Reka twige ku miti ya diyabete Canagliflozin na Metformin.

Ese urwaye diyabete, cyangwa Diyabete yo mu bwoko bwa 2? Cyangwa hari umuntu uzi ufite iyi ndwara? Ubwo muganga wawe ashobora kuba yaragundikiye imiti ibiri ivanze, ari yo Canagliflozin na Metformin, cyane cyane ikinini gisohora imiti mu buryo bwa "long-release pill". Izina ry'iki kimenyetso gishobora kuba Invokamet XR. Noneho, reka tuvuge byinshi kuri uyu muti uyu munsi, si byo se?

Ni iki koko kigenda gitya kuri uyu muti?

Muri make, uyu muti ukoreshwa mu kugenzura urugero rw'isukari mu maraso yawe (glucose mu maraso) . Iyo urwaye `Diabete yo mu bwoko bwa 2`, hari impinduka zimwe na zimwe mu buryo umubiri wacu ugenzura isukari. Uyu muti ukora ugabanya urugero rw'isukari kandi ukagufasha kugira ubuzima bwiza. Muri ibi, `Canagliflozin` ifasha umubiri gusohora isukari nyinshi mu nkari, mu gihe `Metformin` igabanya umusaruro w'isukari mu mwijima kandi ikongera ubushobozi bw'uturemangingo tw'umubiri bwo kumva insuline. Ariko ibuka ko uyu muti wonyine udahagije. Indyo nziza n'imyitozo ngororamubiri nabyo ni ingenzi cyane kuri ibi.

Ni ibihe bintu ugomba kubwira muganga wawe mbere yo gufata uyu muti?

Ibi ni ingenzi cyane. Niba ufite kimwe muri ibi bikurikira, ugomba kubibwira muganga wawe mbere yo gutangira uyu muti. Kuko, ni bwo muganga ashobora gufata icyemezo niba uyu muti ukubereye cyangwa utagukwiriye, cyangwa niba ingano yawo igomba guhinduka. Tekereza gusa, niba utabwiye muganga ibi bisobanuro, ushobora guhura n'ibibazo bitari ngombwa.

• Niba ufite `Anemia`
• Niba ufite indwara y'imitsi
• Niba warabuze amazi kubera kubura amazi
• Niba warigeze kugira `Diabete ketoacidosis (DKA)` (ubwiyongere bw'aside mu maraso bitewe na diyabete)
• Niba urya indyo irimo umunyu muke
• Niba urya bike bitewe n'uburwayi, kubagwa, indyo igabanya ubukana, cyangwa izindi mpamvu
• Niba ufite ibisebe ku birenge
• Niba ugiye kubagwa mu gihe kizaza
• Niba ufite indwara y'umutima
• Niba ufite cholesterol nyinshi (`cholesterol nyinshi`)
• Niba urugero rwa potasiyumu mu maraso ruri hejuru (`urugero rwinshi rwa potasiyumu mu maraso`)
• Niba warigeze gukurwaho ukuguru cyangwa igice cyabyo mbere (`Amateka yo gucibwa ingingo`)
• Niba ufite amateka yo kurwara pancreatitis cyangwa ibindi bibazo kuri pancreas yawe
• Niba ufite amateka yo kwandura indwara z'umusemburo mu gitsina cyangwa mu gitsina
• Niba ukunda kunywa inzoga buri gihe
• Iyo urwaye indwara mu ruhago, mu mpyiko, cyangwa mu nzira y'inkari
• Niba ufite indwara y'impyiko (uyu muti ntukwiriye niba imikorere y'impyiko iri munsi y'urwego runaka)
• Niba ufite indwara y'umwijima
• Niba ufite umuvuduko w'amaraso uri hasi (`Umuvuduko w'amaraso uri hasi`)
• Niba ufite ikibazo cy'imitsi
• Niba uri umuntu uri gukorerwa hemodialysis
• Niba ufite `Polycystic ovary syndrome (PCOS)` (indwara ituma udukoko twibasira intanga ngore)
• Niba ufite ikibazo cyo kunyara
• Niba ufite ubwandu bukomeye cyangwa igikomere gikomeye
• Niba urwaye diyabete yo mu bwoko bwa 1 (Uyu muti ni uw'abafite diyabete yo mu bwoko bwa 2)
• Niba uri umugabo utarakebwe
• Niba uhora uruka
• Niba ufite ikibazo cy'ubwivumbure kuri Canagliflozin, Metformin, indi miti, ibiryo, amarangi, cyangwa imiti irinda ubushyuhe
• Niba utwite cyangwa ugerageza gutwita
• Niba uri umubyeyi wonsa (`Ukonsa`)

Uru rutonde ntirugutere ubwoba. Ibi byose si ko bireba buri wese. Ariko niba hari ikintu kikureba, ni ngombwa ku bw'umutekano wawe kubibwira muganga wawe .

Uyu muti nkwiye kuwukoresha nte?

Noneho reka turebe uburyo bwo gukoresha uyu muti neza.

• Ugomba gufata iki ginini n'ikirahure cy'amazi .
• Ibi bigomba gufatwa n'ibiryo . Akenshi hamwe n'ifunguro rya mbere ry'umunsi. Cyangwa nk'uko muganga wawe yabigutegetse.
• Mirira ikinini cyose . Ntukagisye cyangwa ngo ukihekenye. Ibi biterwa nuko cyagenewe gukora igihe kirekire. Iyo ukimenetse, umuti uzahita winjira mu mubiri wawe ako kanya, bigatera kugabanuka gutunguranye kw'isukari mu maraso cyangwa ibindi bibazo.
• Fata umuti wanditswe na muganga, mu gihe cyagenwe, mu gipimo cyagenwe, nk'uko byavuzwe ku rupapuro rwanditswe na muganga.
• Ntukanywe ibirenze ibyo muganga yasabye, cyangwa ngo ubinywe kenshi.
• Ntugahagarike gufata imiti mu buryo butunguranye utabanje kugirwa inama na muganga. Kubikora bishobora gutuma isukari mu maraso yawe yiyongera mu buryo butunguranye.

Iyo ubonye uyu muti muri farumasi, uzahabwa agapapuro k'amakuru yihariye (`MedGuide`) hamwe na wo. Menya neza ko uwusoma witonze igihe cyose ubonye umuti wawe cyangwa ukawushyiramo 'rewyuzw'. Urimo amakuru menshi y'ingenzi kuri wewe.

Ese uyu muti ushobora guhabwa abana?

Ugomba kuvugana n'itsinda ry'abaganga ku bijyanye no guha abana uyu muti. Uyu muti akenshi uhabwa abantu bakuru. Iyo ukeneye abana, bisaba impamvu zidasanzwe n'ubuyobozi.

Bite se niba unywa inzoga nyinshi? (`Ingano irenze urugero`)

Niba ubona ko wafashe uyu muti urenze urugero, jya mu bitaro bikuru bikuru biri hafi yawe vuba, cyangwa uhamagare ikigo gishinzwe kugenzura uburozi (urugero: Ikigo cy'Igihugu gishinzwe amakuru ku burozi - 0112 686 143) . Ntugapfushe umwanya.

Icy'ingenzi: Uyu muti wanditswe kuri wewe gusa. Ntugasangire imiti yawe n'abandi, kabone n'iyo baba bafite ikibazo nk'icyawe. Kuko umuti ukorera umuntu umwe ushobora kudakorera undi.

Wakora iki niba wabuze dose y'umuti?

Oh, hari igihe ubura dose. Iyo bibaye bityo, fata vuba uko wibuka . Ariko, niba igihe cyo gufata dose ikurikira kigeze (urugero, mu masaha make), jya usimbuka dose yabuze hanyuma ufate dose ikurikira ku gihe cyagenwe. Ntukigere ufata dose ebyiri. Kubikora bishobora gutuma isukari mu maraso yawe igabanuka cyane.

Ni iyihe miti yindi ishobora kugira ingaruka kuri uyu muti?

Iki nacyo ni ingenzi cyane. Mu gihe ufata uyu muti wa 'Canagliflozin; Metformin', si byiza gufata indi miti. Nanone, ushobora kugira ingaruka ku yindi miti. Kubwibyo, ugomba kubwira muganga wawe imiti yose ufata (wanditswe na muganga, iyo uguze muri farumasi, imiti gakondo, vitamine, ndetse n'inyongeramusaruro ku mirire). Nanone, bwira muganga wawe niba unywa itabi, unywa inzoga, cyangwa unywa indi miti.

Imiti idakwiye gufatwa n'uyu muti:

• Hari ubwoko bumwe na bumwe bw'imiti "ivuguruzanya", itangwa mu mitsi mbere yo gupimwa nka X-rays, CT scans, na MRIs, ishobora kugira ingaruka ku mpyiko, kandi iyo ihujwe na "Metformin", byongera ibyago byo kurwara indwara ikomeye yitwa "Lactic Acidosis".
• `Dofetilide` (uyu ni umuti utangwa ku mikorere y'umutima idahwitse).

Indi miti ishobora kugira ingaruka kuri uyu muti:

(Uru rutonde rushobora kuba rutuzuye, bityo ni ngombwa kubwira muganga wawe ibyo ufata byose)

• 'Acetazolamide'
• Inzoga - Yongera ibyago byo kurwara aside ya lactic kandi ishobora no gutera isukari nke mu maraso.
• Imiti imwe n'imwe igabanya ubukana bwa virusi itera SIDA cyangwa Hepatite
• Imiti imwe n'imwe ivura umuvuduko w'amaraso, indwara z'umutima, n'indwara z'umutima (urugero: beta-blockers, zishobora guhisha ibimenyetso by'isukari nke mu maraso)
• 'Cimetidine'
• 'Dichlorphenamide'
• Digoxin (umuti w'umutima) - Igipimo cya Digoxin gishobora guhinduka iyo gifashwe na Canagliflozin.
• Imiti igabanya ubukana bw'amaraso (diuretics) - Yongera ibyago byo kubura amazi mu mubiri no kugabanuka k'umuvuduko w'amaraso.
• Imisemburo ya estrogene cyangwa progestin
• `Glycopyrrolate`
• `Isoniazid` (umuti uvura igituntu)
• `Lamotrigine`
• 'Lithiyumu'
• 'Memantine'
• 'Methazolamide'
• 'Metoclopramide'
• `Midodrine`
• 'Niacin'
• 'Phenobarbital'
• Phenothiazine (urugero: chlorpromazine, prochlorperazine, thioridazine)
• 'Fenytoin'
• 'Ranolazine'
• Rifampin (umuti ukoreshwa mu kuvura igituntu cyangwa izindi ndwara) - Ishobora kugabanya ubushobozi bwa Canagliflozin.
• 'Ritonavir'
• Imiti ya steroid (urugero: prednisone cyangwa cortisone) - ishobora kongera urugero rw'isukari mu maraso.
• Imiti itera imbaraga mu kugabanya ibiro, cyangwa gukomeza kuba maso
• Imiti ya tiroyide
• Topiramate
• 'Trospium'
• `Vandetanib`
• 'Zonisamide'

Tekereza gato, hari ibintu byinshi bishobora guhindura ingaruka z'uyu muti. Niyo mpamvu ari ngombwa cyane kumenyesha muganga wawe buri muti ufata .

Ni ibihe bintu ugomba kwitondera mu gihe ufata uyu muti?

Mu gihe ukoresha uyu muti, ugomba kwitondera ubuzima bwawe.

• Jyana na muganga wawe buri gihe ('isuzuma risanzwe') kugira ngo ukurikirane uko umerewe . Jyana ibizamini nko gukora kw'impyiko n'urugero rwa vitamine B12 nk'uko muganga wawe abivuga.
• Kubera ko uyu muti urimo 'Metformin', rimwe na rimwe aside mu maraso ishobora kwiyongera cyane (`Lactic Acidosis`) . Nubwo ibi bidakunze kubaho cyane, bishobora guteza akaga cyane iyo bibaye. Niba ugize ibimenyetso nko kugira isesemi, kuruka, kubabara mu gifu, umunaniro udasanzwe, kugorwa no guhumeka, guhumeka vuba, kumva ubukonje, cyangwa isereri, hagarika gufata uyu muti ako kanya hanyuma uhamagare muganga wawe cyangwa ujye kwa muganga . Niba bishoboka, reba kandi inkari zawe niba zirimo ketone ukoresheje 'ketone dipstick'.
• Canagliflozin ishobora kandi gutera indwara yitwa Diabetic Ketoacidosis (DKA) . Iyi ni indwara aho isukari mu maraso idakomeza kwiyongera cyane. Ibimenyetso birimo kugira inyota ikabije, kwihagarika kenshi, kuma mu kanwa, umunaniro, guhumeka nabi, guhumeka nabi, kubabara mu nda, isesemi no kuruka. Niba ubonye kimwe muri ibi bimenyetso, bwira muganga wawe vuba.
• Muganga wawe akunze gutegeka ikizamini cyitwa `HbA1C (A1C)` kugira ngo arebe uburyo isukari yawe yo mu maraso igenzurwa neza . Iki ni ikizamini cyoroshye cy'amaraso. Gishobora kwerekana uburyo isukari yawe yo mu maraso yagenzuwe neza mu gihe cy'amezi 2-3. Iki kizamini gikunze gukorwa buri mezi 3-6.
• Menya uburyo bwo gupima igipimo cy'isukari mu maraso yawe mu rugo . Nanone, menya ibimenyetso by'isukari nke mu maraso (hypoglycemia) n'isukari nyinshi mu maraso (hyperglycemia) n'uburyo bwo kubikemura .
• Buri gihe shyira ahantu hashobora kuboneka isukari (urugero: ibinini by'isukari, ibinini bya glucose, ikinyobwa kirimo isukari, umutobe w'imbuto) mu gihe uzagira ibimenyetso by'isukari nke mu maraso (ibyuya, guhinda umushyitsi, inzara ikabije, umutima utera cyane, isereri, urujijo). Ariko, niba utazi ubwenge cyangwa ufite igicuri , bwira abagize umuryango wawe ko bashobora kurohama nibagerageza kuguha ibiryo cyangwa icyo kunywa. Ibi nibibaho , ugomba kwihutira gushaka abaganga .
• Uyu muti ushobora kugabanya urugero rwa aside folike na vitamine B12, cyane cyane iyo ukoresheje metformin. Kubwibyo, menya neza ko urya vitamine zihagije mu gihe ufata uyu muti. Muganga wawe ashobora kukwandikira inyongera ya vitamine nibiba ngombwa.
• Irinde umwuma . Nywa amazi menshi, cyane cyane mu gihe cy'ubushyuhe, mu gihe ukora imyitozo ngororamubiri, cyangwa niba ubabara mu nda.
• Wite cyane ku birenge byawe . Suzuma ibirenge byawe buri munsi, kuko hari ibyago bike byo kwandura cyangwa gucibwa amaguru yo hasi mu gihe ufata uyu muti (cyane cyane Canagliflozin). Niba rero ufite ibikomere, imikaya, gutukura, cyangwa kubyimba ibirenge byawe, bimenyeshe muganga wawe vuba.

Ni izihe ngaruka mbi zishobora guterwa n'uyu muti?

Nk’uko bimeze ku muti uwo ari wo wose, uyu ushobora gutera ingaruka zimwe na zimwe. Ariko si buri wese uzibona. Zimwe zirakomeye kandi ugomba kubimenyesha muganga wawe ako kanya. Izindi akenshi ntabwo ziba zikomeye, ariko niba zikomeje, ni byiza kubimenyesha muganga wawe .

Ingaruka mbi ugomba guhita ubibwira muganga wawe

• Indwara zo kugira ubwivumbure : uduheri ku ruhu, kuribwa, uduheri (uduheri dutukura ku ruhu), kubyimba mu maso, ku minwa, ku rurimi, cyangwa mu muhogo (bishobora gutera kugorwa no guhumeka).
• Kubura amazi mu mubiri : Inyota nyinshi, umunwa wumye, isereri, kuribwa umutwe, inkari z'umuhondo wijimye cyangwa umukara, no kugabanuka k'inkari.
• Ketoacidosis ya diyabete (DKA) : Inyota cyangwa inkari nyinshi, umunwa wumye, umunaniro ukabije, impumuro y'umusaruro, guhumeka nabi, kubabara mu gifu, isesemi no kuruka.
• Indwara y'umusemburo mu gitsina : (mu gitsina ku bagore, mu gitsina ku bagabo) gutukura, kubyimba, kubabara cyangwa kwishima, impumuro mbi, n'amatembabuzi y'umweru menshi cyangwa ashyushye.
• Ubwiyongere bwa aside lactic mu maraso (`Lactic Acidosis`) : Kubabara imitsi cyangwa kuribwa mu nda, kubabara mu gifu, guhumeka bigoranye, guhumeka vuba, kubabara no kunanirwa muri rusange, isereri, gukonja.
• Kwandura indwara zikikije imyanya ndangagitsina cyangwa mu gace gatera ikibuno (`Fournier's gangrene`) : gutukura, kubyimba, gukomera, cyangwa ububabare, rimwe na rimwe hamwe n'umuriro. Iyi ni indwara ikomeye cyane, ishobora gushyira ubuzima mu kaga, bityo rero bwira muganga wawe vuba niba ubonye kimwe muri ibi bimenyetso.
• Urugero rwa Vitamine B12 ruto : Ububabare, kugira ibinya, cyangwa kubura ibyiyumvo mu ngingo, intege nke z'imitsi, isereri, kugorwa no kwita ku ngingo, urujijo, kubabara ururimi, guhindura ibara ry'uruhu.
• Ububabare bushya cyangwa gukomera kw'ukuguru cyangwa ukuguru, ibara ry'uruhu, ibisebe cyangwa ibisebe, cyangwa ubwandu.Ibi nabyo ni ibintu bigomba kwitabwaho vuba.
• Kwandura indwara zo mu nkari (UTI) : Kumva ubushyuhe iyo uri kunyara, kunyara kenshi, inkari zirimo amaraso cyangwa ibicu, kubabara mu mugongo wo hasi cyangwa mu kibuno, umuriro.
• Kuvunika kw'amagufwa : Ubushakashatsi bumwe bwagaragaje ko ibyago byo kuvunika amagufwa byiyongera gato ku bantu bafata Canagliflozin. Bityo rero, witondere kugwa.

Ingaruka mbi akenshi zidasaba inama kwa muganga, ariko niba zikomeje, ugomba kubimenyesha muganga wawe.

• Impiswi
• Gazi
• Umutwe
• Isesemi
• Ububabare bwo mu gifu
• Kuruka
• Kongera inshuro zo kunyara
• Inyota ikabije

Uru rutonde rushobora kuba rudafite ingaruka mbi zose. Niba ubonye ikintu kidasanzwe, vugana na muganga wawe. Ushobora kandi gutanga raporo ku bisubizo bya FDA (Ikigo gishinzwe ibiribwa n'imiti) kuri 1-800-FDA-1088.

Ukwiye kubika gute imiti yawe?

Ni ingenzi cyane kandi kubika imiti yawe neza.

• Bika ahantu abana n'amatungo batagera.
• Bika ahantu hari ubushyuhe bwinshi mu cyumba (hagati ya dogere selisiyusi 15 na 30, hagati ya dogere selisiyusi 59 na 86). Birinde ubushuhe bwinshi n'izuba ryinshi. Ntukabibike ahantu hari ubushuhe bwinshi, nko mu bwiherero.
• Ntugakoreshe imiti yarengeje igihe. Ijugunye.

Ni gute wajugunya imiti itarakoreshejwe n'iyarengeje igihe?

• Niba bishoboka, tanga uyu muti muri gahunda yo gufata imiti. Ushobora kumenya amakuru yerekeye ahantu nk'aho muri farumasi yawe cyangwa ku buyobozi bw'ubuzima bwo mu gace utuyemo.
• Niba atari byo, reba ku gapapuro k'umuti kugira ngo urebe niba ukwiye kujugunywa mu myanda cyangwa kujugunywa mu musarani. Niba utabizi neza, baza muganga wawe cyangwa umufarumasiye.
• Niba ushobora kuyijugunya mu myanda (ibikunze kubaho), kuraho umuti mu gikoresho, uwuvange n'ikintu utazarya, nk'ikawa yakoreshejwe, itaka, cyangwa umwanda w'injangwe, hanyuma uwushyire mu gikapu cyangwa mu gikoresho gifunga hanyuma uwujugunye mu myanda. Ibi ni ukugira ngo wirinde ko undi muntu abona umuti no kuwukoresha.

Ubutumwa bwo kujyana mu rugo

Twavuze byinshi ku miti ya diyabete `Canagliflozin` na `Metformin`. Muri make:

• Uyu ni umuti w'ingenzi ku ndwara ya Diyabete yo mu bwoko bwa 2 ugenzura isukari mu maraso .
• Ibisubizo byiza bigerwaho iyo ibi bihujwe n'imirire n'imyitozo ngororamubiri.
• Menya neza ko wabwiye muganga wawe izindi ndwara zose ufite hamwe n'indi miti yose ufata.
• Nkuko muganga yabivuze,Fata igipimo cyagenwe, ku gihe cyagenwe, hamwe n'ibiryo . Mirira ikinini cyose.
• Menya ibimenyetso by'isukari nke mu maraso (hypoglycemia) kandi ubike isukari hafi igihe uyikeneye.
• Niba ubonye ibimenyetso bidasanzwe (cyane cyane ibimenyetso bishobora kuba bya `DKA` cyangwa `Lactic Acidosis`, indwara zo mu myanya ndangagitsina (ibyago byo kurwara `Fournier's gangrene`), ibisebe byo ku maguru, ibimenyetso byo kubura amazi mu mubiri), bwira muganga wawe ako kanya.
• Komeza kuvugana na muganga wawe kandi umuganirize ku kibazo cyawe. Ntutinye kubaza ibibazo.

Wibuke ko uyu muti ari umuti ufasha mu kugenzura diyabete yawe gusa. Ubuzima bwawe bushingiye gusa ku mibereho yawe, imirire, no gukurikiza amabwiriza ya muganga wawe. Uyu muti ntuvura diyabete, ahubwo ufasha gusa kuyigenzura.

Niba ufite ibindi bibazo, ntugatinye kubaza muganga wawe, umufarumasiye, cyangwa undi muvuzi. Barahari kugira ngo bagufashe.

Canagliflozin , Metformin, Invokamet XR, Diyabete yo mu bwoko bwa 2, Diyabete, Isukari yo mu maraso, Imiti ya Diyabete, Ingaruka mbi