Unoziva here nezve APOE Gene Test? Ngatitaurei nezvazvo!

Ungave wakambonzwa nezvebvunzo yejini ye'APOE' kune imwe nzvimbo, kana kuti ungave usina. Uku kuongorora majini. Kunoongorora rudzi rwejini ('genotype') yawakadana kuti apolipoprotein E (`apolipoprotein E (APOE)`). Izvi zvakakosha nekuti kana uine mamwe majini e'APOE` akasiyana, unogona kunge uri panjodzi huru yekubatwa nechirwere cheAlzheimer. Asi usatye paunonzwa izvi. Tichataura nezveizvi zvese zvakajeka uye zviri nyore munyaya ino.

Chii chinonzi `APOE` gene? Tine rimwe gene here mumiviri yedu?

Ehe, jini re'APOE' ijini rinopa mirairo kumasero edu. Kutaura chokwadi, jini iri rinoudza masero edu kuti agadzire puroteni inonzi 'apolipoprotein E'. Puroteni iyi inokosha zvikuru nekuti inosanganiswa nemafuta ('lipids'), akadai secholesterol, mumiviri yedu kuti igadzire zvidimbu zve'lipoprotein'. Izvi zvikamu zvemapoprotein ndizvo zvinotakura cholesterol nemamwe mafuta kuburikidza netsinga dzedu dzeropa. Zvichitaurwa zviri nyore, zvinoshanda semota inotakura cholesterol kutenderera miviri yedu.

Kune mhando nhatu huru, kana kuti ma alleles, eAPOE gene:

• `APOE-e2 (APOE2)`
• `APOE-e3 (APOE3)`
• `APOE-e4 (APOE4)`

Tose tinogara nhaka makopi maviri ejini re'APOE'. Rimwe kubva kuna amai vedu, rimwe kubva kuna baba vedu. Saka unogona kuva nemusanganiswa wechero ma'alleles' maviri patatu ataurwa pamusoro apa. Semuenzaniso, unogona kuva ne'APOE-e3/e3`, 'APOE-e3/e4`, 'APOE-e2/e4`, nezvimwewo.

Zvichienderana nekusanganiswa kwemajini aunotora nhaka, nzira iyo muviri wako unotakura nayo cholesterol nemamwe mafuta muropa rako inogona kukanganiswa, izvo zvinogona kuwedzera kana kuderedza njodzi yako yekurwara nezvimwe zvirwere.

Ndeipi mhando yemajini eAPOE inobatanidzwa nechirwere cheAlzheimer?

Heino chimwe chinhu chekurangarira : Hapana jini rakawanikwa richikonzera chirwere cheAlzheimer zvakananga. Kureva kuti, hapana chinhu chakadai sekuti "kana uine jini iri, zvechokwadi uchabatwa neAlzheimer's."

Zvisinei, tsvakiridzo yakawana kuti kana uine kopi imwe chete yemhando yegene `APOE-e4 (APOE4)`, njodzi yako yekubatwa nechirwere cheAlzheimer inogona kuwedzera zvishoma. Izvi zvinonyanya kubata vanhu vane makore anopfuura 65, chinonzi `chirwere cheAlzheimer chanonoka`. Kashoma kuti vanhu vari pasi pemakore 65 vabatwe nechirwere cheAlzheimer, chinonzi `chirwere cheAlzheimer chepakutanga`. Chirwere cheAlzheimer chirwere chinokonzera kurasikirwa nendangariro zvishoma nezvishoma, kana kuti dementia.

Kune rumwe rutivi, zvimwe zvidzidzo zvakaratidza kuti kuva nerudzi rwemajini rwe`APOE-e2 (APOE2)` kunopa dziviriro kubva kuchirwere cheAlzheimer. Kunyangwe kana munhu ane rudzi urwu rwemajini akava nechirwere cheAlzheimer, chinowanzoitika gare gare muhupenyu kupfuura munhu ane rudzi rwe`APOE-e4 (APOE4)`.

Zvakakosha: Kuwedzera njodzi hazvirevi kuti uchava nechirwere ichi zvechokwadi. Zvinongoreva kuti une mukana wekuwana chirwere ichi kupfuura mamwe. Majini ndiwo chinhu chimwe chete chinokanganisa njodzi. Zvimwe zvinhu zvakawanda zvinogona kukanganisa izvi.

Ungaongorora sei kana uine jini rekuti 'APOE4'?

Kuongororwa kwemajini eAPOE ibvunzo yekuzvidira. Vanhu vazhinji vanowana ruzivo nezvejini reAPOE kuburikidza nekuongororwa kwemajini kumba. Kana, kana uchida kuziva njodzi yako yekubatwa nechirwere cheAlzheimer, unogona kubvunza chiremba wako nezvazvo. Ungangoda kufunga nezvekuongororwa, kunyanya kana mumwe munhu mumhuri yako, sevabereki vako chaivo kana vanun'una vako, aine chirwere cheAlzheimer (nhoroondo yemhuri).

Kana uchitova nechirwere cheAlzheimer, chiremba anogona dzimwe nguva kukurudzira bvunzo iyi kuti akubatsire kuona kuti ndeapi marapirwo akakunakira.

Kuongororwa kwemajini eAPOE chishandiso chakakoshawo kune vaongorori, vari kuenzanisa mhedzisiro yebvunzo idzi nezvidzidzo zvakasiyana-siyana zvekufungidzira uropi kuti vaedze kuwana mishonga mitsva uye inoshanda yechirwere cheAlzheimer.

Chii chinoitika panguva yekuongororwa kwemajini kweAPOE? Chii chandinofanira kutarisira?

Zvinhu zvinotevera zvinowanzoitika panguva yekuongororwa kwemajini kweAPOE:

1. Kutora sampuro: Chiremba kana mushandi wehutano akadzidziswa achatora sampuro ye'DNA' kubva kwauri. Izvi zvinogona kuitwa nekutora ropa diki ('kuongororwa ropa') kana nekutora masero mashoma kubva mukati memuromo wako ('kuputirwa padama'). Iyi inzira isingarwadzi uye iri nyore .

2. Kutumira kurabhoritari: Muenzaniso we'DNA' wakawanikwa unotumirwa kurabhoritari yakakosha.

3. Kuongororwa: Rabhoritari inoongorora DNA sampuro uye inowana kuti magene ako eAPOE akasiyana sei.

4. Kukurukura nezvemhedzisiro: Kana zvabuda, chiremba wako kana mupi wezano wezvemajini achataura newe nezvemhedzisiro yacho uye zvazvinoreva.

Kana uri kushandisa bvunzo yekuongorora njodzi kumba, unofanira kuverenga mirairo inouya nekit yekuyedza nokungwarira woitevedzera nemazvo. Kit dzemakambani akasiyana dzinogona kunge dziine nzira dzakasiyana zvishoma. Zvakanaka kukurukura zvabuda nachiremba wako mushure mekunge wazviwana.

Zvinorevei mhedzisiro yebvunzo yeAPOE?

Mhedzisiro yekuongororwa kwemajini eAPOE inokuudza kuti ndeapi marudzi eAPOE alleles auri nawo. Semuenzaniso, mhedzisiro yako ichakuudza kana uine APOE-e3/e3, APOE-e3/e4, kana APOE-e2/e3.

Mhedzisiro yemakiti ekuyedza kumba inogona kusiyana zvishoma nemhedzisiro yaunowana kubva kuna chiremba. Kana uine chero mibvunzo, unogona kubvunza kambani yakaita bvunzo.

Chiremba kana mupi wezano wezvemajini achakutsanangurira zvinorehwa nemhedzisiro iyi. Semuenzaniso, kana mhedzisiro yacho ichiratidza kuti uri panjodzi yakakura yekubatwa nechirwere cheAlzheimer, chiremba wako anogona kukupa mazano ekubatsira kuchengetedza hutano hwako hwese . Semuenzaniso:

• Kuita maekisesaizi kana maekisesaizi nguva dzose .
• Wana hope dzakakwana dzemuviri wako.
• Kugara uchishamwaridzana nevamwe nekupedza nguva neshamwari nemhuri.
• Kunetsa pfungwa dzako nezvinhu zvakaita sekupedza mapuzzle, kuverenga mabhuku, kana kudzidza chimwe chinhu chitsva.

Pamusoro peizvi, chiremba wako anogonawo kukupa mamwe mazano anoenderana nehutano hwako.

Zvinorevei kuti `APOE4` yakanaka?

`APOE4` yakanaka zvinoreva kuti une kopi imwe chete yejini re`APOE-e4 (APOE4)` mu`DNA` yako. Izvi zvinoreva kuti majini ako anogona kuva `APOE-e3/e4`, `APOE-e4/e4`, kana `APOE-e2/e4`.

Ndeipi mukana wekuti munhu awane chirwere cheAlzheimer kana aine jini rekuti 'APOE4'?

Zvichienderana nehuwandu hwevanhu, pakati pe15% ne25% yevanhu vose vane kopi imwe chete yejini re`APOE-e4 (APOE4)`. Zvakare, pakati pe2% ne5% vane makopi ese ari maviri ejini iri (`APOE-e4/e4`). Tatokurukura kuti kuva nekopi imwe chete yejini re`APOE4` kunowedzera njodzi yekubatwa nechirwere cheAlzheimer's.

Zvisinei, kuva nejini iri hazvirevi kuti uchava nechirwere cheAlzheimer . Yeuka, bvunzo yemajini haisi bvunzo yekuongorora. Inongoongorora njodzi yako chete. Haisimbisi kana kubvisa chirwere ichi. Mupi wezano wemajini anogona kukubatsira kunzwisisa zvinorehwa nemhedzisiro iyi uye zvaunofanira kuita zvinotevera.

Zvinotora nguva yakareba sei kuti uwane mhedzisiro yeAPOE genetic test?

Zvinowanzotora mazuva mashoma kuti mhedzisiro yekuongororwa kwemajini kweAPOE kwakaitwa nachiremba iwanikwe. Zvisinei, nguva ino inogona kusiyana zvishoma zvichienderana nechipatara kana nzvimbo yaunowana bvunzo. Chiremba wako achakwanisa kukupa ruzivo rwakanyatsojeka.

Bvunzo dzekumba dzinogona kutora chero nguva kubva pamavhiki mashoma kusvika kumwedzi mishoma kuti dziwane mhinduro, zvichienderana nekambani.

Tinofanirawo kufunga nezvepfungwa dzinokanganiswa neruzivo rwatakawana kubva mubvunzo iyi.

Kana tichitaura nezvezvirwere zvakaoma seAlzheimer's, zvinogona kunyaradza kuva netsananguro, mhinduro. Kuongororwa kwemajini kwe'APOE' kunogona kupa tsananguro yekuti sei uchinyanya kubatwa neAlzheimer's.

Zvisinei, mhedzisiro yekuongororwa kwemajini inogona kukukanganisa nenzira dzakasiyana. Ruzivo rwaunowana runogona kukonzera kusuruvara, kuzvidya mwoyo, kutya, kana hasha. Mune zvimwe zviitiko, mhedzisiro yacho ingasava mhinduro yawaitarisira.

Chiremba anogona kukubatsira kuburikidza nechiitiko ichi. Vanogona kutsanangura zvabuda muongororo yako uye kukupa ruzivo rwese rwaunoda kuti unzwisise zviri kuitika. Pasinei nekuti majini ako akaita sei, kune matanho ekudzivirira aunogona kutora kuderedza njodzi yako yekubatwa nechirwere cheAlzheimer. Chiremba wako ndiye munhu akanakisa wekukutungamira mukuronga matanho ako anotevera.

Chekupedzisira, zvinhu zvakakosha zvekurangarira (Mharidzo Yekuenda Kumba)

Saka, ndinovimba wadzidza chimwe chinhu chakakosha kubva pane zvatakurukura nezve `APOE` genetic test. Chekupedzisira, yeuka pfungwa idzi:

• Kuongororwa kwemajini eAPOE kunongokuudza njodzi yako yezvirwere zvakasiyana-siyana, zvakaita sechirwere cheAlzheimer, asi hazvirevi kuti uchazobatwa nechirwere ichi zvechokwadi .
• Iyi haisi bvunzo yekuongorora chirwere .
• Kunyangwe kuva nerudzi rwemajini rwe`APOE-e4 (APOE4)` kuchiwedzera njodzi, kurarama nemararamiro ane hutano uye kutevedzera mazano ekurapa kunogona kubatsira kudzora njodzi iyoyo.
• Zvakakosha kutsvaga rubatsiro kubva kuna chiremba kana mupi wezano wezvemajini kuti unzwisise zvabuda muongororo uye kugadzirisa migumisiro yepfungwa inokonzerwa nazvo.
• Hazvina mhosva kuti majini ako akaita sei, kuchengetedza mararamiro ane hutano (kudya zvakanaka, kurovedza muviri, kurara zvakakwana, kugara zvakanaka kwepfungwa) kunobatsira pahutano hwese.

Tinovimba kuti ruzivo urwu ruchakubatsira. Kana muine mimwe mibvunzo, ndapota musazeza kutaura nachiremba.

Kuongororwa kwemajini kweAPOE , chirwere cheAlzheimer, APOE4, njodzi yemajini, dementia, mazano emajini, ruzivo rwehutano