Cholecystokinin ni iki? Reka tubiganireho mu buryo bworoshye!

Muraho! Mumeze mute? Uyu munsi tugiye kuvuga ku kintu gito ariko gifite akamaro kanini mu mubiri wacu. Cyitwa cholecystokinin. Nubwo izina rishobora gusa nkaho ari rirerure, ni ingenzi mu mikorere yacu y'igogora. Reka turebe icyo gikora, uko gikora, n'akamaro kacyo ku mubiri wacu?

Iyi cholecystokinine ni iki?

Mu magambo make, cholecystokinin ni imisemburo . Ese uzi imisemburo? Ni nk'intumwa nto zitwara ubutumwa ahantu hamwe na hamwe mu mibiri yacu. Iyi misemburo yitwa cholecystokinin ikorwa ahanini n'uturemangingo two mu mara mato , cyane cyane iyo tumaze kurya. Niyo mpamvu rimwe na rimwe yitwa pancreozymin. Yiswe gutyo kuko ikora muri pancreas. Ariko igitangaje ni uko iyi cholecystokinin iboneka no mu bwonko bwacu no mu bwonko bwacu . Abahanga mu bya siyansi baracyashakisha neza icyo ikora aho. Ariko uruhare rwayo mu igogora ni runini cyane.

Ni gute cholecystokinin itangira gusohoka?

Tekereza ko wariye ifunguro riryoshye. Wenda inyama zirimo umuceri, cyangwa agace k'ifi, lentile, sambol y'ikokonati... Ibiryo urya bibanza kujya mu nda. Bigagogorwa aho igihe gito, hanyuma buhoro buhoro bigatangira kugera ku gice cya mbere cy'amara mato, duodenum . Bimeze nka gari ya moshi igera kuri sitasiyo. Hanyuma, hari uturemangingo twihariye mu nkuta za duodenum yawe, nk'abashinzwe iperereza. Bitwa uturemangingo twa I. Utwo turemangingo twa I dufite ubushobozi butangaje bwo kumenya poroteyine n'ibinure (ni ukuvuga inyama, amafi, amagi, amata, amavuta) mu biryo urya. Bakimara kubibona, utwo turemangingo twa I (I-cells) twibwira tuti: "Oh, iki ni cyo gihe cyo gutangira akazi! Tugomba gukuramo inshuti yacu cholecystokinin vuba," maze bakayikora bakayirekura mu maraso. Kuva aho, urugendo rwayo rw'ingenzi ruratangira.

Ni iki cholecystokinin ikora ku mubiri wacu?

Aha niho akazi nyakuri kabera nyuma y’uko cholecystokinine yinjiye mu maraso. Ntabwo iguma aho gusa, inyura mu maraso, ikajya kuri buri rugingo, kandi igakora imirimo myinshi y’ingenzi.

Icyo bikora mu gihe cyo kugogora

Reka turebe akamaro k'uruhare rwa cholecystokinin mu igogora:

• Bituma agasabo k'inkari gafata: Bibwira agasabo kawe kiti "Sawa, noneho ufite inyo imbere muri wowe."Shyira mu mara mato. Igihe kirageze ngo dukore!" Ntutangare, izina 'cholecystokinin' risobanura 'kwimura agasabo k'inkari'. Iyi nyo ni yo ifasha gushonga amavuta, cyangwa ibinure, turya, no kuyamenagura mo udutonyanga duto. Nk'uko dukoresha isabune mu koza amasahani.
• Ikangura pancreas: Yohereza kandi ikimenyetso kuri pancreas, igira iti: "Ugomba kandi kohereza enzymes zawe zo mu gifu mu mara mato. Hari akazi gakomeye ko gukora hano." Irindi zina, "pancreozymin," rikomoka kuri iki gikorwa kijyanye na pancreas .
• Poroteyine n'ibinure bicika: Inyo iva mu gasabo k'inkari n'imisemburo iva mu gasabo k'inkari bikora hamwe kugira ngo bigabanye poroteyine n'ibinure biri mu biribwa turya mo uduce duto kugira ngo umubiri ubigeremo. Ibi ni nko kumena ibuye rinini mo uduce duto.
• Igenzura isohoka ry'igifu : Mu gihe iki gikorwa kirimo gukorwa mu mara mato, cholecystokinin ibwira igifu iti "Wihangayika, tegereza gato. Ntukohereze itsinda rishya ry'ibiryo mu mara mato kugeza igihe ibiryo byabanje bizigabuwe." Ibi byitwa guhosha isohoka ry'igifu . Ibi bivuze ko amara mato atabona ibiryo byinshi icyarimwe, ahubwo afite umwanya wo kubigogora neza.
• Igabanya ubushake bwo kurya : Mu gihe cyo kugogora, cholecystokinin ituma igifu cyacu cyuzura. Ikangura kandi imitsi yo mu nda iri mu rukuta rw'igifu, yohereza ubutumwa ku bwonko bugira buti "Ndahaze, ndahaze, ntukongere kurya." Niyo mpamvu twumva duhaze nyuma gato yo kurya.
• Peristalsis iratangira: Amaherezo, iki giryo cyagabuwe kigomba kwimurwa mu mara . Ibi bifashwa no kwihuta kw'imitsi yo mu mara no kuruhuka kw'imitsi yo mu mara, byitwa peristalsis . Ni nko gusunika ibiryo mu mara .

Tekereza uburyo iyi hormone imwe ifasha mu buryo bworoshye inzira yacu yo gusya!

Ingaruka ku bwonko no ku mikorere y'imitsi

Uretse gufasha mu igogora, cholecystokinin yagaragaye ko igira uruhare mu bwonko bwacu no mu mitsi yo hagati. Ibi biracyakorerwa ubushakashatsi, ariko ibyavumbuwe kugeza ubu ni ingenzi cyane. By'umwihariko, bishobora gufasha mu kugabanya imihangayiko noBisa nkaho bifitanye isano n'indwara zo mu mutwe nko gucika intege . Ubushakashatsi bumwe bwagaragaje ko kwiyongera kwa cholecystokinine mu bwonko byongera imihangayiko. Ibi biragoye gato, ariko biragaragara ko bigira ingaruka ku mikorere yacu y'amarangamutima. Byavuzwe kandi ko bigira uruhare mu kugenzura ubushyuhe bw'umubiri, cyangwa ubwiyongere bw'ubushyuhe . Bivugwa ko iyo bishyizwe mu bwonko, bizatera umuriro, kandi iyo bishyizwe mu bindi bice by'umubiri, bizatera hypothermia, indwara ituma ubushyuhe bw'umubiri bugabanuka. Ariko, hakenewe ubushakashatsi bwimbitse kugira ngo tubisobanukirwe neza.

Ni hehe ho mu mubiri wacu haboneka cholecystokinin?

Kimwe n'izindi misemburo, cholecystokinin inyura mu mibiri yacu mu maraso yacu. "Ivugana" n'ingingo zitandukanye binyuze mu buryo bwihariye bwo kwakira amakuru ku turemangingo tw'izo ngingo. Izi receptor zimeze nk'inzugi. Iyo urufunguzo rwitwa cholecystokinin ruhari, ni bwo inzugi zifunguka, hanyuma ingirabuzimafatizo zigakira ubutumwa. Mu buryo bwacu bwo gusya, receptor za cholecystokinin (CCK) ziboneka mu mitsi y'agasabo k'inkari, mu gifu no mu mara, no mu impyiko. Izi receptor zishobora kandi kuboneka mu bice bitandukanye by'ubwonko no mu bwonko.

Ni izihe ndwara zifitanye isano na cholecystokinin?

Hari indwara zimwe na zimwe zagaragayemo urugero ruto rwa cholecystokinin. Ariko, ntibiramenyekana neza niba ibi ari ingaruka z'iyi ndwara cyangwa impamvu yayo. Ubushakashatsi buracyakomeje kuri ibi. Urugero, urugero ruto rwa cholecystokinin rushobora kuba rufitanye isano n'indwara nka gastroparesis , indwara aho igifu kidasohora neza kandi ibiryo bigafata, na dyskinesia y'inkari, indwara aho agasabo k'inkari kadakora neza kandi inyo idashobora gusohoka neza. Byongeye kandi, abahanga mu bya siyansi barimo gukora ubushakashatsi ku buryo itandukaniro ritandukanye mu ngirabuzimafatizo zigize uruhare mu ikorwa rya cholecystokinin rifitanye isano n'indwara zimwe na zimwe zo guhangayika n'ibibazo by'imikorere y'umubiri. Ubushakashatsi bumwe bwerekana ko ubwo bwoko bw'ingirabuzimafatizo bushobora guhindura uburyo cholecystokinin ikorana n'ubwonko kandi ikagenzura ibimenyetso by'ubwoba cyangwa inzara.

Ni iyihe sano iri hagati ya cholecystokinin n'umubyibuho ukabije?

Umubyibuho ukabije, cyangwa umubyibuho ukabije, ni ikibazo ku bantu benshi muri iki gihe. Abahanga mu bya siyansi nabo barimo gukora iperereza ku buryo bufatika niba hari isano iri hagati y’umubyibuho ukabije na cholecystokinin. Bimwe mu byavumbuwe biratangaje cyane. Urugero, byagaragaye ko abantu bafite impinduka runaka (impinduka) muri gene ya cholecystokinin bafite amahirwe agera kuri 60% yo kubyibuha kurusha abandi. Hari kandi ibimenyetso bimwe na bimwe bigaragaza ko abantu bafite umubyibuho ukabije cyane (umubyibuho ukabije wo mu cyiciro cya gatatu), ni ukuvuga abantu babyibushye cyane, bafite ubushobozi buke bwo kumva cholecystokinin. Ibi bivuze ko nubwo bafite cholecystokinin mu mibiri yabo, bashobora kutabasha kumva neza ikimenyetso cy ''ibyuzuye' ibaha. Cholecystokinin ikorana n'indi misemburo yitwa leptin kugira ngo igenzure inzara. Abantu bafite umubyibuho ukabije bashobora kugira ubusumbane hagati y'ibimenyetso by'inzara n'ibyuzuye mu bwonko bwabo. Kubwibyo, gusobanukirwa cholecystokinin nabyo bishobora gufasha mu gushaka uburyo bwo kuvura umubyibuho ukabije.

Iki kizamini cya cholecystokinin ni iki?

Ikizamini cya cholecystokinin gikubiyemo guha agasabo k'inkari umuti witwa cholecystokinin kugira ngo kagakure. Hari igihe ibi bikorwa nk'igice cya scan ya HIDA, ari na yo suzuma ryihariye ry'imiti ya kirimbuzi . Ntugahangayikishwe n'izina, iki ni ikizamini cyizewe cyane. Dore uko bigenda: 1. Ubwa mbere, umutekinisiye ashyiramo agace gato ka radioactive isotope, cyangwa tracer, mu mitsi yawe. Ni nko gushushanya imihanda mike mu mubiri wawe no kureba ibirimo kuba. 2. Iyi tracer ijya mu mwijima wawe no mu nzira y'inkari (gallbladder, biliary ducts). 3. Hanyuma, kamera yihariye (scanner) ikoreshwa mu gufata imirasire iva muri iyi tracer no kwerekana amashusho kuri ecran ya mudasobwa. Aya mashusho yemerera umuganga kureba uko inyo ikorwa n'uko igenda. Niba umuganga wawe ashaka kureba uko inyo igenda iyo inyo yawe irakuruye, ashobora kongeramo cholecystokinin muri scan ya HIDA nk'intambwe y'inyongera. Muri icyo gihe, umutekinisiye azashyira cholecystokinin mu mitsi yawe. Hanyuma, hafatwa andi mashusho. Kimwe na cholecystokinin ikorerwa mu mara yawe mu buryo busanzwe, cholecystokinin yatewe itera imyuka gufunga. Abaganga bategeka iki kizamini kugira ngo barebe niba hari ikibazo mu mikorere y'imyanda yawe kandi niba isohora imyuka neza.

Ese hari uburyo bwo kuvura indwara ya cholecystokinin?

Kugeza ubu, nta buvuzi buhari bukoresha cholecystokinin mu buryo butaziguye. Ni ukuvuga ko cholecystokinin idatangwa nk'umuti w'indwara. Ariko, yakoreshejwe mu kuvumbura no kugerageza imiti mishya. Urugero, abashakashatsi barimo kugerageza gukora imiti isa na cholecystokinin mu kugabanya ubushake bwo kurya no gufasha mu kugabanya ibiro. Nanone, cholecystokinin ifite igice cyihariye cyitwa CCK-4 . Iyi CCK-4 izwiho gutera abantu guhangayika no kugira ubwoba. Kubwibyo, abahanga rimwe na rimwe bakoresha CCK-4 kugira ngo bapime uburyo imiti mishya igabanya guhangayika ifite akamaro.

Ibintu by'ingenzi tugomba kwibuka (Ubutumwa bwo kujyana mu rugo)

Rero, uhereye ku byo twavuze kuri cholecystokinin, ushobora kwibuka bimwe mu bintu by'ingenzi cyane. Noneho usobanukiwe uburyo iyi hormone nto ikora mu mibiri yacu, sibyo?

• Cholecystokinin ni imisemburo y'ingenzi mu igogora . "Ivugana" n'ingingo zose zigize uruhare mu igogora, nk'agasabo k'inkari na pancreas, kandi ikabafasha gukora akazi kabo neza.
• Abaganga banayikoresha nk'ikintu cyizewe cyo gupima imikorere y'agasabo k'inkari.
• Binafasha mu kugenzura inzara . Byagaragaye kandi ko imikorere mibi ya cholecystokinin ishobora kuba ifitanye isano n'indwara nk'umubyibuho ukabije.
• Abahanga mu bya siyansi bakomeje kwiga uruhare rwayo mu bwonko no mu mikorere y’ubwonko, cyane cyane isano ifitanye n’indwara nk’imihangayiko n’ibibazo by’ubwoba.

Rero, imibiri yacu ni imashini zitangaje! Biratangaje ukuntu ibi bintu bito bishobora kugira ingaruka ku buzima bwacu, si byo se? Wite ku mubiri wawe, kandi izi nshuti nto zizakwitaho!

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Cholecystokinin, Cholecystokinin, Imisemburo, Igogora, Indwara y'agahinda, Pancreas, Inzara, Umubyibuho ukabije, HIDA scan