi kuyanjana)
Musanapereke mankhwalawa, dokotala wanu adzayang'ananso mbiri yanu yonse yachipatala, chifukwa ikhoza kukhala yotetezeka kwa anthu omwe ali ndi matenda enaake.
| Kusowa kwa G6PD | Imeneyi ndi matenda a m'magazi omwe amabadwa nawo. Ngati munthu amene ali ndi vutoli alandira Methylene Blue, imatha kuwononga maselo ofiira a magazi mwachangu (hemolysis) , zomwe zimapangitsa kuti pakhale ngozi yaikulu yachipatala. Izi ndizofunikira kwambiri. |
| Mimba kapena kuyamwitsa | Ngati muli ndi pakati, mukukonzekera kutenga pakati, kapena mukuyamwitsa, muyenera kudziwitsa dokotala wanu. |
| Mikhalidwe ina | Chonde dziwitsani dokotala wanu ngati muli ndi mbiri ya matenda a impso kapena chiwindi. |
| Matenda a ziwengo | Uzani dokotala wanu ngati muli ndi vuto la Methylene Blue kapena mankhwala ena aliwonse, zakudya, kapena utoto. |
| Kupha poizoni wa cyanide | Ngati pali kukayikira kulikonse kwa poizoni wa cyanide, muyenera kuuza dokotala wanu nthawi yomweyo. |
Kodi zotsatira zake ndi ziti?
Monga mankhwala ena onse, Methylene Blue ingayambitse zotsatirapo zoyipa.
- Zotsatirapo zazing'ono (nthawi zambiri sizimayambitsa mantha):
- Kusintha kwa mtundu wa mkodzo ndi ndowe zabuluu-zobiriwira (izi zimachitika kawirikawiri chifukwa cha mtundu wa utoto).
- Kusanza ndi kusanza .
- Kusintha pang'ono kwa khungu.
- Ululu pamalo omwe jakisoni amaperekedwa.
- Zotsatirapo zoyipa zomwe zimafuna chithandizo chamankhwala mwachangu:
- Kupweteka pachifuwa.
- Chizungulire.
- Mutu.
- Chisokonezo.
- Kuchuluka kwa thukuta.
- Kupweteka m'mimba.
Kuyanjana kwa Mankhwala
Gawo ili ndi lofunika kwambiri. Kumwa mankhwala ena pamodzi ndi Methylene Blue kungakhale ndi zotsatira zoopsa.
Makamaka, mankhwala ena omwe amagwiritsidwa ntchito pochiza kuvutika maganizo kapena nkhawa (monga SSRIs) angayambitse matenda oopsa otchedwa 'Serotonin Syndrome' ngati ataphatikizidwa ndi Methylene Blue.
Izi zimachitika pamene kuchuluka kwa serotonin muubongo wanu kwakwera kwambiri, zomwe zimapangitsa kuti mukhale ndi zizindikiro monga kunjenjemera, kutentha thupi kwambiri, komanso kutaya chidziwitso, zomwe zingakhale zoopsa. Pachifukwa ichi, muyenera kupatsa dokotala wanu mndandanda wonse wa mankhwala onse, mavitamini, ndi zowonjezera zakudya zomwe mukumwa pakadali pano.
Ntchito zina ndi kafukufuku
Ngakhale kuti FDA yavomereza kuti igwiritsidwe ntchito pa methemoglobinemia yokha, madokotala nthawi zina amagwiritsa ntchito ngati mankhwala osakhala a gulu la mankhwala m'malo enaake azachipatala.
- Mankhwala Oletsa Kutupa: Amagwiritsidwa ntchito ngati mankhwala oletsa poizoni wa mankhwala ochokera ku zinthu monga nitrites. Ngati mukukayikira kuti mankhwala oletsa kutupa amachokera ku mankhwala, pitani ku dipatimenti yadzidzidzi yapafupi nthawi yomweyo.
- Kugwedezeka: Kumagwiritsidwa ntchito pochiza matenda oopsa a kugwedezeka m'zipinda zosamalira odwala kwambiri (ICU).
- Kuzindikira khansa:Amagwiritsidwa ntchito ngati utoto pa opaleshoni ya khansa kuti awonetse maselo a khansa ndi ma lymph nodes.
- Kafukufuku wa zamaganizo: Kafukufuku akupitilira kuti awone ngati angathandize matenda monga Alzheimer's.
- Mankhwala Ophera Tizilombo: Kafukufuku wina akusonyeza kuti Methylene Blue, ikagwiritsidwa ntchito ndi kuwala, ingathandize kuwononga majeremusi ndi mavairasi ena.
Chofunika: Mapulogalamu ambiri awa akadali mu gawo lofufuza. Musayese kugwiritsa ntchito mankhwalawa kutengera zomwe zapezeka pa intaneti. Nthawi zonse tsatirani malangizo a dokotala wanu.
Uthenga Wopita Nawo Kunyumba
- Methylene Blue ndi mankhwala apadera a matenda osowa koma oopsa a magazi, methemoglobinemia.
- Musagwiritse ntchito mankhwalawa nokha. Nthawi zonse ayenera kuperekedwa kudzera m'mitsempha motsogozedwa ndi dokotala kapena namwino kuchipatala.
- Ngati muli ndi vuto la G6PD , ndikofunikira kuti mudziwitse dokotala wanu, chifukwa izi ndizofunikira kwambiri kuti mukhale otetezeka.
- Uzani dokotala wanu za mankhwala ena onse omwe mukumwa (makamaka mankhwala oletsa kuvutika maganizo) kuti mupewe chiopsezo cha Serotonin Syndrome.
- Mkodzo wabuluu-wobiriwira ndi zotsatira zabwinobwino za mankhwala; musachite mantha. Komabe, funani thandizo lachipatala mwamsanga ngati mukumva kupweteka pachifuwa kapena kusokonezeka.
- Njira zina zomwe zingagwiritsidwe ntchito pa mankhwalawa zikupitilirabe kugwiritsidwa ntchito mwachiyembekezo. Nthawi zonse dalirani upangiri wa dokotala wanu.
Methylene Blue, Methemoglobinemia, Cyanosis, kusowa kwa G6PD, Serotonin Syndrome, Zotsatira zoyipa za mankhwala
