Kodi Methylene Blue ndi chiyani? Tiyeni tiphunzire zambiri za mankhwalawa.

Kodi mudamvapo za dzina lakuti 'Methylene Blue'? Mwina ayi. Ndi mankhwala osowa, koma ofunikira kwambiri. Ndi madzi abuluu. Amaoneka ngati utoto womwe umapakidwa pa nsalu, koma amatha kuchiritsa matenda ena akuluakulu. Chabwino, tiyeni tiwone nkhani yake yokhudza mankhwala abuluu achilendo awa?

Kodi Methylene Blue ndi chiyani kwenikweni?

Mwachidule, methylene buluu ndi mankhwala omwe madokotala amagwiritsa ntchito pochiza matenda osowa magazi otchedwa methemoglobinemia . Ngakhale kuti ndi chinthu cholimba, chikagwiritsidwa ntchito ngati mankhwala, chimasungunuka m'madzi ndikuperekedwa ngati jakisoni ngati madzi abuluu. Mbiri ya mankhwalawa ndi yosangalatsa kwambiri. Inapezeka koyamba ndi katswiri wa zamankhwala waku Germany m'zaka za m'ma 1800. Poyamba idagwiritsidwa ntchito ngati utoto mumakampani opanga nsalu. Pambuyo pake, idagwiritsidwanso ntchito ngati utoto mu zoyeserera za labotale. Pafupifupi zaka 125 zapitazo, dokotala waku Germany adayamba kugwiritsa ntchito ngati mankhwala a malungo. Kuyambira pamenepo, ubwino wake wakula kwambiri. Pakadali pano, wavomerezedwa ndi US FDA kokha ngati mankhwala a methemoglobinemia. Komabe, madokotala nthawi zina amagwiritsanso ntchito pazifukwa zina zamankhwala.

Kodi mankhwalawa amagwiritsidwa ntchito pa matenda amtundu wanji?

Monga tanenera kale, ntchito yaikulu ya mankhwalawa ndikuchiza matenda otchedwa methemoglobinemia.

Ndiye kodi methemoglobinemia ndi chiyani?

Uwu ndi matenda okhudzana ndi magazi athu. Mwachidule, matendawa akachitika, maselo ofiira a magazi m'magazi athu sangathe kunyamula mpweya bwino kupita ku minofu ya thupi. Anthu ena amalandira matendawa kudzera m'majini, kutanthauza kuchokera kwa makolo awo. Koma kwa ambiri, matendawa amayamba chifukwa chogwiritsa ntchito mankhwala enaake, mankhwala, kapena kumwa mankhwala enaake. Methemoglobinemia ndi vuto lalikulu lomwe lingakhale loopsa ngakhale moyo . Methylene blue ndi imodzi mwa njira zabwino kwambiri zochizira matendawa.

Kodi mankhwalawa amagwira ntchito bwanji?

Methylene blue imagwira ntchito mwa kusintha mamolekyu a methemoglobin, omwe sanganyamule mpweya, kukhala mamolekyu a hemoglobin omwe amatha kunyamula mpweya. Zili ngati kuchajitsa batri. Mankhwalawa amaperekedwa ngati IV kuchipatala kapena kuchipatala ndi dokotala kapena namwino. Zimatenga mphindi 5 mpaka 30. Nthawi zambiri, mlingo umodzi umachepetsa zizindikiro. Komabe, ngati zizindikiro zikadalipo patatha ola limodzi, dokotala angasankhe kupereka mlingo wina.

Zotsatirapo zoyipa ndi kuyanjana ndi mankhwala ena

Dokotala wanu asanakupatseni mankhwala awa, adzaunikanso mbiri yanu yonse ya matenda, chifukwa mankhwalawa akhoza kukhala oopsa kwa anthu omwe ali ndi matenda enaake.

Kodi zotsatira zake ndi ziti?

Monga mankhwala ena onse, mankhwalawa akhoza kukhala ndi zotsatirapo zake.

• Zotsatirapo zazing'ono (palibe chodetsa nkhawa nacho):
• Mkodzo ndi ndowe zobiriwira ngati buluu (izi ndi zachilendo, chifukwa cha mtundu wa mankhwala)
• Kusanza ndi kusanza
• Kusintha pang'ono kwa mtundu wa khungu
• Kupweteka m'dzanja pamene anapatsidwa IV

• Zotsatirapo zoyipa zomwe ziyenera kufotokozedwa kwa dokotala nthawi yomweyo:
• Kupweteka pachifuwa
• Chizungulire
• Mutu (kupweteka mutu)
• Chisokonezo
• Kuchuluka kwa thukuta
• Kuwawa kwam'mimba

Kuyanjana kwa mankhwala

Ichi ndi gawo lofunika kwambiri. Mankhwala ena akhoza kukhala ndi zotsatira zoopsa kwambiri akamwedwa ndi methylene blue. Izi zikutanthauza kuti mankhwala otchedwa serotonin muubongo mwathu amawonjezeka kwambiri, zomwe zimayambitsa zizindikiro zoopsa monga kunjenjemera, kutentha thupi kwambiri, kutaya chidziwitso, ngakhale imfa. Chifukwa chake, ndikofunikira kuuza dokotala wanu za mankhwala onse, mavitamini, ndi zowonjezera zomwe mukumwa.

Ubwino wina ndi zinthu zochokera ku kafukufuku

Ngakhale kuti imavomerezedwa ndi FDA kokha pa methemoglobinemia, madokotala amagwiritsa ntchito pa matenda ena m'mikhalidwe yapadera. Izi zimatchedwa kugwiritsa ntchito 'off-label'.

• Monga mankhwala: Monga mankhwala ophera poizoni ndi mankhwala monga nitrite, omwe amagwiritsidwa ntchito m'mafakitale ena. Ngati mukukayikira ngati izi, pitani ku chipatala cha Emergency Treatment Unit (ETU) nthawi yomweyo. Ngati pakufunika kutero, adzayimbira National Poison Information Centre ku Colombo National Hospital kuti akalandire malangizo.
• Kugwedezeka: Kuchiza kugwedezeka kwa odwala ena omwe ali ndi vuto lalikulu omwe ali mu chipinda chosamalira odwala kwambiri (ICU).
• Kuzindikira khansa: Pa opaleshoni ya khansa, imagwiritsidwa ntchito ngati utoto wosonyeza maselo a khansa ndi ma lymph nodes mu buluu.
• Kukonza kukumbukira: Kafukufuku akuchitika kuti awone ngati izi zingakhale zothandiza pa matenda monga Alzheimer's omwe amadza ndi ukalamba.
• Monga mankhwala ophera tizilombo toyambitsa matenda:Kafukufuku wina wasonyeza kuti kuphatikiza methylene buluu ndi kuwala kungathe kupha majeremusi monga coronavirus.

Chofunika: Zambiri mwa izi zidakali mu gawo lofufuza. Choncho musayese kuziyesa chifukwa choti mwaziona pa intaneti. Nthawi zonse tsatirani malangizo a dokotala wanu. Methylene Blue, Methemoglobinemia, cyanosis, kusowa kwa G6PD, Serotonin Syndrome, Zotsatira zoyipa za mankhwala