Kana mumwe munhu mumhuri yako, zvichida amai vako vaunoda, baba, kana ambuya, vachirwara nechirwere cheAlzheimer, tinoziva kuti zvinorwadza sei. Zvinosuwisa kuona ndangariro yemudiwa wako ichinyangarika zvishoma nezvishoma. Zvisinei, pakati pemamiriro ezvinhu akaoma aya, tiri kutaura nezvenhau inounza tariro. Iyi haisi mushonga wakakwana wechirwere, asi inogona kuva danho rinokosha mberi.
Mashoko matsva aya ndeapi?
Munguva pfupi yapfuura, boka revapi vemazano reUS Food and Drug Administration (FDA) vakabvumirana kuti mushonga mutsva weAlzheimer's ushandiswe. Zita remushonga uyu
ndiDonanemab . Unokurudzirwa kuvarwere
vari muchikamu chekutanga chechirwere ichi. Kubvumidzwa kweboka iri remazano kunoreva kuti pane mukana mukuru wekuti FDA ichapa mvumo yakazara kumushonga uyu munguva pfupi iri kutevera. Izvi zvinhu zvikuru, nekuti kuuya kwemushonga mutsva wechirwere chakakomba seAlzheimer's itarisiro huru.
Donanemab inoshanda sei?
Zvakanaka, ngationei kuti mushonga uyu unoshanda sei. Izvi zvakaoma zvishoma, asi ndichatsanangura zviri nyore. Donanemab rudzi rwemushonga unonzi
monoclonal antibody . Zvichitaurwa zviri nyore, ipuroteni yakakosha inogadzirwa murabhoritari kurwisa chinhu chaicho uchishandisa zvikamu zvemuviri wedu wekudzivirira muviri. Chii chinonangwa nemushonga uyu?
Iamyloid plaques , ayo anofungidzirwa kuti ndiwo anokonzera chirwere cheAlzheimer's. Kungofanana nengura inoungana mumapombi edu emvura, maplaques aya anoungana pakati pemasero etsinga muuropi uye anovhiringidza mashandiro awo. Chinoitwa naDonanemab ndechekuona maplaques aya uye kubatsira kubvisa.
Chinhu chakakosha ndechekuti iyi haisi mushonga wechirwere . Zvisinei, inogona kuderedza mwero wechirwere ichi. Izvi zvinoreva kuti inogona kubatsira murwere kuchengetedza ndangariro dzake uye kugona kwake kuita mabasa ezuva nezuva kwenguva yakareba.
Mushonga uyu unoshanda zvakadii?
Zvichienderana nemhedzisiro yemiedzo yekiriniki yakaburitswa gore rapfuura, kurapwa uku
kunogona kuderedza mwero wekuwedzera kwechirwere mukati memwedzi mishoma.Zvave zvichikwanisika. Izvi zvinoyerwa kuburikidza nemiedzo inoyera kugona kwepfungwa dzevarwere (semuenzaniso, kurangarira, kugadzirisa matambudziko) uye kuti vanoita mabasa ehupenyu hwezuva nezuva sei (semuenzaniso, kutyaira, kushandisa mari zvakanaka). Dzimwe nyanzvi dzinoti mhedzisiro iyi mhedzisiro iri nyore kana kuti "yakajairika". Izvi zvinoreva kuti haugone kutarisira mutsauko mukuru kubva pane izvi. Asi zvakanakawo kuti chirwere chinogona kudzikiswa mumwedzi mishomanana chete, pane kuti chiwedzere kuipa pasina kurapwa. Nezvenzira iyo kurapwa kunoitwa, mushonga uyu unopiwa kuvarwere mwedzi wega wega kuburikidza netsinga (infusion). Avo vakapinda mumiedzo iyi vakapihwa kurapwa uku kwegore nehafu.
Kune mabhenefiti pamwe nenjodzi dzakakomba.
Kufanana nemushonga upi zvawo une simba, donanemab ine mabhenefiti pamwe nemigumisiro yakakomba uye njodzi. Zvakakosha kunzwisisa mativi ese usati waita sarudzo.
| Mabhenefiti | Njodzi Nekushaikwa |
|---|
| Kuderedza mwero wechirwere ichi. | Migumisiro yakaipa: Pane njodzi yekuzvimba kweuropi kana kubuda ropa muuropi. |
| Kubatsira kuchengetedza ndangariro uye kugona kuita mabasa ezuva nezuva kwenguva yakareba. | Munguva yekuedzwa kwekiriniki, vanhu vatatu vakafa nekuda kwekurapwa uku vakashumwa. |
| Kutarisa ma plaque ari muuropi anokonzera chirwere ichi. | Mutengo wakakwira: Zvinoenderana nefungidziro dzeAmerica, mutengo wepagore wekurapwa unogona kusvika pamadhora zviuru zvitanhatu nemazana matanhatu ($6,600) (anenge mamiriyoni maviri erupi dzekuSri Lanka). |
| Kuunza tariro itsva kuvarwere vane Alzheimer nemhuri dzavo. | Kuuya kuchipatara mwedzi wega wega kunorapwa uye kubayiwa mushonga netsinga. |
Pasinei nezvose izvi, boka revanopa mazano reFDA rakazopedzisira rasarudza kuti
mabhenefiti emushonga uyu anopfuura njodzi dzawo.Kureva kuti, kana ikapihwa varwere vakakodzera, pasi pekutarisirwa kwakakodzera, mabhenefiti acho anokura.
Uyu ndiwo mushonga mutsva chete uripo here?
Kwete. Kune mumwe mushonga unoshanda nenzira yakafanana. Unonzi
lecanemab . Mushonga uyu unoshandawo nekutarisa maplatelet anoungana muuropi. Wakatenderwa neFDA muna Chikunguru 2023. Donanemab inhanho imwe murwendo irworwo. Masangano eAlzheimer's anotungamira pasi rose ane tariro huru yekurapa kutsva kwakadai. Vanoti, "Kana kurapwa kwakadai kuchibvumidzwa, mukana wevarwere vanokodzera kurapwa uku unowedzera. Kufambira mberi kuri kuitwa panyaya yekurapwa." Parizvino, mamiriyoni evanhu pasi rose vanotambura nechirwere cheAlzheimer's. Hakuchina nzira yekudzivirira kana kurapa chirwere ichi zvachose. Nokudaro, mishonga yakaita sedonanemab inhanho dzakakosha zvikuru murwendo irworwo rurefu.
Mharidzo Yekuenda Nayo Kumba
- Donanemab mushonga mutsva wava kuda kubvumidzwa kurapa chirwere cheAlzheimer's pakutanga .
- Izvi hazvigone kurapa chirwere ichi, asi zvinogona kuderedza mwero wekuti zviratidzo zvinoramba zvichiwedzera kwemwedzi mishoma .
- Pamwe chete nemabhenefiti ekurapwa uku, kunewo njodzi dzakakomba , dzakadai sekuzvimba kweuropi uye kubuda ropa .
- Sarudzo yekutora mushonga uyu kana kusatora inofanira kuitwa mushure mekukurukurirana kwakazara nachiremba wako nezvemamiriro emurwere nenjodzi dzake, uye mushure mekunyatsoongorora zvakanakira nezvakaipira.
- Zvakanaka kuziva nezvemishonga mitsva yakaita seiyi, asi iva nechokwadi chekutsvaga mazano kubva kuna chiremba ane hunyanzvi usati waita chero sarudzo.
Chirwere cheAlzheimer, donanemab, chirwere cheuropi, kurasikirwa nendangariro, dementia, mishonga mitsva, monoclonal antibody
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