Tiyeni tiphunzire za mankhwala a Verzenio, omwe amaperekedwa khansa ya m'mawere ikafalikira? (Khansa ya m'mawere yofalikira)

Dokotala akakuuzani kuti khansa ya m'mawere yafalikira ku ziwalo zina za thupi, kutanthauza kuti yasanduka 'yofalikira', ndikwachibadwa kumva mantha ambiri ndi nkhawa. Komabe, chifukwa cha kupita patsogolo kwa mankhwala amakono, pali mankhwala othandiza kwambiri pa milandu yotere masiku ano. Verzenio ndi imodzi mwa mankhwala otere omwe amabweretsa chiyembekezo. Chifukwa chake lero, tiyeni tikambirane mwachidule za mankhwala otchedwa Verzenio, momwe amagwirira ntchito, ndi zinthu zomwe muyenera kusamala nazo mukamazigwiritsa ntchito.

Kodi Verzenio imagwira ntchito bwanji mkati mwa thupi?

Mwachidule, Verzenio ndi mankhwala omwe ali m'gulu la mankhwala otchedwa ``kinase inhibitors``. Taganizirani ngati kuti pali ma enzyme m'thupi mwathu omwe amagwira ntchito ngati ``amithenga`` omwe amanyamula chidziwitso pakati pa maselo. Awa ndi omwe timawatcha ``kinases``. Maselo a khansa amapangidwa ndi amithenga apadera awa omwe amawauza kuti agawane ndikukula mwachangu.

Verzenio imagwira ntchito poletsa ntchito ya ma messenger otchedwa `cyclin-dependent kinases 4 ndi 6 (CDK4 ndi CDK6)`, omwe amatumiza zizindikiro ku maselo a khansa kuti akule. Kunena zoona, imaletsa mauthenga amenewo pakati pa ulendo. Mwanjira imeneyi, pamene ma enzyme a CDK4 ndi CDK6 asiya kugwira ntchito, maselo a khansa amataya chizindikiro kuti agawikane ndikukula. Zotsatira zake , kukula kwa maselo a khansa kumayima kapena kuchedwa . Izi zimathandizanso kuchepetsa zotupa.

Kodi Verzenio imagwiritsidwa ntchito pa mitundu iti ya khansa ya m'mawere?

Mankhwalawa saperekedwa pa mitundu yonse ya khansa ya m'mawere. Amagwiritsidwa ntchito makamaka pa:

• Cholandira cha mahomoni (HR) ndi chothandiza
• Cholandirira cha kukula kwa epidermal cha munthu 2 (HER2)-negative

Amagwiritsidwa ntchito pa mtundu wa khansa ya m'mawere yotchedwa khansa ya m'mawere yofalikira. Amaperekedwanso pamene khansayo yafalikira kunja kwa bere kupita ku ziwalo zina m'thupi, monga chiwindi, mapapo, kapena mafupa.

Nthawi zina mankhwalawa amaperekedwa pamodzi ndi mankhwala ena a mahomoni. Komabe, ngati khansa yafalikira ndipo matendawa sanayankhe chithandizo cha chemotherapy ndi mahomoni, Verzenio ikhoza kuperekedwa yokha . Zonsezi zimasankhidwa ndi dokotala amene akukuthandizani.

Kodi mungatenge bwanji Verzenio? Kodi muyenera kudziwa chiyani?

Verzenio ndi piritsi. Muyenera kudziwa zinthu izi mukamaigwiritsa ntchito.

• Muyenera kumwa piritsi ili kawiri patsiku .
• Mungathe kumwa musanadye kapena mutadya, koma yesani kumwa nthawi yomweyo tsiku lililonse .
• Piritsi liyenera kumezedwa lonse . Musaliswe, kuliphwanya, kapena kulitafuna.
• Musamwe mapiritsi osweka, odulidwa, kapena owonongeka.Pa nthawi imeneyo, imbani dokotala wanu ndipo mumuuze za vutoli.
• Ngati mukusanza mutamwa mankhwala, dumphani mlingo umenewo. Musamwe piritsi lina . Imwani piritsi lotsatira panthawi yomwe yakonzedwa.

Dokotala wanu adzakulangizani kuti mupitirize kumwa mankhwalawa mpaka khansa yanu itachepa kapena mpaka mutakumana ndi zotsatirapo zoyipa kwambiri. Ngati mukumana ndi zotsatirapo zina, dokotala wanu angasankhe kuchepetsa mlingo wanu, kusiya kumwa kwa kanthawi, kapena kusiya kwathunthu.

Kodi Verzenio ndi yothandiza bwanji kwenikweni? (Zotsatira za Mayeso a Zachipatala)

Mankhwalawa avomerezedwa kutengera zotsatira za mayeso angapo azachipatala omwe apambana kwambiri. Tiyeni tiwone mwachangu zotsatira za mayeso amenewo.

Kodi dokotala amawunika bwanji momwe chithandizo chikuyendera?

Mukayamba kumwa mankhwala, dokotala adzakuyang'anirani nthawi zonse.

• Kujambula: Kujambula kumachitika patatha milungu 6 kuchokera pamene munthu wayamba kumwa mankhwala kuti awone momwe khansa ikugwirira ntchito ndi mankhwalawo.
• Kuyezetsa Magazi: Izi ndizofunikira kwambiri. Kuchuluka kwa maselo m'magazi mwanu, monga maselo oyera a magazi, ma neutrophils, ndi ma platelet, kumayesedwa nthawi zonse kuti zitsimikizire kuti mankhwalawo akugwira ntchito bwino m'thupi lanu.

Kodi mungatani kuti muthane ndi zotsatirapo zake ngati zitachitika?

Zotsatirapo zoyipa zimakhala zofala ndi mankhwala a khansa. Chofunika kwambiri ndi kuuza dokotala wanu za kusintha kulikonse kapena kusasangalala komwe mukumva, ngakhale kutakhala kochepa.

• Kuyezetsa magazi nthawi zonse: Verzenio nthawi zina ingayambitse kuchepa kwa maselo oyera a magazi. Izi zimatchedwa ``neutropenia.'' Izi zingayambitse matenda aakulu. Ndicho chifukwa chake ndikofunikira kuyezetsa magazi onse omwe dokotala wanu walamula.
• Kusokonezeka m'mimba: Kusanza, kusanza, ndi kutsegula m'mimba n'kofala. Izi zitha kuthetsedwa podya zakudya zopanda mafuta ambiri, komanso kudya zakudya zazing'ono m'malo modya zakudya zazikulu. Komabe, ngati kutsegula m'mimba kwanu kuli kwakukulu, muyenera kuuza dokotala wanu nthawi yomweyo . Iye adzakupatsani upangiri wofunikira.
• Zotsatira zina zoyipa: Ngati mukukumana ndi zizindikiro zilizonse za magazi kuundana (kutupa kapena kuvulala mwendo) zomwe zimakhudza mapapu anu, monga kutsokomola, kupuma movutikira, kapena kupuma movutikira, muyeneranso kudziwitsa dokotala wanu nthawi yomweyo.

Kodi pali zinthu zina zapadera zoti mudziwe?

Inde, pali zinthu zina zingapo.

• Idyani mphesa, osati madzi: mphesa zimaletsa thupi kuwononga Verzenio. Izi zingayambitse kuchuluka kwa mankhwala m'thupi kukwera mosafunikira, zomwe zimawonjezera zotsatirapo zake.
• Mankhwala ena: Kumwa mankhwala opha mabakiteriya monga ketoconazole ndi mankhwalawa kungayambitse zotsatirapo zoopsa. Chifukwa chake, uzani dokotala wanu za mankhwala onse omwe mumamwa (kuphatikizapo mavitamini ndi zowonjezera) .
• Matenda ena:Ngati muli ndi mavuto ena azaumoyo, monga matenda a chiwindi, mlingo wanu wa Verzenio ungafunike kusinthidwa. Lankhulani ndi dokotala wanu za mbiri yanu yonse ya thanzi.