Ese nawe ufite impumuro nk'iy'amafi? Reka twige kuri Trimethylaminuria (TMAU)!

Hari igihe mu buzima bwacu haba ibintu bidasanzwe, si byo se? Ese wigeze wumva ikibazo aho umubiri w'umuntu, ibyuya, umwuka we, cyangwa inkari ze binuka nk'amafi yaboze? Bisa n'ibitangaje, si byo se? Ariko, hari ikibazo nk'icyo koko. Iyi ni yo ndwara tugiye kuvugaho uyu munsi, Trimethylaminuria, cyangwa `(TMAU)` mu magambo ahinnye. Hari n'abantu bayita ``Fish Odor Syndrome``.

Trimethylaminuria (TMAU) ni iki?

Mu magambo make, trimethylaminuria (TMAU) ni indwara iterwa n’imikorere y’umubiri . Noneho ushobora kuba wibaza icyo indwara iterwa n’imikorere y’umubiri ari cyo. Mu mibiri yacu, inzira z’ibinyabutabire, cyangwa inzira z’imikorere y’umubiri , zibaho kugira ngo ibiryo turya bihinduke ingufu no gutuma ibintu umubiri wacu ukeneye biba ibyo ukenera. Enzymes mu mibiri yacu zifasha izi nzira kubaho neza. Rero, muri iki kibazo cyitwa trimethylaminuria, bitewe n’impinduka mu mikorere y’umusemburo runaka, zimwe mu misemburo ikorerwa mu mubiri ntishobora kwangirika neza. Niyo mpamvu iyo mpumuro mbi nk’iy’amafi ituruka ku byuya, umwuka, amacandwe, n’inkari.

Ushobora kuba warumvise abaganga bita iyi ndwara `(TMAU)` cyangwa `(Impumuro mbi y'amafi)`. Nta muti wuzuye uhari kugeza ubu . Ariko, ntugahangayike. Ushobora kugabanya ibi bimenyetso ku rugero runini uhindura ibyo urya n'ibyo unywa, ukoresha amasabune n'amavuta yo kwisiga amwe na amwe, kandi ugacunga imihangayiko yawe.

Ni ubuhe bwoko bw'ingenzi bwa `(TMAU)`?

Hari ubwoko bubiri bw'ingenzi bwa trimethylaminuria:

1. Trimethylaminuria y'ibanze : Iyi ni ubwoko bw'indwara ivukanwa . Ibi bivuze ko iyi ndwara iterwa n'impinduka zimwe na zimwe (`(mutations genetic)`) mu turemangingo (`(Genes)`) dukomoka kuri nyina na se.

2. Trimethylaminuria ya kabiri : Ibi bibaho mu myaka yashize . Iyi mpumuro nk'iy'amafi ishobora guterwa n'indwara zimwe na zimwe cyangwa inyongeramusaruro mu mirire.

Iyi ndwara ikunze kugaragara gute?

Mu by’ukuri, TMAU ni indwara idakunze kugaragara . Hari ubushakashatsi bwerekana ko ifata umuntu umwe gusa ku bantu 200.000 kugeza kuri miliyoni imwe ku isi. Ariko kandi, bivugwa ko abagore bafite amahirwe make yo kuyirwara kurusha abagabo.

Ariko, abashakashatsi bamwe bemeza ko hashobora kuba hari abantu benshi bafite `(TMAU)` muri sosiyete kurusha uko iyi mibare ibigaragaza. Kubera ko abantu benshi batekereza ko iki ari ikibazo cy’isuku yabo bwite . Kubwibyo, ntibabibwira umuntu uwo ari we wese cyangwa ngo bajye kwa muganga kubera isoni. Bityo, ntibahabwa isuzuma (`(Isuzuma)`).

Ni ibihe bimenyetso bya trimethylaminuria?

Ikimenyetso nyamukuru kandi kigaragara cyane ni impumuro y'amafi ituruka mu mubiri, mu mwuka no mu byuya . Iyi mpumuro rimwe na rimwe ishobora kuba mbi cyane ku buryo ishobora gutera isesemi. Kuri bamwe, ishobora no guherekezwa n'impumuro mbi (`(Halitosis)`) n'impumuro ikomeye ituruka mu nkari.

Hari igihe umuntu ufite `(TMAU)` yumva impumuro nk'iyi cyane iyo abira ibyuya cyangwa iyo afite stress. Ariko, kuri bamwe, iyi mpumuro iba ikomeye cyane ku buryo nubwo bajya mu cyumba batuyemo, bahagaze imbere y'aho bagurishiriza mu iduka, cyangwa bicaye ku ruhande rumwe rwa bisi cyangwa gari ya moshi, abandi baracyashobora kuyihumura. Tekereza ukuntu bigoye.

Ni izihe mpamvu za `(TMAU)`?

Trimethylaminuria ibaho iyo imikorere ya enzyme yitwa `(FMO3)` mu mubiri wacu ihungabanye. `(FMO3)` isobanura monooxygenase 3 irimo Flavin. Akamaro k'ingenzi k'iyi enzyme ni ukugenzura chemical yitwa `( Trimethylamine )` ikorerwa mu mubiri wacu. Iyi trimethylamine niyo itera iyo mpumuro y'amafi. Iyi trimethylamine ikorwa iyo ibiryo bimwe na bimwe turya, urugero nk'amafi, ibishyimbo, n'amagi, bishongeshejwe.

Ibisanzwe bibaho ni ibi: Iyo trimethylamine yibumbiye mu mibiri yacu, enzyme `(FMO3)` iraza ikayica, ikayihinduramo chemical idafite impumuro. Hanyuma, nubwo iva mu gifu cyacu ikajya mu maraso yacu, ntabwo impumuro irahumura.

Ariko se, bigenda bite iyo enzyme ya `(FMO3)` idakora neza? Iyo trimethylamine ihumura irakomeza kwiyongera mu mibiri yacu. Iyo imaze kwiyongera, amaherezo isohoka mu byuya, mu mwuka, mu macandwe no mu nkari, maze iyo mpumuro nk'iy'amafi ikavamo. Urabyumva?

Abantu bafite trimethylaminuria y’ibanze (`(Primary TMAU)`) barwara iyi ndwara kuko bakura kopi zidasanzwe z’uturemangingo dukora enzyme ya `(FMO3)` (`(Abnormal FMO3 genes)`) kuri nyina na se.

Mu gihe cy’igabanuka rya trimethylaminuria (`(Secondary TMAU)`), enzyme yawe ya `(FMO3)` ntabwo ibasha gusenya trimethylamine kubera indi mpamvu. Ibi bishobora guterwa na:

• Niba ufite ikibazo cy’uburwayi, nko kunanirwa k’umwijima cyangwa indwara ya hepatitis iterwa na virusi , bishobora kubangamira imikorere y’iyi enzyme no kuyibuza gusenya trimethylamine.
• Niba mikorobe zo mu mara yawe zidakora neza, bivuze ko hari ubusumbane hagati ya bagiteri nziza n'izibi mu mara yawe, trimethylamine nyinshi ishobora kwirundanya. Icyo gihe enzyme (FMO3) ntishobora gukuraho iyo mpumuro yose.
• Iyo ufashe inyongeramusaruro zirimo choline cyangwa carnitine , izi ntungamubiri zigira uruhare mu ikorwa rya trimethylamine.

Ni izihe ngorane ziterwa n'iyi ndwara?

Uburyo indwara yitwa trimethylaminuria igira ingaruka ku mibereho yawe(`(Ubuzima bwiza)`) bushobora kwangiza cyane. Ubushakashatsi bwerekana ko abantu bafite iyi ndwara bakunze kwirinda imibanire, akazi, n'ibikorwa byo gusabana kuko batinya ko abandi bazabona impumuro mbi. Kubera iyo mpamvu, abantu bafite iyi ndwara bashobora kugira ibibazo bitandukanye by'ubuzima bwo mu mutwe. Urugero:

• Guhangayika
• Ihungabana
• Guhangayika no gutinya bidafite ishingiro (`(Paranoia)`)

Nubwo ari gake cyane, bamwe mu bantu barwaye TMAU bavuzweho kugira ibitekerezo byo kwiyahura (`(imyitwarire yo kwiyahura)`). Ibi bigaragaza uburyo ingaruka z'iyi ndwara zishobora kuba zikomeye mu mutwe.

Trimethylaminuria ipimwa ite?

Abaganga bapima TMAU bapima ingano ya trimethylamine mu nkari zawe. Ibi bikunze gukorwa binyuze mu isuzuma ry'inkari . Byongeye kandi, muganga wawe ashobora kukugira inama yo gupima imiterere y'uturemangingo kugira ngo amenye niba ufite imiterere y'ibanze (ni ukuvuga iy'amavuko) cyangwa iy'inyongera (ni ukuvuga iy'ubusanzwe).

Ni ubuhe buryo bwo kuvura trimethylaminuria?

Muganga wawe ashobora kukugira inama y'ibintu bitandukanye bifasha kugabanya ibimenyetso bya TMAU.

• Indyo: Ni byiza kureka ibiryo bimwe na bimwe byongera umusaruro w'ibinyabutabire mu mubiri bitera iyo ndwara (TMAU).
• Amasabune n'amavuta yihariye: Ni byiza gukoresha amasabune n'amavuta yihariye afasha kugabanya impumuro y'amafi mu ruhu.
• Imiti: Hari igihe imiti ishobora no gutangwa.
• Ubufasha mu buzima bwo mu mutwe: Ushobora kandi kugirwa inama yo gushaka inama z'imitekerereze kugira ngo bigufashe guhangana n'umuhangayiko uterwa n'iyi ndwara.

Ni ubuhe bwoko bw'ibiribwa bukwiye kureka gukoreshwa?

Niba ufite trimethylaminuria, abaganga bakunze kukubwira kugabanya cyangwa kwirinda burundu ibi bikurikira:

• Amafi n'ibindi bimera byo mu nyanja (cyane cyane amafi yo mu mazi y'umunyu)
• Amagi (cyane cyane umuhondo w'igi)
• Umwijima n'izindi ngingo z'imbere mu nyamaswa
• Ibinyamisogwe nka soya, ubunyobwa n'inkeri
• Imboga zo mu bwoko bwa Cruciferous nka amashu, broccoli, cauliflower, na Brussels sprouts
• Ubunyobwa
• Amata n'ibikomoka ku mata (kuri bamwe)
• Ibyokurya n'intungamubiri bikungahaye kuri choline na L-carnitine

Icy'ingenzi: Si buri wese ugomba kureka ibyo biribwa byose. Ni byiza kuvugana na muganga cyangwa inzobere mu mirire kugira ngo bamenye ibiryo bikubereye.

Ni iyihe miti itangwa kuri `(TMAU)`?

Muganga wawe ashobora kukwandikira imiti nk'iyi kugira ngo agabanye ibimenyetso bya TMAU:

• Antibiyotike na probiotics : Iyi miti ifasha kugabanya umubare wa bagiteri mu mara yawe, bityo ikagabanya ikorwa rya trimethylamine.
• Amakara akoreshwa : Ibi bimeze nk'ikirungo. Bikurura trimethylamine mu mubiri kandi bigafasha gusohoka mu mwanda.
• Imiti igabanya kwiheba n'imiti igabanya guhangayika : Iyi miti itangwa kugira ngo ivure ibibazo by'ubuzima bwo mu mutwe bamwe mu barwayi ba TMAU bahura nabyo.

Muganga wawe ashobora kandi kukwohereza mu buvuzi bw'indwara zo mu mutwe . Kuganira n'umuganga w'imitekerereze cyangwa umujyanama ni ingenzi cyane cyane niba uhanganye n'ibibazo byo kwiyubaha no kugaragara neza mu mubiri wawe. Ubuvuzi bw'imitsi bushobora kugufasha kumenya uburyo bwo guhangana n'ikibazo cyawe no gucunga imihangayiko.

Ni iki umuntu urwaye trimethylaminuria ashobora kwitega?

Trimethylaminuria ni indwara idakira . Ibi bivuze ko idashobora gukira burundu cyangwa ngo yongere gukira ubwayo. Ariko, nk'uko byavuzwe mbere, hari uburyo bwo kuvura n'ibintu ushobora gukora kugira ngo ugabanye ibimenyetso bya TMAU kandi ugabanye ingaruka iyo ndwara igira ku buzima bwawe.

Nitwara nte?

Kwiyitaho ni ingenzi cyane mu gihe ubana na TMAU. Dore bimwe mu bintu ugomba kuzirikana:

• Isuku ku mubiri : Gukoresha amasabune n'amavuta yo kwisiga afite agaciro ka `(pH)` gake bishobora kugufasha kugabanya impumuro mbi y'umubiri wawe. Baza muganga wawe agaciro ka `(pH)` kakubereye n'ibicuruzwa byiza.
• Witondere ibyo urya : Ibiryo byinshi bishobora gutuma trimethylaminuria irushaho kuba mbi. Vugana n'inzobere mu mirire kugira ngo bagufashe gutegura amafunguro yawe n'amahitamo y'ibyo kurya kugira ngo ubone intungamubiri ukeneye.
• Gucunga stress : Kongera stress bishobora kongera ibimenyetso bya TMAU. Bityo rero, baza muganga wawe uburyo bwo kugabanya stress yawe. (urugero: gutekereza cyane, yoga, imyitozo ngororamubiri yo guhumeka)
• Shaka ubufasha : Trimethylaminuria ni indwara idakunze kugaragara, bityo ushobora kumva uri wenyine kandi uri wenyine. Kubwibyo, bishobora kuba ubufasha bukomeye guhuza n'amatsinda y'abaterankunga aho abandi bafite ikibazo nk'icyo bashobora kuboneka .

Ni ryari ngomba kubonana na muganga wanjye?

Niba ibimenyetso byawe bitaragabanuka ndetse na nyuma yo guhindura imirire yawe no kugabanya imihangayiko, menya neza ko wagiye kwa muganga. Ashobora kukubwira ubundi buryo bwo kuvura ushobora gutekerezaho.

Ni ibihe bibazo ngomba kubaza muganga wanjye?

Kubera ko trimethylaminuria ari indwara idasanzwe, ushobora kuba utazi byinshi kuri yo. Dore bimwe mu bibazo ushobora kubaza muganga wawe:

• Kuki nageze muri iki kibazo?
• Ni ubuhe buryo bwiza bwo kuvura wangiriye inama?
• Ese ushobora kungira inama itsinda cyangwa gahunda yo gufasha aho nabona ubufasha?

Ese abantu bafite trimethylaminuria bashobora kwihumura ubwabo?

Iki kibazo nacyo ni ikibazo ku bantu benshi. Yego, dukunze kumva ibyuya byacu n'impumuro y'umubiri wacu, kandi abantu bafite `(TMAU)` bashobora kumva impumuro yabo bwite. Ariko, rimwe na rimwe, iyo bamaze kumenyera impumuro yabo bwite, bashobora kutayibona cyane nk'uko abandi babibona. Nanone, si buri wese ushobora kuvuga ko atayiyumva; hari n'abantu bashobora kutamenya ko imibiri yabo ifite impumuro idasanzwe.

Hanyuma, ubutumwa bw'ingenzi cyane

Trimethylaminuria ni indwara ishobora gutuma umuntu atagira icyo akora, atari ku mubiri gusa, ahubwo no mu mutwe . Nubwo itatera ububabare bw'umubiri, ishobora gutera ububabare bukomeye n'inkovu mu mutwe. Hari abantu bafite iyi ndwara bitandukanya na sosiyete kandi bakagerageza kubaho mu bwigunge, batinya ko bazabangamira abandi. Ndetse na nyuma yo guhindura indyo yabo no gukurikiza izindi nama, bamwe mu bantu bafite `(TMAU)` bumva ko bakeneye kwirinda ubuzima bwabo. Ubu bwoko bwo kwigunga bushobora gutuma ugira ibintu nko kwiheba no guhangayika.

Wibuke ko utari wenyine . Niba ufite iyi ndwara, ntugire isoni cyangwa ngo utinye gusaba ubufasha kwa muganga wawe. Bashobora gusobanukirwa ibyo urimo kunyuramo kandi bakakubwira gahunda na serivisi bishobora kugufasha. Ubuzima bwawe bwo mu mutwe ni ingenzi kimwe n'ubuzima bwawe bw'umubiri. Rero menya neza ko ubitekerezaho.

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