Kana chiremba akakuudza kuti une kenza yemazamu , unofanira kunge wakanzwa kutya kukuru uye kuvhunduka. 'Ndoita sei izvozvi?', 'Ndichapihwa mushonga werudzii?', 'Ndichapihwa chemotherapy here?' Mibvunzo yakawanda inofanira kunge yakauya mupfungwa. Tinoziva kuti kurwisa kenza hakusi nyore. Asi sainzi yekurapa yanhasi yafambira mberi zvakanyanya. Panguva yakaita seiyi, nhasi tiri kutaura nezvebvunzo yakakosha inobatsira vanachiremba kusarudza kuti vangakupa mushonga upi chaizvo.
Chii chinonzi Oncotype DX?
Muchidimbu, Oncotype DX iongororo yakakosha inotarisa zvakadzama masero ekenza yemazamu ako. Haisi bvunzo yeropa yenguva dzose. Inoshandisa chidimbu chenyama yekenza yakatorwa kubva mu biopsy kusimbisa kenza yako kana kubva pakuvhiyiwa kubvisa bundu.
Kuongororwa uku kunotarisa mashandiro emajini mamwe ari mukati memasero ekenza. Kungofanana nemasero edu ese, masero ekenza anewo majini. Majini aya anoona maitiro ekenza, kureva kuti, yakakura sei, kuti inogona kupararira nekukurumidza sei, uye kuti inogona kudzoka sei mushure mekurapwa.
Bvunzo yeOncotype DX inotarisa pamajini makumi maviri nerimwe, ndosaka unganzwa ichinzi bvunzo ye "21-gene signature". Nekuongorora mapatani emajini aya, vanachiremba vanogona kudzidza ruzivo rwakakosha nezvegomarara rako.
Ndiani anokurudzirwa kuita bvunzo iyi?
Kuongororwa uku hakudiwi kune varwere vese vane kenza yemazamu. Chiremba wako anogona kukurudzira kuongororwa uku kana uine chimwe chezvirwere zvinotevera:
- Kana uine kenza iri padanho rekutanga (Danho rekutanga kana rechipiri): Izvi zvinoreva kuti kenza haisati yapararira kune dzimwe nzvimbo dziri kure dzemuviri.
- Kana kenza iri estrogen-receptor positive (ER+): Izvi zvinoreva kuti masero ekenza anokura nekuda kwehomoni inonzi estrogen inogadzirwa nemuviri wako. Rudzi urwu rwekenza runowanzo shandiswa kurapwa nehomoni .
- Kana kenza isati yapararira kusvika kuma lymph nodes ari mugumbo.
Pamusoro pezvo, bvunzo iyi dzimwe nguva inogona kuitwa kune vanhu vane nhanho dzekutanga dzekenza inonzi DCIS (Ductal Carcinoma in Situ) , kuti vabatsire kusarudza kana kurapwa nemwaranzi kuchidikanwa.
Chinhu chinonyanya kukosha ndechekuti rubatsiro rukuru kubva mubvunzo iyi nderekuti unowana gwara rekusarudza kana uchida kurapwa nechemotherapy pamwe nekurapwa nehomoni.
Unoverenga sei mamakisi ebvunzo?
Kuongororwa kweOncotype DX kunokupa "Recurrence Score" pakati pe0 ne100. Kana mamakisi aya akakwira, njodzi yekuti kenza ichadzoka mushure mekurapwa inowedzera. Zvisinei, maverengerwo emakisi aya achasiyana zvishoma zvichienderana nezera rako.
| Range yeZvibodzwa | Njodzi | Zvinogona Kukurudzirwa |
|---|---|---|
| 0 – 25 | Njodzi shoma | Kurapwa nemahormone chete kunogona kukwana. Pane mukana mudiki wekuti mishonga yechemotherapy ibatsire zvakanyanya. |
| 26 - 100 | Njodzi yakakura | Njodzi yekuti kenza idzoke yakakwira. Kurapa nemakemikari kunogona kukurudzirwa pamwe chete nekurapwa nehomoni. |
| Range yeZvibodzwa | Njodzi | Zvinogona Kukurudzirwa |
|---|---|---|
| 0 – 15 | Njodzi shoma | Kurapa nemahormone chete kunogona kukwana. Pane mukana mudiki wekuti mishonga yekurapa ibatsire zvakanyanya. |
| 16 - 20 | Njodzi iri pakati nepakati | Kurapa nemakemikari kunogona kupa purofiti diki, asi unofanira kukurukura nachiremba wako kana purofiti yacho ichikosha kana tichienzanisa nemigumisiro yacho. |
| 21 - 25 | Njodzi iri pakati nepakati | Mabhenefiti ekurapa chemotherapy anogona kupfuura njodzi dzemigumisiro yayo. Unofanira kukurukura izvi nachiremba wako woita sarudzo. |
| 26 - 100 | Njodzi yakakura | Njodzi yekuti kenza idzoke yakakwira. Kurapa nemakemikari (chemotherapy) kunokurudzirwa pamwe chete nekurapwa nehomoni. |
Chiratidzo ichi chega ndicho chinofanira kusarudza kurapwa here?
Kwete zvachose. Izvi zvakakosha zvikuru. Oncotype DX score chinhu chimwe chete chakasimba chinokubatsira kuita sarudzo. Chiremba wako achafunga nezvezvimwe zvinhu zvakawanda asati agadzira chirongwa chakanakisa chekurapa.
Semuyenzaniso:
- Kukura kwebundu
- Giredhi rebundu
- Huwandu hwemahormone receptors mumasero ekenza
- Zera rako nehutano hwako hwese
Zvinhu zvese izvi zvinosangana kuti pave nesarudzo yekupedzisira. Saka, mushumo uyu webvunzo ingori imwe chete nzira inogona kubatsira chiremba wako kugadzira hurongwa hwakanakisa hwekurapa iwe.
Pane mimwe miedzo yemajini yakaita seiyi here?
Ehe, kune mimwe miedzo yakawanda yejini inoshandiswa pakurapa kenza yemazamu. Asi inonyanya kushandiswa ichiri Oncotype DX. Ngatidzidzei muchidimbu nezvemimwe yacho.
- MammaPrint: Iyi inoedza majini makumi manomwe. Inobatsira kufanotaura njodzi yekupararira kwegomarara kunze kwezamu. Inogona kushandiswa kune ese ari maviri ER+ uye ER- types.
- Mammostrat: Iyi inoedza majini mashanu uye inoyera njodzi yekuti kenza yemazamu ine mahormone-receptors isati yatanga yadzoka.
- Prosigna: Iyi inoshandiswa pakurapa kenza yemazamu ine mahormone-receptors mumadzimai apedza kuenda kumwedzi. Inoongorora majini makumi mashanu nemasere uye inofanotaura njodzi yekuti kenza idzoke kune imwe nzvimbo mumuviri mukati memakore gumi.
Zvese izvi bvunzo dzepamusoro. Chiremba wako ndiye achasarudza kana uchida imwe yeidzi uye kuti ndeipi yakakodzera.
Mharidzo Yekuenda Nayo Kumba
- Oncotype DX inzira yakakosha yekuongorora majini emasero ekenza yemazamu kuti ibatsire kuona njodzi yekudzoka kwekenza uye kana chemotherapy ichidikanwa.
- Izvi zvinoitwa nechidimbu chenyama yekenza inotorwa kubva pakuongororwa kweropa kana kuvhiyiwa, kwete kubva muropa.
- Bvunzo iyi haidiwi nemunhu wese. Inonyanya kushandiswa kune kenza dziri padanho rekutanga/rechipiri, ER+, uye dzisina kupararira kuma lymph nodes.
- Chiyero chebvunzo chikamu chimwe chete chechirongwa chekurapa. Chiremba wako achafunga nezvezvimwe zvinhu zvakawanda, zvakaita sehukuru hwegomarara, kuoma kwaro, uye zera rako.
- Kana muine mibvunzo kana zvinokunetsai nezvazvo, iva nechokwadi chekutaura pachena nachiremba wenyu . Iye achakubatsirai kusarudza zvakakunakirai.
Oncotype DX Sinhala, Kenza yeZamu, Kurapa neKemikari, Kuongororwa kwemajini eKenza, Kudzokorora Kenza, Kenza Yakanaka yeER , Kurapwa kweKenza
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