Mabundu asinganzwisisike mupancreas? Ngatidzidzei nezve (Intraductal Papillary Mucinous Neoplasm - IPMN) nenzira iri nyore!

Chirwere ichi chine zita refu chii? Ungave uchishamisika kuti chii chinonzi `Intraductal Papillary Mucinous Neoplasm` kana `(IPMN)`. Zita racho ringanzwika serinotyisa uye rakaoma kunzwisisa, asi ngatirambei takariverenga. Iwe kana mumwe munhu waunoziva mungave makambonzwa nezvechirwere ichi. Saka, ngatiregei kutya toziva kuti chii chaizvo.

Chii chaizvo chinonzi `IPMN`?

Zvichitaurwa zviri nyore, IPMN ibundu rine mvura, kana kuti cyst, rinoumbwa mukati memigero yepancreas yako. Izvi hazvisi kenza chaiyo, asi vanachiremba vanozviona se "zvisina kukonzera kenza." Izvi zvinoreva kuti havasi kenza ikozvino, asi vanogona kuzova kenza mune ramangwana.

Funga nezvazvo, dzimwe nguva zvinoita semuti mudiki. Zvingave kana kuti kwete muti mukuru. Ndizvo zvakaita bundu iri rekuti '(IPMN)'. Vaongorori vanotenda kuti pakati pe20% ne30% yevanhu vanotambura nekenza yepancreas, kana vanhu vaviri kana vatatu pavanhu gumi, kenza iyi yakatanga se '(IPMN)'. Vamwe vanhu vanogona kuva nebundu iri kwemakore vasingaratidze zviratidzo. '(IPMN)' inorapwa nekuvhiyiwa, kana nekunyatsoongororwa kwenguva yakareba.

Ko `IPMN` inogara iri kenza here?

Kwete, havasi vese vane IPMN vanova negomarara . Ndicho chinhu chekutanga chaunofanira kunzwisisa. Zvisinei, vamwe vanogona kuzopedzisira vava pancreatic ductal adenocarcinoma (PDAC). PDAC ndiyo mhando inonyanya kuzivikanwa yegomarara regomarara. Gomarara regomarara igomarara risingawanzoitiki. Rinoumba 3% yegomarara rese muUnited States. Zvisinei, gomarara regomarara rinoumba 7% yegomarara rese. Zvinosuwisa kuti hariwanzoonekwa nekukurumidza, apo kurapwa kunogona kushanda zvakanaka.

Ndiani anonyanya kukanganiswa nemamiriro ezvinhu aya?

Zvakaoma kuti vanachiremba vataure kuti vangani chaizvo vane bundu iri, nekuti kazhinji harikonzeri zviratidzo uye harionekwi. Zvisinei, zvidzidzo zvakaratidza kuti rinonyanya kuitika muvarume vari pakati pemakore makumi mashanu nemakumi manomwe .

Chii chinoitika kumuviri ne `(IPMN)` iyi?

MaIPMN ane mvura yakakora yakaita sejelly mukati. Vanachiremba vanoti mucin. Kana mabundu aya asina kenza anotanga kushanduka kuita kenza, anotanga kuburitsa mvura iyi inonzi mucin yakawanda. Funga nezvayo sebharumu diki rinozadzwa nemvura. Kana mucin iyi yaungana, inogona kuvhara ducts dzepancreas mupancreas yako. Idzi ducts madiki anobatsira kugaya chikafu. Kana dzavharika, zvinogona kukonzera kuzvimba kwepancreas (pancreatitis) .Izvi zvinogona kuva chirwere chinorwadza zvikuru. Dzimwe nguva kuzvimba kwepancreas ndicho chiratidzo chekutanga cheIPMN.

Ndezvipi zviratidzo zveIPMN?

Vanhu vazhinji vane chirwere ichi havanzwi kurwara kana kuti vane zviratidzo zvakasiyana. Ndiro dambudziko riripo panyaya iyi. Kazhinji, rudzi urwu rwegomarara runowanikwa netsaona pavanenge vachiongororwa chimwe chirwere. Zvisinei, vamwe vanhu vanogona kuona zviratidzo zvakaita se:

• Kurwadziwa kwemudumbu nguva nenguva: Vamwe vanhu vanogona kurwadziwa mudumbu mushure mekudya. Izvi zvinogonawo kukonzera kurasikirwa nechido chekudya.
• Kudzikira uremu kusingatarisirwi: Kana ukadzikira uremu usingaedze, ichocho chiratidzowo.
• Kusvotwa nekurutsa.
• Kurwadziwa kwemusana.
• Tsvina/tsvina ine mafuta: Kana tsvina ichiita seine mafuta.

Dzimwe nguva, bundu iri rinogona kukonzera zviratidzo zvakafanana nezvimwe zvirwere. Semuenzaniso:

• Jaundice: Kutsvuka kweganda nekuda kwekuvharika kwenzira dzemudumbu.
• Chirwere cheshuga chichangobva kutanga: Kuwanda kweshuga muropa nekuda kwekukuvadzwa kwepancreas pachayo.
• Pancreatitis: Chirwere chinokonzerwa nekuvharika kwenzira dzemudumbu.

Chii chinokonzera IPMN?

Vaongorori vanotenda kuti maIPMN anokura kana paine shanduko (kuchinja) mumajini anodzora kukura kwemasero edu kana kudzivirira bundu kuti risaumbe. Izvi zvinoreva kuti mamwe masisitimu ekudzivirira emuviri wedu anoshaya simba. Kana mumwe munhu mumhuri akambova nekenza yepancreatic (PDAC) , vamwe vemumhuri iyoyo vari panjodzi huru yekuva neIPMN.

Vanachiremba vanoona sei izvi?

Vanachiremba vanoshandisa bvunzo dzakasiyana-siyana dze `(imaging)` kuti vaongorore `(IPMN)`. Panyaya idzi, bvunzo yakakosha inonzi `Magnetic Resonance Cholangiopancreatography (MRCP)` inokosha zvikuru. Iyi bvunzo inoshandisa muchina we `(MRI)`. Izvi zvinogona kutora mifananidzo yakajeka yechiropa chako, ducts dze bile, gallbladder, pancreas, uye ducts dzepancreatic. Vanachiremba vanoshandisa bvunzo iyi kuti vaone kana paine shanduko dziri muducts dzepancreatic.

Mabundu aya e "(IPMN)" akakamurwa kuita mhando nhatu huru:

• Rudzi rwematumbu makuru (MD-IPMN): Aya mabundu anovhara duct huru yepancreas yako. Izvi zvinogona kukonzera kuti duct huru ikure, kana kuti ikure. Upamhi hweduct huru hunowanzova mamirimita 3.5. Kana yakakura kupfuura mamirimita mashanu, inogona kunge iri chiratidzo chekuti ine mukana wekuva nekenza.
• Rudzi rwemapazi emugero (BD-IPMN): Aya mabundu anoumbwa mumapazi madiki akaita semapazi anobuda kubva pamugero mukuru. Mabundu aya anowanzova asina njodzi .
• Mhando dzakasiyana-siyana (MT-IPMN): Aya mabundu anokura mumigero mikuru uye yebazi repancreas.

Pane mimwe miedzo yekuongorora `IPMN` here?

Ehe, kune mimwe miedzo. Vanachiremba vanogonawo kuita bvunzo inonzi Endoscopic Ultrasound (EUS). Izvi zvinogona kutora mifananidzo yakajeka yepancreas nebundu. Munguva yebvunzo iyi, sampuli diki yebundu, inonzi Fine-Needle Aspiration (FNA), inogona kutorwa (biopsy). Muenzaniso wacho unozoongororwa uchishandisa maikorosikopu kuti uone rudzi rwemasero (dysplasia) (kana masero acho achitaridzika asina kujairika) uye kuongororwa kwemajini kuti uone njodzi yekuti rive nekenza.

Chii chinonzi `Dysplasia`? Nei ichikosha?

"Dysplasia" zvinongoreva kuti masero ako anoita seasina kujairika kana akatariswa nemaikorosikopu.

• "High-grade dysplasia" zvinoreva kuti masero ako akafanana nemasero ekenza kupfuura masero ane hutano. Izvi zvinoreva kuti njodzi yacho yakakura.
• Kusashanda zvakanaka kwemasero (low-grade dysplasia) zvinoreva kuti mamwe masero anoita semasero ekenza, asi njodzi yekuti kenza ikure inofungidzirwa kuti yakaderera.

Vanachiremba vanoshandisa ruzivo nezvechirwere (dysplasia) uye ruzivo rwemajini egomarara iri kuti vagadzire maIPMN muzvikamu zvina zvikuru. Iyi inyaya yakadzama, asi ndichaichengeta iri nyore:

1. MaIPMN erudzi rwemudumbu: Anowanzo buda mumigero yemapazi epancreas. Anowanzova nedysplasia yemhando yepasi. Vanhu vanopfuura 90% vane rudzi urwu rwebundu vanorarama makore gumi mushure mekuonekwa kuti vane chirwere ichi.

2. MaIPMN erudzi rwemudumbu: Aya anogona kuwanikwa mumigero mikuru uye yemapazi epancreas. Anogona kunge aine dysplasia yepamusoro uye anogona kuzopedzisira ava kenza yepancreas. Vanhu vanosvika 70% vane rudzi urwu rwebundu vanorarama makore mashanu mushure mekuonekwa kuti vane chirwere ichi. Chikamu ichi chinoderera kusvika 50% nemakore gumi.

3. MaIPMN erudzi rwePancreatobiliary: Aya anowanikwawo mumachubhu makuru nebazi, uye ane dysplasia yepamusoro. Vanhu vanosvika 80% vane rudzi urwu rwebundu vanogona kuwana kenza yepancreas inopararira.

4. MaIPMN erudzi rweOncocytic: Aya ndiwo mhando yegomarara risingawanzoitiki. Rinokura mugwara guru repancreas uye rine dysplasia yepamusoro. Vanhu vanosvika hafu yerudzi urwu rwegomarara vanozorwara negomarara repancreas.

Zvakakosha: Usavhunduke nemapoka aya nenhamba. Aya mashoko chete. Chiremba wako chete ndiye anogona kukuudza chaizvo kuti chirwere chako chakaita sei.

Mishonga yeIPMN inorapwa sei?

Kana IPMN ichionekwa seine njodzi shoma , vanachiremba vanowanzokurudzira kuti bundu rirambe richitariswa zvakanyanya.Izvi zvinodaro nekuti bundu zhinji dzisina njodzi (IPMN) hadziite kenza. Zvisinei, kana uine bundu riri mugwara guru repancreas yako, zvinoreva kuti uri panjodzi yakakura zvishoma, chiremba wako anogona kukurudzira kuvhiyiwa kuti bundu ribviswe . Heano mimwe mienzaniso:

• Kuvhiyiwa kweDistal Pancreatectomy: Izvi zvinosanganisira kubvisa muswe uye/kana muviri wepancreas. Kuvhiyiwa uku kunoitwa kana paine bundu mumigero mikuru munzvimbo iyoyo.
• Kubviswa kwepancreat rese: Izvi zvinosanganisira kubviswa kwepancreat yese, gallbladder, common bile duct, zvikamu zvedumbu neura hudiki, uye kazhinji chirwatata. Uku kuvhiyiwa kukuru.
• Maitiro eWhipple (pancreaticoduodenectomy): Kuvhiyiwa uku kunogona kukurudzirwa pamabundu ari mumigero mikuru yemusoro wepancreas (nzvimbo yakakura panenge paine pancreas inosangana neura hudiki). Kunosanganisira kubvisa musoro wepancreas, chikamu chekutanga cheura hudiki (duodenum), gallbladder, chikamu chemugero we bile, uye lymph nodes dziri pedyo.

Ndezvipi zvinetso zvinogona kuitika nekuda kwekuvhiyiwa uku?

Sekunge kune chero kuvhiyiwa kukuru, pane matambudziko anogona kuitika. Haasi mamiriro evanhu vese akafanana. Saka, zvakanaka kubvunza chiremba wako nezvematambudziko chaiwo aungasangana nawo.

Zvinotora nguva yakareba sei kuti munhu apore mushure mekuvhiyiwa kwakadai?

Izvi zvinosiyana kubva pamunhu nemunhu. Zvisinei, vanhu vazhinji vanofanirwa kugara muchipatara kwemazuva mashoma mushure mekuvhiyiwa kwepancreas. Zvinogona kutora mavhiki kana mwedzi kuti vapore zvizere.

Ndinofanira kurapwa nechemotherapy kana radiation mushure mekuvhiyiwa here?

Dzimwe ongororo dzakaratidza kuti chemotherapy uye/kana radiation therapy zvinogona kubatsira mushure mekuvhiyiwa. Zvisinei, unofanirawo kufunga nezvemigumisiro yemishonga iyi. Dzimwe nguva migumisiro inogona kupfuura mabhenefiti emishonga iyi. Bvunza chiremba wako kuti akupe rumwe ruzivo nezveizvi.

Chiremba wangu akati ndiongorore `IPMN`. Izvi zvinorevei?

Izvi zvinoreva kuti bvunzo dzako dzakaratidza kuti IPMN yako haina njodzi uye haingangove nekenza. Vanachiremba vacharamba vachitarisa bundu iri risina njodzi vachishandisa bvunzo dzemifananidzo (dzakadai seMRCP). Izvi zvinoreva kuti, "Ngatirambei tichitarisa izvi toona kana paine chinochinja."

Ndingaitei kuti ndideredze njodzi yangu yekubatwa neIPMN?

Vaongorori vanotenda kuti bundu iri rinokonzerwa nekuchinja kwemajini. Saka, hapana chaunogona kuita kudzivirira IPMN kuti isakure. Zvisinei, zvinotevera zvinogona kubatsira kuderedza njodzi yako yese yekenza yepancreas uye kukubatsira kuongorora njodzi yako yeIPMN:

• Dzidza nezvenhoroondo yehutano hwemhuri yako.Kana mumwe munhu mumhuri yako akambova nekenza yepancreas (PDAC), uri panjodzi huru yekubatwa neIPMN.
• Kenza yepancreatic inobatanidzwa nekusvuta. Kana ukashandisa fodya (fodya, beedis, fodya), edza kurega.
• Deredza kunwa doro, kana kuti rega zvachose.
• Edza kuchengetedza huremu hwakanaka.
• Edza kudzivirira chirwere cheshuga cherudzi rwechipiri nekudya zvine hutano uye kurovedza muviri. Kana uine chirwere cheshuga, shanda nachiremba wako kuti udzore huwandu hweshuga muropa rako.

Ungagara kwenguva yakareba sei uine IPMN?

Sezvakaita chero kenza, kuongororwa nekukurumidza uye kurapwa ndizvo zvinhu zvakakosha pakuona kuti munhu ararama sei. Kazhinji, vanhu vanosvika 95% vanoonekwa uye vanorapwa IPMN isati yatanga kuita kenza yepancreatic vachiri vapenyu makore mashanu mushure mekuonekwa. Kana uine mibvunzo nezvechirwere chako, chiremba wako ndiye akanakisa pakupa ruzivo.

Ndine IPMN isina njodzi. Ndingazvitarisira sei?

Kazhinji, mapundu aya haaite kenza. Zvisinei, zvakajairika kunzwa kushushikana uye kuzvidya mwoyo nekuda kwepfungwa yekuti, "Zvichida zvinogona kudaro." Kana uchinzwa seizvi, taura nachiremba wako nezvazvo. Iye/iye achakutsanangurira kuti sei uri panjodzi shoma yekubatwa nekenza yepancreas. Iye/iye achakupawo mazano ezvinhu zvaunogona kuita kuti uderedze njodzi yako yese yekubatwa nekenza yepancreas.

Intraductal Papillary Mucinous Neoplasm (IPMN) izita refu, dzimwe nguva rinovhiringidza rebundu rinoumbwa mumapaipi epancreas uye rinogona kuva kenza yepancreas. Bundu iri hariwanzo kukonzera zviratidzo uye rinowanzoonekwa netsaona panguva yekuongororwa kunoitwa zvimwe zvikonzero.

Kana chiremba wako akakuudza kuti une IPMN, ungashamisika. Asi yeuka, kuva nechirwere ichi hazvirevi kuti uchava nekenza zvechokwadi. Kazhinji, mimwe miedzo inoratidza kuti bundu harisi kenza (risina kuipa). Kana bundu rako risiri kenza, chiremba wako acharamba achiritarisa kuti aone kana riri pangozi huru kana kuti kenza. Uye, chakakosha ndechekuti, kunyangwe bundu rako rikawanikwa riri pangozi huru, vanhu vanosvika 95% vakaongororwa neIPMN uye vakarapwa vasati vava kenza vachiri vapenyu makore mashanu mushure mekuonekwa.

Chero mamiriro ako ezvinhu, pane zvaunogona kuita kuti uderedze njodzi yako yekubatwa nekenza yepancreas. Taura nachiremba wako nezveizvi. Achafara kukubatsira.

Pakupedzisira, zvinhu zvekurangarira (Mharidzo Yekuenda Kumba)

Zvakanaka, saka ndinovimba wava kunzwisisa zviri nani zvatanga tichitaura nezvazvo, ``(IPMN)``. Kunyangwe iyi iri nyaya yakaoma zvishoma, ngatiedzei kuinzwisisa zviri nyore.

• IPMN ibundu rinokura mumapaipi epancreas uye rinogona kuita kenza. Havasi vese vanozoita kenza.
• Kazhinji, hairatidzi zviratidzo uye inowanikwa netsaona panguva yekuedzwa kumwe.
• Chirwere ichi chinoonekwa kuburikidza nemiedzo yakaita se `(MRCP)` uye `(EUS)`.
• Kurapa kunogona kusanganisira kuongororwa kana kuvhiyiwa , zvichienderana nerudzi uye kuoma kwebundu racho.
• Kuonekwa nekukurumidza uye kurapwa ndizvo zvinonyanya kukosha.
• Usatya kana ukaudzwa kuti une IPMN. Taura nachiremba wako wosarudza nzira yakanakisisa yekurapa mamiriro ako ezvinhu.
• Fungawo nezvekuchinja mararamiro (kurega kusvuta, kuchengetedza huremu hwakanaka, nezvimwewo) izvo zvinogona kuderedza njodzi yekenza yepancreas.

Kana muine mimwe mibvunzo nezveizvi, musazeza kubvunza chiremba wenyu. Rambai muine hutano hwakanaka!

Pancreas , IPMN, Kenza, Kenza yePancreatic, Bundu, Zviratidzo, Kurapwa