Unonzwa sekuti une testosterone shoma here? Ngatidzidzei chaizvo nezvekuchinja uku mumuviri wemurume (Male Hypogonadism)!

Dzimwe nguva unonzwa kuneta, kusafarira chero chinhu, kana kuti une mubvunzo mudiki nezvezvimwe zvinhu zvine chekuita nehurume here? Pamwe chikonzero cheizvi kudzikira kwehomoni ye testosterone mumuviri wako. Nhasi, tichataura nezvekudzikira uku kwemazinga e testosterone , kana sekudanwa kwazvinoitwa navanachiremba, chirwere chinonzi Male Hypogonadism . Usazvidya moyo, ichi chinhu chinogona kuitika kuvanhu vazhinji, uye kune mishonga yacho.

Zvinorevei kuti testosterone yakaderera?

Zvichitaurwa zviri nyore, testosterone shoma zvinoreva kuti machende ako (magland anogadzira urume muvarume) haasi kugadzira testosterone yakakwana. Kutaura chokwadi, testosterone iyi inogadzirwa nemasero eLeydig ari mukati memachende.

Chirwere ichi chinogona kuoneka nezviratidzo zvakasiyana pamazera akasiyana. Uyewo, huwandu hwe testosterone hunodzikira zvishoma varume vachikura. Izvi zvinodanwa nemamwe mazita, semuenzaniso:

• Chirwere chekushaya testosterone
• Kushomeka kweTestosterone
• Kusagona kwepabonde kwekutanga
• Hypogonadism yechipiri

Sei testosterone ichikosha zvakadaro?

Testosterone ndiyo homoni yevarume inonyanya kukosha. Inokosha pakukura kwehunhu hwevarume uye kugadzirwa kwembeu (spermatogenesis). Varume vane testosterone yakawanda kwazvo mumiviri yavo kupfuura vakadzi.

Testosterone inobatsira kuchengetedza nekugadzira zvinhu izvi mumuviri wemurume:

• Nhengo dzepabonde
• Kukura kwetsandanyama
• Mwero wemasero matsvuku eropa ane hutano
• Kuwanda kwemapfupa
• Hutano hwakanaka hwepfungwa
• Basa repabonde uye rekubereka

Kazhinji, miviri yedu inotonga huwandu hwe testosterone muropa redu. Hunokwira mangwanani uye hunoderera zvishoma nezvishoma sezvo zuva richienderera mberi.

Hypothalamus ne pituitary gland muuropi hwako zvinodzora huwandu hwe testosterone inoburitswa uye inoburitswa nemachende ako.

Hypothalamus inoburitsa gonadotropin-releasing hormone (GnRH) . Izvi zvinopa chiratidzo kune pituitary gland kuti iburitse luteinizing hormone (LH) . LH inobva yaenda kumachende kuti ikurumidzise kugadzirwa kwe testosterone. Pituitary gland inoburitsawo follicle-stimulating hormone (FSH) kuti ibatsire kugadzira mbeu.

Saka, kana paine dambudziko nematesticles ako, hypothalamus, kana pituitary gland, huwandu hwe testosterone yako hunogona kudzikira.

Ndeupi mwero unoonekwa se "testosterone yakaderera"?

Sekureva kweAmerican Urology Association (AUA), mwero we testosterone muropa remunhu mukuru unoonekwa sewakaderera kana uri pasi pe300 nanograms pa deciliter (300 ng/dL).

Zvisinei, vamwe vaongorori navanachiremba havabvumirani zvizere nepfungwa iyi. Vamwe vanotenda kuti chero chinhu chiri pasi pe `250 ng/dL` chinoonekwa sechakaderera. Zvisinei, vanachiremba vachanyatso funga nezvezviratidzo zvako pavanenge vachiona kana une testosterone shoma.

Ndiani ari panjodzi huru yekuderera kwe testosterone uku?

Chirwere ichi chinogona kubata varume vezera ripi zvaro, kubva pakuzvarwa kusvika pakuva munhu mukuru.

Zvisinei, vanhu ava vane mukana wekuva ne testosterone yakaderera:

• Kune vanhu vakuru
• Kune vanhu vakafuta zvakanyanya (vane mafuta akawandisa)
• Kune vanhu vane chirwere cheshuga cherudzi rwechipiri chisina kudzorwa zvakanaka
• Kune avo vane sleep apnea inodzivisa kurara
• Vanhu vane zvirwere zvisingaperi zvakaita sekutadza kushanda kweitsvo uye cirrhosis yechiropa
• Kune avo vanorarama neHIV/AIDS

Dambudziko iri rakajairika zvakadii?

Zvakaoma kuti vaongorori vataure kuti testosterone yakaderera yakajairika sei, nekuti zvidzidzo zvakasiyana zvakatsanangura "testosterone yakaderera" zvakasiyana.

Zvichienderana nedzimwe data, varume vanosvika 2% vanogona kunge vaine chirwere ichi. Dzimwe ongororo dzinoratidza kuti varume vanopfuura 8% vari pakati pemakore makumi mashanu nemakumi manomwe nemapfumbamwe vane testosterone yakaderera.

Ndezvipi zviratidzo zve testosterone yakaderera?

Zviratidzo zve testosterone yakaderera zvinogona kusiyana zvikuru kubva pamunhu kuenda kumunhu, kunyanya zvichienderana nezera.

Zviratidzo muvarume vakuru

Kana uine zviratidzo izvi, pane mukana mukuru wekuti testosterone yako ishoma:

• Kuderera kwechido chepabonde
• Kusashanda zvakanaka kwenhengo dzesikarudzi
• Kudonha kwebvudzi muhapwa nenzvimbo dzakavanzika
• Kudzikira kwemachende
• Kupisa kunopisa
• Kuderera kana kusavapo kwehuwandu hwembeu (Azoospermia), izvo zvinogona kukonzera matambudziko pakubata pamuviri kwemwana.

Zvimwe zviratidzo zvinogona kusanganisira:

• Kushungurudzika (chirwere chepfungwa)
• Kuomerwa nekuisa pfungwa pachinhu chimwe chete uye kuyeuka
• Kuwedzera kwemafuta emuviri
• Kukura kwemazamu evarume (Gynecomastia)
• Kuderera kwesimba remhasuru nehukuru
• Kuderera kwekutsungirira kwemuviri

Zviratidzo muvana (vasati vasvika kana kuti panguva yekuyaruka)

Kana huwandu hwe testosterone mumwana wemukomana hukadzikira asati asvika kana kuti panguva yekuyaruka, anogona kuona zviratidzo zvakaita se:

• Kukura kwehurefu kunononoka, asi makumbo anogona kukura kwenguva yakareba zvisina kuenzana kupfuura dzimwe nhengo dzemuviri.
• Kukura kwebvudzi kwakaderera munzvimbo yakavanzika.
• Kukura kwemachende nemachende kwakadzikira.
• Kudzikira kwekudzikira kwezwi.
• Kuderera kwesimba uye kutsungirira kunokonzerwa nezera.

Ndezvipi zvikonzero zve testosterone yakaderera?

Pane zvikonzero zvakawanda zvinoita kuti huwandu hwe testosterone hudzikire. Dambudziko iri rinowira muzvikamu zviviri zvikuru:

1. Kusagona kwepabonde: Izvi zvinokonzerwa nedambudziko remachende pachawo.

2. Kusagona kwemuviri kwechipiri: Izvi zvinokonzerwa nekusashanda zvakanaka kwegland repituitary kana hypothalamus muuropi.

Mhando idzi dzese dzinogona kukonzerwa nezvikonzero zvekuzvarwa nazvo kana kuti zvikonzero zvinowanikwa zvinozoitika gare gare (muhudiki kana kuti muhukuru).

Zvinokonzera hypogonadism yekutanga

Chinoitika munyaya iyi ndechekuti pane dambudziko nemachende, izvo zvinoadzivisa kugadzira testosterone zvakanaka.

Rimwe zita reizvi ihypergonadotropic hypogonadism . Apa ndipo apo pituitary gland inoburitsa mahormone akawanda eLH neFSH (anozivikanwawo segonadotropins) nekuda kwe testosterone shoma. Kazhinji, kana mahormone aya akakwira, machende anoudzwa kuti agadzire testosterone nembeu yakawanda. Zvisinei, kana machende akakuvara (kazhinji nekuda kwechemotherapy yekenza) kana kana machende asipo, haagone kupindura kune magonadotropin aya akawedzera. Nekuda kweizvozvo, testosterone nembeu zvishoma kwazvo zvinogadzirwa kana kusavapo.

Dzimwe nguva mu hypogonadism yekutanga, mazinga e gonadotropin anogona kukwidziridzwa kunyangwe mazinga e testosterone ari mukati mehuwandu hwakajairika. Nyanzvi yako ichakutsanangurira izvi uye kana kurapwa kuchidikanwa kunyangwe testosterone iri yakajairika.

Zvikonzero zvekuzvarwa nazvo:

• Kusavapo kwemachende panguva yekuzvarwa (Anorchia)
• Cryptorchidism (kutadza kwemasero kuburuka kubva paganda remwana)
• Kusagadzirwa kwakakwana kwemasero eLeydig mumachende (Leydig cell hypoplasia)
• Klinefelter's syndrome (varume vanozvarwa vaine imwe chromosome X pane XY - XXY)
• Noonan syndrome (chirwere chemajini chisingawanzoitiki, chinogona kukonzera kunonoka kuyaruka, machende asina kusimba, kana kushaya mbereko)
• Myotonic dystrophy (boka rezvirwere zvekushaya simba kwetsandanyama zvakagarwa nhaka)

Zvikonzero Zvakawanikwa:

• Kukuvara kana kubviswa kwemachende.
• Kuzvimba kwechende rimwe chete kana ese ari maviri (orchitis). Izvi zvinowanzokonzerwa nehutachiona hwebhakitiriya (semuenzaniso hutachiona hwepabonde), kana kuti zvinogonawo kukonzerwa nehutachiona hwakadai semapundu.
• Kurapwa machende nechemotherapy kana nemwaranzi.
• Mamwe marudzi egomarara.
• Kushandiswa kweAnabolic steroid.

Zvinokonzera hypogonadism yechipiri

Kusagona zvakanaka kwemuviri kunokonzerwa nemamiriro ezvinhu anokanganisa mashandiro ehypothalamus uye/kana pituitary gland. Izvi zvinonzi hypogonadotropic hypogonadism.Inonziwo "testosterone yakaderera" nekuti huwandu hwemahormone ekuti `LH` ne`FSH` hwakaderera pano. Hunhu uhwu hwakaderera hunokonzera kudzikira kwekugadzirwa kwetestosterone nembeu.

Zvikonzero zvekuzvarwa nazvo:

• Hypogonadotropic hypogonadism iri yoga (mazinga eGnRH akaderera kubva pakuzvarwa)
• Kallmann syndrome (chirwere chemajini chisingawanzoitiki, kutadza kugadzira masero etsinga mu hypothalamus anogadzira GnRH. Kurasikirwa nekunhuhwirira kunogonawo kuitika)
• Prader-Willi syndrome (chirwere chisingawanzoitiki chemajini akawanda chinogona kukanganisa mashandiro ehypothalamus)

Zvikonzero Zvakawanikwa:

• Hypopituitarism (izvi zvinogona kukonzerwa nebundu repituitary (adenoma), hutachiona, kukuvara, kurapwa nemwaranzi, kana kuvhiyiwa)
• Hyperprolactinemia (kuwedzera kwemazinga eprolactin muropa)
• Kuwanda kwesimbi mumuviri (Hemochromatosis)
• Kukuvara kwehuropi kana musoro
• Chirwere cheCushing
• Kurwara kwechiropa
• Kukundikana kweitsvo
• HIV/AIDS
• Dambudziko rekushandisa doro
• Chirwere cheshuga chisingadzoreki zvakanaka
• Kufuta zvakanyanya (kuva nemafuta akawandisa)
• Kumbomira kufema pakurara
• Mimwe mishonga (semuenzaniso estrogen, mishonga inochinja mafungiro, metoclopramide, opioids, mimwe mishonga yekenza yeprostate)

Kunonoka kwe hypogonadism (LOH) rudzi rwe hypogonadism yechipiri inoitika nekukwegura kwakajairika. Varume pavanokura, kugadzirwa kwe testosterone uye/kana mbeu kunoderera nekuda kwekusashanda zvakanaka kwe hypothalamic-pituitary uye kushanda kwemasero eLeydig.

LOH uye testosterone yakaderera zvakajairika pakati pevarume vane chirwere cheshuga cherudzi rwechipiri, vakafuta zvakanyanya, uye/kana kufutisa.

Mune imwe ongororo, 30% yevarume vakafuta vaiva nemazinga e testosterone akaderera, zvichienzaniswa ne6% chete yevarume vane huremu hwakajairwa. Mune imwe ongororo, 25% yevarume vane chirwere cheshuga cherudzi rwechipiri vaiva nemazinga e testosterone akaderera, zvichienzaniswa ne13% chete yevarume vasina chirwere cheshuga.

Ungaziva sei kuti une testosterone yakaderera mumuviri wako?

Kana uine zviratidzo zve testosterone yakaderera, chiremba achakubvunzurudza muviri. Vachakubvunzawo mibvunzo nezvenhoroondo yako yezvekurapa, mishonga yaunotora kana yawakatora, kana uchisvuta, uye chero zviratidzo zvauri kuona. Vachakuraira kuongororwa kweropa kakawanda.

Kuti aongorore chirwere chako, chiremba achaongorora zviratidzo zvako uye zvabuda muropa rako.

Ndedzipi mhando dzebvunzo dzinoitwa?

Miedzo iyi inogona kubatsira kusimbisa testosterone yakaderera uye kuwana chikonzero:

• Kuongororwa kweropa kwe testosterone yese: Izvi zvinowanzoda kuti utore sampuro mbiri dzeropa pakati pa8 na10 mangwanani, sezvo ndipo panonyanya kukwira testosterone. Unofanira kuudza chiremba wako kana wakamborwara kana kuti wakapora kubva kuchirwere. Kana pakaitika emergency, mhedzisiro yacho inogona kunge yakaderera.
• Kuongororwa ropa kwehomoni yeLuteinizing (LH): Izvi zvinobatsira kuona kana dambudziko negland repituitary riri iro rinokonzera kuderera kwe testosterone.
• Kuongororwa kweropa reprolactin: Kuwanda kweprolactin kunogona kuva chiratidzo chedambudziko repituitary gland kana bundu.

Chii chinoitwa kana testosterone yakaderera?

Vanachiremba vanorapa testosterone yakaderera neTestosterone Replacement Therapy (TRT) . Pane nzira dzakawanda dzekuita izvi:

• Jeri reTestosterone (rinoiswa paganda): Jeri iri rinofanira kushandiswa zuva nezuva paganda rakachena uye rakaoma sezvakarairwa nachiremba wako. Chinonyanya kukosha ndechekuti usarega jeri richisangana nemumwe munhu kuburikidza neganda. Iyi ndiyo nzira inonyanya kushandiswa muUnited States.
• Majekiseni e testosterone mutsinga: Iwe kana chiremba munogona kukupa jekiseni iri mutsandanyama vhiki rega rega 1-2. Kunewo majekiseni e testosterone anoshanda kwenguva refu anopiwa mavhiki gumi ega ega. Kunewo majekiseni emukati memuviri anopiwa pasi peganda.
• Chigamba cheTestosterone (ganda): Chigamba ichi chinofanira kuiswa paganda zuva nezuva sezvakarairwa nachiremba wako. Nzvimbo yekushandiswa inofanira kutenderedzwa nguva nenguva kudzivirira kusawirirana kweganda.
• Mapiritsi eTestosterone (pasi peganda): Nyanzvi ichaisa mapurasitiki aya pasi peganda kwemwedzi mitatu kusvika mitanhatu. Aya anopa testosterone inokura kwenguva yakareba.
• Mapiritsi eBuccal testosterone: Aya mapiritsi anonamira anoiswa pamatadza kaviri pazuva. Testosterone inokurumidza kupinda muropa kuburikidza nematadza.
• Jeri remumhino reTestosterone: Jeri iri rinofanira kuiswa pamhino dzese katatu pazuva.
• Testosterone yemuromo: Rudzi rwe testosterone runonzi undecanoate runopihwa kuvarume vane testosterone shoma nekuda kwemamwe mamiriro ehutano, akadai seKlinefelter syndrome, kana bundu rakakuvadza pituitary gland.

Zvisinei, ungasakwanisa kugamuchira testosterone replacement therapy kana uine nhoroondo yechimwe chezvirwere zvinotevera:

• Kenza yeprostate.
• Bundu reprostate risina kuongororwa. (Munhu wese anofanira kuongororwa prostate yake asati atanga kurapwa ne testosterone.)
• Kenza yemazamu.
• Kukundikana kwemoyo kusingadzoreki.
• Kusarapwa kwechirwere che obstructive sleep apnea.

Ndezvipi migumisiro yekurapa kwekutsiva testosterone?

Zvinotevera zvinogona kuitika semhedzisiro yekurapa uku:

• Ganda rinowanzova nemapundu kana mafuta.
• Kuzvimba kwetsoka nekuda kwekuungana kwemvura mumuviri.
• Zviratidzo zvakaita sekuomerwa nekuita weti nekuda kwekukurudzirwa kweprostate.
• Kukura kwemazamu kana kurwadziwa.
• Kuwedzera kwekushaya hope.
• Matumbu madiki.
• Kana ukashandisa testosterone yakaiswa paganda, unogona kunzwa kuvaviwa uye kuzvimba kweganda.

Shanduko dzinogona kuonekwa mumishumo yerabhoritari:

• Kuwedzera kweprostate-specific antigen (PSA).
• Kuwedzera kwehuwandu hwemasero matsvuku eropa.
• Kuwanda kwembeu dzemurume kwakaderera, zvichikonzera kusabereka (kusakwanisa kuva nevana). Izvi zvakakosha zvikuru kuvarume vechidiki vari kuedza kuva nevana.

Kudzikira kwe testosterone kunogona kudzivirirwa here?

Vanachiremba nevaongorori havasati vaziva nzira yekudzivirira kudzikira kwe testosterone, kungave kuri nekuda kwezvikonzero zvemajini kana kukuvara kwematende, hypothalamus, kana pituitary gland.

Zvisinei, maitiro aya emararamiro anogona kubatsira kuchengetedza mazinga e testosterone akajairwa:

• Kudya chikafu chine hutano.
• Kurovedza muviri.
• Kudzora huremu.
• Dzivisa kushandisa doro zvakanyanya uye zvinodhaka.

Chii chinoitika kana uine testosterone shoma? Chii chaungatarisira?

Hapana mhinduro imwe chete inokodzera zvese yekuderedza testosterone. Zvisinei, nekurapwa kwakakodzera uye kwakakodzera kwemahormone, unogona kuvandudza chido chako chebonde, kuderedza zviratidzo zvekuora mwoyo, uye kuwedzera simba rako. Kurapa kunogonawo kuwedzera tsandanyama uye kuwanda kwemapfupa.

Varume vane testosterone shoma vane huwandu hwakanyanya hwekufa kupfuura varume vane testosterone yakajairika. Zvisinei, hazvizivikanwe kana kudzoreredza testosterone kusvika pahuwandu hwakajairika kuchaderedza huwandu uhwu hwekufa. Kurapa kunonyanya kutarisisa kugadzirisa zviratidzo, kwete kutarisa huwandu hwe testosterone.

Kana munhu aberekwa aine hypogonadism, kurapwa kwekutsiva testosterone kunowanzobatsira kudzivirira matambudziko ane chekuita nekunonoka kuyaruka.

Unofanira kuona chiremba rini nezve testosterone yakaderera?

Kana uri kutora mushonga wekutsiva mahormone, zvakakosha kuti ugare uchiongororwa nachiremba wako.

Kana uine zviratidzo zve testosterone yakaderera, zvakaita sekudzikira kwechido chebonde kana kupisa muviri, taura nachiremba. Iye achakuongorora uye achakuraira kuongororwa kweropa.

Kana mwana wako asati ava kuratidza zviratidzo zvekuyaruka pazera remakore gumi nemana, taura nachiremba wevana vake.

Vanhu vazhinji havaoni zviratidzo zve testosterone shoma sechinhu chinowanzoitika kana munhu akwegura. Zvisinei, kana uine zviratidzo zviri kukanganisa hupenyu hwako, zvakakosha kuti uzviteerere. Kana uri kusangana nezviratidzo zvinonetsa zve testosterone shoma, enda kuna chiremba kuti mukurukure nzira dzekurapa nadzo.

Chinhu chakakosha kurangarira kubva muchinyorwa chino (Mharidzo Yekuenda Kumba)

Kuderera kwe testosterone chirwere chinogona kukanganisa varume. Chinogona kukonzera matambudziko akasiyana-siyana emuviri nepfungwa. Chinhu chakanakisa chekuita ndechekusatya kana kunyara nazvo, asi kutsvaga mazano echiremba. Kana uine zviratidzo, usazvitore sekuti kukwegura kwakajairika.

Kana ukanyatsoongororwa chirwere chako uye ukachirapwa zvakakodzera, unogona kurarama hupenyu hwakanaka. Yeuka kuti hausi wega, uye rubatsiro ruripo.

Testosterone , mahormone evarume, hypogonadism, hutano hwepabonde, kurapwa kwemahormone, hutano hwevarume, kushaya simba