Unodawo kuziva nezve Hairy Cell Leukemia here? Ngatikurukurei!

Unonzwa wakaneta nguva dzese here? Kana kuti unorwara nedzihwa nezvirwere zvinogara zvichiitika? Dzimwe nguva zvinhu izvi zvinoonekwa sezvinowanzoitika, asi hazviwanzo kuva chiratidzo chechimwe chinhu. Nhasi tichataura nezvegomarara reropa risingawanzoitiki asi rinokosha zvikuru rakakosha kuziva. Rinonzi "Hairy Cell Leukemia".

Chii chinonzi "Hairy Cell Leukemia" ichi?

Zvichitaurwa zviri nyore, iyi imhando yegomarara rinotanga muropa. Tine chikamu chemuviri wedu chinonzi bone marrow. Kubva mu bone marrow iyoyo ndipo panogadzirwa mhando dzemasero ari muropa redu. Paaya, B-cells (dzinonziwo `B lymphocytes`) imhando yemasero machena eropa. Basa rawo guru nderekurwisa utachiona hunopinda mumuviri wedu uye kutidzivirira kubva kuzvirwere.

Saka, muchirwere ichi chinonzi `Hairy Cell Leukemia`, chinoitika ndechekuti bone morrow yako inoburitsa masero eB asina kujairika . Paunotarisa masero aya asina kujairika uchishandisa maikorosikopu, unogona kuona kuti ane tumaburi tudiki twakaita sebvudzi tunobuda maari. Ndosaka chirwere ichi chichinzi `hairy cell leukemia'' nekuda kwechitarisiko ichocho chema "hairy". Chinoonekwa nevanoongorora masero aya vachishandisa maikorosikopu.

Sei izvi zvichiitika? Chii chinoitika kumuviri?

Kunyangwe zvisati zvazivikanwa kuti sei izvi zvichiitika, pane zvinhu zvishoma zvinoitika mumuviri kana chirwere ichi chikaitika. Fungidzira kuti une bindu remuriwo, uye chii chinoitika kana sora rikakura zvisina kudzoreka? Muriwo wakanaka unorasikirwa nenzvimbo uye haukure zvakanaka, handiti? Ndizvo zvinoitikawo pano.

• Migumisiro yemupfupa: Masero eB asina kujairika anotanga kuungana mupfupa, semasora. Izvi zvinoderedza kugona kwekugadzira masero machena eropa ane hutano, masero matsvuku eropa, uye maplatelet (masero anobatsira kuumba ropa).
• Kuzvimba kwema lymph nodes ne spleen: Masero aya asina kujairika muma lymph nodes edu ne spleen anotanga kupatsanurana nekuwanda, zvichiita kuti nhengo idzodzo dzizvimbe.
• Migumisiro yechiropa: Dzimwe nguva masero aya asina kujairika anogona kupararira kuchiropa kuburikidza neropa uye kuchikuvadza. Izvi zvinogona kukonzera kuungana kwemvura mudumbu (chirwere chinonzi `ascites`).

Izvi zvakajairika here?

`Hairy Cell Leukemia` chirwere chisingawanzoitiki . Kunyangwe munyika yakaita seAmerica, chinowanikwa muvanhu vanosvika zana pavanhu zviuru. Zvinonziwo chirwere ichi chinowanikwa zvakanyanya pakati pevanhu vachena kupfuura mamwe marudzi.

Zviratidzo zvacho ndezvipi?

Dzimwe nguva vanhu vane Hairy Cell Leukemia vanogona kusava nezviratidzo . Zvisinei, kana zviratidzo zvikaonekwa, zvinogona kusanganisira:

• Kuneta: Kuneta uku kunogona kuitika nekuda kwekudzikira kwemasero matsvuku eropa (anemia).
• Fivha uye hutachiona hunowanzoitika:Nekuda kwehuwandu hushoma hwemasero machena eropa anobatsira kurwisa hutachiona, dzihwa rinowanzoitika uye hutachiona hwakanyanya hunowanzoitika.
• Kurwadziwa kwemudumbu rekuruboshwe: Kana masero asina kujairika mudumbu rekuruboshwe akaungana uye akaita kuti dumbu rizvimbe, unogona kunzwa kurwadziwa mudumbu rekuruboshwe. Bhudzi rinogona kukura uye kuita kuti unzwe wakaguta, uye unogona kunzwa wakaguta kunyangwe mushure mekudya zvishoma. Unogonawo kuderedza uremu usingaedze.
• Kurwadziwa mudumbu repazasi kurudyi: Kana chiropa chikakura, unogona kurwadziwa kurutivi rwerudyi.
• Kutadza kufema: Ichi chimwe chiratidzo chekushaya ropa.
• Ma lymph nodes akazvimba: Mapundu asingarwadzi anogona kuoneka mumutsipa, muhapwa, uye mudumbu.
• Kukuvara kana kubuda ropa kusingawanzoitiki: Nekuti mupfupa haubudisi maplatelet akakwana, anobatsira kuumba ropa, kunyangwe mavanga madiki uye kubuda ropa kunogona kuitika.

Zvakakosha: Kuva nechimwe chezviratidzo izvi kana kupfuura hazvirevi kuti une Hairy Cell Leukemia. Zvisinei, kana zviratidzo izvi zvikaramba zviripo, zvakanaka kutsvaga rubatsiro rwechiremba.

Ndezvipi zvinokonzera? Pane zvinhu zvinogona kukonzera njodzi here?

Nyanzvi hadzisati dzaziva chikonzero chaicho cheHairy Cell Leukemia. Zvisinei, tsvakiridzo yakawana kuti vanhu vanosvika 90% vane chirwere ichi vane majini akasiyana. Chinokanganisa jini rinonzi BRAF. Jini iri rinobatsira masero kukura. Saka, parinochinja, masero asina kujairika anotanga kukura uye kuwanda zvisingadzoreki. Kuchinja kwemajini uku kunoitika mushure mekuzvarwa kwedu. Zvisinei, hazvisati zvanyatsojeka kuti chii chinokonzera kuchinja ikoko.

Zvisinei, zvimwe zvinhu zvinokonzera njodzi zvakawanikwa zvinowedzera njodzi yekubatwa nechirwere ichi:

• Zera: Chirwere ichi chinowanzo bata vanhu vari pakati pemakore makumi mana nemakumi manomwe. Avhareji yezera rekuonekwa kwechirwere ichi imakore angangoita makumi mashanu nemasere.
• Murume kana Mukadzi: Chirwere ichi chinowanzoitika muvarume kupfuura vakadzi.
• Kuonekwa neAgent Orange: Vaongorori vanotenda kuti pane hukama pakati pemakemikari aya neB-cell leukemia isingaperi uye lymphoma (kusanganisira hairy cell leukemia).

Ndezvipi zvinetso zvinogona kukonzera izvi?

Kubuda kwemasero ebvudzi (hairy cell leukemia) kunokonzera kudzikira kukuru kwehuwandu hwemasero machena mumuviri wako anorwisa hutachiona, izvo zvinowedzera njodzi yako yekubatwa nehutachiona . Izvi zvinogona kunge hutachiona hwebhakitiriya, hwehutachiona, kana hwefungus. Dzimwe nguva, hutachiona uhwu hunogona kutyisidzira hupenyu.

Pane mukana mudiki wekuwana mhando yechipiri yekenza makore mazhinji mushure mekuongororwa nekurapwa. Semuenzaniso, zvidzidzo zvakatevera vanhu vakange varapwa zvakanaka neHairy Cell Leukemia kwemakore gumi kusvika makumi maviri zvakaratidza kuti vamwe vakange vawana dzimwe kenza.

Chirwere ichi chinoonekwa sei?

Kana ukaona chiremba, achakubvunza nezvezvinhu zvakaita sekuti zviratidzo zvako zvakatanga riini uye kana uchigara uchibatwa nezvirwere. Achakubvunzawo nezvenhoroondo yako yehutano. Zvadaro, vachakubvunza nezvemuviri wako. Vanogonawo kutarisa ma lymph nodes, spleen, nechiropa chako kuti hazvina kuzvimba here.

Zvadaro, unogona kutumirwa kuna chiremba weropa kana chiremba wekenza kuti uongororwe zvimwe kuti usimbise chirwere chacho. Miedzo iyi inogona kusanganisira:

• Kuverengwa kweropa kwakazara (CBC) uye kusiyana: Izvi zvinoyera huwandu hwemasero matsvuku nemachena eropa, pamwe nemaplatelet. Kusiyana uku kunoyera huwandu hwemarudzi akasiyana emasero machena eropa.
• Kuongororwa kweropa rekunze: Vanachiremba vanoongorora ropa vachishandisa maikorosikopu kuti vaone masero asina kujairika ane "bvudzi" rakafanana nebvudzi.
• Kutsvaga mapfupa emubofu uye kuongorora mapfupa emubofu: Miedzo iyi inogona kuona masero asina kujairika mubofu remubofu.
• CT scan (Computed tomography - `CT` scan): `CT` scan inogona kutora mifananidzo yakadzama yemukati memuviri. Izvi zvinogona kushandiswa kuona saizi yepleen, chiropa, uye lymph nodes, kana kuti ultrasound yedumbu.
• Kuyerera kwemasero emudumbu: Izvi zvinoongorora ropa nemwongo wemapfupa kuti uone masero asina kujairika, akadai semasero ebvudzi. Zvinoongororawo saizi, chimiro chemasero, uye kuvapo kwezviratidzo zvegomarara. Zviratidzo zvegomarara zvinogona kuva mapuroteni anogadzirwa nemasero egomarara.

Inorapwa sei?

Kana uine hutachiona, unofanira kutanga wahurapa. Zvadaro, mamwe marapirwo achatanga kudzora zviratidzo zve 'Hairy Cell Leukemia'. Zvisinei, sezvatakambotaura, havasi vese vanozova nezviratidzo. Kune vanhu vakadaro, chiremba wako weropa kana chiremba wekenza anogona kukupa nzira inonzi active surveillance . Kana paine zviratidzo, vanogona kukupa mishonga.

Kutarisa Kwakasimba

Hairy Cell Leukemia chirwere chinokura zvishoma nezvishoma . Zvinogona kutora makore kuti zviratidzo zvioneke. Nekuti kurapwa kwegomarara kunogona kukonzera migumisiro uye matambudziko, kana usina zviratidzo, chiremba wako anogona kusarudza kunonoka kutanga kurapwa kusvika zviratidzo zvaonekwa.

Munguva yekuongororwa kwakaitwa, muchaona chiremba wenyu mwedzi mitatu kusvika mitanhatu yega yega. Munguva yekushanya ikoko:

• Vachakubvunza nezveutano hwako, kunyanya kana uchinzwa kuneta kupfuura zvawagara uchiita.
• Kuongororwa kwemuviri kuchaitwa kuti chiropa nechiropa zvionekwe kana zvakazvimba.
• Kuongororwa kweropa kunorayirwa kuti kuonekwe huwandu hwemasero eropa nemaplatelet.

Zvinogona kuoma mupfungwa kumirira kuti zviratidzo zvitange kuonekwa usati watanga kurapwa. Asi chiremba wako achanzwisisa manzwiro ako uye achatsanangura kuti sei zvichikurudzirwa kuti utariswe.

Mishonga

Mushonga mukuru wekurapa vanhu vane vhudzi releukemia ichemotherapy . Mishonga inonyanya kushandiswa yekurwisa kenza ndeyeCladribine (Leustatin®) kana Pentostatin (Nipent®).

Kana chemotherapy ikasashanda, kana chirwere chikadzoka, kune mamwe marapirwo:

• Kurapa Nezvirwere Zvinodzivirira Muviri: `Rituxan®)` mushonga we`monoclonal antibody` unoshandiswa pakurapa `Hairy Cell Leukemia`. Unogona kupiwa semushonga wekutanga nechemotherapy kana chirwere chikadzoka. Imwe immunotherapy ndeye `Recombinant Interferon Alfa-2b (Intron A®)`.
• Kurapa kwakanangana: Kune Hairy Cell Leukemia inodzokororwa, mishonga inonzi Rituximab neMoxetumomab pasudotox (Lumoxiti®) (iyi imhando yeantibody-drug conjugate) inogona kushandiswa.
• Kuvhiyiwa kweSplenectomy: Kashoma, kuvhiyiwa uku kunogona kukurudzirwa kana mishonga yakadai sechemotherapy isingabatsire uye splen ikaramba ichizvimba nekuda kwemasero asina kujairika muslen.

Pane migumisiro yakaipa here yekurapwa kwacho?

Kufanana nechero nzira yekurapa kenza, inogona kuva nemigumisiro yakaipa. Kunyanya, mishonga yechemotherapy ye hairy cell leukemia inowedzera njodzi yezvirwere zvinouraya . Chiremba wako achakutsanangurira matanho aunogona kutora kudzivirira hutachiona uye shanduko dzipi mumuviri wako dzingangove zviratidzo zvehutachiona.

Chii chaungatarisira paunenge uchirarama nechirwere ichi?

Parizvino hapana mushonga weHairy Cell Leukemia. Zvisinei, tsvakurudzo inoratidza kuti kurapwa, kusanganisira chemotherapy, kunogona kuchengetedza chirwere ichi chichiri kupora kwemakore gumi kana kupfuura . Kurerukirwa kunoreva kuti hauna zviratidzo uye hapana zviratidzo zvechirwere zvinogona kuwanikwa pabvunzo. Chidzidzo chakaongorora zvakaitika kuvanhu vane Hairy Cell Leukemia chakaona kuti mushure mekurapwa, vanogona kurarama kwenguva yakareba sevanhu vasina chirwere ichi.

Zvisinei, hairy cell leukemia inogona kudzoka makore akati wandei mushure mekurapwa kwekutanga. Zvisinei, kana izvozvo zvikaitika, kune mishonga inogona kudzorera chirwere ichi kumashure.

Vanhu vazhinji vanoda rubatsiro rwehutano nerubatsiro rwehupenyu hwavo hwese, sezvo vanachiremba vachifanira kutarisa kana chirwere ichi chichidzoka zvakare. Kunyangwe uine chirwere asi usina zviratidzo, uchafanirwa kuongororwa uye kugadzwa nguva yekutevera mwedzi mitatu kusvika mitanhatu yega yega mushure mekuonekwa kuti une chirwere ichi.

Mwero wekupora uri papi?

Sekureva kweLeukemia and Lymphoma Society, 90% yevanhu vanorapwa nemushonga wechemotherapy weCladribine vanorarama makore mashanu mushure mekurapwa. Zvisinei, fungidziro yako - zvinoitika mushure mekurapwa - zvinoenderana nezvinhu zvakawanda . Zera rako, hutano hwako hwese, zviratidzo, uye kuti muviri wako unopindura sei kurapwa zvese zvine chekuita nazvo. Kana uine mibvunzo nezveizvi, bvunza chiremba wako.

Ndinofanira kuchengetedza sei hutano hwangu?

Leukemia yeHairy Cell inowedzera njodzi yezvirwere zvinouraya. Unogona kusimbisa masoja emuviri wako uye kuzvidzivirira kubva kuzvirwere . Heano mamwe mazano:

• Idya chikafu chine hutano: Zvinhu zvakaita semichero, miriwo, mapuroteni asina mafuta akawanda, uye zviyo zvakakwana zvinobatsira kuti dziviriro yemuviri ishande zvakanaka.
• Kurovedza muviri zuva nezuva: Kugara uchiita maekisesaizi zuva nezuva kwakanakira hutano hwako, kusanganisira masoja emuviri wako.
• Wana hope dzakakwana: Kusawana hope dzakakwana kunogona kuita kuti dziviriro yemuviri wako isashande zvakanaka.
• Wana majekiseni ako panguva: Majekiseni anodzidzisa muviri wako kurwisa utachiona hunokonzera zvirwere. Taura nachiremba wako nezvekuti ndeapi majekiseni aunoda uye kuti ungaawana riini.

Unofanira kuona chiremba rini?

Hairy Cell Leukemia pamwe nekurapwa kwayo zvinogona kuwedzera njodzi yako yekubatwa nezvirwere zvakakomba, dzimwe nguva zvinouraya. Enda kuna chiremba nekukasika kana uine zviratidzo izvi:

• Fivha inodarika madhigirii Celsius makumi matatu nemasere (100.4 degrees Fahrenheit) uye isingaderere.
• Huro inorwadza inogara kwemazuva mashoma kana kuti inowedzera kuipa.
• Marwadzo emudumbu asingapere kana kuti anowedzera.

Pfupiso uye Pakupedzisira (Mharidzo Yekuenda Kumba)

Pamwe wave kunzwa kuneta kupfuura zvawagara uchiita pasina chikonzero. Kana kuti pamwe wave uchifunga nezvechirwere chekufema chisina kupera pasinei nemishonga yawave uchitora. Iye zvino bvunzo dzaratidza kuti une kenza yeropa isingawanzoitiki inonzi `Hairy Cell Leukemia`, iyo isingarapiki zvachose kana ukairapa.

Asi musazvidya mwoyo . Kune mishonga inogona kuchengetedza chirwere ichi kwemakore pasina zviratidzo. Kurerutswa kwenguva refu kunoreva kuti timu yenyu yehutano ichaongorora hutano hwenyu kweupenyu hwese. Uye, kana Hairy Cell Leukemia ikadzoka, vaongorori vari kuramba vachitsvaga nzira dzekudzosera chirwere ichi ku 'rerutswa'.

Pane zvinhu zvaunogona kuita iwe pachako. Semuenzaniso, kurapwa kwegomarara kunogona kuwedzera njodzi yako yekutapukirwa. Bvunza chiremba wako nezvemajekiseni uye mamwe matanho aunogona kutora kuderedza njodzi yako yekutapukirwa.Hausi wega, kune vanachiremba nevashandi vehutano vanokubatsira parwendo urwu.

` Masero Ebvudzi Leukemia, leukemia, kenza yeropa, masero eB, mupfupa, chirwatata, zviratidzo