Ese umwongo wawe w'amagufwa ntukora neza? Reka tuvuge ku bijyanye no kugabanya myelosuppression!

Ese wumva utameze neza, uhora urwara, cyangwa uva amaraso nubwo waba ufite igisebe gito, waba uri kuvurwa kanseri cyangwa indi ndwara? Inyuma y'ibi bintu, hashobora kubaho myelosuppression , indwara ituma umwongo udakora neza . Ntugahangayike, reka tubiganireho mu buryo bworoshye.

Kugabanya imitsi mu magufwa ni iki? Mu by'ukuri, ese ni ukugabanuka k'umusemburo w'amagufwa?

Mu magambo make, yego! Umwotsi w'amagufwa ni uturemangingo tworoshye kandi dusa n'udusimba tuba mu magufwa yawe. Tekereza nk'uruganda rw'umubiri wacu rukora amaraso . Uru ruganda rukora za miliyari z'uturemangingo dutukura tw'amaraso, uturemangingo twera tw'amaraso, na plaquettes, ari ingenzi kugira ngo tubeho, kandi tukongera mu maraso yacu. Buri bwoko bw'uturemangingo bufite akazi gatandukanye ku mubiri wacu. Umwotsi w'amagufwa wongera cyangwa ukagabanya uyu musaruro bitewe n'ibyo umubiri wacu ukeneye.

Ubu, mu ndwara yitwa myelosuppression , akazi k'uru ruganda rw'umusemburo w'amagufwa karahungabanye kubera impamvu runaka. Hanyuma, uturemangingo tw'amaraso na plaquettes ntibishobora gukorwa neza. Impamvu nyamukuru ibi ni ukuvura kanseri hakoreshejwe imiti . Ariko, ubwoko bumwe na bumwe bwa kanseri y'amaraso na virusi zimwe na zimwe na byo bishobora gutuma umwomburo w'amagufwa unanirwa.

Ni ibihe bimenyetso by'indwara yo kugabanya myelosuppression?

Ibimenyetso bishobora gutandukana bitewe n'umuntu ku wundi, bitewe nuko umwongo wawe w'amagufwa ukora uturemangingo dutukura tw'amaraso, uturemangingo twera tw'amaraso, cyangwa uduce duto tw'amaraso.

Iyo uturemangingo dutukura tw'amaraso tugabanuka - Anemia

Uturemangingo dutukura dutwara umwuka wa ogisijeni mu mubiri wawe wose. Iyo tudafite uturemangingo duhagije , amaraso agabanuka. Ibimenyetso bishobora kuba:

• Umunaniro
• Kubura umwuka / kubura umwuka
• Kuzungera
• Umutima utera vuba cyangwa utari mu buryo busanzwe / arrhythmia
• Kumva ijwi ricurama mu matwi, rimwe na rimwe riherekejwe n'ijwi ryo "gukubita" n'umutima (Pulsatile tinnitus)
• Umutwe
• Ubusa bw'ibara ry'uruhu
• Kubabara mu gatuza

Neutropenia - kugabanuka k'uturemangingo tw'amaraso twera (cyane cyane utunyangingo tw'amaraso)

Uturemangingo tw’amaraso tureshya udukoko twinjira mu mibiri yacu kandi tukaturinda kwandura . Ubwoko bumwe bw’uturemangingo tw’amaraso bwera bwitwa neutrophils . Iyo umwongo w’amagufwa utanga neutrophils nke bitewe no kugabanuka kwa myelosuppression, iyo ndwara yitwa neutropenia . Neutropenia nta bimenyetso byihariye igira, ariko kubera ibiKwandura indwara kenshi bishobora kubaho, kandi ni bwo ibimenyetso bigaragara.

• Umuriro (rimwe na rimwe witwa febrile neutropenia )
• Umunaniro
• Kubabara mu muhogo/ubwandu (Kubabara mu muhogo/pharyngitis)
• Utudomo tw'imitsi tubyimbye
• Ibisebe mu kanwa cyangwa hafi y'ikibuno
• Impiswi
• Kubabara igihe uri kunyara, kumva ukeneye kunyara vuba, kunyara kenshi

Iyo platelets zigabanutse - Thrombocytopenia

Platelets zifasha mu kugenzura kuva amaraso . Iyo ibi bipimo bigabanutse, habaho indwara yitwa thrombocytopenia . Ibi bishobora gutera:

• Kuva amaraso igihe kirekire, ndetse no mu gikomere gito, cyangwa kugorwa no guhagarika kuva amaraso mu mazuru.
• Ibisebe bigaragara vuba kurusha uko bisanzwe.
• Kugaragara kw'utudomo duto dutukura (nk'uduheri) ku maguru yo hasi - ibi byitwa petechiae .
• Uduheri tw'umutuku, umuhengeri, cyangwa umukara ku ruhu - ibi byitwa purpura .

Iyo ubwoko bwose bw'uturemangingo tw'amaraso bugabanutse - Pancytopenia

Hari igihe, utwo tunyangingo tw’amaraso uko ari dutatu—utunyangingo dutukura, utwatsi tw’amaraso twera, n’utunyangingo twa plaquettes—tushobora kuba duke icyarimwe . Iyi ndwara yitwa pancytopenia . Kimwe na neutropenia, iyi si indwara ubwayo, ariko ishobora kuba ikimenyetso cy’indwara runaka.

Kuki habaho myelosuppression? Ni izihe mpamvu?

Nkuko twabivuze mbere, imiti ivura indwara ya chimiotherapie ni yo ikunze kugaragara cyane . Ariko hari n'izindi mpamvu.

Kuvura hakoreshejwe imiti igabanya ubukana bw'umubiri, no kugabanya myelosuppression

Ubwoko butandukanye bw'imiti ya chimiotherapie bushobora gutera ibi. Imwe muri iyi ikunze kugaragara ni iyi:

• Fluorouracil
• Oxaliplatin
• Irinotecan
• Capecitabine

Byongeye kandi, uburyo bwo kuvura uturemangingo twa CAR T, ubwoko bwa immunotherapy , bushobora kandi kwangiza imikorere y'umusemburo w'amagufwa no kugabanya umusaruro w'uturemangingo tw'amaraso na platelets.

Kanseri y'amaraso n'igabanuka ry'imitsi

Kanseri zimwe na zimwe zo mu maraso zishobora no kubangamira ikorwa ry’uturemangingo tw’amaraso risanzwe. Urugero, muri kanseri nka kanseri ya kanseri y’amaraso, kanseri ya kanseri ya kanseri , uturemangingo twa kanseri tudasanzwe dukura cyane mu musokoro w’amagufwa kandi tugahagarika ikorwa ry’uturemangingo tw’amaraso n’udupira tw’amaraso tuzima.

Virusi no kugabanya myelosuppression

Hari ubwandu bwa virusi bushobora kandi kubangamira inzira yo gukora amaraso mu musemburo w'amagufwa. Tekereza ko iyo virusi yinjiye mu mubiri, ubwirinzi bw'umubiri wacu, ni ukuvuga uturemangingo tw'amaraso twera, barwanya virusi. Muri uru rugamba, umusemburo w'amagufwa ushobora gukora uturemangingo duto dutukura n'udukoko duto. Ubushakashatsi bumwe bwerekana ko hari virusi zanduza uturemangingo dukora amaraso mu musemburo w'amagufwa, bikagabanya umubare w'uturemangingo tw'amaraso. Hari virusi zagaragaye ko zifitanye isano n'iki kibazo cyo kugabanya amaraso mu musemburo w'amagufwa ni izi:

• Virusi ya Epstein-Barr (EBV)
• Virusi ya Hepatite C
• Virusi ya Parvovirus B19
• Virusi ya Cytomegalovirus (CMV)
• Virusi itera inkoko (Chickenpox / varicella zoster)
• Virusi itera SIDA (HIV)
• Umuriro wa Dengue

Ese myelosuppression ishobora guteza ingorane zikomeye?

Yego, hari igihe ibi bishobora gutera ingorane zishobora gushyira ubuzima mu kaga . Urugero, kugabanuka gutunguranye kw'uturemangingo dutukura tw'amaraso (amaraso adafite amaraso menshi) cyangwa kugabanuka kw'uturemangingo (kuva amaraso mu buryo budasubirwaho) .

Icy'ingenzi: Niba ubonye kimwe muri ibi bimenyetso, cyane cyane niba uri kuvurwa kanseri, ni ngombwa cyane gushaka inama kwa muganga byihutirwa.

Ni gute abaganga basuzuma neza iyi ndwara?

Ibi ahanini bipimwa binyuze mu gupima amaraso . Ibi bipimo by'amaraso bireba niba umwongo w'amagufwa yawe urimo gukora uturemangingo tw'amaraso n'udupira tw'amaraso mu buryo busanzwe.

Ibipimo by'amaraso nk'ibi bishobora gukorwa:

• Umubare w'amaraso yuzuye (CBC)
• Ikizamini cya MCV (Ingano y'ingano y'umubiri / ikizamini cya MCV)
• Ikizamini cya RDW (Ubugari bw'ikwirakwizwa ry'uturemangingo dutukura / Ikizamini cya RDW)
• Umubare wa reticulocyte
• Gupima amaraso yo mu mpande
• Ikizamini cya MPV (ingano y'amaraso akoreshwa mu gupima platelet / ikizamini cya MPV)

Ni ubuhe buryo bwo kuvura indwara yo kugabanya myelosuppression?

Abaganga bavura ibi bakoresheje ubu buryo:

• Niba impamvu yo kugabanya myelosuppression ari chemotherapy, ingano ya chemotherapy igomba kugabanuka cyangwa igahagarikwa by'agateganyo .
• Guterwa amaraso kugira ngo hongerwe urugero rw'uturemangingo dutukura tw'amaraso n'udupira tw'amaraso.
• Kuguha imiti ifasha umwongo wawe gukora uturemangingo twinshi tw'amaraso na plaquettes.

Ese iki kibazo gishobora kwirindwa kubaho?

Kugabanya imitsi y'amaraso (myelosuppression) akenshi bibaho nk'ingaruka mbi zo kuvura kanseri. Kubwibyo, abaganga bahora bareba izi ngaruka mbi mu gihe cyo kuvura kanseri. Bazasuzuma amaraso yawe buri gihe kandi bagire impinduka ku gahunda yawe yo kuvura nibiba ngombwa.

Ni iki nakwitega mu gihe mfite myelosuppression?

Abantu benshi barwara iyi ndwara kuko bahabwa imiti igabanya ubukana bw'indwara ya chimiotherapie. Niba ari uko bimeze, muganga wawe azakurikirana neza uburyo imiti igabanya ubukana bw'indwara ya chimiotherapie ikora ku musokoro w'amagufwa yawe. Ushobora gukenera gufata ikiruhuko gito cyo kuvurwa na kanseri kugira ngo umwokoro w'amagufwa yawe wongere umubare w'uturemangingo tw'amaraso.

Nitwara nte?

Kugabanya myelosuppression bishobora kongera ibyago byo kwandura indwara no kuva amaraso . Ushobora gukora ibi kugira ngo ugabanye ibi byago:

• Shaka inkingo zo kwirinda virusi zisanzwe.
• Gukoresha imyitozo ngororamubiri myiza , nko gukaraba intoki kenshi no kwirinda kwegera abarwayi.
• Irinde ibintu bishobora gutuma ukomereka cyangwa ugakomereka . Urugero, witondere iyo ukoresha intwaro zityaye.

Ni ibihe bibazo ngomba kubaza muganga wanjye?

Ushobora kubaza muganga ibibazo nk'ibi:

• Kuki mfite iyi ndwara yo kugabanya myelosuppression?
• Iyi ndwara igira ingaruka zite ku mubiri wanjye?
• Ni ubuhe buryo bwo kuvura mfite?
• Ese kuvurwa bizakiza burundu myelosuppression yanjye?

Incamake: Icyo ugomba kwibuka (Ubutumwa bwo kujyana mu rugo)

Umwongo wo mu igufwa ryawe ni igice cy'ingenzi cy'umubiri wawe. Uturemangingo dutukura dutwara ogisijeni, uturemangingo tw'amaraso twera turwanya indwara, uduce duto dufasha amaraso yawe kubumba - byose bikorerwa aho. Kugabanya myelosuppression ni igihe umwongo wo mu igufwa ryawe uhagarara gukora kubera impamvu runaka. Impamvu ikunze kugaragara ni imiti ivura kanseri, ariko ishobora no guterwa na kanseri zimwe na zimwe z'amaraso na virusi. Ntugahangayike. Abaganga bazashaka impamvu kandi bayivure uko bikwiye. Icy'ingenzi ni ukugana abaganga niba ufite ibimenyetso bidasanzwe kandi ugakurikiza inama zabo witonze. Ntabwo uri wenyine, kandi hari abaganga bashobora kugufasha muri uru rugendo.

Kugabanya imitsi , Kugabanya imitsi y'amagufwa, Kugabanya imitsi y'amagufwa, Uturemangingo dutukura tw'amaraso, Uturemangingo tw'umweru tw'amaraso, Uduce duto tw'amaraso, Uduce duto tw'imitsi, Kanseri, Kubura amaraso, Neutropenia, Thrombocytopenia, Ubwandu