Unonzwa kuneta uye kuneta zvakanyanya zuva nezuva here? Pamwe chete nekurwadziwa mudumbu uye kuda kurutsa, dzimwe nguva unonzwa uchida chikafu chine munyu here? Kunyangwe izvi zvingaita sezvinhu zvakajairika, pamwe zviri shure kweizvi pane chirwere chatisati tanzwa zvakawanda nezvacho, asi chinofanira kutarisirwa nemazvo. Nhasi tiri kutaura nezvechimwe chirwere chakadaro, chirwere cheAddison.
Chii chaizvo chinonzi chirwere cheAddison?
Zvichitaurwa zviri nyore, chirwere cheAddison chirwere chisingaperi chinoitika kana ma adrenal glands mumuviri wedu asingagadzi mahormone maviri akakosha, cortisol nealdosterone .
Zvino ungave uchishamisika kuti adrenal glands chii. Aya magland maviri madiki, ane mativi matatu anogara pamusoro peitsvo dzedu. Iwo chikamu chakakosha chehurongwa hwe endocrine hwemuviri wedu.
- Cortisol: Hormone iyi inokosha muhupenyu hwedu. Fungidzira kana uchirwara, ukaita tsaona, kana kuvhiyiwa, muviri wako unonzwa kushushikana kwakanyanya. Panguva dzakadai, homoni yecortisol inobatsira muviri kurarama nekushushikana ikoko. Kwete izvozvo chete, asi inobatsirawo kudzora BP, mashandiro emwoyo, masoja emuviri, uye huwandu hweshuga muropa.
- Aldosterone: Homoni iyi inodzora kuenzana kwe sodium (munyu) ne potassium muropa redu. Inodzorawo huwandu hwemvura inobuda muitsvo dzedu seweti. Izvi zvinokanganisa zvakananga huwandu hweropa redu neBP yedu.
Chirwere cheAddison chinozivikanwawo seprimary adrenal insufficiency . Kune chimwe chirwere chakafanana chinonzi secondary adrenal insufficiency . Mumamiriro ezvinhu aya, pituitary gland iri muuropi haigadzi hormone yakakwana inonzi ACTH . Iyi hormone, ACTH, inokurudzira adrenal glands kuti igadzire cortisol.
Chii chakasiyana pakati pechirwere cheAddison nechirwere cheCushing?
Usavhiringe zvinhu zviviri izvi. Zviri nyore kwazvo.
- Chirwere cheAddison: Kusakwana kwecortisol (uye aldosterone) mumuviri.
- Chirwere cheCushing: Kuwedzera kwecortisol mumuviri.
Ndiani angangonyanya kuva nechirwere ichi?
Kunyangwe chirwere cheAddison chichigona kuitika chero pazera ripi zvaro, chinonyanya kuitika pakati pemakore makumi matatu nemakumi mashanu.Pakati pevanhu. Ichi chirwere chisingawanzoitiki.
Uyewo, vanhu vane zvimwe zvirwere zve autoimmune vari panjodzi huru yekubatwa nazvo. Chirwere che autoimmune chinoitika apo masoja emuviri wedu anorwisa masero edu ane hutano zvisizvo. Vanhu vane zvirwere zvinotevera vari panjodzi huru yekubatwa nechirwere cheAddison:
- Chirwere cheshuga cherudzi rwekutanga
- Kupererwa neropa kwakaipisisa
- Chirwere cheMakuva
- Chirwere chethyroiditis chisingaperi
- Dermatitis herpetiformis
- Vitiligo
- Myasthenia gravis
Ndezvipi zviratidzo zvechirwere cheAddison?
Muchirwere ichi, kukuvara kweadrenal glands kunowanzoitika zvishoma nezvishoma, nekufamba kwenguva. Nokudaro, zviratidzo zvinoonekwa zvishoma nezvishoma. Zviratidzo izvi zvinogona kusiyana kubva pamunhu kusvika pamunhu.
| Chiratidzo | Tsananguro |
|---|---|
| Kunzwa kuneta kwakanyanya nguva nenguva | Ichi chiratidzo chinowanzoitika uye chinowedzera zvishoma nezvishoma. |
| Mavara matema paganda (Hyperpigmentation) | Kusviba kweganda, kunyanya pedyo nemaronda, mavanga, ganda rakapetana (magokora, mabvi), uye mazino. |
| Kurwadziwa kwemudumbu, kuda kurutsa, uye kurutsa | Matambudziko ekugaya chikafu. |
| Kuzvimba (manyoka) | Kurwadziwa mudumbu nguva nenguva pamwe nemanyoka. |
| Kurasikirwa nechido chekudya uye kudzikira kwehuremu | Kudzikira kwehuremu uye kushaya chido chekudya pasina chikonzero chakajeka. |
| Kurwadziwa kwetsandanyama nemajoini | Zvirwere zvakaita sekurwadziwa kwemuviri uye kugwinha kwetsandanyama. |
| Kuderera Kweropa | Kunzwa dzungu uye kupera simba kana wakamira. |
| Kuda munyu zvakanyanya | Chiratidzo chinokonzerwa nekudzikira kwehuwandu hwemunyu mumuviri. |
| Shuga shoma muropa (Hypoglycemia) | Zviratidzo zvakaita sekurwadziwa kwemuviri nekudikitira zvinogona kuitika. |
| Kuchinja kwepfungwa | Hasha dzisingatsananguriki, kuora mwoyo, uye kuoma kwekuisa pfungwa pachinhu chimwe chete. |
Kana vakadzi vaine chirwere ichi, vanogonawo kuona zviratidzo zvakaita sekuenda kumwedzi zvisina kurongeka, kurasikirwa nebvudzi mumuviri, uye kudzikira kwechido chebonde.
Dambudziko reAddisonian: Chii chinonzi Addisonian Crisis?
Dzimwe nguva, kunyanya panguva yekushushikana kukuru mumuviri (semuenzaniso, chirwere chakakomba, tsaona), zviratidzo zvinogona kungoerekana zvawedzera uye zvova zvinotyisidzira hupenyu. Izvi zvinonzi Addisonian crisis , kana kuti acute adrenal failure .
Iyi inyaya yekurapwa. Kana ikasarapwa zvakanaka, kuvhunduka uye kunyange kufa zvinogona kuitika.
Kana iwe kana mumwe munhu waunoziva aine zviratidzo zvinotevera, muendese kuchipatara chiri pedyo neEmergency Department (ETU) nekukasika.
| Zviratidzo zvekuyambira nezvedambudziko reAddisonian | |
|---|---|
| 1. | Kuneta kwakanyanya uye kushaya simba kamwe kamwe. |
| 2. | Kurwadziwa kwakakomba kamwe kamwe mudumbu, musana, kana makumbo. |
| 3. | Kurutsa zvakanyanya uye manyoka, zvichikonzera kupera mvura mumuviri. |
| 4. | Kuderera kweropa kwakaderera zvakanyanya. |
| 5. | Kunzwa kuvhiringidzika mupfungwa, kusagadzikana, kana kutya. |
| 6. | Kurasikirwa nepfungwa. |
Chii chinokonzera chirwere cheAddison?
Chikonzero chikuru chechirwere cheAddison imhinduro ye autoimmune . Zvichitaurwa zviri nyore, masoja emuviri wedu ekudzivirira (masoja ekudzivirira muviri) anorwisa zvisizvo nhengo dzedu dzine hutano. Muchirwere ichi, masoja ekudzivirira muviri anorwisa chikamu chekunze cheadrenal glands (adrenal cortex). Apa ndipo panogadzirwa cortisol nealdosterone. Zviratidzo hazviwanzoonekwa kusvika 90% yekukuvara uku kwaitika. Izvi zvinogona kutora mwedzi, kana kunyange makore. Ichi ndicho chikonzero che75% yevarwere veAddison.
Kare, chirwere cherurindi ndicho chainyanya kukonzera izvi, uye chichiri kukonzera zvirwere munyika dzichiri kusimukira.
Kune zvimwe zvikonzero zvisingawanzoitiki:
- Zvirwere zvakaita seHIV/AIDS uye hutachiona hwefungus.
- Kupararira kwemasero ekenza kubva kune dzimwe nzvimbo kuenda kuma adrenal glands.
- Kubuda ropa muadrenal glands (kubuda ropa).
- Kuvhiyiwa kubviswa kweadrenal glands.
- Zvirwere zvakaita seamyloidosis.
Chiremba anoongorora sei chirwere ichi?
Nekuti zviratidzo zvinoonekwa zvishoma nezvishoma uye zvakajairika kune zvimwe zvirwere zvakawanda, zvinogona kuoma kuona chirwere ichi nemazvo.
Kazhinji, chiremba anotanga kunyumwa kana kuongororwa ropa nguva dzose kuchiratidza kuti mune sodium shoma kana kuti potassium yakawanda muropa. Mavara matema paganda chimwe chiratidzo chikuru chinoita kuti munhu afungidzire izvi.
Kana chiremba wako achifungidzira kuti chirwere cheAddison chakakonzerwa nezviratidzo zvako, acharaira mimwe miedzo yakawanda kuti asimbise chirwere chacho.
- Kuongororwa kweropa: Izvi zvinoyera huwandu hwemahormone e sodium, potassium, cortisol, uye ACTH muropa rako.
- Kuongororwa kweACTH stimulation: Izvi zvinosanganisira kubaya jekiseni reACTH rekugadzira uye kutarisa kana adrenal glands yako ichiburitsa cortisol. Kuderera kwecortisol kunogona kuratidza kuti maglands haashande zvakanaka.
- Kuongororwa kwehypoglycemia kunokonzerwa neinsulin: Izvi zvinotarisa kana dambudziko rako rine chekuita negland repituitary.
- CT scan: Izvi zvinogona kutarisa kukuvara kweadrenal glands kana hutachiona.
Ndezvipi zvinorapwa izvi?
Chirwere cheAddison chinorapwa nekutsiva mahormone ari kushaikwa mumuviri nemishonga yakagadzirwa.
- Mushonga unonzi hydrocortisone unopiwa panzvimbo pe cortisol.
- Aldosterone inotsiviwa nemushonga unonzi fludrocortisone .
Chirwere cheAddison chirwere chisingaperi, saka uchafanira kunwa mishonga iyi kweupenyu hwako hwese .
Chipimo chemushonga uyu chinosiyana kubva pamunhu kusvika pamunhu. Zvakare, chiremba wako anogona kuwedzera chiyero chemushonga kudzivirira dambudziko reAddisonian kana ukasangana nekushushikana, senge hutachiona, tsaona, kana kuvhiyiwa.
Kana uine chirwere cheAddison, unochengetedza sei hutano hwako?
Kana uine chirwere ichi, zvakakosha kuti uzvitarisire.
- Gara wakapfeka kadhi reID kana bracelet yekuzivisa chiremba kuitira kuti vanachiremba vazive nezvemamiriro ako ezvinhu kana paine emergency.
- Taura nachiremba wako nezve zvekuita kana uchirwara kana kuti uri mukushushikana kwakanyanya, sezvo mwero wemushonga wako ungangoda kugadziriswa panguva dzakadai.
- Kana paine emergencyBvunza chiremba wako nezvekuti ungaisa sei jekiseni re cortisol muropa rako uye kudzidzisa mumwe wemumhuri yako kuti ungaripa sei.
Unofanira kuona chiremba wako rini?
Kana uine chirwere cheAddison, unofanira kuona chiremba wako (kazhinji chiremba we endocrinologist) nguva nenguva kuti uve nechokwadi chekuti mushonga wako wakakunakira.
Kana ukasangana nedambudziko guru rekushushikana, senge tsaona, kurwara, kana kufa kwemudiwa wako, fonera chiremba wako nekuti ungangoda kuchinja mwero wemushonga wako.
Kana zviratidzo zvedambudziko reAddisonian (zvakadai sekushaya simba kwakakomba, kurwadziwa kwakanyanya) zvikaitika, enda kuchipatara nekukurumidza kuEmergency Department (ETU) kuti unorapwa.
Kuziva kuti une chirwere chisingaperi kunogona kushungurudza mupfungwa. Asi mashoko akanaka ndeekuti chirwere cheAddison chinogona kurapwa zvinobudirira nemishonga. Nekuona chiremba wako nguva dzose, kutora mushonga wakakodzera, uye kuzvitarisira, unogona kurarama hupenyu hwakanaka uye hwakajairika.
Mharidzo Yekuenda Nayo Kumba
- Chirwere cheAddison chirwere chisingawanzoitiki uye chisingaperi umo ma adrenal glands asingagadzi mahormone e cortisol ne aldosterone akakwana.
- Zviratidzo zvikuru zvinosanganisira kuneta kunowedzera, mavara matema paganda (kunyanya parinopetana ganda), uye kuda chikafu chine munyu zvakanyanya.
- Dambudziko reAddisonian idambudziko rezvehutano rinogona kuisa hupenyu panjodzi, uye kana zviratidzo zvikaitika, unofanira kuenda kuchipatara nekukurumidza.
- Kurapwa kunoda kurapwa kwekutsiva mahormone kwehupenyu hwese.
- Nekutevera mazano akakodzera ekurapa uye kutora mishonga yako sezvakarairwa, unogona kurarama hupenyu hune hutano hwakakwana uye hwakajairika.
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