Acromegaly: Ese amaguru n'isura byawe binini bidasanzwe? Reka tuganire!

Ese wigeze ubona ko imiterere y'amaboko, amaguru, cyangwa isura yawe irimo guhinduka? Wenda impeta wambara akenshi ikumva igufashe, cyangwa ingano y'inkweto zawe yarahindutse? Ibi si ibintu bitunguranye gusa, bishobora kuba ibimenyetso by'indwara idasanzwe ariko ishobora kuba ikomeye yitwa acromegaly . Ntugahangayike, tuzabivugaho birambuye kandi uyu munsi.

Acromegaly ni iki? Mu magambo make...

Acromegaly ni indwara iterwa n'urugero rwinshi rw'ibinyabutabire byitwa Growth Hormone (GH) mu mubiri wawe. Ubusanzwe, iyi hormone yo gukura (GH) ikorwa na pituitary gland , icyuma kingana n'amashaza kiri mu nsi y'ubwonko bwacu. Ariko, muri acromegaly, iyi hormone ikorwa cyane bitewe n'ikibyimba mu gisabo cya pituitary cyangwa ahandi hantu mu mubiri.

Ese wari uzi ko agahu k'ubwonko ari agahu gato ariko gafite akamaro cyane. Gasohora imisemburo umunani, imwe muri yo ikaba ari imisemburo yo gukura (GH).

Imisemburo yo gukura (GH) ni iki kuri twe?

Imisemburo yo gukura, izwi kandi nka Human Growth Hormone (hGH) cyangwa Somatotropin , ni imisemburo karemano. Ni ingenzi ku mikurire y'ibice bitandukanye by'umubiri wacu no ku mikurire y'uburebure mu bwana. Ariko, uko tugenda dukura, nyuma y'uko epiphyses z'amagufwa yacu zifunze, imibiri yacu iracyakeneye iyi GH. Uzi impamvu? Ifasha kubungabunga imiterere myiza y'amagufwa yacu, cartilage, n'ingingo z'imbere, kandi igafasha mu kugena imikorere myiza y'umubiri, cyane cyane urugero rw'isukari mu maraso.

Rero, iyo imisemburo y’umubiri (GH) yiyongera cyane nyuma yo gukura, ibibazo nko kubura imiterere y’amagufwa, kwaguka kw’ingingo, no kwiyongera kw’isukari mu maraso (hyperglycemia) bishobora kubaho.

Ni irihe tandukaniro riri hagati ya Acromegaly na Gigantism?

Byombi biterwa n'ubwiyongere bw'imisemburo itera gukura (GH). Ariko, itandukaniro riri mu bantu iyo ndwara ifata. Abantu bakuru barwara acromegaly. Abana barwara gigantism .

Iyo urugero rw'imisemburo itera imbere (GH) rwiyongereye mu bana mbere y'uko ibice by'igufwa byabo bifunga (ni ukuvuga mbere y'uko ubwangavu burangira), bazakura barebire cyane. Ibi byitwa gigantism. Ni gake cyane kurusha acromegaly. Hari abaganga banabyita "acromegaly y'abana."

Ariko, niba urugero rw'imisemburo yo gukura (GH) rwiyongereye nyuma y'uko imirongo y'imyanya ...

Ni nde ushobora cyane kurwara acromegaly?

Ishobora kugaragara mu myaka iyo ari yo yose nyuma y'ubugimbi. Ariko, abaganga bakunze kuyisuzuma ku bantu bari hagati y'imyaka 40 na 50, ni ukuvuga mu myaka yo hagati.

Ibi ni ibisanzwe gute?

Acromegaly mu by'ukuri ni indwara idakunze kugaragara . Abantu bagera kuri 31 mu 100.000 ni bo bonyine basanzwe bafite iyi ndwara. Rero ntugatinye bitari ngombwa, ariko ni ngombwa kumenya ibimenyetso byayo.

Ni gute acromegaly igira ingaruka ku mubiri wanjye?

Iyo umuntu mukuru agize acromegaly, ni ukuvuga iyo hari ukwiyongera kwa hormone yo gukura (GH), amagufwa, cartilage, ingingo z'umubiri, n'izindi ngingo zitangira kwiyongera mu bunini. Hariho impinduka zigaragara mu miterere . Urugero:

• Kwagura amaboko n'ibirenge.
• Kwagura amatwi, iminwa n'amazuru.
• Umusaya ugaragara, agahanga kanini.

Imisemburo yo gukura (GH) imenyesha umwijima wacu gukora indi misemburo yitwa Insulin-like Growth Factor 1 (IGF-1) . Iyi misemburo yitwa IGF-1, mu by'ukuri ifasha amagufwa yacu n'ingingo z'umubiri gukura, kandi inagira ingaruka ku buryo umubiri wacu ugenzura isukari mu maraso (glucose) n'ibinure (lipide). Rero, iyo urugero rwa GH rwiyongereye, urugero rwa IGF-1 narwo ruriyongera. Ibi bishobora gutera indwara nka Diyabete yo mu bwoko bwa 2 , umuvuduko ukabije w'amaraso (umuvuduko ukabije w'amaraso) , n'indwara z'umutima .

Tekereza gato, kimwe n'uko robine isigaye itemba igihe kirekire itakaza amazi, iyo irenze urugero, iyi misemburo igira ingaruka zitandukanye ku mubiri.

Ni izihe mpamvu zitera acromegaly?

Impamvu ikunze gutera acromegaly ni ikibyimba kiri mu gahu k'ubwonko. Ibi byitwa adenoma ya pituitary . Iyi kibyimba ituma agahu k'ubwonko gasohora imisemburo myinshi cyane (GH).

Birenzeho gato kuri Adenoma y'umuyoboro w'amaraso...

Izi ndwara zo mu bwonko zikunze kuba mbi. Ni ukuvuga ko atari kanseri. Ibyinshi mu bibyimba bitera acromegaly bikura buhoro buhoro. Bityo, ushobora kutabona ibimenyetso by'iyi GH irenze urugero mu gihe cy'imyaka myinshi.

Bitewe n'ingano n'aho ikibyimba giherereye, gishobora kwisunika ku bindi bice by'agahu k'ubwonko no kugira ingaruka ku yindi misemburo ikorwa n'agahu k'ubwonko. Iyo ikibyimba ari kinini, gishobora no kwisunika ku bice byegereye ubwonko, bigatera kuribwa umutwe no kutabona neza .

Ni ibihe bimenyetso bya Acromegaly?

Iyo umuntu mukuru agize ikibazo cyo kubura amaraso, bigira ingaruka ku magufwa n'ingingo z'umubiri, bigatuma zikura mu buryo budasanzwe. Ibi bishobora gutera ibimenyetso bikurikira:

• Amaboko cyangwa ibirenge byagutse: Wenda impeta zawe zitangira gufungana, kandi ingano y'inkweto zawe, cyane cyane ubugari, irazamuka.
• Impinduka mu miterere y'isura: Kugaragara cyangwa kwaguka k'agasaya n'agahanga.
• Kwaguka kw'iminwa, izuru, n'ururimi.
• Kubira ibyuya byinshi cyangwa uruhu rufite amavuta menshi.
• Ijwi rirushaho kwiyongera no gushyuha.

Ibindi bimenyetso:

• Kuribwa umutwe
• Ububabare bw'ingingo
• Impinduka mu cyerekezo
• Ukwiyongera kw'udutambaro tw'uruhu duto
• Ubumuga mu ntoki
• Uruhu rwo mu mutwe ruterwa no kubura umwuka wo mu mutwe igihe umuntu asinziriye (sleep apnea)
• Indwara ya Carpal tunnel cyangwa ibibazo by'umugongo.

Ibimenyetso bya acromegaly bikunze kwiyongera buhoro buhoro , rimwe na rimwe mu gihe cy'imyaka myinshi. Bityo rero bishobora kugorana kubimenya mu ntangiriro. Hari abantu babona ko amaboko yabo yabaye manini iyo impeta bambara ibaye ikomeye cyangwa ingano y'inkweto zabo ihinduka.

Tekereza, hari umuntu witwa Nilanthi. Amaze igihe yumva impeta ye y'ubukwe imufashe nk'aho imufashe. Inkweto ze ntizimufashe nk'uko byari bisanzwe, ziramufashe gato. Yibwiraga ko amaze gukura. Ariko icyarimwe, inshuti ze zivuga ko isura ye itandukanye gato n'iya mbere, kandi akananwa ke kakaba kanini gato. Utu ni utuntu duto tugaragara mbere.

Niba ufite ibi bimenyetso, ni ngombwa cyane kuvugana na muganga.

Acromegaly ipimwa ite?

Kubera ko ibimenyetso bigaragara buhoro buhoro, mu myaka myinshi, bishobora kugorana kubisuzuma.

Muganga wawe ashobora kukwohereza kwa muganga w’indwara z’imitsi , umuganga wihariye mu ndwara ziterwa n’imisemburo. Azagusuzuma akurikije amateka y’ubuzima bwawe, isuzuma rya muganga, n’ibizamini byihariye (nk’ibipimo by’amaraso n’ibizamini byo gufata amashusho).

Ni ibihe bipimo byo gusuzuma indwara?

Iyo ufashwe na acromegaly, muganga wawe ashobora gusaba ko ukorerwa ibindi bipimo kugira ngo arebe niba iyi ndwara yaragize ingaruka ku bindi bice by'umubiri wawe. Ibi bishobora kuba birimo:

• Ikizamini cya echocardiogram kugira ngo harebwe niba hari ibibazo by'umutima.
• Ibizamini byo kwiga ibitotsi kugira ngo harebwe niba uri kubura umwuka mu gihe usinziriye.
• Colonoscopy kugira ngo harebwe ubuzima bw'amara.
• Reba ubuzima bw'amagufwa ukoresheje X-ray cyangwa DEXA scan .

Acromegaly ivurwa ite?

Hari uburyo butandukanye bwo kuvura acromegaly. Bitewe n'ibimenyetso byawe n'uko umerewe, muganga wawe azagusobanurira uburyo bwo kuvura bukubereye.

Uburyo bukunze gukoreshwa cyane ni ubu:

• Kubaga
• Umuti
• Ubuvuzi bushingiye ku mirasire

Kubaga Acromegaly

Kenshi na kenshi, kubaga bishobora kugabanya cyane cyangwa gukiza burundu ibimenyetso bya acromegaly. Abaganga babaga akenshi bakoresha uburyo bwitwa transsphenoidal surgery , bukubiyemo kubaga binyuze mu mazuru no muri sphenoid sinus (ahantu hari ubucucike inyuma y'izuru, munsi y'ubwonko).

Ibisobanuro birambuye ku kubagwa biterwa n'ingano n'aho ikibyimba giherereye. Intego nyamukuru yo kubagwa ni ugukuraho burundu ikibyimba gitera imisemburo myinshi yo gukuraho (GH). Niba umuganga ashoboye gukuraho igice kinini cya ikibyimba, ushobora kudakenera ubundi buvuzi. Ariko, niba igice kimwe cya kibyimba cyakuweho gusa, ushobora gukenera imiti cyangwa ubuvuzi bw'imirasire kugira ngo ugenzure ibimenyetso no kugabanya ikorwa rya GH.

Imiti ivura Acromegaly

Muganga wawe ashobora kuguha umuti umwe cyangwa imiti ivanze. Iyi miti ikora mu buryo butandukanye kugira ngo ivugurure urugero rw'imisemburo ikura mu mubiri wawe (GH) no kugabanya ibimenyetso. Hari ubwo umuti utangwa kugeza igihe ikibyimba kigabanutse, bityo umuganga ubaga akabasha kuyikuraho mu buryo bwizewe. Abandi bantu bashobora gukenera gufata imiti igihe kirekire kugira ngo bagenzure urugero rw'imisemburo ikura (GH) n'ibimenyetso byayo.

Ese acromegaly ishobora gukira burundu?

Acromegaly rimwe na rimwe ishobora gukira, ariko si buri gihe. Iyo ikibyimba cy’ubwonko gitera acromegaly gikuweho, igipimo cyo gukira kiba hafi 85% ku tubyimba duto . Ku tubyimba tunini, kiri hagati ya 40% na 50%.

Imiti ntishobora gukiza burundu acromegaly, ariko ishobora gutanga ubuvuzi bw'igihe kirekire kandi bwizewe .

Ese acromegaly ishobora kwirindwa?

Ikibabaje ni uko nta kintu na kimwe wakora kugira ngo wirinde acromegaly. Abahanga mu bya siyansi ntibaramenya neza icyatera ibibyimba byo mu bwonko bitera acromegaly. Ariko, bizera ko hari ibintu bimwe na bimwe bishobora kugira uruhare mu miterere y’umubiri .

Ni iki giteganyijwe ku ndwara ya acromegaly?

Uko ibi bizagenda biterwa n'uburemere bw'indwara n'uburyo ibimenyetso bigenzurwa neza hakoreshejwe imiti. Abantu benshi babona ko ibimenyetso bigabanuka cyane nyuma yo kuvurwa.

Iyo itavuwe, acromegaly ishobora guhindura cyane isura yawe n'imiterere y'amagufwa yawe. Ibi bimenyetso bishobora kugira ingaruka zikomeye ku kwiyubaha kwawe no ku mibereho yawe. Amatsinda y'ubufasha afasha bamwe mu bantu guhangana n'ibibazo bya acromegaly.

Acromegaly ishobora kandi gutera ibibazo ku buzima, nk'indwara z'umutima cyangwa diyabete yo mu bwoko bwa 2, bishobora kugabanya ubuzima no kugabanya igihe cyo kubaho. Kubwibyo, ni ngombwa kujya kwa muganga niba ufite ibimenyetso, kandi niba ubimenye, ugakurikiza gahunda yo kuvura neza.

Ni izihe ngorane zishobora kubaho iyo zitavuwe?

Iyo itavuwe, acromegaly ishobora gutera ingorane nka:

• Diyabete yo mu bwoko bwa 2
• Umuvuduko ukabije w'amaraso (Hypertension)
• Indwara z'umutima
• Indwara z'imitsi y'umutima (Cardiomyopathy)
• Rubagimpande
• Polyps zo mu mara - Izi zishobora kuba kanseri iyo zitavuwe.
• Kunanirwa kw'ingingo

Icyizere cy'ubuzima bw'umuntu ufite acromegaly ni ikihe?

Ibi biterwa n'uburemere bw'indwara ndetse niba hari izindi ndwara, akenshi ziterwa na acromegaly itavuwe.

Niba urugero rw'imisemburo yo gukura (GH) yawe rudagenzuwe neza kandi ufite izindi ndwara nk'indwara z'umutima na diyabete, igihe cyawe cyo kubaho gishobora kugabanukaho imyaka igera ku 10.

Ariko, niba ufite acromegaly, ukavurwa neza, kandi ufite urugero rusanzwe rw'imisemburo ikura (GH) na IGF-1, ushobora kubaho ubuzima busanzwe.

Ni ryari nkwiye kujya kwa muganga ku bijyanye na acromegaly?

Niba ufite ibimenyetso bya acromegaly, ni ngombwa cyane kuvugana na muganga.

Niba waranduye acromegaly, uzakenera kujya kwa muganga wawe buri gihe kugira ngo umenye neza ko ubuvuzi bwawe bukora neza.

Acromegaly ni indwara idasanzwe ariko ikomeye. Inkuru nziza ni uko ishobora kuvurwa no kubagwa, imiti, cyangwa imirasire. Niba wabonye ko amaboko, ibirenge, cyangwa isura yawe irimo kwiyongera, vugana na muganga wawe. Ashobora gukora ibizamini bike byoroshye kugira ngo arebe niba urugero rw'imisemburo yo gukura (GH) ari yo itera ibimenyetso byawe.

Amaherezo, ubutumwa bwo kujyana mu rugo

• Acromegaly ni indwara idakunze kugaragara ku bantu bakuru iterwa no kwiyongera kw'imisemburo itera gukura (GH).
• Ibimenyetso bishobora kuba birimo kubyimba amaguru n'amaboko no mu maso, ibyuya byinshi, no guhindura ijwi . Ibi bishobora kugaragara buhoro buhoro, bityo ushobora kutabibona.
• Impamvu nyamukuru ibitera ni ikibyimba, akenshi kitari kanseri, gikura mu gasabo k'ubwonko.
• Kumenya no kuvurwa hakiri kare bishobora gukumira ingorane nyinshi no kunoza ubuzima.
• Niba ufite ibi bimenyetso, ntutindiganye gushaka inama kwa muganga. Icyo ni cyo kintu cy'ubwenge kurusha ibindi byose.

Ibuka ko aya makuru ari ay'amakuru gusa. Ntiyagombye gukoreshwa nk'igisimbuzo cy'inama z'abaganga. Niba ufite ikibazo cy'ubuzima, nyamuneka gisha inama abaganga babishoboye.

Acromegaly , Imisemburo yo gukura, Ingirabuzimafatizo y'umuyoboro w'amaraso, Gigantism, IGF-1, Indwara y'imisemburo, Endocrine