Wakamboongororwa hemoglobin yako here? Ngatitaurei nezve Hemoglobin Electrophoresis test!

Mhoroi! Nhasi tichataura nezvekuongororwa ropa kungave kutsva kwauri, asi kwakakosha zvikuru pakuongorora zvimwe zvirwere. Iyi bvunzo inonzi Hemoglobin Electrophoresis . Pamwe chiremba wako akakukumbira kuti uite bvunzo iyi, kana kuti wakambonzwa zita iri pane imwe nzvimbo. Kunyangwe zita racho rakareba zvishoma, usatya! Zviri nyore kwazvo. Tichataura nezvazvo zvese zvakajeka muchinyorwa chino nhasi.

Chii chinonzi Hemoglobin Electrophoresis?

Zvichitaurwa zviri nyore, iyi inzira yekuongorora puroteni inonzi hemoglobin iri mukati memasero edu matsvuku eropa. Ungayeuka kuti hemoglobin ipuroteni inokosha inotakura okisijeni mumiviri yedu yese uye inopa masero matsvuku eropa ruvara rwawo rutsvuku. Kugadzirwa kwakakodzera kwehemoglobin iyi kunodzorwa nemajini edu.

Zvisinei, dzimwe nguva, shanduko dzakati, kana kuti kuchinja-chinja, zvinogona kuitika mumajini anodzora hemoglobin. Kana izvi zvikaitika, panzvimbo pemasero matsvuku eropa ane hutano, masero matsvuku eropa akakuvara, asingashande zvakanaka anotanga kuumbwa. Masero aya akakuvara anoputsika nekukurumidza, izvo zvinogona kutungamira kumamiriro akaita seanemia , kana zvirwere zvakakomba zvine chekuita neropa zvakaita se sickle cell anemia ne thalassemias .

Saka, bvunzo iyi ye hemoglobin electrophoresis inobvumira vanachiremba kuona kana mamiriro ezvinhu akadaro aripo. Zvakare, bvunzo iyi ndeimwe yemiedzo mishoma inoitirwa vacheche. Inobatsira mukuona nekukurumidza zvirwere zvisingawanzoitiki asi zvinogona kunge zvakakomba senge sickle cell anemia.

Ndeupi musiyano uripo pakati pekuongorora hemoglobin ne hemoglobin electrophoresis?

Apa ndipo panovhiringidzika vanhu vazhinji. Kuongororwa kwe hemoglobin kwakajairika kunoyera huwandu hwe hemoglobin mumasero matsvuku eropa rako. Kureva kuti, kunoongorora kana hemoglobin yako yakaderera, yakakwira, kana kuti yakajairika.

Zvisinei, bvunzo ye hemoglobin electrophoresis inoita chimwe chinhu chakadzama kupfuura izvozvo. Inoongorora mhando dzakasiyana dze hemoglobin dziri mumasero matsvuku eropa rako, uye kuti ingani yerudzi rumwe nerumwe iripo. Unonzwisisa musiyano here? Mumwe anotarisa huwandu, mumwe anotarisa mhando nehuwandu hwemhando idzodzo.

Saka, ndeapi marudzi aya ehemoglobin?

Vanachiremba vanowanzo tarisa mhando ina huru dze hemoglobin muongororo iyi. Ngatidzidzei zvishoma nezvadzo.

• Hemoglobin A1 naA2 (HgbA1 naHgbA2): Rudzi urwu rwehemoglobin, runonzi hemoglobin A1, ndirwo rwakawanda mumasero matsvuku eropa emunhu mukuru ane hutano. Hemoglobin A2 imhando diki, inoumba inenge 2% kusvika 3% yehemoglobin yese. Idzi dzinonziwo "hemoglobin dzevakuru."

• Hemoglobin F (HgbF): Iyi inonzi "Hemoglobin yemwana asati aberekwa"Sezvinoratidzwa nezita racho, rudzi urwu rweHgbF runowanikwa mumasero matsvuku eropa evana vari mudumbu, vacheche, nevana vane makore angangoita matatu. Zvisinei, zvinogona kuva zvisina kujairika kuva neHgbF yakakwira kupfuura yakajairika muropa remunhu mukuru.

• Hemoglobin S (HgbS): Rudzi urwu rwehemoglobin chinhu chikuru chinowanikwa mu sickle cell anemia . Sickle cell anemia chirwere chakakomba chiri muboka rezvirwere zve sickle cell . Chirwere ichi chinowanzoitika kuvanhu vanobva kuAfrica . HgbS inokonzera kuti masero matsvuku eropa achinje kuita chimiro che sickle, izvo zvinogona kuvhara mitsipa yeropa.

• Hemoglobin C (HgbC): Rudzi urwu rwehemoglobin runobatanidzwa nechirwere chinonzi hemolytic anemia . Ichi chirwere umo masero matsvuku eropa anoparadzwa nekukurumidza kupfuura masero akajairwa kana kuti hupenyu hwavo hunopfupikiswa. Kufanana ne sickle cell anemia, chirwere ichi cheHgbC chinowanzoitikawo kuvanhu vane dzinza reAfrica .

Zvino zvave pachena kwauri kuti kune mhando dzakasiyana dzehemoglobin, uye mhando imwe neimwe ine mabasa ayo chaiwo uye mhedzisiro.

Kuongororwa uku kunoitwa sei? Ropa rinotorwa sei?

Kuti tiite bvunzo iyi, tinongoda ropa chete. Vanachiremba, kune nzira dzakawanda dzekutora ropa iri. Ngationei kuti ndedzipi.

1. Kutorwa kweropa mutsinga

Iyi ndiyo nzira inowanzo shandiswa kuunganidza ropa kubva kuvanhu vakuru nevana vakuru. Ungave wakapa ropa nenzira iyi.

• Kutanga, mukoti kana chiremba achachenesa nzvimbo iri patsinga yako paruoko rwako nedoro.
• Zvadaro, vanoisa tourniquet paruoko rwako, vorusimbisa, uye vokukumbira kuti udzvinyirire ruoko rwako. Izvi zvichaita kuti tsinga dzionekwe zviri nyore uye zvinoita kuti zvive nyore kuburitsa ropa.
• Tevere, mukoti anopinza tsono mutsinga. Panguva iyi, unganzwa kurwadziwa kudiki, sekunge warumwa nesvosve. Asi zvinongotora masekondi mashoma chete.
• Unganidza ropa rinodiwa mubhodhoro diki woritumira kurabhoritari kuti riongororwe.
• Mushure mekutorwa kweropa, plaster diki inoiswa panzvimbo yakapinzwa tsono. Nzvimbo yacho inogona kunge yakakuvara zvishoma uye inogona kutoita bhuruu kwemazuva mashoma. Izvi zvakajairika, musazvidya moyo.

2. Chimuti chemunwe

Nzira iyi inowanzo shandiswa kutora ropa revana vadiki.

• Izvi zvinosanganisira kubaya muromo wemunwe wemwana nechinhu chidiki uye kutora madonhwe mashoma eropa.
• Ropa rinoiswa pamutsetse wekuyedza wakagadzirwa zvakanaka kana mubhodhoro diki.
• Dzimwe nguva, kune michina inogona kuunganidza ropa uye kuriisa panguva imwe chete. Iyi inzira inokurumidza uye iri nyore.

3. Chitsitsinho chetsitsinho

Izvi zvinoitwa sechikamu chekuongororwa kwehutano hwemwana achangoberekwa. Kuongororwa uku kunowanzoitwa mukati memaawa makumi mana nemasere kubva pakuzvarwa kwemwana.

• Muizvi, tsono diki inopinzwa pasi pechitsitsinho chemwana uye madonhwe mashoma eropa anowanikwa.
• Panguva iyi, amai kana baba vanogona kubata mwana. Ipapo mwana achanzwawo kunyaradzwa.
• Ropa rinotorwa roendeswa kurabhoritari mushure mekunge razorwa papepa.
• Miedzo iyi inoshandiswa kuongorora vacheche vachangoberekwa kuti vaone kana paine zviratidzo zvezvirwere zvisingawanzoitiki asi zvinorapika zvakaita se sickle cell anemia, zvinoreva kuti vane hemoglobin yakasiyana-siyana.

Ropa iri richaongororwa sei murabhoritari?

Zvakanaka, ikozvino tatora ropa. Chii chinozoitika? Murabhoritari, marudzi aya ehemoglobin anopatsanurwa uye anowanikwa nenzira inonakidza kwazvo. Izvozvo zvinonzi kushandisa magetsi . Mhando huru dzehemoglobin dzine magetsi akasiyana.

Heino maitiro ebvunzo iyi anowanzo shanda:

• Kutanga, masero matsvuku eropa anoparadzaniswa kubva muropa obva anyungudika. Muenzaniso uyu wemasero matsvuku eropa anonyungudika unoiswa pachidimbu chakakosha, chakadai sechidimbu che cellulose .
• Zvadaro, chidimbu chine muenzaniso chinoiswa mumuchina unonzi electrophoresis chamber . Muchina uyu unopfuura nemagetsi kuburikidza nemumuenzaniso.
• Mukupindura kumagetsi, marudzi ehemoglobin ane magetsi akasiyana anoparadzana uye anofamba achitevedza strip nekumhanya kwakasiyana.
• Pakupedzisira, marudzi aya ehemoglobin akaparadzaniswa anoonekwa semabhandi ane mavara akasiyana pamutsara.
• Tevere, nyanzvi dzezvekurapa dzinoenzanisa mhinduro idzi nemhedzisiro yemuenzaniso we hemoglobin wakajairika kubva kumunhu ane hutano.
• Kana huwandu hwemhando ye hemoglobin hwakakwira zvakanyanya kana kuti hwakaderera pane hwakajairwa, zvinogona kuva chiratidzo chechirwere cheropa. Semuenzaniso, kana rudzi rwako rwe hemoglobin S (HgbS) ruchiratidzika zvakasiyana neHgbS yemunhu akajairwa, zvinogona kuva chiratidzo chekuti une sickle cell anemia.

Funga nezvazvo nenzira iyi, sekunge paunokanda matombo ane huremu hwakasiyana murwizi rwemvura, matombo acho anofamba daro rakasiyana zvichienderana nehuremu hwawo. Pano, magetsi anoita se "rwizi rwemvura" irworwo.

Ndeupi musiyano uripo pakati pe isoelectric focus (IEF) ne electrophoresis?

Isoelectric focusing (IEF) imwe nzira inoshandiswa kuona mhando dzisina kujairika dzehemoglobin. IEF ne electrophoresis zvese zvinoshandisa magetsi emagetsi kuparadzanisa mhando dzehemoglobin. Zvisinei, pane musiyano wehunyanzvi pakati penzira mbiri idzi. Dzimwe nguva, nzira dzese dzinogona kushandiswa kuona mhando dzehemoglobin nemazvo.

Zvinotora nguva yakareba sei kuti mushumo usvike?

Bvunzo iyi inogona kutora inenge awa kuti ipedzwe murabhoritari. Zvisinei, zvinogona kutora mazuva mashoma kuti chiremba wako agamuchire zvabuda, azviongorore, uye akutsanangurire. Saka usatarisira mushumo wacho nekukasika mushure mekuongororwa. Chiremba achakuudza zuva raunofanira kuuya kuzotora mushumo wacho.

Mushumo wangu unorevei? Ndinounzwisisa sei?

Ichi ndicho chinhu chakakosha. Mushumo wako we hemoglobin electrophoresis unoratidza huwandu hwakasiyana hwe hemoglobin yega yega. Semuenzaniso, kana huwandu hwako hwe hemoglobin F (HgbF) hwakakwira zvakanyanya kupfuura zvakajairwa, zvinogona kuva chiratidzo cheimwe mhando ye thalassemia.

Asi, unofanira kurangarira izvi zvakanaka:

Usasarudza chero chirwere chipi zvacho zvichibva panhamba dziri mumushumo. Icho chikamu chimwe chete chekuongororwa. Munhu akanakisa kunzwisisa zviri mumushumo wako uye kuti zvinokanganisa sei hutano hwako ndichiremba wako . Iye achaongorora zvese kubva pazviratidzo zvako, mimwe mhedzisiro yebvunzo, uye nhoroondo yako yehutano kuti aongorore chirwere chako nemazvo.

Kana paine zvinhu zvisina kumira zvakanaka mumushumo wangu, ndofonera chiremba here?

Ehe, zvechokwadi. Kana wakaongororwa hemoglobin electrophoresis nekuda kwezviratidzo (semuenzaniso, kuneta nguva dzose, kucheneruka, kushaya mweya), unofanira kuona chiremba wako nekukasika kuti mukurukure zvakabuda mumushumo wacho.

Kuongororwa kwe hemoglobin electrophoresis kunotipa mufananidzo wemhando dze hemoglobin muropa rako panguva iyoyo. Mazinga e hemoglobin inzira yekuongorora puroteni iyi inokosha mumasero edu matsvuku eropa. Kuchinja kusingawanzoitiki pahuwandu hwe hemoglobin yerudzi rwakati kunogona kuva chiratidzo chekuti ungave uine chirwere.

Kana zvabuda muongororo yako kana yemwana wako zvichiratidza kuti une chirwere chakakomba, zviri nyore kuti unzwe wakaremerwa uye uchitya nekungotarisa mufananidzo wacho. Kunyanya kana zviri zveutano hwemwana wako mudiki kana achangoberekwa, zvakajairika kuti unzwe wakaremerwa. Asi edza kutarisa mufananidzo mukuru pane kutya. Munhu akanakisa wekukubatsira nazvo ndichiremba wako. Iye anogona kutsanangura kuti "mufananidzo" uyu unoenderana sei nehutano hwako hwese uye zvaunofanira kuita zvinotevera.

Mharidzo Yekuenda Nayo Kumba

Ndinovimba wava kunzwisisa zvakanaka bvunzo ye hemoglobin electrophoresis yatakakurukura nhasi. Heano zvinhu zvishoma zvekurangarira:

• Hemoglobin electrophoresis inzira yakakosha yekuongorora ropa inoratidza mhando dzakasiyana dzehemoglobin muropa nehuwandu hwadzo.
• Izvi zvinobatsira kuongorora zvirwere zvine chekuita neropa zvakaita se sickle cell anemia uye thalassemia .
• Mwana achangoberekwaIzvi zvinoitwawo sechikamu chekuongororwa kwehutano.
• Mhando dzeHemoglobin dzinopatsanurwa nekutora ropa uye kushandisa magetsi .
• Gara uchitaura nachiremba wako, kwete kuedza kunzwisisa zvabuda mumushumo wacho wega.
• Kana mhedzisiro yacho isina kujairika, usavhunduka uye tevera mirairo yachiremba wako. Kuonekwa nekukurumidza ndiyo nhanho yekutanga yekurapwa kunobudirira.

Tinovimba kuti ruzivo urwu ruchakubatsira. Ramba uine hutano hwakanaka!

Hemoglobin Electrophoresis, Hemoglobin, Masero Matsvuku Eropa, Kushaya Maropa, Kushaya Maropa Kwemasero Echirwere Chekurwara, Thalassemia