Kodi ndinu munthu amene nthawi zambiri mumadwala matenda a ziwengo? Kodi mumayamba kuyabwa mukapuma mpweya wofumbi, mumamva ziphuphu mukadya chakudya, kapena nthawi zina mumangokanda thupi lanu? Lero tikulankhula za msilikali wamng'ono koma wofunika kwambiri amene ali kumbuyo kwa zinthu zonsezi. Mwina mwawonapo mawu oti 'Basophils' m'magazi anu, kutanthauza kuti, mu 'Full Blood Count'. Ndiye, kodi ma basophils awa ndi chiyani? Nchifukwa chiyani matupi athu amawafuna? Tiyeni tikambirane za izi m'njira yosavuta kumva.
Kodi basophil kwenikweni ndi chiyani?
Mwachidule, ma basophil ndi mtundu wa maselo oyera a magazi (`Maselo Oyera a Magazi` - WBC) m'magazi mwathu. Tangoganizani kuti thupi lathu lili ngati dziko. Ndiye maselo oyera a magazi ndi mphamvu yoteteza dziko lino. Pali mphamvu zosiyanasiyana mu mphamvu iyi. Chifukwa chake, pali mitundu isanu ya maselo oyera a magazi. Ma basophil ndi ochepa kwambiri mwa mitundu isanu, zomwe zikutanthauza kuti ndi mphamvu yosowa kwambiri.
Mkati mwa maselo a basophil awa muli tinthu tating'onoting'ono. Tinthu tating'onoting'onoti timadzazidwa ndi mankhwala ofunikira kwambiri otchedwa histamine. Histamine iyi imayambitsa kuyabwa, kufiira maso, ndi mphuno zomwe mumapeza mukakhala ndi vuto la ziwengo. Ma basophil amathandizanso kuteteza matupi athu ku tizilombo toyambitsa matenda komanso kuchiritsa mabala .
Kapangidwe ndi makhalidwe a basophils
Makhalidwe amenewa a basophils ndi ofunikira kwambiri kwa madokotala kuti adziwe matenda enaake. Tiyeni tiwone zina mwa zinthu zokhudza msilikali wamng'ono uyu.
| Khalidwe | Kufotokozera |
|---|---|
| Kukula | Izi ndi zazing'ono kwambiri, pafupifupi ma micrometer 5-10 (µm) kukula. |
| Maonekedwe ndi mtundu | Mukapaka utoto wapadera (Wright-Giemsa stain), tinthu tating'onoting'ono tomwe timadzaza ndi histamine mkati mwa maselowa timaoneka ngati utoto wakuda. Tinthuti timatha kuzindikirika mosavuta pogwiritsa ntchito maikulosikopu. |
| Malo osungira maselo (Nucleus) | Pakati pa selo nthawi zambiri pamakhala ngati chilembo 'S'. |
| Moyo ndi kubadwa | Ma basophil amapangidwa m'mafupa mkati mwa mafupa athu. Akapangidwa kumeneko, amakhala ndi moyo kwa maola pafupifupi 60 okha atalowa m'magazi. |
| Zizindikiro Zapamwamba | Mapuloteni ena apadera pamwamba pa maselo awa (monga `CD-123`, `CD-193`) amathandiza madokotala kuzindikira matenda monga khansa zina za m'magazi (`Leukemia`). |
Kodi ma basophil amapereka chithandizo chotani m'thupi lathu?
Ntchito yaikulu ya ma basophils ndikutulutsa histamine yomwe tidakambirana kale. Koma kuwonjezera apo, maselo ang'onoang'ono awa amagwira ntchito yabwino kwambiri m'matupi athu.
- Chitetezo ku Allergens : Zinthu monga fumbi ndi mungu zikalowa m'thupi, zimalimbana nazo.
- Kulimbana ndi tizilombo toyambitsa matenda: Izi zimayambitsidwa panthawi ya matenda opatsirana monga mphutsi .
- Kuchira kwa mabala : Kumathandiza pakuchira mabala.
- Kuletsa magazi kuundana: Maselo amenewa amatulutsanso mankhwala otchedwa heparin, omwe amathandiza kusungunula magazi kuundana osafunikira.
Ubale pakati pa ziwengo ndi basophils
Tangoganizirani udzudzu ukuluma dzanja lanu. Patapita kanthawi, malowo amakhala ofiira, otupa, komanso oyabwa kwambiri, sichoncho? Ndicho chimene histamine, yomwe imachokera ku basophils, imachita.
Chomwe histamine imachita ndikuwonjezera kuyenda kwa magazi m'derali. Izi zimabweretsa magazi ambiri m'derali, "kutsuka" magaziwo, kuthandiza kuchotsa zinthu zomwe zimayambitsa allergen. Kutupa ndi kutupa kumeneku ndi gawo la njira yochiritsira.
Pamene allergen ikalowa m'thupi la munthu amene ali ndi allergy, chitetezo cha mthupi chimapanga mtundu wa antibody wotchedwa Immunoglobulin E (IgE). IgE iyi imapita ndikumangirira ku allergen. Kenako ma basophils amabwera ndikumenyana ndi IgE-allergen complex iyi, ndikutulutsa histamine yonse yomwe ili mkati mwake. Pamenepo ndi pomwe mumapeza zizindikiro za allergy.
- Mphuno yotuluka madzi, kutsekula
- Maso ofiira, oyabwa
- Kuyabwa pakhosi
- Kutupa pakhungu, kuyabwa
- Kuvuta kupuma mwa odwala mphumu
Kodi mumayesa bwanji kuchuluka kwa basophil m'magazi anu?
Ngati dokotala wanu akulamulani kuti muyesedwe `Complete Blood Count (CBC)`, kapena monga momwe timatchulira, `full blood calculator`, chiwerengero cha basophil chidzalembedwanso pa lipotilo. Izi zitha kuphatikizidwa mu lipotilo m'njira ziwiri.
1. Monga peresenti (%): Kodi ndi peresenti iti ya maselo oyera onse omwe ndi basophils? Kawirikawiri iyi ndi mtengo wochepa kwambiri, pafupifupi 0.5% - 1%.
2. Chiwerengero Chokwanira: Chiwerengero chenicheni cha ma basophil pa mililita imodzi ya magazi.
Chofunika kwambiri ndikuyerekeza mtengo wanu ndi gawo la 'Normal Range' kapena 'Reference Range' pa lipoti lanu la labu, chifukwa mtengo wabwinobwinowu ungasiyane pang'ono kutengera makina omwe amagwiritsidwa ntchito mu labu iliyonse.
| Mulingo | Tanthauzo |
|---|---|
| Kuwerengera Kwabwinobwino | Pakati pa 0.5% - 2% ya maselo oyera a m'magazi. Mtengo wokwanira nthawi zambiri umakhala pakati pa 0.01 x 10⁹/L mpaka 0.08 x 10⁹/L. |
| Kuchuluka kwa magazi (Basophilia) | Miyezo ya basophil ndi yokwera kuposa yachibadwa. |
| Mlingo wotsika (Basopenia) | Miyezo ya Basophil ikutsika pansi pa muyezo wabwinobwino. |
Kodi kuchuluka kwa basophilia (basophilia) n'koopsa?
Kuwonjezeka kwa kuchuluka kwa basophil m'thupi kumadziwika ndi madokotala kuti ``Basophilia.'' Pakhoza kukhala zifukwa zingapo zomwe zimapangitsa izi.
- Matenda a ziwengo: Matenda a ziwengo ku zinthu monga chakudya, mankhwala, fumbi, ndi zina zotero.
- Matenda: Matenda ena monga nkhuku ndi chimfine.
- Mavuto a chithokomiro: Kuchepa kwa mahomoni a chithokomiro (`Hypothyroidism`).
- Matenda a pakhungu: Matenda a pakhungu ofanana ndi a eczema monga atopic dermatitis.
- Matenda a magazi: Matenda monga polycythemia vera.
- Matenda ena a khansa: Khansa ya m'magazi monga khansa ya m'magazi yosatha (CML).
Musachite mantha ndi mndandandawu. Nthawi zambiri, kuchuluka kwa basophil m'thupi kumatha kukhala chifukwa cha vuto losavuta monga ziwengo wamba. Koma muyenera kusiya dokotala wanu kuti adziwe chomwe chimayambitsa matendawa. Iye adzachita mayeso ena ngati pakufunika kutero kuti atsimikizire chomwe chimayambitsa matendawa.
Kodi basopenia ndi chiyani?
Kuchepa kwa kuchuluka kwa basophil kumatchedwa ``Basopenia``. Izi ndizosowa kwambiri kuposa ``Basophilia``. Izi zithanso kuchitika chifukwa cha zifukwa zingapo.
- Matenda ena.
- Kupanga kwambiri mahomoni a chithokomiro (`Hyperthyroidism`).
- Matenda oopsa komanso omwe amayamba nthawi yomweyo (`Anaphylaxis`).
- Matenda ena a chitetezo chamthupi, monga `Systemic Lupus Erythematosus (SLE)`.
Kuchepa kwa ma basophil kungathandizenso kuti mabala athu apole.
Nthawi yoti mupeze upangiri wachipatala nthawi yomweyo
Ngakhale kuti ziwengo wamba si zoopsa, nthawi zina chitetezo cha mthupi chimatha kuchita zinthu mopitirira muyeso. Izi zimatchedwa `Anaphylaxis`.
Anaphylaxis ndi vuto lachipatala lomwe lingayambitse imfa. Ngati inu kapena wina akukumana ndi zizindikiro zotsatirazi, pitani ku dipatimenti yapafupi yadzidzidzi ya chipatala (ETU) nthawi yomweyo.
- Kutupa kwa milomo, lilime, kapena nkhope
- Kuvuta kupuma
- Kuvuta kumeza
- Ziphuphu kapena kufiira kwa khungu lonse thupi lonse
- Kupweteka m'mimba, kusanza, kapena kutsegula m'mimba
- Kulimba pachifuwa kapena phokoso la mluzu
- Kumva chizungulire kapena kukomoka
Nthawi ngati izi, ndikofunikira kwambiri kuti musachite mantha ndikupita kuchipatala nthawi yomweyo.
Uthenga Wopita Nawo Kunyumba
- Ma Basophil ndi mtundu wofunikira wa maselo oyera m'thupi lathu omwe amalimbana ndi ziwengo ndi matenda opatsirana.
- Histamine, yomwe imatulutsa ndi iwo, ndiye chifukwa cha zizindikiro zambiri za ziwengo, monga kuyabwa ndi kutupa.
- Ngati mulingo wanu wa basophil m'magazi anu uli pamwamba pa mulingo woyenera, musachite mantha ndipo lankhulani ndi dokotala wanu. Nthawi zambiri chifukwa chake chingakhale chinthu chosavuta.
- Ngati mukukumana ndi zizindikiro zoopsa za ziwengo monga kuvutika kupuma komanso kutupa nkhope, ndi zadzidzidzi. Pitani ku Dipatimenti Yothandiza Anthu Odwala Zadzidzidzi (ETU) ya chipatala nthawi yomweyo.
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