Ganda rako nemachena emaziso ako zviri kuchinja here kuva yero? Ngatidzidzei zvakawanda nezveDubin-Johnson Syndrome!

Wakamboona here kuti ruvara rweganda rako kana machena emaziso ako anoita seari yero zvishoma? Kana kuti wakamboona here kuti weti yako iri yero yakasviba kupfuura zvayagara ichiita? Kana uri kusangana nezvinhu izvi, chimwe chikonzero chingangove chirwere chisingawanzoitiki asi chisina kunyanya kuipa chinonzi Dubin-Johnson syndrome . Saka, ngatitaurei nezvazvo zvakadzama, zviri nyore.

Chii chinonzi Dubin-Johnson Syndrome?

Zvichitaurwa zviri nyore, Dubin-Johnson syndrome chirwere chemajini chinokanganisa chiropa chedu. Chinoitika apa ndechekuti chinhu cheyero chinonzi bilirubin, chinogadzirwa mumuviri wedu, chinoungana panzvimbo pekuburitswa mumuviri nemazvo. Iye zvino ungave uchishamisika kuti bilirubin chii. Mushure menguva yakati, kana nguva yavo yekurarama yapera, masero matsvuku eropa mumuviri wedu anoputsika. Ndipo panogadzirwa bilirubin iyi. Kazhinji, bilirubin iyi inofanira kuburitswa muchiropa chedu pamwe chete nebile uye yoburitswa mumuviri semarara. Zvisinei, maitiro aya haaitike zvakanaka mumuviri wemunhu ane Dubin-Johnson syndrome. Saka, bilirubin inoungana muchiropa neropa, zvichikonzera zviratidzo zvakaita sejaundice . Ndipo apo ganda nemachena emaziso zvinoshanduka kuita yero.

Ndiani anonyanya kukanganiswa nemamiriro ezvinhu aya?

Dubin-Johnson syndrome chirwere chemajini , saka chinogona kukanganisa chero munhu, chero zera. Kuti ugare nhaka chirwere ichi, vabereki vako vese vanofanira kukupa jini. Izvi zvinonzi autosomal recessive inheritance. Semuenzaniso, kana ukagara nhaka jini kubva kune mumwe wevabereki vako chete, hauzoratidzi zviratidzo, asi uchava mutakuri wejini racho. Izvi zvinoreva kuti unogona kupa jini kuvana vako.

Mamiriro ezvinhu aya akajairika zvakadii?

Hapana nhamba dzakanyatsojeka dzekuti izvi zvakajairika sei, asi zvakajairika kuvanhu vanogara munyika dzakadai seIran, Iraq, Morocco, neJapan. Zvinofungidzirwa kuti munhu mumwe chete pavanhu chiuru nemazana matatu munyika idzodzo anogona kunge aine chirwere ichi.

Dubin-Johnson syndrome inokanganisa sei muviri wangu?

Dubin-Johnson syndrome inokonzerwa nekuunganidzwa kwe bilirubin yeyero muchiropa chako. Izvi ndizvo zvinoita kuti ganda rako nemaziso machena zvitaridzike seyero. Dzimwe nguva, paunenge uri mumba uye uri muchiedza chisina kujeka, ungasaona kutsvuka uku. Zvisinei, munzvimbo ine chiedza chakawanda, senge muzuva, kutsvuka uku kunonyanya kuoneka. Kazhinji, chinhu chekutanga chaunoona nezvekutsvuka uku kumeso.Zvadaro zvinogona kupararira kune dzimwe nhengo dzemuviri, dzakadai sechipfuva nedumbu. Paunotarisa mugirazi, kana ukavhura muromo wako wotarisa pasi perurimi rwako, unoona kuti washandukawo kuva yeyero ipapo.

Ndezvipi zviratidzo zveizvi?

Vanhu vazhinji vanoonekwa vaine Dubin-Johnson syndrome vane zviratidzo zvikuru zvejaundice, iyo inokonzerwa nekuunganidzwa kwebilirubin muchiropa. Izvi zvinoreva:

• Kutsvuka kweganda rako uye kuchena kwemaziso ako.
• Kuchinja kweruvara rweweti yako (kuchichinja kuita yero yakasviba kana kuti brown).

Dzimwe nguva, kana muviri uri pasi pekunetseka, semuenzaniso, kana uine chimwe chirwere, panguva yekuzvitakura, kana kana uri kushandisa mapiritsi ekudzivirira pamuviri (mishonga yekudzivirira pamuviri inonwiwa), ruvara rweyero urwu runogona kuwedzera.

Kuwedzera kune izvi, zvimwe zviratidzo zvidiki zvinogona kuitika, asi kazhinji hazvina kunyanya kuipa:

• Kunzwa kuneta zvinoreva kuti `(Kuneta)`.
• Kurwadziwa kudiki mudumbu repazasi (Abdominal Pain).

Chinhu chakakosha ndechekuti Dubin-Johnson syndrome chirwere chisina njodzi. Izvi zvinoreva kuti hachizokuvadzi hupenyu hwako zvakanyanya.

Kana ukaita mimwe miedzo, unogona kuona zvinhu zvakaita seizvi:

• Chiropa chako chine zvinhu zvakawanda, zvichiita kuti chiite sechitema (izvi zvinoongororwa nekutora chidimbu chidiki chenyama kubva pachiropa - chinonzi `Liver Biopsy` ).
• Chiropa chinogona kukura zvishoma ( Hepatomegaly ).

Chii chinokonzera Dubin-Johnson syndrome?

Chikonzero chikuru cheDubin-Johnson syndrome ikushanduka kwejini re'ABCC2'. Iri jini re'ABCC2' ndiro rinoita kuti pave nepuroteni inobatsira masero edu kubvisa tsvina. Kunyanya, puroteni iyi inobatsira masero echiropa kubvisa bilirubin (chinhu cheyero chinosara kubva pakuputsika kwemasero matsvuku eropa) uye kuiburitsa senyongo (mvura inobatsira kugaya chikafu).

Saka, kana uine Dubin-Johnson syndrome, muviri wako haugone kubvisa tsvina iyi inonzi bilirubin kubva mumasero ako. Nekuda kweizvozvo, zvinhu zvakaita sebilirubin zvinoungana mumuviri wako (izvi zvinonzi hyperbilirubinemia ). Ndosaka zviratidzo zvakaita sejaundice zvichionekwa.

Dubin-Johnson syndrome inoonekwa sei?

Chiremba wako achatanga akuongorora, obvunza nezvezviratidzo zvako, uye oona kana paine munhu mumhuri mako akambova nematambudziko akafanana (nhoroondo yezveutano hwemhuri).

Zvadaro, vacharaira mimwe miedzo yakati wandei kuti vasimbise chirwere ichi. Izvi zvinogona kusanganisira:

• Kuongororwa kwemifananidzo (semuenzaniso , X-ray , ultrasound scan ) kuti utarise chiropa chako.
• Kuongororwa kweropa (kunyanya bvunzo ye bilirubin )Poshi).
• Kuongororwa kweweti .
• Pamwe bvunzo apo chidimbu chidiki chechiropa chinotorwa ( 'Liver Biopsy ').

Kana bvunzo yebilirubin ikaratidza kuti bilirubin yako yakakwira zvakanyanya, zvinoreva kuti une chirwere chinonzi hyperbilirubinemia (bilirubin yakakwira muropa). Kana zviratidzo zvako zvikaramba zviripo, chiremba wako anogona kuraira kuongororwa ropa nemajini kuti awane jini riri kukonzera zviratidzo zvako. Iyi ndiyo chete nzira yekusimbisa kuti une Dubin-Johnson syndrome.

Ndezvipi zvinorapwa izvi?

Mashoko akanaka ndeekuti vanhu vazhinji vanoonekwa vaine Dubin-Johnson syndrome havadi kurapwa. Izvi zvinodaro nekuti haisi chirwere chakakomba. Zvisinei, kana kurapwa kuchidikanwa, kazhinji kunenge kuri kwechimwe chirwere kana maitiro ari kukonzera kuti mazinga e bilirubin akwire. Semuenzaniso, kana uine dzihwa, chiremba wako anogona kukuudza kuti unwe mvura yakawanda wozorora. Kana, kana mushonga wauri kutora uri kuita kuti zviratidzo zvako zviwedzere kuipa, chiremba wako anogona kukukurudzira kuti urege kutora mushonga iwoyo.

Chii chingaita kuti zviratidzo zveDubin-Johnson syndrome zviwedzere kuipa?

Zviratidzo zvejaundice zvinokonzerwa neDubin-Johnson syndrome zvinogona kugara kweupenyu hwese. Zvisinei, zviratidzo izvi zvinogona kuwedzera kana:

• Kana ukanwa doro.
• Kana uri kutora mapiritsi ekudzivirira pamuviri.
• Kana paine hutachiona.
• Kana uine pamuviri.

Kana uchinzwa sekuti zviratidzo zvako zviri kuwedzera kuipa, taura nachiremba wako nezvenzira dzekurapa dzinogona kukubatsira kuwana zororo.

Dubin-Johnson syndrome inogona kudzivirirwa here?

Nekuti chirwere ichi chinokonzerwa nemajini, hatigone kudzivirira Dubin-Johnson syndrome kuti isatange. Zvisinei, kana uchironga kuva nemwana uye uchida kuziva njodzi yekuti mwana wako ave nechirwere ichi, unogona kutaura nachiremba wako nezvekuongororwa kwemajini kana mazano ezvemajini .

Kana ndine Dubin-Johnson syndrome, chii chandinofanira kutarisira?

Maonero evanhu vane chirwere cheDubin-Johnson akanaka kwazvo. Hapana mushonga, uye kurapwa hakudiwi, uye zviratidzo zvinorapwa. Chinonyanya kukosha ndechekuti chirwere ichi hachikanganisi hupenyu hwemunhu.

Ndinofanira kuona chiremba wangu nguvai?

Kana zviratidzo zveDubin-Johnson syndrome zvikawedzera, kunyanya kana jaundice yako ichikonzera zviratidzo zvakafanana nefuruu, ona chiremba wako. Semuenzaniso:

• Kurwadziwa kwemudumbu .
• Kupindwa nechando .
• Kuneta .
• Kusvotwa kana kurutsa .

Mibvunzo ipi yandinofanira kubvunza chiremba wangu?

Unogona kubvunza chiremba wako mibvunzo yakaita seiyi:

• Zviratidzo zvangu zvinoda kurapwa here?
• Mwana wangu achagara nhaka chirwere ichi here?
• Ndinofanira kuitei kana ndichinzwa kusanzwa zvakanaka nekuda kwezviratidzo zvangu?

Chii chakasiyana pakati peDubin-Johnson syndrome neRotor syndrome?

Dubin-Johnson syndrome neRotor syndrome zvese zvirwere zvemajini. Zvese zvine zviratidzo zvakafanana, zvakaita sejaundice. Zvisinei, musiyano mukuru pakati pezvirwere zviviri izvi imhaka yazvo.

Dubin-Johnson syndrome inokonzerwa nekuchinja kwemajini e'ABCC2'. Zvisinei, Rotor syndrome inokonzerwa nekuchinja kwemajini e'SLCO1B1' uye 'SLCO1B3' .

Chimwe chinhu chakakosha chekucherechedza ndechekuti Rotor Syndrome inogona kukanganisa zvakanyanya mashandiro anoita muviri wemunhu mimwe mishonga. Saka, kana iwe kana mwana wako aine Rotor Syndrome, zvakakosha kuzivisa chiremba wako usati wanyora mimwe mishonga.

Uyezve, Rotor Syndrome haikonzeri kuchinja kweruvara rwechiropa. Zvisinei, chiropa chevanhu vane Dubin-Johnson Syndrome chinoita sechitema .

Zvakajairika kuti unzwe kunetseka kana ganda rako kana remwana wako rava yero. Kunyange hazvo jaundice ichiwanzoitika kuvana vachangoberekwa, jaundice inokonzerwa neDubin-Johnson syndrome chirwere chinoramba chiripo kweupenyu hwese.

Pakupedzisira, zvinhu zvekurangarira (Mharidzo Yekuenda Kumba)

Saka, ikozvino wava kuziva zvakawanda nezve Dubin-Johnson syndrome. Usazvidya moyo, haisi chirwere chakakomba. Chiremba wako achakutsanangurira kuti ndeapi marapirwo anodiwa kuderedza kutsvuka kwemaziso ako neganda, kana kana ukava nezvimwe zviratidzo. Chinhu chakakosha kutaura nachiremba wako nezvezviratidzo zvako nguva nenguva uye kuve nechokwadi chekuti une hutano hwakanaka. Unogona kurarama hupenyu hwakanaka uye hunofadza nechirwere ichi.

Dubin -Johnson syndrome, yellow fever, chiropa, bilirubin, zvirwere zvemajini, yellow yeganda, jaundice