Kodi mafupa anu akumbuyo nawonso amapweteka? Tiyeni tiphunzire za spondyloarthritis!

Kodi mumayambiranso tsiku lanu ndi msana wolimba komanso ululu mukadzuka m'mawa? Kapena nthawi zina mumamva ngati ululu wanu wamsana ukufalikira mpaka m'matako? Mungakhale osasangalala pang'ono ndi zizindikiro ngati izi. Vutoli silingakhale kupweteka kwa msana wamba. Lero tikambirana za matenda ovuta pang'ono, koma omveka bwino otchedwa Spondyloarthritis .

Kodi spondyloarthritis ndi chiyani? Mwachidule...

Mwachidule, spondyloarthritis ndi matenda a nyamakazi omwe amapezeka m'malo olumikizirana mafupa a msana wanu . "Spondyl-" amatanthauza zokhudzana ndi msana. "Arthritis" amatanthauza kupweteka ndi kuuma kwa malo olumikizirana mafupa. Matendawa amakhudza kwambiri malo olumikizirana mafupa omwe amalumikiza msana wanu. Izi zikutanthauza kuti, malo olumikizirana mafupa ang'onoang'ono pakati pa mafupa a msana ndi malo olumikizirana mafupa a sacroiliac omwe amalumikiza msana wanu ndi mafupa a m'chiuno mwanu. Ichi ndichifukwa chake kupweteka kwa msana wam'munsi nthawi zambiri kumakhala chizindikiro chachikulu . Komabe, sikuti kumakhudza msana wokha. Kungakhudze malo olumikizirana mafupa ena ndikuyambitsa zizindikiro zina.

Kumbukirani, uwu si matenda amodzi okha, koma gulu la matenda omwe ali ndi zizindikiro zofanana. Madokotala amatchanso vutoli kuti spondyloarthropathy . Limatanthauza matenda (`-pathy`) a mafupa a msana (`arthro-`). Mwina munamvapo za osteoarthritis (yomwe imayamba chifukwa cha kuwonongeka kwa mafupa) ndi rheumatoid arthritis (RA) (yomwe imayamba chifukwa cha vuto la chitetezo chamthupi). Spondyloarthritis ndi matenda osiyana ndi onse awiri, koma amathanso kukhudza mafupa a msana.

Kodi zizindikiro zazikulu za vutoli ndi ziti? Tiyeni tiwone bwino!

Pali zizindikiro zingapo zomwe zimagwirizana ndi spondyloarthritis:

• Uwu ndi matenda a nyamakazi: Spondyloarthritis ndi mtundu wa nyamakazi womwe umagwera m'gulu la matenda a nyamakazi , omwe ndi mtundu wa kutupa kwa nyamakazi . Kutupa kosatha kumayambitsa kupweteka ndi kutupa m'malo olumikizirana mafupa. Si vuto lomwe limayambitsa kuwonongeka kwa mafupa monga osteoarthritis. Nyamakazi yotupa nthawi zambiri ndi matenda odziyimira pawokha . Izi zikutanthauza kuti chitetezo cha mthupi lanu chimaukira molakwika mafupa anu, zomwe zimayambitsa kutupa kosalekeza. Kutupa kumeneku kungakhudze osati mafupa okha, komanso ziwalo zina za thupi.

• Iyi si nyamakazi ya nyamakazi (RA): Ngakhale nyamakazi ya nyamakazi ndi mtundu wa nyamakazi, iyi ndi nyamakazi ya nyamakazi (RA) yomwe tonse timaidziwa.Ayi. Tikudziwa izi chifukwa mayeso a magazi a anthu omwe ali ndi spondyloarthritis sasonyeza kuti pali antibody yotchedwa rheumatoid factor , yomwe ndi yeniyeni kwa RA. Ichi ndichifukwa chake madokotala nthawi zina amatcha vutoli kuti "seronegative spondyloarthropathy ." "Seronegative" amatanthauza kuti mayeso a magazi a RA ndi negative. Palibe antibody yeniyeni yomwe yapezeka ya spondyloarthritis (SpA).

• Enthesitis: Chizindikiro china chofunikira cha spondyloarthritis ndi kutupa (enthesitis) m'ma entheses anu . Madokotala amafufuza izi akamazindikira vutoli. Entheses ndi minofu yolumikizana ndi ulusi. Makamaka, ndi "mafupa" omwe minyewa yanu ndi mitsempha zimalumikizana ndi mafupa anu. Spondyloarthritis ingayambitse enthesitis m'mbali zosiyanasiyana za thupi. Zidendene ndi mawondo ndi malo omwe matendawa amapezeka kwambiri.

• Jini la HLA-B27: Pakati pa 80% ndi 95% ya anthu omwe ali ndi matenda a spondyloarthritis ochokera ku Northern Europe ali ndi jini la HLA-B27 . Jini ili silipezeka kawirikawiri mwa anthu omwe ali ndi matendawa m'magulu ena. Komanso, kukhala ndi jini ili sikumayambitsa matendawa okha. Komabe, ndizofala kwambiri kuti dokotala azitha kuyesa jini ili kuti athandize kuzindikira matendawa.

Kodi matendawa ndi ofala bwanji?

Ngakhale anthu ambiri sadziwa zambiri za matendawa, spondyloarthritis kwenikweni ndi matenda omwe amapezeka kwambiri kuposa nyamakazi ya rheumatoid . Akuti pafupifupi 0.5% mpaka 2% ya anthu padziko lonse lapansi ali ndi mtundu wina wa spondyloarthropathy.

Kodi mitundu ikuluikulu ya spondyloarthritis ndi iti?

Pali matenda osiyanasiyana omwe amagwera pansi pa mutu waukulu wa spondyloarthritis. Madokotala amagawa matendawa m'magulu awiri akuluakulu: axial spondyloarthritis ndi peripheral spondyloarthritis .

Matenda a nyamakazi otchedwa Axial Spondyloarthritis

Zimakhudza kwambiri mafupa a msana wanu, womwe ndi khosi, chifuwa, ndi msana . Pamene matendawa akupitirira, mafupa ena ndi ziwalo zina zimatha kukhudzidwa.

Ankylosing Spondylitis ndi mtundu woopsa wa axial spondyloarthritis. Umadziwika ndi kusintha koonekeratu m'mafupa a msana, kotchedwa ankylosis.(monga mafupa olumikizana). Kawirikawiri, uwu ndi mtundu wofala kwambiri wa spondyloarthritis.

Spondyloarthritis ya m'mphepete mwa nyanja

Mtundu uwu umakhudza koyamba mafupa anu a m'mbali ndi ziwalo zina. Izi zikutanthauza kuti mafupa omwe ali kunja kwa chigoba cha axial (monga mafupa omwe ali m'miyendo). Pamene matendawa akupitirira, msana ukhoza kukhudzidwa kapena kuwonongedwa.

Matenda a peripheral spondyloarthritis nthawi zambiri amakhudzanso kutupa m'ziwalo zina. Mitundu yosiyanasiyana imatha kukhudza ziwalo zosiyanasiyana (monga maso, khungu, ndi matumbo). Komabe, zizindikiro zake zimatha kufanana pang'ono. Mitundu ina yayikulu ndi iyi:

• Matenda a Nyamakazi a Psoriatic: Uwu ndi matenda a nyamakazi omwe amapezeka limodzi ndi psoriasis , matenda a pakhungu omwe amayambitsa kutupa pakhungu. (M'dziko lathu, izi zimatchedwanso "khungu lokhala ndi mamba"). Nthawi zambiri zimakhudza mafupa ang'onoang'ono a manja ndi mapazi, zomwe zimayambitsa kutupa ndi kupweteka m'zala.
• Matenda a Nyamakazi Okhudzana ndi Matenda a Nyamakazi: Uwu ndi matenda a nyamakazi omwe amapezeka limodzi ndi Matenda a Kutupa kwa Matumbo (IBD) . "Enteropathic" amatanthauza kuti amakhudza matumbo anu.
• Matenda a nyamakazi: Uwu ndi matenda a autoimmune omwe amachitika chifukwa cha matenda m'matumbo kapena mkodzo. Amatha kukhudza maso, khungu, chikhodzodzo, ziwalo zoberekera, kapena matumbo. Nthawi zambiri amakhala akanthawi kochepa, koma amatha kupitirira miyezi 12. Kwa anthu ena, amatha kusanduka matenda a nyamakazi osatha.

Spondyloarthritis yosasinthika

Uwu ndi matenda omwe amaperekedwa ngati zizindikiro zanu nthawi zambiri zikugwirizana ndi za spondyloarthritis, koma sizikugwirizana bwino ndi mtundu wina uliwonse.

Spondyloarthritis ya Ana

Imeneyi ndi vuto la spondyloarthritis lomwe limapezeka ali ana, nthawi zambiri asanakwanitse zaka 16. Ana amatha kukhala ndi mtundu winawake kapena kuphatikiza mitundu yosiyanasiyana.

Kodi zizindikiro za Spondyloarthritis ndi ziti?

Zizindikiro za mitundu yosiyanasiyana ya spondyloarthritis nthawi zambiri zimakhala zofanana. Ngakhale kuti zizindikiro zina zimakhala zapadera kwambiri kwa mitundu ina, zizindikiro zilizonse zimatha kuwoneka mu mtundu uliwonse.

Zizindikiro zazikulu zingakhale:

• Ululu m'munsi mwa msana, nthawi zina umafika m'matako (sacroiliitis). Kwa anthu ena, izi zingamveke ngati ululu wochokera mkati mwa fupa la m'chiuno.
• Kuuma kwa mafupa m'mawa, komwe kumachepa pang'ono mukamayenda. Zili ngati mukadzuka m'mawa, thupi lanu limamva ngati matabwa, ndipo limamasuka pokhapokha mukayenda pang'ono.
• Ululu pakati ndi pamwamba pa msana, kupweteka kwa minofu pachifuwa, kapena kupweteka pakhosi.
• Kupindika pang'onopang'ono kwa msana (monga scoliosis).
• Ululu ndi kuuma kwa malo olumikizirana ziwalo - chiuno, mapewa, mawondo, zigongono, manja, akakolo.
• Kutupa kwambiri kwa zala ("zala za soseji" kapena dactylitis). Apa ndi pamene chala chimodzi kapena chala chimodzi chimatupa kwathunthu, kuwoneka ngati soseji.
• Zizindikiro za m'mimba, mwachitsanzo, kupweteka m'mimba ndi kutsegula m'mimba.
• Ululu ndi kutupa kwa njira ya mkodzo.
• Kuyabwa, ziphuphu pakhungu (psoriasis).
• Mabowo ang'onoang'ono m'misomali (nail psoriasis).
• Kutopa kosatha.
• Chakudyacho sichikoma.
• Kutupa kwa maso (uveitis). Izi zingayambitse kufiira, kupweteka, komanso kumva kuwala.
• Zilonda pakamwa.
• Kupweteka kwa chidendene (chifukwa cha enthesitis).
• Kupanga mafupa ang'onoang'ono.

Chofunika kwambiri n'chakuti zizindikiro za spondyloarthritis nthawi zambiri zimayamba kuonekera msanga kuposa mitundu ina ya nyamakazi, nthawi zambiri munthu asanakwanitse zaka 45. Zizindikirozi zingayambe pang'onopang'ono ndipo pang'onopang'ono zimakula. Nthawi zambiri, zizindikirozi zimakhala zopitirira.

Kodi ndi zifukwa ziti zomwe zimayambitsa spondyloarthritis?

Zizindikiro za Spondyloarthritis zimayambitsidwa ndi kutupa kosatha m'mafupa anu ndi minofu ina. Kutupa kumeneku kumachitika kokha ndi chitetezo chanu cha mthupi. Ichi ndi chomwe timachitcha matenda odziyimira pawokha .

Ofufuza sakumvetsabe chifukwa chake matenda a autoimmune awa amapezeka. Komabe, zikuwoneka kuti pali zinthu zingapo zomwe zimayambitsa vutoli. Matenda ambiri a autoimmune, kuphatikizapo spondyloarthritis, amawoneka kuti ali ndi gawo la majini .

Banja la majini a HLA (Human Leukocyte Antigen) nthawi zambiri limagwirizanitsidwa ndi kutupa kwa nyamakazi. Puloteni yopangidwa ndi majini awa imagwiritsidwa ntchito ndi chitetezo chamthupi kuti iwonetse kusiyana pakati pa maselo anu ndi maselo akunja. Kusiyana kwina kwa majini awa kungayambitse kuti chitetezo chamthupi chisamagwire bwino ntchito. Izi zingayambitse kuti chitetezo chamthupi chizindikire molakwika maselo anu ndikuukira maselo anu.

Kodi ndi zinthu ziti zomwe zimayambitsa spondyloarthritis?

Ngakhale kuti pali mphamvu ya majini, si chifukwa chokhacho chomwe chimayambitsa matendawa. Ngakhale kuti anthu ambiri omwe ali ndi spondyloarthritis ali ndi jini ya HLA-B27 , si aliyense amene ali ndi jini imeneyo amene adzadwala spondyloarthritis.

Chinanso chiyenera kuyambitsa njirayi. Ofufuza ali ndi malingaliro osiyanasiyana pa zomwe zimayambitsa izi. Zina mwa izi ndi matenda oopsa, poizoni wowononga chilengedwe, kusuta fodya, ndi kumwa mowa.

Lingaliro limodzi ndi lakuti spondyloarthritis ikhoza kugwirizanitsidwa ndi kusalinganika (dysbiosis) mu microbiome ya m'mimba mwanu. Anthu omwe ali ndi spondyloarthritis (SpA) ali ndi mitundu yochepa ya tizilombo toyambitsa matenda m'matumbo, zomwe zimapangitsa kuti tizilombo toyambitsa matenda tizitha kukula mosavuta. Kusalinganika kumeneku m'matumbo (`dut dysbiosis`) kungakupangitseni kukhala pachiwopsezo chachikulu cha matenda, kuyambitsa kutupa kosatha m'matumbo, ndikufooketsa chitetezo chanu cha mthupi. Kusakanikirana kwa tizilombo toyambitsa matenda m'matumbo mwanu ndi chinthu chomwe mumatengera pamlingo winawake pobadwa.

Kodi spondyloarthritis imapezedwa bwanji?

Matenda a Spondyloarthritis amatha kukhala ovuta kuwazindikira, makamaka ngati mulibe zizindikiro zomveka bwino. Anthu ena amangomva kupweteka ndi kuuma kwa mafupa, ndipo pakhoza kukhala zifukwa zina zambiri.

Dokotala adzakufunsani kaye za zizindikiro zanu ndikuyang'ana zizindikiro zina zomwe simunatchule koma zomwe zingakhale zogwirizana nazo. Adzakufunsaninso za mbiri yanu ya thanzi komanso mbiri ya thanzi la banja lanu.

Kenako, msana wanu kapena ziwalo zina zidzawunikidwa kuti muwone momwe mungasunthire. Ma X-ray adzatengedwa kuti aone ngati pali umboni wa nyamakazi kapena enthesitis, koma umboni umenewu nthawi zonse sumawonekera pazithunzi.

Mayeso a magazi angachitikenso kuti aone ngati pali zizindikiro za kutupa kapena matenda a autoimmune. Angayesenso jini la HLA-B27 . Mayesowa angathandize kusiyanitsa spondyloarthritis (SpA) ndi matenda ena.

Kodi ndi mankhwala otani a spondyloarthritis?

Chithandizo chimadalira zizindikiro zanu. Madokotala amatsatira njira yodziwira matenda pang'onopang'ono, kuyambira ndi masewera olimbitsa thupi komanso mankhwala ochepetsa ululu omwe amaperekedwa ndi dokotala (mankhwala oletsa kutupa a OTC omwe si a steroidal / NSAIDs) .

Ngati izi sizikwanira kulamulira ululu wanu ndi kutupa, dokotala wanu angakulangizeni izi:

• Majakisoni a Cortisone amaperekedwa nthawi ndi nthawi kuti achepetse ululu womwe umapezeka m'dera linalake.
• Mankhwala a DMARD achikhalidwe kapena achilengedwe (Matenda Oletsa Matenda Oletsa Kupweteka kwa Thupi / DMARD). Awa ndi mankhwala omwe amasintha mtundu wa matendawa.

Pa mitundu ina ya spondyloarthritis, monga psoriatic arthritis ndi enteropathic arthritis, palinso mankhwala ena omwe ali enieni pa vuto lomwe limayambitsa matendawa (psoriasis kapena inflammatory bowel disease (IBD)).

Kodi vutoli ndi lalikulu bwanji? Kodi tikupita patsogolo bwanji?

Ngati kutupa kwa nyamakazi kukukula kwambiri ndipo kumatenga nthawi yayitali, mavuto ena akuluakulu amatha kuchitika. Komabe, mavutowa nthawi zambiri amakhudza moyo wanu osati moyo wanu wonse. Mwachitsanzo, mwina muli ndi kuyenda kochepa kwa mafupa komanso chiopsezo chowonjezeka cha kusweka kwa mafupa. Komabe, si aliyense amene angakhale ndi zizindikiro zoopsa, ndipo chithandizo chingathandize kuwongolera kupitirira kwa matendawa.

Kuchuluka kwa matenda a spondyloarthritis kumasiyana malinga ndi munthu. Kwa ena, amakula pang'onopang'ono ndipo amatha kuthetsedwa mosavuta ndi chithandizo. Kwa ena, amatha kupitirira kukhala ankylosing spondylitis, matenda omwe amayambitsa kusakanikirana kwa msana, mkati mwa zaka zingapo.

Kuopsa kwa kutupa kwanu kumakhudza momwe spondyloarthritis imakulira mofulumira. Kutsatira bwino chithandizo chanu kungathandize kuchepetsa kutupa ndikupewa mavuto.

Kodi mungachite chiyani mukakhala ndi spondyloarthritis?

Kwa aliyense amene ali ndi nyamakazi, kuchita masewera olimbitsa thupi nthawi zonse n'kofunika kuti mafupa aziyenda bwino momwe angathere. Madokotala ambiri amati izi ndizofunikira komanso zothandiza kuposa mankhwala ena aliwonse.

Ngati simukudziwa mtundu wa masewera olimbitsa thupi omwe ndi oyenera kwa inu, funsani dokotala wanu. Madokotala ambiri amalimbikitsa chithandizo chamankhwala chomwe chimayang'ana mafupa kapena madera enaake ovuta.

Matenda a Spondyloarthritis ndi gulu la matenda ofanana, koma osiyana. Ngakhale madokotala amawazindikira ndi kufanana kwawo, mtundu uliwonse - ndi matenda a munthu aliyense - ndi osiyana.

Kwa anthu ambiri, spondyloarthritis ndi matenda omwe amakhudza moyo wawo wonse. Komabe, momwe imakhudzira moyo wanu zimasiyana. Dokotala wanu adzakhala mnzanu wabwino kwambiri pothana ndi zizindikiro zanu komanso zomwe mungayembekezere payekha.

Zinthu zofunika kwambiri zomwe muyenera kukumbukira

Chabwino, takambirana zambiri zokhudza spondyloarthritis. Mwachidule, nazi zinthu zina zomwe muyenera kukumbukira:

• Spondyloarthritis ndi matenda a nyamakazi otupa omwe amapezeka m'malo olumikizirana mafupa a msana.
• Imeneyi ndi matenda odziteteza okha ; izi zikutanthauza kuti chitetezo cha mthupi lanu chimaukira mafupa anu.
• Zizindikiro zazikulu ndi kupweteka kwa msana (makamaka m'mawa), kuuma kwa mafupa, ndi kutupa kwa mafupa komwe minofu imalumikizana ndi mafupa.
• Jini la HLA-B27 lingakhale likukhudzidwa, koma silo lokhalo lomwe limayambitsa vutoli.
• Pali mitundu yosiyanasiyana, monga Ankylosing Spondylitis ndi Psoriatic Arthritis.
• Zizindikiro, mayeso, ndipo nthawi zina mayeso a majini amagwiritsidwa ntchito pozindikira matendawa.
• Chithandizo chimaphatikizapo kuchita masewera olimbitsa thupi, mankhwala ochepetsa ululu, komanso nthawi zina mankhwala enaake (DMARDs) .
• Kuchita masewera olimbitsa thupi nthawi zonse komanso kutsatira malangizo a dokotala ndikofunikira kwambiri kuti muthane ndi vutoli.

Ngati muli ndi zizindikiro izi, musaope kupita kwa dokotala kuti akalandire upangiri. Kuzindikira matendawa msanga ndi kulandira chithandizo kudzakuthandizani kwambiri kuti mukhale ndi moyo wabwino.

Spondyloarthritis , Spondyloarthropathy, nyamakazi ya msana, kutupa kwa mafupa, kupweteka kwa msana, matenda a autoimmune, HLA-B27, Ankylosing Spondylitis, Psoriatic Arthritis