Unoziva here nezvechirwere ichi chisingawanzoitiki chinonzi Carney Complex?

Ruvara rweganda rako rwakachinja kamwe kamwe here, kana kuti wakaona mavara kana mavanga asingazivikanwe here? Kana kuti wakaona mapundu madiki pamuviri wako here? Ungave uchinetseka zvishoma. Dzimwe nguva hatinyatsotarisiri zviratidzo izvi. Zvisinei, shure kwezviratidzo izvi, panogona kunge paine chirwere chisingawanzoitiki chinonzi Carney Complex chinoda kutarisirwa kwakakosha. Usazvidya moyo, tichataura nezvazvo zviri nyore uye nenzira yaunogona kunzwisisa.

Chii chaizvo chinonzi Carney Complex?

Zvichitaurwa zviri nyore, Carney Complex chirwere chinokanganisa ruvara rweganda redu uye chinoita kuti mabundu asiri ekenza (asina njodzi), kureva kuti, mabundu asingawanzo kuva nengozi, aumbe mumatishu emuviri uye mumagland eendocrine. Izvi zvinowanzokonzerwa nechikonzero chemajini. Kureva kuti, zvinokonzerwa nekuchinja (mutation) mujini rinogarwa nhaka kubva kuvabereki kuenda kuvana.

Pane mamwe mazita here eizvi?

Ehe, Carney Complex inozivikanwawo nemamwe mazita akati wandei. Chiremba wako anogona kushandisa rimwe remazita aya:

• Carney syndrome
• NAME syndrome - Mabhii ekuti NAME anomiririra nevi (nzvimbo dzakaita semavanga ekuzvarwa), atrial myxoma (rudzi rwebundu rinoitika mumoyo), myxoid neurofibromas (rudzi rwebundu rine chekuita netsinga), uye ephelides (nzvimbo).
• Chirwere cheMBWA - Izvi zvinomirirawo lentigines (mavara ebrown), atrial myxoma, uye blue nevi (mavara ekuzvarwa ebhuruu).

Ndiani anowana chirwere cheCarney? Chinowanikwa kakawanda sei?

Carney Complex chirwere chinoitika kuvanhu vanozvarwa vaine majini akasiyana. Zvisinei, vanhu vazhinji vangasaziva kuti vane chirwere ichi kusvika zviratidzo zvatanga. Kunyangwe zviratidzo izvi zvichigona kuonekwa chero nguva muhudiki, vanhu vazhinji vanoonekwa navanachiremba vane makore ari pakati pemakumi maviri.

Nezvekuti izvi zvakajairika sei, Carney Complex chirwere chisingawanzoitiki . Ingofungai, kune vanhu vashoma pane mazana manomwe nemakumi mashanu pasi rose vakaonekwa vaine chirwere ichi. Saka hapana chikonzero chekuvhunduka nacho, asi zvakakosha kuziva.

Sei Carney Complex iyi ichikura? Chikonzero chacho ndechei?

Carney Complex chirwere chinokonzerwa nemajini.. Dambudziko iri rinonyanya kukonzerwa nekuchinja kwemajini kunonzi (PRKAR1A gene). DNA iri mujini iri inodzidzisa muviri wedu maitiro ekugadzira enzyme inodzora puroteni yakati. Funga nezvejini iri senzvimbo huru yekudzora yefekitori. Kana paine kuchinja kwemajini aya (PRKAR1A gene), puroteni ine chekuita neenzyme iyoyo haigone kudzorwa nemazvo. Ipapo masero anotanga kukura zvisingadzoreki uye zvakawandisa. Ndizvo zvinotanga kuumbwa zvinhu zvakaita semamota.

Kazhinji, inenge 70% yeCarney Complex inokonzerwa nemwana anogara nhaka iyi shanduko yemajini kubva kune mumwe wevabereki vake. Zvisinei, kune vamwe vanhu, chirwere ichi chinokonzerwa nekuchinja kwemajini kuchangobva kuitika, zvichireva kuti hachigamuchirwi kubva kumubereki.

Kuchinja kwemajini uku ndiko chete kunokonzera here?

Havasi vese vane Carney Complex vanogona kunge vaine majini akachinja. Vaongorori vanotenda kuti chirwere ichi chinogonawo kukonzerwa nekuchinja kwechikamu chechromosome (morekuru ine majini). Zvisinei, tsvakiridzo pamusoro peizvi ichiri kuenderera mberi.

Ndezvipi zviratidzo zvikuru zveCarney Complex?

Kana uine Carney syndrome, unogona kuona shanduko mukuchinja kweruvara rweganda rako.

• Mavanga nenyemba: Izvi zvinogona kuonekwa chero kupi pamuviri, asi zvinonyanya kuonekwa pa:
• Maziso akatenderedza
• Miromo yakasungwa.
• Kutenderedza nzvimbo yesikarudzi. Mavara aya anogona kutaridzika semadotsi madiki ebrown, ruvara rwebhinzi yekofi.
• Nevi yebhuruu: Dzimwe nguva mavara ekuzvarwa ebhuruu kana matema anogona kuoneka paganda.

Ndezvipi zvimwe zviratidzo kunze kwekuchinja kweganda?

Vamwe vanhu vane Carney Complex vanogona kuwana cardiac myxomas. Izvi zvinogona kuva nengozi zvikuru uye zvinoda kutarisirwa kwakakosha. Pamusoro pezvo, bundu rinogona kukura mune dzimwe nzvimbo dzakawanda. Semuenzaniso:

• Mapfupa
• Mazamu
• Nhengo dzepabonde
• Mahormone anogadzira mahormone (endocrine system) - semuenzaniso, thyroid gland uye adrenal glands.
• Sisitimu yetsinga
• Ganda
• Chikamu chepamusoro chehuro (oropharynx)

Chinhu chakakosha ndechekuti mapundu mazhinji anokura nenzira iyi haasi ekenza (asina kuipa). Izvi zvinoreva kuti haakuvadzi zvakanyanya. Zvisinei, mune dzimwe nguva, mamwe mapundu anogona kuita kenza (anokonzera kenza) . Ndosaka zvichikosha kuti ugare uchiongororwa nachiremba.

Ichi chirwere chinotapukira here?

Kwete, kwete zvachose. Carney Complex haisi chirwere chinotapuriranwa . Haugone kuchibata nemunhu ane chirwere ichi.

Chirwere ichi chinoongororwa sei nemazvo? (Kuongororwa)

Kana iwe kana chiremba wako muchifungidzira kuti une Carney Complex, chiremba wenyu achatanga aita ongororo yemuviri . Vachabvunzawo nezvenhoroondo yemhuri yenyu. Kuongororwa kwemajini kunogona kudiwa kuti kusimbiswe chirwere chacho.

Ndezvipi zviedzo zvinoshandiswa pakuongorora chirwere?

Zvichienderana nezviratidzo zvauri kuona iwe kana mwana wako, vanachiremba vanogona kukurudzira bvunzo dzakasiyana-siyana. Zvimwe zvacho zvinosanganisira:

• Echocardiogram: Iyi i scan yekutarisa mashandiro emoyo. Izvi zvakakosha zvikuru pakuongorora bundu remoyo.
• Kuongororwa kweropa neweti: Kuongororwa uku kunoitwa kuti paonekwe huwandu hwemahormone.
• Miedzo yakasiyana-siyana yekufungidzira: Miedzo yakaita se ultrasound, CT scan, MRI, uye X-ray inoshandiswa kuona kana paine bundu mumuviri.
• Kuongororwa kweganda: Kana paine gomarara kana kukura kweganda, ganda rinotorwa roongororwa nemaikorosikopu.
• Kuongororwa kwemajini: Izvi zvakakosha kusimbisa kana paine shanduko mu (jini rePRKAR1A).

Ndezvipi zvirongwa zvekurapa Carney Complex?

Chiremba anokurudzira kurapwa zvichienderana nezviratidzo zvaunazvo iwe kana mwana wako.

• Kuvhiyiwa kwemoyo pachena kubvisa bundu remwoyo: Bundu remoyo rinogona kuva nengozi uye rinoda kuvhiyiwa kuti ribviswe.
• Kuvhiyiwa kubvisa bundu paganda kana mamwe matumbu: Bundu paganda kana bundu pamasero ehomoni rinobviswawo nekuvhiyiwa, kana zvichidikanwa.

Chiremba wako achataura newe nezvenzira dzekurapa dzakakunakira.

Izvi zvinogona kurapwa zvachose here?

Carney Complex chirwere chinogara kwenguva refu . Izvi zvinoreva kuti hachigone kurapwa zvizere. Asi usazvidya mwoyo, vanachiremba vanogona kukubatsira kudzora zviratidzo zvako uye kurarama hupenyu hune hutano. Kuti izvi zviitike, kurapwa kwakakodzera uye kugara uchitarisirwa nachiremba zvakakosha zvikuru.

Pane nzira dzekuderedza njodzi yekubatwa nechirwere ichi here?

Hapana nzira yekudzivirira Carney Complex nekuti chirwere chemajini. Zvisinei, kana uine pamuviri, unogona kuongororwa genetic amniocentesis kuti uone kana mwana wako aine chero chirwere chemajini.

Ndingaziva sei kana ndiri panjodzi yekubatwa nechirwere ichi?

Kana paine munhu mumhuri yako - kunyanya vabereki vako - ane Carney Complex, zvakakosha kutaura nachiremba wako nezvazvo kuitira kuti bvunzo dzinodiwa dziitwe.

Kana ndine Carney Complex, chii chandinofanira kutarisira?

Kana uine Carney Complex, unofanira kuzivisa chiremba wako nekukasika kana ukaona zviratidzo zvitsva. Chiremba wako anogonawo kukurudzira kuongororwa nguva nenguva kuti utarise huwandu hwemahormone ako uye hutano hwako hwese. Semuenzaniso:

• Echocardiogram yegore negore .
• Kuongororwa kweropa.
• Kuongororwa kwehurongwa hwe endocrine.
• Kuongororwa kweganda.
• Kuvarume, kuongororwa kwemachende kana kuti ultrasound.

Ndichararama kwenguva yakareba sei nechirwere ichi?

Sezvambotaurwa, Carney Complex chirwere chinogara kwenguva refu . Chiremba wako achava mubatsiri akakosha mukugadzirisa zviratidzo zvako uye kugara uine hutano hwakanaka.

Chii chingataurwa nezvenguva yekurarama kwevanhu vane chirwere ichi?

Vanhu vane Carney Complex vanogona kurarama hupenyu hwakajairwa , asi chinonyanya kukosha ndechekuongororwa nachiremba nguva dzose uye kutevedzera mazano echiremba.

Matumbu anogona kudzoka here mushure mekurapwa?

Ehe, zvinosuwisa kuti dzimwe nguva bundu rinogona kudzoka mushure mekurapwa. Ndosaka zvichikosha kuti ugare uchiongororwa nachiremba.

Carney Complex igomarara here?

Kazhinji, mapundu anokura muCarney Complex haana njodzi . Izvi zvinoreva kuti haakonzeri kukuvara kwakanyanya. Zvisinei, nekufamba kwenguva, mamwe mapundu anogona kuva kenza/anokuvadza . Saka, zvakakosha kuudza chiremba wako nezvezviratidzo zvitsva uye kuti aedzwe bvunzo dzese dzinodiwa.

Ndezvipi zvinetso zvinogona kuitika neCarney Complex?

Ehe, chirwere ichi chinogona kukonzera mamwe matambudziko.

• Kana uine bundu mugland rako repituitary (chikamu che endocrine system), rinogona kukanganisa kugadzirwa kwehomoni yekukura mumuviri wako. Kana homoni yekukura yakawandisa ikagadzirwa, zvinotevera zvinogona kuitika:
• Arthritis
• Kuchinja kwechimiro chechiso
• Kukura kusina kujairika kwemaoko netsoka (acromegaly)
• Kana bundu rikakura mune mamwe ma endocrine glands, rinogona kutungamira kumamiriro ezvinhu akadai se:
• Chirwere cheCushing
• Gomarara reSertoli rinoita kuti masero makuru awedzere kukora (rudzi rwegomarara rinokura mumachende)
• Chirwere chepakutanga che adrenocortical chine pigmented nodular ( bundu re adrenal glands)
• Schwannomas(Rudzi rwebundu rinokura patsinga)
• Mapundu e thyroid ( mapundu ari mu thyroid gland)

Kunyange zvazvo izvi zvinganzwika sekunge zvakaoma, zvese zvine chekuita nehurongwa hwemahormone. Ndosaka zvichikurudzirwa kuti ugare uchiongororwa huwandu hwemahormone ako.

Munhu ane Carney Complex anofanira kuenda kuna chiremba rini?

Tevedzera mirairo yachiremba wako nemazvo. Usapotsa bvunzo dzakarongwa uye nguva yekutevera chero chikonzero chipi zvacho . Kana ukaona zviratidzo zvitsva, zivisa chiremba wako nekukasika.

Izvi zvingakonzera emergency here?

Ehe, dzimwe nguva njodzi dzinogona kuitika. Mamota, kunyanya ayo anoumba mumoyo, anogona kuvharira kufamba kweropa. Izvi zvinogona kutungamira kuzvirwere zvakakomba zvakaita sestroke , kutadza kushanda kwemoyo , kana kumira kwemoyo kamwe kamwe . Saka, tsvaga rubatsiro rwechiremba nekukasika kana uine chimwe chezviratidzo izvi:

• Kuchinja kwemoyo wako
• Kukosora kana kufemera
• Kuneta kakawanda
• Kushaya mweya
• Kuzvimba mumuviri - kunyanya mudumbu, muzvitsitsinho, kana mutsoka.

Mharidzo Yekupedzisira Yekuenda Kumba

Carney Complex chirwere chisingawanzoitiki chemajini chinogona kukonzera kuchinja kweruvara rweganda uye bundu risina njodzi munzvimbo dzakasiyana dzemuviri, kunyanya pamoyo nepa endocrine system. Kana bundu iri rikaita matambudziko, vanachiremba vanogona kuribvisa nekuvhiya.

Kunyangwe ichi chiri chirwere chehupenyu hwese, nekutevera mazano akakodzera ekurapa uye kuongororwa nguva dzose, iwe kana mwana wako munogona kurarama hupenyu hune hutano. Saka, zvakakosha kuteerera zvinotaurwa nachiremba wako uye kuita zvinoenderana nazvo. Usazvidya mwoyo, hausi wega, uye vanachiremba varipo kuti vakubatsire.

Carney Complex, mavanga eganda, kuchinja kweruvara rweganda, bundu remuviri, zvirwere zvemajini, matambudziko emahormone, chirwere chemwoyo, jini rePRKAR1A