Chii chinonzi Aldosterone? Ngationei kuti inokanganisa sei BP yako!

Wakambonzwa nezveAldosterone here? Pamwe chiremba wako akataura nezvazvo, kana kuti pamwe wakambonzwa zita racho paaitaura nezveBP yako. Chaizvoizvo ihormone diki asi inokosha kwazvo mumiviri yedu. Inobatsira kudzora huwandu hwesodium nepotassium mumiviri yedu uye inochengetedza BP yedu ichidzikamiswa. Saka, ngatitaurei nezveAldosterone nhasi nenzira iri nyore yaunogona kunzwisisa, zvakanaka here?

Chii chinonzi aldosterone? Chinobva kupi?

Zvichitaurwa zviri nyore, Aldosterone ihormone inogadzirwa nema adrenal glands ako. Unoziva here kuti aya ma adrenal glands chii? Aya ma glands madiki maviri, akaita setriangle akaita sengowani diki dziri pamusoro peitsvo dzako. Iwo chikamu che endocrine system yedu. Aya ma glands anoburitsa mahormone akawanda akakosha kumiviri yedu.

Mahormone akafanana nemakemikari anotungamira mashandiro emiviri yedu. Anofamba nemuropa oudza nhengo, tsandanyama, nedzimwe nhengo dzemuviri zvekuita uye nguva yekuzviita.

Zvino, homoni iyi, Aldosterone, inodzora huwandu hwesodium nepotassium muropa rako. Sodium nepotassium idzi dzinonzi electrolytes . Izvi ndizvo zvinobatsira kuchengetedza mvura yemuviri yakaringana uye zvinobatsira tsinga netsandanyama kushanda zvakanaka. Zvakare, Aldosterone inodzora huwandu hwemvura inotorwazve neitsvo. Izvi zvinowedzera huwandu hweropa uye zvinokanganisa BP.

Saka, kungave mazinga e aldosterone ako akaderera kana akakwira, zvinogona kukanganisa hutano hwako.

Chii chinoitwa nealdosterone mumuviri wedu?

Basa guru reAldosterone nderekubatsira kudzora BP yako. Rinobatsira pabasa iri rinokosha nenzira dzakasiyana-siyana:

• Aldosterone inoudza nhengo dzakadai seitsvo dzako neura kuti dziwedzere huwandu hwesodium inowedzerwa muropa rako kana kuti kuwedzera huwandu hwepotassium inobuda muweti yako.
• Kana huwandu hwesodium muropa hukawedzera nenzira iyi, muviri unotanga kuchengetedza mvura, izvo zvinowedzera huwandu hweropa.

Zvese izvi zvakakosha, kana BP yakaderera, kuti idzoke padanho rakanaka.

Nenzira isina kunanga, aldosterone inobatsirawo kuchengetedza pH (kureva acid-base balance) uye mazinga e electrolyte muropa rako.

Mazinga e aldosterone anodzorwa sei? Ngatinyatsoongororai!

Aldosterone chikamu che network yakaoma yemahormone, ma enzyme, mapuroteni, uye maitiro anonzi Renin-Angiotensin-Aldosterone System (RAAS) . Ndiyo inonyanya kukosha pakudzora BP.

Funga nezveizvi senzira yekutevera nhanho nhanho:

1. Chekutanga, kana BP yako yadzikira , enzyme inonzi renin inoburitswa muropa rako kubva muitsvo dzako.

2. Renin iyi inopwanya puroteni inonzi angiotensinogen , inogadzirwa muchiropa chako. Chimwe chezvidimbu izvi iangiotensin I. Izvi hazvishande panguva iyoyo, zvinoreva kuti hazvina basa rakawanda.

3. Zvadaro, Angiotensin-Converting Enzyme (ACE) inobva mumapapu ako inouya yopwanya iyi Angiotensin I kuita zvidimbu zvakawanda. Chimwe chezvidimbu izvozvo ihormone inoshanda inonzi Angiotensin II .

4. Apa ndipo panoita basa rinokosha Angiotensin II :

• Chimwe chacho ndechekuwedzera BP nekuita kuti madziro etsinga diki dzeropa (arterioles) agumbuke.
• Chimwe ndechekuti "inopa chiratidzo" kuma "adrenal glands" ako kuti abudise aldosterone.
• Inoudzawo pituitary gland yako kuti iburitse Antidiuretic Hormone (ADH) , inozivikanwawo seVasopressin .

5. Saka, Aldosterone neADH zvinoshanda pamwe chete kuudza itsvo kuti dzichengetedze sodium mumuviri. Aldosterone inoita kuti itsvo dzibudise potassium muweti. Kana huwandu hwesodium muropa hukawedzera, mvura inochengetwa mumuviri. Izvi zvinowedzera huwandu hweropa neBP.

Iyi ndiyo nzira iyo Renin-Angiotensin-Aldosterone System inopedzwa nayo. Unonzwisisa here maitiro iwayo?

Sisitimu iyi inogona zvakare kushandiswa nemamwe mahormone akadai se corticosteroids , estrogen, uye thyroid hormones .

Kana paine dambudziko nechero chikamu chemuviri uyu, rinogona kukanganisa BP yako uye huwandu hwesodium nepotassium. Zvisinei, zvakakosha kuyeuka kuti zvimwe zvinhu zvakawanda zvinogona kukanganisawo BP yako, zvakaita secholesterol yakakwira, majini, uye mimwe mishonga.

Nzira yekuongorora mazinga ealdosterone?

Bvunzo huru inoshandiswa navanachiremba kuti vaongorore matambudziko ane chekuita nealdosterone ndeyeAldosterone: Renin Ratio Test . Nekuti renin nealdosterone zvakabatana, bvunzo iyi inogona kuona kana dambudziko riri dambudziko rekugadzirwa uye mashandiro ealdosterone, kana kuti pane dambudziko nerenin-angiotensin system pachayo.

Pakuongorora uku kweAldosterone: Renin Ratio, ropa rinotorwa kubva mutsinga iri muruoko rwako.

Vanachiremba vanogonawo kuyera huwandu hwealdosterone muropa rako uye/kana weti.

Dzimwe nguva, chiremba wako anogona kuraira bvunzo yekuisa catheter kuti atore ropa kubva mutsinga iri muitsvo yako (ye renin) kana mutsinga iri muadrenal gland yako (ye aldosterone). Iyi bvunzo inoitirwa muchipatara na radiologist akadzidziswa zvakanyanya.

Ndeapi mazinga e aldosterone akajairika?

Kuyera kwakajairika kwemazinga ealdosterone kunogona kusiyana zvishoma kubva murabhoritari imwe kuenda kune imwe. Saka, iva nechokwadi chekutarisa huwandu hwakajairika pamushumo wako werabhoritari, kana kubvunza chiremba wako kana uine mibvunzo nezvemhedzisiro yako.

Mwero we aldosterone muropa unosiyana zvichienderana nezera. Kazhinji, mwero we aldosterone muropa unotevera:

• Kune vacheche vane mwedzi 1 kusvika ku12: 5.8 - 110.0 nanograms pa deciliter (ng/dL)
• Kune vana vane makore 1 kusvika ku5: < 36.0 ng/dL
• Kune vana vane makore matanhatu kusvika mapfumbamwe: < 24.0 ng/dL
• Kune vana vane makore gumi kusvika gumi nerimwe: < 15.0 ng/dL
• Kune vana vane makore 12 kusvika ku14: < 22.0 ng/dL
• Kune vechidiki vane makore 15 kusvika 17: 3.0 - 32.0 ng/dL
• Vakuru vane makore 18 kusvika 99 ekuberekwa: 3.1 - 35.4 ng/dL

Kana uchitarisa huwandu hwealdosterone muongororo yeweti yemaawa makumi maviri nemana, huwandu hwakajairika huri pakati pe3 - 25 micrograms pamaawa makumi maviri nemana (3 - 25 mcg/maawa makumi maviri nemana).

Chii chinoitika kana huwandu hwealdosterone hukawedzera?

Kana mazinga e aldosterone akakwira kupfuura akajairwa, tinoadaidza kuti hyperaldosteronism .

Chikonzero chikuru cheizvi iPrimary Aldosteronism , inozivikanwawo seConn's syndrome . Dambudziko iri rinokonzerwa nebundu risiri rekenza (risingakuvadzi) rinowanzo buda mune rimwe rema adrenal glands ako.Izvi zvinoita kuti gland ibudise aldosterone yakawanda kupfuura yainofanira kuita. Kana mazinga ealdosterone akawedzera, mazinga e sodium anowedzera ( hypernatremia ) uye mazinga e potassium anoderera ( hypokalemia ). Izvi zvinogona kukonzera kusawirirana kwema electrolyte.

Zviratidzo zve aldosterone yakakwira

Kana paine aldosteronism yekutanga, ndiko kuti, kana mazinga e aldosterone akakwira, zviratidzo zvakaita se:

• Kukwira kweropa (BP)
• Musoro
• Kushaya simba kwetsandanyama , kunyanya kana potassium yakawanda zvakanyanya
• Nyota zvakanyanya uye kuita weti kakawanda

Kana uine zviratidzo izvi, zvakakosha zvikuru kutsvaga rubatsiro rwechiremba nekukasika.

Chii chinoitika kana huwandu hwealdosterone hukadzikira?

Kana mazinga e aldosterone akaderera pane akajairwa, tinoadaidza kuti hypoaldosteronism . Uku kushomeka kwe aldosterone, kana kuti kusashanda zvakanaka kwayo. Kana mazinga e aldosterone akaderera, mazinga e sodium anoderera ( hyponatremia ), mazinga e potassium anowedzera ( hyperkalemia ), uye muviri unoburitsa acid yakawandisa ( metabolic acidosis ).

Kune zvikonzero zvakawanda zvinogona kukonzera hypoaldosteronism:

• Chirwere cheAddison: Ichi chirwere chisingawanzoitiki. Chinonziwo Primary Adrenal Insufficiency . Ichi chirwere chinokonzerwa ne autoimmune . Izvi zvinoreva kuti masoja emuviri wako anorwisa chikamu chekunze (cortex) cheadrenal glands. Mahormone ese ari maviri aldosterone ne cortisol anogadzirwa ipapo. Izvi zvinoita kuti huwandu hwemahormone ese ari maviri huderere.
• Congenital Adrenal Hyperplasia (CAH): Iri iboka rezvirwere zvemajini zvinokanganisa magland eadrenal. Vanhu vane CAH vanozvarwa vasina mamwe ma enzyme anodiwa kugadzira mahormone anogadzirwa nemagland eadrenal.
• Mamwe matambudziko ehutano: Vanhu vane chirwere cheshuga, chirwere cheitsvo, chepfu yemutobvu, kana zvirwere zvakakomba vanogona kuva ne hypoaldosteronism.
• Mimwe mishonga: Mishonga isingashandisi steroidal inorwisa kuzvimba (NSAIDs) , HeparinDambudziko iri rinogonawo kukonzerwa nemishonga inopihwa kurapa chirwere chemwoyo.

Zviratidzo zve aldosterone yakaderera

Kazhinji, mazinga akaderera ealdosterone (Hypoaldosteronism) anogona kukonzera zviratidzo zvakaita se:

• Kuderera kweropa (Hypotension)
• Kushaya simba kwetsandanyama
• Kusvotwa
• Kurova kwemoyo
• Kusarongeka kwekurova kwemoyo (Arrhythmia)

Zvichienderana nechikonzero chekushaya kwako aldosteronism, unogona kunge uine zvimwe zviratidzo. Semuenzaniso, muchirwere cheAddison, huwandu hwakaderera hwe cortisol hunogona kukonzera shanduko dzeganda (senge mavara matema uye mapete eganda) uye huwandu hwakaderera hweshuga muropa ( hypoglycemia ).

Kana uine chimwe chezviratidzo izvi, enda kuna chiremba wako nekukasika.

Pakupedzisira, zvinhu zvekurangarira (Mharidzo Yekuenda Kumba)

Aldosterone ihormone inokosha pakudzora BP. Kana uchinetseka kuchengetedza BP yakanaka uye uine shanduko mumazinga ako epotassium muropa, zvakanaka kutaura nachiremba wako nezvedzimwe nzira dzekugadzirisa BP uye mimwe miedzo. Anogona kuraira bvunzo kuti aone kana zviratidzo zvako zvichikonzerwa nemazinga asina kujairika ealdosterone.

Ndinovimba ruzivo urwu ruchakubatsira! Ramba uine hutano hwakanaka!

Aldosterone , Aldosterone, Mahormone, Kumanikidzwa kweropa, Adrenal glands, Sodium, Potassium