Chii chiri kuitika kundangariro yako? Ngatitaure nezvechirwere cheAlzheimer's

Dzimwe nguva unokanganwa zvinhu here? Pane makiyi ako, zita remumwe munhu, kana zvawaida kuita... Kukanganwa kudiki kwakajairika kune wese munhu. Asi kune vamwe vanhu, kukanganwa uku kunogona kuvakanganisa zvakanyanya. Nhasi tichataura nezvechirwere chinokanganisa ndangariro zvakanyanya uye chinokanganisa uropi. Ichi chirwere cheAlzheimer's.

Chii chinonzi chirwere cheAlzheimer?

Zvichitaurwa zviri nyore, chirwere cheAlzheimer's ndechimwe chezvirwere zvikuru zvepfungwa, izvo zvinokonzera kurasikirwa nendangariro uye kudzikira kweruzivo rwepfungwa. Kutaura chokwadi, chirwere chinoparadza tsinga. Izvi zvinoreva kuti nekufamba kwenguva, masero ari muuropi hwedu anokuvara uye anoparadzwa. Pakupedzisira, munhu ane chirwere cheAlzheimer's anogona kurasikirwa nemabasa akakosha europi akadai sekuyeuka uye kugona kutaura.

Fungidzira, vanhu vanosvika mamiriyoni makumi maviri nemana pasi rose vanorwara nechirwere ichi. Munhu mumwe chete pavanhu gumi vane makore anopfuura makumi matanhatu nemashanu anogona kunge aine chirwere ichi. Uyewo, munhu mumwe pavanhu vatatu vane makore anopfuura makumi masere nemashanu anonzi ane chirwere cheAlzheimer.

Kunyange zvazvo paine mishonga yekudzivirira zviratidzo izvi, hapana mushonga wechirwere cheAlzheimer. Kana uchifungidzira kuti iwe kana mumwe munhu ari pedyo newe ane zviratidzo izvi, zvakanaka kuti uone chiremba nekukasika kuti akupe mazano.

Ndezvipi zviratidzo zveAlzheimer's?

Chirwere cheAlzheimer hachibate munhu wese nenzira imwe chete, asi kazhinji, chinogona kukonzera kugona kwako ku:

• Ndangariro
• Kukwanisa kufunga zvine musoro
• Kugona kutaura (mutauro)
• Maitiro uye hunhu
• Kunzwisisa nharaunda yakapoteredza (nzvimbo)

Kazhinji, munhu ane ndangariro dzisingachazivi kana zvimwe zviratidzo zveAlzheimer's angaomerwa nekuona shanduko dziri mupfungwa nemuviri wake. Zviratidzo izvi dzimwe nguva zvinoonekwa zvakanyanya kune vadikanwi vako.

Zviratidzo izvi zvinoramba zvichiwedzera nekufamba kwenguva (kudzikira zvishoma nezvishoma). Kana iwe kana mumwe munhu waunoziva aine zviratidzo zvakaita sedementia, enda kuna chiremba nekukasika.

Kurasikirwa nendangariro

Kurasikirwa nendangariro ndicho chiratidzo chikuru uye chinowanzoonekwa chechirwere cheAlzheimer. Izvi zvinogona kukuomera kurangarira zvinhu zvakaitika munguva pfupi yapfuura (ndangariro pfupi) kana zvinhu zvakaitika kare kare (ndangariro refu).

Ungave nedambudziko rekuyeuka zvinhu izvi:

• Zviso, mazita
• Zvimwe zvinhu
• Kwauri (kunyangwe iri nzvimbo inozivikanwa senge kumba)

Matambudziko ekurangarira anokonzerwa neAlzheimer's akakomba kupfuura zvinhu zvidiki zvatinowanzo kanganwa patinoisa foni yedu kana kuti patinofunga kuti takakiya musuwo here.

Kuomerwa nekufunga zvine musoro

Munhu ane chirwere cheAlzheimer anowanzoita seanovhiringidzika kana kutora nguva yakareba zvisingawanzoitiki kuti aite sarudzo. Izvi zvinogona kukuomera kuita zvinotevera:

• Sarudza zvekuita zvinotevera.
• Bika zvinoenderana neresipi
• Ronga zvirongwa.

Matambudziko ane chekuita nemitauro

Chirwere cheAlzheimer chinogona kukuomera kutaura, kuverenga, kana kunzwisisa mutauro (aphasia). Unogona:

• Anotaura uye haatauri zvakawanda kupfuura kare
• Kana munhu akataura mitauro yakati wandei, anochinja mitauro otaura nenzira yekuvhiringidzika.
• Mutauro unonyanya kutaurwa muhudiki uchachinjwa kuti
• Anoshandisa mazwi asiri iwo

Kuchinja kwemaitiro nehunhu

Unogona kuona shanduko mumanzwiro kana hunhu hwemunhu ane chirwere cheAlzheimer. Vanogona:

• Unogona kuva nepfungwa dzakaipa (kunyangwe nevanhu vawagara uchiziva kwemakore).
• Kuchinja-chinja kwemafungiro kunogona kuitika kakawanda (kunogona kutowedzera hasha kupfuura zvakajairika)
• Unogona kugara uchinetseka, kutya, kana kuona zvinhu zvisipo.
• Ungarasikirwa nechivimbo mauri iwe nevadikanwi vako.

Munhu wese ane mazuva akaipa nenguva dzakaoma. Asi kuchinja kwemanzwiro nehunhu kunokonzerwa neAlzheimer kwakanyanya uye kamwe kamwe kupfuura kuputika kwehasha kana hasha.

Kusaziva zvakawanda nezvenzvimbo yakapoteredza

Ungawana zvakaoma kunzwisisa kuti zvinhu zviri pedyo sei nemuviri wako, kana kuti unganzwa kusakwanisa kudzora muviri wako kupfuura kare. Izvi zvinogona kusanganisira:

• Kurovera fenicha
• Zvakaoma kutora chimwe chinhu.
• Kuomerwa nekufamba zvakanaka kwemaoko sekusunga tambo dzeshangu kana kunyora pakhibhodi

Vanachiremba vanoisa chirwere cheAlzheimer muzvikamu zvakasiyana-siyana. Matanho aya anokuudza kuti uri pedyo sei nechirwere cheAlzheimer, kuti chirwere chako cheAlzheimer chakakomba sei, kana kuti chakurumidza sei kukura.

Ndezvipi zvinokonzera chirwere cheAlzheimer?

Chikonzero chikuru chechirwere cheAlzheimer's kuungana kwemarudzi maviri emapuroteni muuropi zvisina kujairika. Zvikuru, marudzi maviri emapuroteni anonzi amyloid ne tau.

Unoziva, uropi hwedu hune mabhiriyoni emasero etsinga, kana kuti ma neuron . Ma neuron aya ndiwo anotibatsira kufunga, kudzidza, kurangarira, uye kuronga. Puroteni iyoyo ye amyloid yandataura inonamatirana mukati memasero europi uye inobatana kuita ma plaque . Puroteni yeTau inobatana kuita ma tangles . Ma plaque nema tangles aya anodzivirira ma neuron kushanda zvakanaka. Anokanganisa zviratidzo zvemagetsi nemakemikari zvinofamba nepakati pawo.

Kana mapuroteni e-amyloid ne-tau aungana muuropi, anouraya tsinga dzeuropi zvishoma nezvishoma. Izvi ndizvo zvinokonzera kukuvara kusingaperi uye zviratidzo zvechirwere cheAlzheimer. Kufa kwemasero etsinga kunotanga mune chimwe chikamu cheuropi, uye zvishoma nezvishoma kunopararira kune zvimwe zvikamu. Chirwere cheAlzheimer chinowanzotanga muchikamu cheuropi chinodzora ndangariro yedu - hippocampus .

Nyanzvi dzichiri kuferefeta chirwere cheAlzheimer kuti dzione kuti chii chinokonzera kuchengetwa kwemapuroteni aya. Vaongorori vanotenda kuti kuchengetwa kwemapuroteni aya kunotanga kare zviratidzo zvisati zvatanga kuoneka. Zvinogona kunge zvakatanga kare makore gumi usati waona shanduko.

Chirwere cheAlzheimer chinogara nhaka here?

Ehe, chirwere cheAlzheimer chinogona kunge chiri majini.

Kana mumwe wevabereki vako kana vanun'una vako aine chirwere ichi, njodzi yako yekubatwa neAlzheimer's ndeye 10% kusvika 30%. Kana vaviri kana kupfuura vevanun'una vako vaine chirwere ichi, njodzi yako yekubatwa neAlzheimer's yakapetwa katatu kupfuura munhuwo zvake.

Vanhu vane gene reAPOE e4 vari panjodzi yakakura yekubatwa neAlzheimer's. Uyewo, vanhu vane gene iroro vane mukana mukuru wekubata Alzheimer's vachiri vadiki (zera rekutanga). Asi havasi vese vane gene reAPOE e4 vachabatwa neAlzheimer's. Ndicho chinhu chimwe chete chinowedzera njodzi yacho.

Ndezvipi zvinhu zvinokonzera chirwere cheAlzheimer?

Vaongorori havasati vaziva kuti nei vamwe vanhu vachibatwa neAlzheimer's uye vamwe vasingabatwi nayo, asi zvinhu izvi zvinogona kunge zviri zvinhu zvinokonzera njodzi:

• Kuva werudzi rwevatema kana kuti rwechiLatin
• Zvinhu zvinotikanganisa nharaunda (chimwe chinhu chine chekuita nekwaunogara, kwaunoshanda, kana kwaunogara)
• Kuchinja kwemajini
• Kukuvara kwakanyanya mumusoro (Kukuvara kwehuropi kwakakuvara)
• Kusvuta
• Zera rako (chirwere cheAlzheimer chinowanzo bata vanhu vane makore anopfuura 65)
• Hutano hwako hwese

Mamwe matambudziko ehutano anogonawo kuwedzera njodzi yeAlzheimer's. Semuenzaniso:

• Chirwere chemwoyo
• Chirwere cheshuga
• Down syndrome inokonzerwa neTrisomy 21
• Kukwira kweropa
• Kolesteroli yakakwira
• Kufuta

Ndezvipi zvinetso zvinokonzerwa nechirwere cheAlzheimer?

Dambudziko guru rechirwere cheAlzheimer kukuvara kwachinokonzera kuuropi. Izvi zvinogona kukonzera shanduko dzisingaperi mumafungiro ako, kugona kwako kushandisa muviri wako, uye hunhu hwako. Sezvo chirwere ichi chichienderera mberi, unogona kuva nematambudziko akasiyana-siyana. Mamwe acho anogona kuisa hupenyu panjodzi.

Zvinetso zvakadaro zvinogona kuitika:

• Kuora kwehutano hwemuviri
• Utachiona (semuenzaniso, pneumonia kana hutachiona hweganda)
• Kubatwa nepfari
• Kuoma kufema
• Kuoma kumedza

Unogona kurasikirwa nekutonga muviri wako, izvo zvinogona kuwedzera njodzi yako ye:

• Zvironda zvepamubhedha
• Kushaya mvura mumuviri kana kushaya chikafu chinovaka muviri
• Kudonha, kutyoka mapfupa nedzimwe tsaona
• Kutadza kudzora weti uye kusagona kudzora ura
• Kuora kwezino, maburi, nezvimwe zvinetso zvemazino

Chirwere cheAlzheimer chinoonekwa sei?

Vanachiremba vanoshandisa nzira dzakasiyana-siyana kuti vaongorore chirwere cheAlzheimer. Danho rekutanga nderekutaura nezvehutano hwako hwazvino uye nhoroondo yezvekurapa.

Chiremba wako achataura newe nemhuri yako. Vachakubvunza mibvunzo uye vachadzidza nezvehutano hwako uye mabasa ako ezuva nezuva. Kana uchiziva kuti une zvinhu zvinokonzera chirwere cheAlzheimer, udza chiremba wako nezvazvo.

Chiremba wako achabvunza mhuri yako kana vakaona zviratidzo kana shanduko dzausingaone. Vanogona kubvunza nezve:

• Kugona kwako kuita mabasa ako enguva dzose
• Kuchinja kwemanzwiro ako, maitiro ako, uye hunhu hwako
• Mishonga iripo iye zvino
• Nhoroondo yezvekurapa
• Hutano hwese

Chiremba achakuongororwa muviri wose pamwe nekuongororwa kwetsinga. Vachabvisawo zvimwe zvirwere zvinogona kukonzera matambudziko ekurangarira nezvimwe zviratidzo.

Chiremba achashandisawo bvunzo dzakasiyana-siyana, dzakadai se:

• Kuongororwa kweropa
• MRI yeUropi (MRI yeUropi)
• Miedzo yekuziva
• Kuongororwa kweCT
• Kuskena kwePET
• Kuongororwa kwepfungwa nehutano hwepfungwa
• Kuongororwa kweweti

Miedzo iyi inobatsira chiremba wako kutsvaga zviratidzo zvemapuroteni e-amyloid uye kuona kana akakanganisa uropi hwako.

Chiremba wako achashanda newe nemhuri yako kugadzira hurongwa hwekurapa hwakakunakira. Vachakubatsira kuisa zvinangwa zvinokwanisika zvehutano hwako hwenguva pfupi uye hwenguva refu.

Ndeipi mishonga yekurapa chirwere cheAlzheimer?

Chiremba wako anogona kukupa mazano ekurapa kuderedza kufambira mberi kwechirwere chepfungwa. Hapana mushonga wechirwere cheAlzheimer, asi kurapwa kunogona kubatsira kudzora zviratidzo uye kuderedza kufambira mberi kwechirwere.

Kutanga kurapwa nekukurumidza ndiyo nzira yakanakisisa yekuchengetedza hutano hwehuropi hwako muhupenyu hwako hwese. Zvisinei, parizvino hapana mushonga unogona kumisa kana kudzora chirwere cheAlzheimer.

Kune mhando dzakasiyana dzemishonga dzinogona kubatsira kudzora zviratidzo zveAlzheimer's. Chiremba wako achagadzira musanganiswa weiyi kuti ienderane nezvaunoda. Ungangoda:

Zvinodzivisa Cholinesterase

Mishonga iyi inovhara enzyme inokurumidza kukuvara kweuropi kunokonzerwa nechirwere cheAlzheimer. Inogona kugadzirisa mamwe matambudziko ekurangarira uye kuderedza njodzi yekuchinja maitiro. Chiremba wako anogona kunyora mishonga yakaita seiyi:

• Donepezil
• Galantamine
• Rivastigmine

Miedzo yekiriniki

Masayendisiti anogara achitsvaga chirwere cheAlzheimer uye mishonga inogona kutorwa. Bvunza chiremba wako kana paine miedzo yekiriniki inogona kukubatsira. Miedzo yekiriniki bvunzo kana zvidzidzo zvekutsvagisa zvinosanganisira vanhu vanozvipira kutora chikamu muchirwere kana mamiriro ezvinhu akati. Miedzo iyi inogona kukupa mukana wekuyedza mishonga mitsva isati yawanikwa zvakanyanya.

Kana ukaonekwa uine chirwere ichi nekukurumidza, unogona kuwana mikana yakawanda yekupinda mumiedzo yekiriniki.

Lecanemab kana Donanemab

Lecanemab neDonanemab mishonga inopinzwa mutsinga (IV). Imhando mbiri dzemishonga inonzi monoclonal antibodies . Mishonga iyi inogona kubatsira masoja emuviri wako kurwisa nekuparadza mapuroteni eamyloid. Inogona kubatsira kubvisa mamwe maamyloid asati akuvadza uropi, zvichideredza kufambira mberi kwechirwere cheAlzheimer.

Lecanemab inorwisa manyuchi eamyloid asati abatana. Donanemab inorwisa mapuroteni eamyloid akatobatana kuti agadzire maplaque.

Kufanana nedzimwe nzira dzese dzekurapa, mishonga iyi hairapi chirwere cheAlzheimer zvachose, uye haigone kudzorera kukuvara kwatove kwakonzerwa neamyloid.

Vadzivisi veNMDA receptor

Kana uine chirwere cheAlzheimer's, muviri wako unogadzira kemikari yakawandisa inonzi glutamate . Izvi zvinokuvadza masero europi. Vadzivisi veNMDA vanoshanda nekuvhara kana kuzadza maN-methyl-D-aspartate (NMDA) receptors muuropi ayo anosunga kuglutamate. Izvi zvinogona kunonotsa kufambira mberi kwechirwere cheAlzheimer's.

Memantine mushonga unoshandiswa zvakanyanya neNMDA. Chiremba wako anogona kukupa mimwe mishonga zvichienderana nehutano hwako uye danho rechirwere cheAlzheimer.

Mishonga yekurapa zviratidzo

Chiremba wako achakurudzira mishonga kana mamwe marapirwo kuti akubatsire kudzora zviratidzo zvako sezvazvinomuka. Ungangoda:

• Mishonga yekuderedza kushungurudzika: Mishonga iyi inogona kurapa zvinhu zvakaita sekuzvidya mwoyo, kusagadzikana, kuchinja-chinja kwemafungiro, uye kuora mwoyo.
• Mishonga yekurwisa pfungwa/neuroleptics:Mishonga iyi inogona kurapa zvinhu zvakaita se paranoia, kuona zvinhu zvisipo, uye kusagadzikana.
• Mishonga yekudzivirira pfari: Iyi mishonga dzimwe nguva inogonawo kurapa kushanduka-shanduka kwemanzwiro.

Hupenyu hwemunhu hwakaita sei?

Chirwere cheAlzheimer hachibate munhu wese zvakafanana. Vanhu vazhinji vane makore anopfuura 65 vane Alzheimer vanofa mukati memakore mana kusvika masere ekuonekwa vaine chirwere ichi. Asi vamwe vanhu vanorarama kwemakumi emakore, kunyanya kana vakaonekwa vasati vasvitsa makore 65.

Taura nachiremba wako nezvekurarama nechirwere cheAlzheimer (AD). Vanogona kukubatsira kuti uise zvinangwa zvinokwanisika uye zvaunotarisira. Vanogonawo kukubatsira kusarudza kuti riini kutarisirwa kwevanorwara zvikuru kunogona kuva sarudzo yakanaka kwauri nemhuri yako.

Kana uchida rubatsiro, taura nenyanzvi yezveutano hwepfungwa . Zvakajairika kuti vanhu vane chirwere cheAlzheimer nemhuri dzavo vanzwe kushushikana kwakanyanya uye kuzvidya mwoyo, kunyanya mushure mekuonekwa kuti vane chirwere ichi. Manzwiro aya ndeechokwadi uye ndeechokwadi. Nyanzvi yehutano hwepfungwa inogona kukubatsira kunzwisisa mafungiro ako nemanzwiro ako uye kukubatsira kurarama nawo.

Chirwere cheAlzheimer chinogona kudzivirirwa here?

Haugone kuchinja kana kudzora zvimwe zvezvinhu zvinokonzera chirwere cheAlzheimer's, zvakaita sezera rako uye majini ako. Asi unogona kugadzirisa zvimwe zvinhu uye kuderedza njodzi yako. Kuchengetedza hutano hwakanaka kunogona kubatsira kudzivirira uropi hwako kubva pakudzikira kwepfungwa. Unogona kuedza zvinhu izvi:

• Tevedzera kudya kwakanaka: Kudya kudya kunovaka muviri kwakasiyana-siyana kunogona kubatsira kuchengetedza pfungwa dzako nehutano hwako hwese zviri muchimiro chakanaka. Chiremba wako anogona kukurudzira chirongwa chekudya, senge kudya kweMediterranean kana kudya kweDASH .
• Wana maekisesaizi akakwana: Maekisesaizi uye maekisesaizi emuviri zvinowedzera kuyerera kweropa neokisijeni kuenda kuuropi. Izvi zvinogona kuvandudza hutano hwemasero europi hwako. Haufanire kunge uri mutambi mukuru kuti urambe uchishingaira. Kufamba-famba, kurima bindu, kuchovha bhasikoro, kana chero chinhu chinokufadza chinoita kuti muviri wako ushande zvakanaka inzira dzakanaka dzekugara uchishingaira.
• Ramba wakasimba mupfungwa: Tamba mitambo yebhodhi, verenga mabhuku, ita mapuzzle emashoko akasiyana-siyana, tamba chiridzwa chemimhanzi, kana kuti tamba zvimwe zvinhu zvinokuvaraidza zvinoedza pfungwa dzako kuti dzidzidze zvinhu zvitsva uye dzizvishandise.
• Gara uchishamwaridzana nevanhu: Taura nevadikanwi vako kana vanhu vari munharaunda yako nguva dzose. Kupinda mumapoka ezviitiko zvakaita semisangano yechitendero, makirasi ekurovedza muviri, makirabhu emabhuku, kana basa rekuzvipira munharaunda zvinogona kubatsira kuchengetedza pfungwa dzako dzichishanda.

Kana mumwe munhu mumhuri mako aine chirwere cheAlzheimer's uye uchinetseka nacho, taura nachiremba wako nezvekuongororwa kwemajini. Vanogona kutarisa majini kana shanduko dzemajini dzinogona kuwedzera njodzi yako yekubatwa neAlzheimer's.

Unofanira kuona chiremba rini?

Kana iwe kana mumwe munhu waunoda ari kunetseka nekuyeuka kana kufunga, enda kuna chiremba. Vanogona kuona kana matambudziko acho ari kukonzerwa neAlzheimer's kana chimwe chirwere.

Kana wangoonekwa uine chirwere cheAlzheimer (AD), unofanira kuona chiremba wako kuti agare achiongororwa. Chiremba wako achaongorora kufambira mberi kwechirwere uye achagadzirisa marapirwo ako sezvinodiwa.

Unogonawo kubvunza chiremba wako mimwe mibvunzo yakaita seiyi:

• Ndezvipi zviratidzo kana shanduko zvatinofanira kutarisa nemhuri yangu?
• Pane nzira here yekufanotaura kuti chirwere cheAlzheimer chichakurumidza sei kukura?
• Ndeipi nzira yekurapa yakandinakira?
• Ndinokodzera here kuongororwa kwekiriniki?

Chirwere cheAlzheimer (AD) chirwere chinotyisa zvechokwadi. Dzimwe nguva zvinogona kunzwa sekunge nguva yamira, kana kuti zvinogona kunzwa sekunge zviri kufamba nekukurumidza. Hapana nzira yakaipa yekurarama nechirwere chakaita sechirwere cheAlzheimer.

Chekupedzisira, chinhu chinonyanya kukosha

Chirwere cheAlzheimer chirwere chakakomba. Asi yeuka, hausi wega. Ungave uine Alzheimer's kana kuti uri kutarisira mumwe munhu ane Alzheimer's, vanachiremba vako vanogara varipo kuti vakubatsire. Vanogona kukubatsira kupa mazano ekurapwa uye miedzo yekiriniki, kupindura mibvunzo yako, kukubatanidza nezvinhu zvekushandisa, uye kukubatsira kunzwisisa zvaunotarisira. Zvakakosha kuziva zviratidzo nekukurumidza uye kutsvaga rubatsiro rwechiremba. Zvakare, rutsigiro rwemhuri neshamwari runokosha parwendo urwu. Usakanganwa kutarisira hutano hwako hwepfungwa, zvakare.

Alzheimer 's, Alzheimer's, Dementia, Kurasikirwa Nendangariro, Hutano Hwepfungwa, Kukwegura, Chirwere Chetsinga