Une BP yakakwira here, kana kuti yatinoziva se'pressure'? Kana kuti une mvura inochengetwa uye makumbo akazvimba nekuda kwechirwere chakadai sechirwere chemwoyo? Saka chiremba wako angangodaro akakunyorera mushonga wakakosha. Ndiwo mhando yemushonga watichataura nezvawo munyaya ino nhasi, zviri nyore uye zvine hunhu. Tinodaidza kuti Aldosterone Antagonists.
Zvichitaurwa zviri nyore, chii chinonzi Aldosterone Antagonists?
Zvakanaka, ngatinzwisise izvi nenzira iyi. Tine nhengo mbiri diki mumuviri wedu dzinonzi adrenal glands. Idzi dzinogadzira hormone inonzi aldosterone. Basa guru re hormone iyi nderekudzora BP nekuchengetedza munyu nemvura mumuviri kana zvichidikanwa. Izvi hazvisi dambudziko kumunhuwo zvake.
Asi fungidzira, kana mumwe munhu atove neBP yakakwira, kana kuti aine mvura yakawanda mumuviri wake nekuda kwechirwere chemwoyo, iyi aldosterone hormone ichaita kuti mamiriro acho ezvinhu awedzere kuipa.
Ndipo panotibatsira mhando yemishonga inonzi Aldosterone Antagonists . Mishonga iyi inoshanda nekudzivisa kushanda kwealdosterone hormone (anagonist zvinoreva kushanda pakurwisa). Ndosaka mhando iyi yemishonga ichinziwo 'potassium-sparing diuretics'.
Ndeapi marudzi makuru emishonga ari muchikamu ichi?
Kune mhando dzakasiyana dzemishonga yeAldosterone Antagonist inowanzo nyorwa navanachiremba. Ungave wakaona mazita aya.
| Zita remushonga | Ruzivo rwakakosha |
|---|---|
| Spironolactone (spironolactone) | Uyu ndiwo mushonga wekare uye unonyanya kushandiswa mukirasi iyi. Unouya uri piritsi kana mvura. Unowanzo torwa kamwe chete pazuva. Dzimwe nguva unopihwa pamwe chete neimwe mushonga unobatsira pakubvisa mvura mumuviri, hydrochlorothiazide. |
| Eplerenone (Eplerenone) | Iri piritsi zvakare. Rinorayirwa kutorwa kamwe chete kana kaviri pazuva. Zvinofungidzirwa kuti rine migumisiro mishoma kana tichienzanisa neSpironolactone. |
| Finerenone (Finarenone) | Uyu mushonga mutsva. Unonyanya kukurudzirwa kuvanhu vane chirwere cheitsvo chisingaperi, kunyanya avo vane chirwere cheshuga cherudzi rwechipiri. |
Mushonga uyu unoshanda sei mumuviri?
Zviri nyore kwazvo. Kana ukatora mushonga weAldosterone Antagonist, unoenda wovhara mareceptor anobvumira aldosterone hormone kuti isunge masero mumuviri. Chii chinoitika ipapo?
Homoni inonzi aldosterone haikwanise kuchengetedza munyu nemvura mumuviri. Saka, itsvo dzedu dzinotanga kuburitsa munyu nemvura yakawandisa kuburikidza neweti. Chinhu chakakosha ndechekuti painoburitsa munyu nemvura yakadaro, inodzivirira muviri kubva pakurasikirwa ne potassium inokosha.
Zvichitaurwa zviri nyore, zvinoderedza huwandu hwemvura nemunyu zvinounganidzwa mumuviri zvisina kufanira, uye zvinoderedzawo BP. Izvi zvinoderedzawo mutoro pamwoyo.
Ndezvipi zvirwere zvikuru zvinoshandiswa pakurwisa Aldosterone?
Vanachiremba vanokurudzira rudzi urwu rwemushonga sekurapa kwete chirwere chimwe chete, asi zvirwere zvakasiyana-siyana.
- Kukundikana kwemoyo: Kana moyo usina simba, mvura inoungana mumuviri (edema) uye inokonzera kuzvimba mumakumbo nemumapapu. Mushonga uyu unobatsira kubvisa mvura yakawandisa uye kuderedza kushushikana pamoyo.
- Kukwira Kweropa: Mushonga uyu unobatsira kudzora kukwira kweropa kwakaoma kudzora nemimwe mishonga.
- Chirwere Cheitsvo Chisingaperi: Izvi zvinoshandiswa kurapa chirwere cheitsvo, kunyanya chinouya nechirwere cheshuga.
- Hyperaldosteronism: Ichi chirwere apo muviri unoburitsa hormone yakawandisa inonzi aldosterone. Mushonga uyu unokosha pakurapa chirwere ichi.
- Kuzvimba kunokonzerwa nechirwere chechiropa: Izvi zvinopihwawo kudzora kuchengetwa kwemvura mumuviri nekuda kwechirwere chechiropa.
- Kuderera kwepotassium muropa: Mushonga uyu unopiwawo kune chirwere ichi nekuti unobatsira kuchengetedza huwandu hwepotassium mumuviri.
- Mapundu: Vamwe vanachiremba veganda vanokurudzirawo Spironolactone yepundu nekuti inodzora mashandiro emahormone mamwe.
Mabhenefiti uye migumisiro inogona kuitika yemishonga iyi
Kufanana nemishonga chero ipi zvayo, izvi zvinogona kuva nemabhenefiti pamwe nemamwe matambudziko.
Zvakanakira zvikuru
- Inowedzera hupenyu hwevarwere vane chirwere chemwoyo.
- Vane simba rakawanda rekurovedza muviri uye kuita mabasa ezuva nezuva.
- Zvinoderedza kudiwa kwekuiswa muchipatara.
- Zvinoderedza zvakanyanya njodzi yekufa kamwe kamwe nekuda kwechirwere chemwoyo.
Migumisiro inogona kuitika
Paunenge uchitora mushonga uyu, unogona kuita weti kakawanda kupfuura zvawagara uchiita nekuti unobvisa mvura mumuviri. Izvi zvakajairika. Pamusoro pezvo, zvimwe zvinhu zvinogona kuitika.
- Kukosora
- Dzungu (vertigo)
- Musoro (musoro)
- Manyoka
- Mazinga epotassium akawanda muropa: Ichi ndicho chinhu chikuru chekufunga nezvacho. Njodzi iyi yakanyanya kuwanda kuvanhu vane chirwere cheitsvo. Saka, chiremba anowanzo tarisa huwandu hwepotassium nekuita bvunzo dzeropa.
Migumisiro yakashata yeSpironolactone
Nekuti mushonga weSpironolactone unoshanda pamwe chete nemamwe mahormone mumuviri (androgen neprogesterone), vamwe vanhu vanogona kusangana nezvinotevera:
- Kuwedzera mazamu (Gynecomastia) muvarume nevakadzi.
- Kusashanda zvakanaka pabonde kuvarume (Matambudziko ekusimbisa nhengo dzemurume).
- Kubuda ropa kubva kunhengo yekubereka mushure mekuguma kuenda kumwedzi.
Nekuda kwezvikonzero izvi, vamwe vanhu vangada kushandisa Eplerenone. Asi yeuka kuti chiremba wako chete ndiye anogona kusarudza kuti ndeipi mishonga yakakunakira .
Nguva yekutaura nachiremba wako
Kana ukasangana nematambudziko paunenge uchitora mushonga uyu, usamborega kuutora wega. Taura nachiremba wako nekukasika. Anogona kugadzirisa dose kana kukuchinja kuti uwane mumwe mushonga.
Uyewo, kana zviratidzo zvako zvikasavandudzika mushure mekushandisa mushonga kwemavhiki mashoma, zivisa chiremba wako nezvazvo zvakare.
Uyewo, kana uri kutora mushonga uyu, iva nechokwadi chekubvunza chiremba wako usati wanwa muto wegrapefruit kana kushandisa dzimwe nzira dzemunyu, sezvo mimwe yacho ingave iine potassium.
Mharidzo Yekuenda Nayo Kumba
- Mishonga inodzivirira chirwere cheAldosterone imhando yakakosha yemishonga inorapa zvirwere zvakaita seBP, chirwere chemwoyo, uye chirwere cheitsvo.
- Izvi zvinobvisa munyu wakawandisa nemvura mumuviri uye zvinochengetedza huwandu hwepotassium hunodiwa mumuviri.
- Inwa mushonga wawakanyorerwa sezvawaudzwa nachiremba wako, panguva chaiyo, nemupimo wakakodzera. Usambofa wakatora mishonga miviri panguva imwe chete kuti udzorere mushonga wawakarasikirwa nawo.
- Kana ukasangana nekusagadzikana kana migumisiro yakaipa kubva pamushonga, usazvisarudzire wega uye bvunza chiremba wako nekukasika.
- Zvakakosha zvikuru kuongororwa ropa nguva nenguva, kunyanya kutarisa huwandu hwepotassium mumuviri.
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