Mwana wako mudiki anonzwa fivha, maronda emuromo, kana kurwadziwa pahuro mazuva akafanana mwedzi wega wega here? Chirwere chimwe chete chinopera here, chozodzoka mavhiki maviri kana matatu gare gare? Ungave uchifunga kuti, "Simba remuviri wemwana wangu harina simba." Ehe, izvozvo zvingave zvechokwadi. Asi chikonzero chechirwere ichi chinogona kunge chiri chirwere chisingawanzoitiki. Nhasi, tiri kutaura nezvechimwe chezvirwere zvakadaro, cyclic neutropenia.
Zvichitaurwa zviri nyore, chii chinonzi cyclic neutropenia?
Kuti tinzwisise izvi, tinofanira kutanga taziva nezvemusoja ari muropa redu. Zita remusoja iyeye rinonzi neutrophil . Iyi neutrophil rudzi rwemasero machena eropa anotidzivirira kubva kuzvirwere nekurwisa utachiona, kunyanya mabhakitiriya, anopinda mumiviri yedu. Zvakafanana neuto riri mukati memiviri yedu.
Neutropenia inguva apo huwandu hwemasoja e-neutrophil muropa hunodzikira pasi pemazinga akajairwa. Kungofanana neuto rinova risina simba kana masoja aro ari mashoma, kana ma-neutrophil ari mashoma, masoja emuviri wedu anova asina simba uye tinotanga kuwana hutachiona zviri nyore.
Zvino ngatitarisei zvinoreva izwi rekuti cyclic . Cyclic zvinoreva "cyclical." Izvi zvinoreva kuti huwandu hwe neutrophil hahuwanzova hwakaderera. Hunokwira nekudzika pane imwe nguva, mudenderedzwa. Kutaura chokwadi, kazhinji mavhiki matatu ega ega (anenge mazuva makumi maviri nerimwe) , huwandu hwe neutrophil hunodzikira zvakanyanya kwemazuva matatu kusvika mashanu. Wobva wadzokera kune zvakajairika, wozodzikira zvakare kwemavhiki matatu anotevera. Kutenderera uku kunoitika nenzira inofungidzirwa zvikuru.
Zvichitaurwa zviri nyore, cyclic neutropenia chirwere umo huwandu hwemasero e-neutrophil, anodzivirira miviri yedu kubva kuzvirwere, hunoderera zvichienderana nekufamba kwezuva nezuva, zvichiwedzera njodzi yekutapukirwa.
Dambudziko iri hariwanzoitiki. Vaongorori vanoti munhu mumwe chete pavanhu miriyoni panyika ane chirwere ichi.
Ndezvipi zviratidzo zvechirwere ichi?
Chinhu chakakosha pachirwere ichi ndechekuti zviratidzo zvinoonekwa zvichienderana nekudzikira kwemazinga e-neutrophil. Kureva kuti, zviratidzo izvi zvinoonekwa mukati memazuva matatu kusvika mana kubva pakudzikira kwema-neutrophil, uye kana mazinga e-neutrophil adzoka paakajairika, zviratidzo zvinopera.
| Chiratidzo | Tsananguro |
|---|---|
| Fivha uye kuneta | Kana ma neutrophils ari mashoma, chiratidzo chekutanga chehutachiona mumuviri chingave fivha. Pamwe chete neizvi, muviri unogona kunzwa usina hupenyu. |
| Maronda emuromo uye pahuro panorwadza | Ichi chiratidzo chinowanzoitika. Chinogona kukonzera maronda anorwadza mumuromo nemumazino. Chinogonawo kukonzera kurwadziwa pahuro. |
| Chirwere cheperiodontal | Kubuda ropa kakawanda uye kuzvimba kwematadza kunogona kuitika. |
| Utachiona hunoramba huchidzokororwa | Zvirwere zvekufema (dzihwa, kukosora), zvirwere zvemudumbu (kurwadziwa kwemudumbu), uye zvirwere zveganda (cellulitis) zvinogona kuitika kakawanda. |
Hunhu hwezviratidzo izvi hunogona kuchinja muhupenyu hwese. Kune vanhu vazhinji, kuoma kwezviratidzo kunoderera pavanosvika pakukura . Maronda emuromo nematambudziko emazino anowanzoonekwa muvechidiki, nepo musoro nehutachiona hwesinus (sinusitis) zvichiwanzoonekwa muvanhu vakuru.
Sei izvi zviri kuitika?
Kusashanda zvakanaka kwemasero eropa kunokonzerwa nekuchinja kwemajini . Chikonzero chikuru ndechekuchinja kwemajini eELANE mumuviri wedu.
Funga nezvejini seseti yemirairo inotaurira masero mumuviri wedu mashandiro awo. Jini reELANE rine mirairo yekugadzira enzyme inobatsira ma neutrophils kushanda zvakanaka. Kana paine chikanganiso kana shanduko mujini iri, ma neutrophils haagone kushanda zvakanaka.
Dambudziko iri rinogona kutorwa kubva kuvabereki kuenda kuvana, kana kuti rinogona kuitika panguva yekukura kwemwana asati aberekwa.
Nekuda kwekusakwana kwemajini uku,
- Muviri ungasakwanisa kugadzira ma neutrophils akakwana.
- Zvikasadaro, ma neutrophils anogona kufa nekukurumidza.
- Kana kuti ma neutrophils anogona kusashanda zvakanaka.
Chiremba, unoongorora sei izvi?
Zviratidzo izvi zvinowanzoonekwa kubva pakuzvarwa, saka chirwere ichi chinowanzoonekwa vachiri vacheche. Chiremba achafunga nezvezvinhu zvakati wandei kuti asimbise chirwere ichi.
- Nhoroondo yemhuri yechirwere ichi: Sezvo ichi chiri chirwere chinogara nhaka, chinoongororwa kuti chionekwe kana paine mumwe munhu mumhuri (vabereki, vanun'una kana hanzvadzi) ane chirwere ichi.
- Kuongororwa kweropa: Uku ndiko kwakakosha zvikuru. Chiremba wako achaongorora huwandu hwema neutrophil muropa rako kaviri kana katatu pasvondo kwemavhiki matanhatu . Izvi zvichaitwa kuti vaone kana huwandu hwema neutrophil ako huri kudzikira nguva nenguva.
- Maitiro ezviratidzo: Chiremba achanyatsoongorora kuwanda kwezviratidzo (anenge mavhiki matatu ega ega). Maitiro aya anobatsira kusiyanisa izvi nemamwe marudzi e neutropenia.
- Kuongororwa kwemajini: Dzimwe nguva kuongororwa kwemajini kunogona kukurudzirwa kusimbisa kana paine shanduko mujini reELANE.
Pakuongorora chirwere ichi, chiremba anofanira kubvisa mamwe marudzi e neutropenia ane zviratidzo zvakafanana, zvakaita se `Severe congenital neutropenia` (yaimbozivikanwa se `Kostmann syndrome`), `Autoimmune neutropenia`, uye `Idiopathic neutropenia`.
Ndezvipi zvinorapwa izvi?
Pane zvinangwa zvikuru zviviri zvekurapa: Chimwe ndechekurapa hutachiona huripo. Chimwe ndechekuwedzera huwandu hwema neutrophil uye kudzivirira hutachiona mune ramangwana.
| Nzira yekurapa | Mashandiro |
|---|---|
| Mishonga inorwisa mabhakitiriya | Izvi zvinopihwa kurwisa hutachiona hwemabhakitiriya hunoitika panguva iyo ma neutrophils ari mashoma. |
| Kurapa kweG-CSF | Uyu ndiwo mushonga mukuru uye unoshanda zvikuru. G-CSF (Granulocyte colony-stimulating factor) mushonga unokurudzira mupfupa wedu kuti ugadzire ma neutrophils akawanda (semuenzaniso filgrastim (Neupogen®)). Unopihwa sejekiseni uye mushonga wakachengeteka unogona kushandiswa kwenguva refu. |
| Kuisirwa kwemasero emudzi | Iyi inzira inoshandiswa chete kune avo vane chirwere chakanyanya uye vasingapindure kurapwa kweG-CSF. Munzira iyi, masero emuviri ane hutano anosimwa kuti atsive masero ane chirwere. |
Pane migumisiro yakaipa here yekurapwa kwacho?
Kurapwa kweG-CSF kunogona kukonzera migumisiro midiki. Zvisinei, vanachiremba vanowanzotanga kurapa chirwere ichi nedosi shoma, saka migumisiro yacho mishoma.
- Musoro
- Kurwadziwa mumapfupa nemajoini
- Kusvotwa uye manyoka
Zvinhu zvakaita seizvi zvinogona kuitika. Taura nachiremba wako nokungwarira nezvekurapa kwauri kuwana uye migumisiro yako.
Ndinofanira kufonera chiremba nguvai?
Kana iwe kana mwana wako muine cyclic neutropenia, zvakakosha kuti muwane rubatsiro rwechiremba kana mangoona zviratidzo zvehutachiona .
Nyatsoteerera zvinhu zvinotevera:
* Kupindwa nechando
* Kurwadziwa pane imwe nzvimbo mumuviri
* Kuzvimba kana kutsvuka kweganda
Kana ukaona chimwe chezviratidzo izvi, enda kuna chiremba wako nekukasika. Usazeza kuenda kuEmergency Department (ETU) kana zvichidikanwa.
Chii chatinofanira kuita kuti tizvidzivirire kubva kuzvirwere?
Pamusoro pekuzvidzivirira kubva kuzvirwere, unofanirawo kungwarira kana huwandu hwema neutrophil ako hwakaderera.
- Gara uchigeza maoko ako zvakanaka, kunyanya usati wadya uye mushure mekushandisa chimbuzi.
- Ramba uine hutano hwakanaka hwemuromo. Shamba mazino ako zuva nezuva uye enda kuna chiremba wemazino nguva nenguva .
- Wana majekiseni ese anokurudzirwa nenguva.
- Dzivisa kubata kumeso, maziso, uye mhino yako usina kugeza maoko ako.
- Inwa mishonga yako sezvakarairwa nachiremba wako uye ongororwa ropa rako nenguva.
Kunyangwe chirwere ichi chichitora hupenyu hwese, kurapwa kwakabudirira senge G-CSF kwave kubvumira vanhu vazhinji vane cyclic neutropenia kurarama hupenyu hwakajairika . Zvakakosha, nepo mamwe marudzi e neutropenia aine njodzi yekubatwa nekenza, senge leukemia, cyclic neutropenia haina.
Mharidzo Yekuenda Nayo Kumba
- Cyclic neutropenia chirwere chisingawanzoitiki chemajini umo huwandu hwemasero e-neutrophil anorwisa hutachiona hunoderera nguva nenguva.
- Zviratidzo (fivha, maronda emuromo) zvinowanzoonekwa kamwe chete pamavhiki matatu ega ega.
- Kuti zviongororwe, kuongororwa kweropa kunofanirwa kuitwa nguva dzose kwemavhiki akati wandei kuti zvionekwe kuti huwandu hwema neutrophil hwakafanana here.
- Nekuti kune mishonga inoshanda zvikuru senge G-CSF, varwere vanogona kurarama hupenyu hwakajairika.
- Zvakakosha kutsvaga rubatsiro rwechiremba kana wangoona zviratidzo zvehutachiona (fivha, kurwadziwa, kuzvimba).
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