Unoziva nezve 'cholesterol yakavanzika' iyi here? Ngatidzidzei nezve Lipoprotein (a)!

Paunoongororwa ropa rako kuti une cholesterol here, pamwe wakaona mazita akaita seLDL, HDL, uye triglycerides mumushumo waunowana, handiti? Tinowanzo taura nezve "cholesterol yakanaka" (HDL) uye "cholesterol yakaipa" (LDL). Asi pane imwe isiri pane rondedzero iyo munhu wese anotaura nezvayo, yakavanzwa zvishoma, asi inogona kukanganisa hutano hwemwoyo. Ndiyo Lipoprotein (a) , kana kuti Lp(a) muchidimbu. Zvakafanana nechakavanzika chemhuri, uye dzimwe nguva tinogona kukonzera matambudziko makuru mumiviri yedu tisingazive.

Zvichitaurwa zviri nyore, chii chinonzi Lipoprotein (a)?

Zvakanaka, ngatizvitaure seizvi. Lipoprotein (a) rudzi rweLDL (Low-Density Lipoprotein), inozivikanwawo se "cholesterol yakaipa." Chii chinoitika kana cholesterol yeLDL ikawedzera mumuviri? Inoungana pamadziro etsinga dzedu dzeropa, ichigadzira maplaque akafanana nemabumps ekukurumidza mumugwagwa. Mukurapa, tinodana izvi kuti plaque . Sezvo mabumps aya ekukurumidza achiungana, ropa rinova risingachakwanisi kuyerera zvakanaka. Pakupedzisira, izvi zvinogona kuvhara mitsipa yeropa zvachose uye kumisa kuyerera kweropa. Ichi ndicho chikonzero chikuru chekurohwa nemoyo uye sitiroko.

Zvino, chinhu chakakosha nezve Lp(a) ndechekuti yakakomba zvishoma kupfuura LDL. Pane zvikonzero zviviri zveizvozvo:

1. Kugwamba kweropa nekukurumidza: Zvidimbu zveLp(a) zvinobatsira kuti ropa redu rigwambe nekukurumidza kupfuura zvakajairika.

2. Inomisa kupwanyika kweropa: Inodzivirirawo kupwanyika kweropa rakaumbwa.

Fungidzira, jira recholesterol (plaque) raumbwa mukati metsinga yeropa. Kana jira iroro rikabvaruka nekuda kweLp(a), pane mukana mukuru wekuti ropa ridzike nekukasika uye rivhare zvachose tsinga yeropa. Ndosaka tichifanira kungwarira zvikuru nezveLp(a).

Ko Lp(a) level chinhu chinobva mumajini here?

Ehe. Ndizvozvo. Ichi ndicho chinhu chakakosha uye pamwe chinosuwisa zvishoma nezveizvi. Lp(a) level yako inotsanangurwa nemajini aunowana kubva kuna amai vako nababa vako. Izvi zvinoreva kuti zvisinei nekuti unoita maekisesaizi akawanda sei kana kuti unodzora sei kudya kwako, haugone kuderedza zvakanyanya Lp(a) level yako. Lp(a) level yauinayo paunenge uchiri mudiki ingangove yako kweupenyu hwako hwese.

Ndingaziva sei mazinga angu eLp(a)?

Izvi zvinogona kuonekwa nekuongororwa ropa kuri nyore. Asi pane kanhu kadiki pano. Kazhinji unoongororwa cholesterol, inonzi Lipid Profile.Kutaura zvazviri, huwandu uhwu hweLp(a) hahupimwe. Hunofanira kuitwa hwakasiyana, kunyanya nekukumbira. Chiremba wako anogona kusarudza kana uchida uye okutumira kuti uwane.

Sei chiremba angakurudzira bvunzo iyi?

Havasi vese vanoda bvunzo iyi, asi kana muine zvimwe zvinhu zvinowedzera njodzi yenyu yechirwere chemwoyo, chiremba wenyu anogona kusarudza kuongorora izvi zvakare.

mazinga eLp(a) uye zvazvinoreva

Kune nzira mbiri dzekuyera mazinga eLp(a). Imwe ndeyekuyera huremu hweLp(a) muropa. Huremu hwacho hunopiwa mumamirigiramu pa deciliter (mg/dL). Imwe ndeyekuyera huwandu hwezvidimbu zveLp(a) muropa. Huremu hwacho hunowanikwa muma nanomoles pa litre (nmol/L). Zvakakosha kubvunza chiremba wako kuti mushumo wako uri muzvikamu zvipi.

Kazhinji tinowanzo patsanura huwandu hwe mg/dL seizvi:

• Mwero wakajairika: Pasi pe30 mg/dL.
• Njodzi yemuganhu: Pakati pe30 mg/dL ne50 mg/dL.
• Njodzi huru: Inopfuura 50 mg/dL.

Mu nmol/L, kukosha kuri pamusoro pe 100 nmol/L kunoonekwa sekuti kune njodzi huru.

Kuwanda kweLp(a) yako kunoreva kuti uri panjodzi huru yekubatwa nechirwere chemwoyo nechirwere chetsinga dzeropa, kunyangwe kana mamwe mafuta ako eropa ari akanaka.

Tsvakurudzo yakawana kuti mazinga eLp(a) akakwirira akabatana zvakananga nezvirwere izvi:

• Chirwere chemwoyo
• Kumira kurova kwemoyo
• Kurohwa
• Stenosis yevharuvhu yeaorta
• Chirwere chetsinga dzemutsinga (PAD)

Pane zviratidzo zvemazinga eLp(a) akakwira here?

Kwete. Ndiyo nyaya inotyisa. Vanhu vazhinji vane Lp(a) levels yakakwira havaratidzi zviratidzo. Havazivi kuti vari panjodzi kusvika chimwe chinhu chakakomba senge chirwere chemwoyo chaitika. Ndosaka, kana uine nhoroondo yemhuri yechirwere chemwoyo, zvakakosha kutaura nachiremba wako nezvazvo nekukurumidza uye kuongororwa kana zvichidikanwa.

Zvakanaka, zvino tingaderedza sei Lp(a) iyi?

Uyu mubvunzo une munhu wese. Kutaura chokwadi, pari zvino hapana mushonga chaiwo wakabvumidzwa kunanga nekudzikisa huwandu hweLp(a). Vatsvaguri vari kugadzira nekuyedza mishonga mitsva yakati wandei yechinangwa ichi. Saka tinotarisira kuti mhinduro yakanaka ichawanikwa munguva pfupi iri kutevera.

Kunyangwe tisingakwanise kudzikisa zvakananga huwandu hweLp(a), chinhu chakanakisa chatingaita ndechekudzora zvimwe zvinhu zvese zvinowedzera njodzi yechirwere chemwoyo. Nemamwe mashoko, kana Lp(a) iriyo yega pfuti yatinayo, zvakafanana nekudzima zvimwe zvese.

Zvinhu zvaunogona kuita:

• Rega kushandisa fodya zvachose. Kusvuta ndicho chinhu chikuru chinokonzera kukuvara kwetsinga dzeropa.
• Rovedza muviri nguva dzose. Ita chimwe chinhu chakadai sekufamba kana kumhanya kwemaminitsi makumi matatu kwemazuva mashanu pasvondo.
• Ramba uine huremu hwakanaka.
• Dzorera kudya kunovaka muviri. Idya mafuta mashoma, munyu, neshuga shoma, uye miriwo yakawanda, michero, miriwo, uye chikafu chine faibha yakawanda.
• Chengetedza BP yako nechirwere cheshuga zviri pasi pesimba rako. Shandisa mishonga yawakanyorerwa nachiremba weizvi.
• Dzora huwandu hwecholesterol yeLDL. Kunyangwe zvisingaite kuderedza Lp(a), mishonga inoderedza cholesterol yeLDL, senge statins kana PCSK9 inhibitors , inogona kuderedza zvakanyanya njodzi yese.
• Dzora kushushikana.

Zvichienderana nenjodzi yako, chiremba wako anogona kukupa mushonga wakaita seaspirin wekuderedza kugwinya kweropa.

Kune avo vane huwandu hwakanyanya hweLp(a), kunyanya avo vane Familyal Hypercholesterolemia, kune mushonga unonzi Apheresis . Izvi zvakafanana nedialysis kana itsvo dzisisina kushanda. Wakabatana nemuchina uye zvidimbu zveLp(a) zvinoseferwa kubva muropa. Zvisinei, uyu mushonga unotora maawa akati wandei, unofanirwa kuitwa kamwe chete kana kaviri pasvondo, uye unongoitirwa varwere vakakosha chete.