Pamwe wakambonzwa izwi rekuti "mahormone" kakawanda, handiti? Mahormone aya anodzora zvinhu zvakawanda mumiviri yedu, zvakaita semanzwiro, kukura, kurara, uye nzara. Saka, nhasi tichataura nezvehomoni yakakosha zvikuru pakukura pabonde uye kugona kubereka, ndiko kuti, kubereka. Homoni iyoyo iFSH, kana kuti Follicle-Stimulating Hormone. Kunyangwe zita racho ringaita serakaoma, basa raro riri nyore kunzwisisa.
Zvichitaurwa zviri nyore, chii chinonzi FSH?
FSH ihomoni inogadzirwa negland repituitary, girandi diki riri muuropi hwedu. Basa rayo guru nderekudzora mashandiro emazai muvakadzi nematesticles muvarume.
Paunonzwa zita iri, vamwe vangafunga kuti izvi zvine chekuita nebvudzi. Asi hazvisizvo. Rimwe boka remahormone anonzi androgens rinokanganisa kukura kwebvudzi. FSH yakawana zita rayo nekuti inosimudzira masaga madiki ane mvura anonzi ovarian follicles mumaovari evakadzi. Aya mafollicle ane mazai.
Ndeapi mabasa ehomoni yeFSH?
Homoni yeFSH inokosha nenzira dzakasiyana pamatanho akasiyana ehupenyu hwedu. Ngationei kuti sei.
Kukura kwemwana ari mudumbu
Zvinoshamisa kuti, panguva yemwedzi mitatu yechipiri neyechitatu yekuzvitakura, kubva pamavhiki angangoita gumi nematatu kusvika pakusununguka, pituitary gland yemwana inotangawo kugadzira mahormone anonzi FSH neLH (Luteinizing Hormone). Mahormone aya anosvika pakati pekuzvitakura, sezvo follicle yekutanga yemwana kana seminiferous tubule inokura.
Munguva yekuyaruka
Munguva yehudiki, huwandu hweFSH hunowanzova hwakaderera zvikuru. Zvisinei, sezvo kuyaruka kuri kusvika, kazhinji pakati pemakore gumi nemana, hypothalamus iri muuropi inoburitsa hormone inonzi GnRH (Gonadotropin-releasing hormone). GnRH iyi inozivisa pituitary gland kuti itange kugadzira FSH neLH. Apa ndipo panotanga kukura pabonde uye shanduko dzemuviri dzine chekuita nazvo.
- Vakomana: FSH neLH zvinoshanda pamwe chete kukurudzira machende kuti agadzire testosterone . Hormone iyi ndiyo inokonzera shanduko muvakomana panguva yekuyaruka, zvakaita sekukura kwebvudzi mumuviri, kudzika kwezwi, uye kugadzirwa kwembeu.
- Muvasikana: FSH neLH zvinoshanda pamwe chete kukurudzira maovari kuti agadzire hormone inonzi estrogen . Iyi hormone ndiyo inokonzera kukura kwemazamu uye kutanga kwekuenda kumwedzi .
Vakadzi vari kumwedzi
Basa guru rehomoni yeFSH nderekudzora kutenderera kwemwedzi kwemukadzi ari kumwedzi. Zvichitaurwa zviri nyore, FSH inokurudzira kukura kwemasero emudumbu mumazai, ichigadzirira mazai kuti atange kubuda kwechibereko. Sezvo masero aya achikura, anoburitsa estrogen neprogesterone shoma muropa.
Pakati pemazuva 6 ne14 ekuenda kumwedzi, FSH inokonzera kuti mafollicles akawanda mu ovary atange kukura. Asi panosvika mazuva 10-14, follicle imwe chete ndiyo inenge yakura kuita zai rakakwana. Panosvika zuva re14, panenge paine kuwedzera kwakamwe kamwe kwehomoni yeLH. Izvi zvinoita kuti follicle yakakwana ibude yoburitsa zai. Izvi ndizvo zvatinodaidza kuti ovulation .
Mushure mekubuda kwembeu, follicle yakaputika inova gland renguva pfupi rinonzi corpus luteum, rinoburitsa huwandu hwakawanda hwehormone progesterone. Iyi progesterone inomisa kugadzirwa kweFSH uye inogadzirira madziro echibereko kuti akwanise kubata pamuviri.
Zai rinofamba richidzika muchubhu yefallopian kwemazuva angangoita mashanu risati rasvika muchibereko. Kana rikasanganiswa zvakanaka nembeu panguva iyi, pamuviri unoitika. Kana kuberekwa kukasabatanidzwa, corpus luteum inoputsika pakupera kwekuenda kumwedzi uye mazinga eprogesterone anoderera. Mazinga eFSH anobva atanga kukwira zvakare, uye kumwedzi kunotevera kunotanga.
Zvevarume
Basa guru rehomoni yemurume inonzi FSH nderekukurudzira kugadzirwa kwembeu . FSH inobatsirawo kuchengetedza kugadzirwa kwembeu nekushanda ne testosterone, iyo inogadzirwa neLH.
Kugadzirwa kweFSH kunodzorwa sei?
Iyi inzira yekudzora yakaoma kunzwisisa. Yakafanana nekushanda kwekambani hombe. Tinoidaidza kuti hypothalamic-pituitary-gonadal axis. Zvikamu zveuropi (hypothalamus, pituitary gland) uye gonads (mazai/machende) muhurongwa uhwu zvinogara zvichitaurirana.
1. Kutanga: Chekutanga, hypothalamus inoburitsa hormone inonzi GnRH.
2. Kukurudzira: GnRH iyi inoenda kugland repituitary yoiudza kuti igadzire mahormone eFSH neLH.
3. Chiito: FSH neLH, zvinogadzirwa negland repituitary, zvinofamba nemuropa zvobatana nemaovari kana machende (gonads) kuti zvidzore mashandiro azvo.
4. Mhinduro: Zvadaro, mahormone anogadzirwa nemazai nematesticles (akadai seestrogen netestosterone) anotumira zviratidzo kuuropi kuti zviudze kuti GnRH, FSH, neLH yakawanda sei. Izvi zvinoenderera mberi mudenderedzwa.
Kana paine kakusashanda zvakanaka mune iyi system, huwandu hwemahormone mumuviri hunogona kukanganiswa.
Mazinga eFSH akajairika akaita sei?
Mwero weFSH wakajairika unosiyana zvichienderana nezera, murume kana mukadzi, uye zuva rekuenda kumwedzi kuvakadzi. Zvakakosha kuti mwero wenguva dzose unogona kusiyana zvishoma pakati pemarabhoritari. Saka, zvakakosha kuenzanisa zvawakawana nemwero wenguva dzose wemarabhoritari uri pamushumo wako. Kana uine mibvunzo nezve zvawakawana, iva nechokwadi chekutaura nachiremba wako.
Pazasi pane zviyero zvinogamuchirwa. Chiyero chechiyero i mIU/mL (milli-international units pa milliliter).
| Danho | Nhamba yeFSH yakajairika yevarume (mIU/mL) |
|---|---|
| Usati wasvika pakuyaruka | 0 kusvika 5.0 |
| Munguva yekuyaruka | 0.3 kusvika 10.0 |
| Mukukura | 1.5 kusvika 12.4 |
| Danho | Nhamba yeFSH yakajairika yevakadzi (mIU/mL) |
|---|---|
| Usati wasvika pakuyaruka | 0 kusvika 4.0 |
| Munguva yekuyaruka | 0.3 kusvika 10.0 |
| Munguva yekukura (menopause) | 4.7 kusvika 21.5 (izvi zvinosiyana zvichienderana nedanho rekufamba) |
| Mushure mekuenda kumwedzi | Kubva pa25.8 kusvika pa134.8 |
Pane mwero weFSH wakakodzera here pakubata pamuviri?
Uyu mubvunzo unokosha zvikuru kune vakaroorana vanotarisira kuva nevana. Kuyera huwandu hweFSH kwakakosha pakuongorora kuti munhu anogona kubereka here. Nguva yakanakisisa yekuita bvunzo iyi izuva rechitatu rekuenda kumwedzi (zuva rekutanga rekuenda kumwedzi rinoonekwa sezuva rekutanga).
Ongororo yemigumisiro yekurapwa kweIVF (In Vitro Fertilization) yakaratidza kuti avo vane mazinga eFSH ari pasi pe15 mIU/mL pazuva rechitatu vaive nemukana wakakura wekubata pamuviri kupfuura avo vane mazinga eFSH ari pakati pe15 ne24.9. Avo vane mazinga eFSH ari pamusoro pe25 vaive nemukana wakaderera wekubata pamuviri.
Asi izvi hazvirevi kuti unogona kuita sarudzo zvichibva pamazinga eFSH chete. Kune zvimwe zvinhu zvakawanda zvinokanganisa kubereka. Saka zvakanaka kutaura nachiremba wako nezvemazinga ako eFSH, pamwe chete nezvinetso zvekubereka.
Chii chinorehwa neFSH level yakakwira?
Kazhinji, kana huwandu hweFSH hwakakwira kupfuura zvakajairwa, zvinoreva kuti pane dambudziko nemazai kana machende .
Fungidzira kuti maovari kana machende haasi kugadzira estrogen kana testosterone yakakwana. Zvadaro, pituitary gland iri muuropi inozviziva uye inofunga kuti, "Zvakanaka, ndinoda kutumira FSH yakawanda kuti zvinhu izvi zvishande," uye inoburitsa FSH yakawanda muropa. Asi nekuda kwedambudziko nemagonads, haakwanise kupindura zvakanaka huwandu hweFSH huri kuuya. Tinodana chirwere ichi kuti primary hypogonadism . Zvinotevera zvinogona kukonzera izvi:
- Zvirema zvekuzvarwa nazvo:
- Klinefelter syndrome muvanhurume
- Turner syndrome muvakadzi
- Zvikonzero zvinotevera:
- Kurapwa nemwaranzi kana chemotherapy yekenza
- Kukuvara kwemazai kana machende
- Kuderera kwemazinga emahormone nekukwegura
- Zvimwe zvirwere zve autoimmune
- Utachiona hwakadai semapundu
Uyewo, kuenda kumwedziMazinga eFSH evakadzi anokwira zvechisikigo pavanenge vachiburitsa zai. Izvi zvakajairika. Kana mazinga eFSH evana akakwira kupfuura zera ravo uye hunhu hwepabonde huri kukura, zvinogona kuva chiratidzo chekuyaruka kwevana vasati vasvika zera .
Chii chinorehwa neFSH level yakaderera?
Kana huwandu hweFSH hwakaderera pane hwakajairwa, zvinowanzo ratidza dambudziko negland repituitary kana hypothalamus . Nekuti uropi hausi kuratidza kugadzirwa kweFSH, maovari kana machende haashande zvakanaka. Dambudziko iri rinonzi hypogonadotropic-hypogonadism .
Izvi zvinogona kunge zvichikonzerwa ne:
- Matambudziko egland repituitary: Zvinhu zvakaita se pituitary adenomas zvinogona kukonzera kuti gland riome kana kukuvara, izvo zvinogona kukanganisa kugadzirwa kwemahormone.
- Matambudziko eHypothalamic: Zvirwere zvisingawanzoitiki zvemajini zvakaita seKallmann syndrome zvinogona kukonzera kudzikira kwekugadzirwa kwehomoni yeGnRH, izvo zvinogona kukonzera kudzikira kwemazinga eFSH.
Ndezvipi zviratidzo zvemazinga asina kujairika eFSH?
Kunyangwe huwandu hweFSH hwakaderera kana kuti hwakakwira, zviratidzo zvinowanzofanana nedze hypogonadism , kureva kuti, gonads dzisingashande zvakanaka. Zviratidzo izvi zvinosiyana zvichienderana nezera uye murume kana mukadzi.
| Mukana / Munhu | Zviratidzo zvinoonekwa |
|---|---|
| Vacheche vachangoberekwa | - Nhengo diki isina kujairika (Micropenis) - Machende asina kudzika |
| Vana vasvika pakuyaruka | - Kusakura kwemazamu muvasikana - Kusavapo kana kunonoka kuenda kumwedzi (Amenorrhea) - Machende evakomana haana kukura. - Kuderera kwehuwandu hwekukwira |
| Murume mukuru | - Kudzikira kwechido chepabonde - Kuneta zvakanyanya - Kusabereka, Azoospermia - Kusashanda zvakanaka kwenhengo dzesikarudzi (Erectile Disorder) - Kuwedzera mazamu (Gynecomastia) -Kuderedza bvudzi remuviri nerechiso |
| Vakadzi vakuru | - Kudzikira kwechido chepabonde - Kuneta zvakanyanya - Kusabereka, matambudziko ekubuda kwechibereko - Kupisa kunopisa - Kuenda kumwedzi kusingawanzoitiki kana kuti kurega kuenda kumwedzi - Kudzikira kwebvudzi munzvimbo yakavanzika |
Mazinga eFSH anoyerwa sei?
Huwandu hweFSH yako hunogona kuyerwa nekuongororwa ropa kuri nyore . Pamwe chete nebvunzo iyi, chiremba wako anogona kukurudzira kumwe kuongororwa kwemahormone kuti awane mufananidzo wakazara wemamiriro ako ezvinhu.
- Hormone yeLuteinizing (LH)
- Testosterone
- Estradiol uye/kana progesterone
Miedzo iyi inowanzoitwa:
- Kuti uwane chikonzero chekusabereka
- Kuongorora matambudziko ane chekuita nemazai kana machende
- Kuongorora matambudziko ane pituitary gland kana hypothalamus
- Kutsvaga zvikonzero zvekuenda kumwedzi zvisina kurongeka
- Kuziva kana kuenda kumwedzi kwava kusvika
- Kuti uwane zvikonzero zvekushomeka kwembeu dzemurume
- Kuti tiwane zvikonzero zvinoita kuti vana vasayaruka kana kuti vasayaruka nekukurumidza.
Ndinofanira kuona chiremba rini?
Kana iwe kana mwana wako muine chimwe chezvirwere zvinotevera kana kupfuura, zvakakosha kuti muone chiremba kuti akupei mazano.
- Kana uine zviratidzo zve hypogonadism zvataurwa pamusoro apa (zvakadai sekudzikira kwechido chepabonde, kuneta zvakanyanya, kushaya mbereko).
- Kana mwana wako ari kutanga kuyaruka nekukurumidza kana kuti kunonoka kupfuura zvakajairika .
- Kana uri kutarisira mwana asi uchinetseka nekubata pamuviri .
FSH ihormone inokosha pakukura kwepabonde uye kubereka mumuviri wedu. Nekuti yakabatana zvakanyanya nemamwe mahormone akawanda, dzimwe nguva huwandu hwayo hunogona kunge husina kujairika. Asi usazvidya moyo nazvo. Kana uchifunga kuti iwe kana mwana wako mune dambudziko neizvi, taura nachiremba. Vanogara vakagadzirira kukubatsira.
Mharidzo Yekuenda Nayo Kumba
- FSH ihomoni inogadzirwa negland repituitary riri muuropi uye inokosha pakuyaruka, kuenda kumwedzi, uye kugadzirwa kwembeu.
- Kuwanda kweFSH kunowanzo ratidza dambudziko nemazai kana machende, nepo kuderera kweFSH kuchigona kuratidza dambudziko muuropi (pituitary/hypothalamus).
- Mazinga eFSH anowedzera muvakadzi panguva yekuenda kumwedzi.
- Kuongororwa ropa kuri nyore ndiko chete kwaunofanira kuziva nezvehuwandu hweFSH yako, asi usaedze kutsanangura zvabuda wega.
- Gara uchikurukura nachiremba wako zvabuda mumushumo wako uye chero matanho aunofanira kutora zvichibva pairi.
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