Mwana wako mudiki anongogara achirwara nefivha here? Anova nani here mushure mefivha kwemazuva mashoma, ozowanazve fivha mushure memazuva mashoma? Ungave uchishamisika kuti sei izvi zvichiitika pasina hutachiona kana hutachiona hwebhakitiriya. Izvi zvinogona kunge zvichikonzerwa nechirwere chisingawanzoitiki chinonzi SAIDs (Systemic Autoinflammatory Diseases) , icho vanhu vazhinji vasati vanzwa nezvacho. Musazvidya mwoyo, ngatitaurei nezvazvo nemashoko akareruka uye tinzwisise zvese.
Chii chinonzi SAIDs? Ngatizvinzwisise zviri nyore.
Zvichitaurwa zviri nyore, maSAID iboka rezvirwere zvinokonzera fivha dzinogara dzichiitika pasina hutachiona (senge mavhairasi kana mabhakitiriya). Chikonzero cheizvi idambudziko remuviri wemwana wedu. Izvi zvaimbonzi 'Periodic Fever Syndromes'.
Zvino ungave uchishamisika kuti, ichi chirwere che 'autoimmune' here? Tinowanzonzwa nezvezvirwere zve autoimmune zvakaita seRheumatoid Arthritis kana Lupus. Kwete, izvi zvakasiyana.
Fungidzira kuti tine uto rekudzivirira mukati memuviri wedu, iro immune system yedu. Uto iri rine zvikamu zviviri zvikuru:
1. Sisitimu Yemuviri Yekudzivirira Kurwara: Iri ndiro uto ratakaberekwa naro, uye ndiro rekutanga kurwisa chero utachiona.
2. Sisitimu yekudzivirira muviri inochinjika: Iri iuto rakadzidziswa kurwisa utachiona hwakasiyana-siyana sezvatinokura.
MuSAIDs, dambudziko riri paimmune system yatinozvarwa nayo. Iyo immune system inokanganiswa uye inotanga kurwa mumuviri pasina muvengi. Mugumisiro wekurwa uku kuzvimba mumuviri nefivha.
Asi muzvirwere zve autoimmune zvatakataura nezvazvo, dambudziko riri pauto rinochinjika rinozodzidziswa gare gare. Hondo iyoyo haikwanise kuziva masero akanaka mumuviri wayo uye inotanga kuarwisa.
MaSAID haawanzoitiki kupfuura zvirwere zve autoimmune. Anowanzo kukonzerwa nezvikonzero zvemajini , zvichireva kuti anogarwa nhaka. Zviratidzo izvi zvinowanzotanga mwana achiri mudiki, senge panguva yehucheche kana mwana mudiki. Mwana anoerekana arwara nefivha nezvimwe zviratidzo, izvo zvinowanzopera mukati memazuva mashoma. Mwana anogona kunge akasimba zvakakwana kana asina kurwara. Kunyangwe pasina mushonga, kune mishonga inoshanda inogona kudzora zviratidzo.
Ndeapi marudzi makuru eSAIDs?
Vaongorori vakaona mhando dzeSAID dzinosvika makumi matanhatu kusvika pari zvino, uye mhando itsva dziri kuwanikwa nguva dzese. Heano mamwe emhando dzakajairika.
| Zita rechirwere (Rudzi rweSAID) | Sumo pfupi |
|---|---|
| Fivha yeMediterranean yemhuri (FMF) | Iyi ndiyo mhando yeSAID inozivikanwa nemajini, inokonzera kuzvimba kunorwadza mudumbu, pachipfuva, uye pamapfundo. |
| Fivha yenguva nenguva, Aphthous-Stomatitis, Pharyngitis, Adenitis (PFAPA) | Zvinotanga kuvana vadiki, kunyanya vasati vasvitsa makore mana. Zviratidzo zvakaita sekurwadziwa pahuro, maronda emuromo, uye kuzvimba kwemutsipa zvinouya nefivha. Zvinowanzopera mushure memakore gumi. |
| Chirwere chePeriodic Syndrome cheTumor Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS) | Izvi zvinogona kutanga paudiki kana kunyange kuyaruka. |
| Kushaikwa kweMevalonate Kinase (MKD) | Izvi zvinowanzotanga mwana asati asvitsa gore rimwe chete. |
| Zvirwere zveNLRP3-Zvinobatanidzwa neAutoinflammatory (CAPS) | Izvi chaizvoizvo musanganiswa wezvirwere zvitatu zvakasiyana. |
| Chirwere chevanhu vakuru-chekutanga (AOSD) | Sezvinotaurwa nezita racho, ichi chirwere chinotanga munhu akura. |
| Chirwere cheBlau | Izvi zvinowanzoitika kuvana vari pasi pemakore mana. Zvinonyanya kukanganisa ganda, maziso, uye majoini. |
Ndezvipi zviratidzo zvinowanzoonekwa zvezvirwere izvi?
Chiratidzo chikuru uye chinowanzoonekwa cheSAIDs ifivha inodzokororwa . Zvisinei, pamusoro pefivha, zvimwe zviratidzo zvinogonawo kuitika zvichienderana nerudzi rwechirwere.
Chinhu chakakosha ndechekuti zviratidzo izvi zvinongoitika panguva yekurwara chete. Kana nguva iyoyo yapera, mwana anogona kuva neutano hwakanaka asina zviratidzo.
| Zita rechirwere (Rudzi rweSAID) | Zviratidzo zvekutarisa |
|---|---|
| FMF | Kurwadziwa kwakanyanya mudumbu, pachipfuva, uye pamapfundo. Maronda eganda pamakumbo epasi kana muzviziso. |
| PFAPA | Huro inorwadza, maronda emuromo, kuzvimba kwema lymph nodes mumutsipa. |
| MITSUNGO | Muviri unonzwa kutonhora uye kudedera. Kune kurwadziwa mutsandanyama dzemuviri, kunyanya muhudyu nemumaoko. Mavara matsvuku anorwadza anogona kuoneka mumuviri wese. |
| MKD | Muviri unonzwa kutonhora uye kudedera, uchirwadziwa nemusoro, kurwadziwa mudumbu, kushaya chido chekudya, uye zviratidzo zvakafanana nezvechikosoro. |
| Zvirwere zveNLRP3 | Mapundu eganda, musoro, kuneta, kurwadziwa kwemajoini, uye hutachiona hwemaziso (conjunctivitis). |
| Chirwere cheBlau | Maronda eganda pamaoko, makumbo, kana hunde yemwana. Marwadzo emajoini nekurwadziwa kwemaziso. |
Sei zvirwere izvi zvichiitika? Ndezvipi zvinokonzera?
Sezvatakambotaura, maSAID mazhinji zvirwere zvemajini . Izvi zvinoreva kuti zvirwere izvi zvinokonzerwa nekuchinja kwejini (variant) mune rimwe jini.
| Zita rechirwere (Rudzi rweSAID) | Gene Rinobatanidzwa |
|---|---|
| FMF | Jini reMEFV |
| PFAPA | Chikonzero chaicho hachisati chawanikwa. |
| MITSUNGO | Jini reTNFRSF1A |
| MKD | Jini reMVK |
| Zvirwere zveNLRP3 | Jini reNLRP3 |
| AOSD | Chikonzero chaicho hachisati chawanikwa. |
| Chirwere cheBlau | Jini reNOD2 |
Chii chingaitika kana kurapwa kwakakodzera kukasaitwa?
Iyi inyaya yakakosha zvikuru. Zvakakosha kudzora chirwere ichi nekutora kurapwa kwakakodzera. Nekuti, kana paine kuzvimba kunoramba kuripo mumuviri seizvi, zvinogona kutungamira kuchirwere chinonzi Amyloidosis . Zvichitaurwa zviri nyore, rudzi rweprotein runogona kuiswa muitsvo dzedu, zvichikonzera kukuvara kusingaperi kweitsvo. Saka, zvakakosha zvikuru kuongorora chirwere ichi uye kuchirapa nekukurumidza.
Chiremba anoongorora sei chirwere ichi?
Kutaura chokwadi, kuongorora SAIDs kunogona kuoma nekuti zviratidzo zvinogona kufanana nezvezvimwe zvirwere zvakakomba, zvakaita se lupus.
Saka, chinhu chakakosha ndechekuona chiremba ane ruzivo nezvezvirwere zverudzi urwu. Chiremba ane ruzivo nezvezvirwere zvine chekuita nemajoini nemasoja emuviri anonzi Rheumatologist .
Chiremba wako achafunga nezvezvinhu zvakati wandei kuti aongorore chirwere chacho. Angangobvunza nezvezviratidzo zvemwana wako uye kana paine nhoroondo yemhuri yechirwere ichi. Chiremba wako angangofungidzira kuti ane SAIDs, kunyanya kana:
- Kana mwana achigara achirwara nefivha.
- Kana paine mumwe munhu mumhuri akamborwara nezvirwere zvakaita sefuruu zvakare.
- Sezvo zvirwere izvi zvakajairika pakati pemamwe mapoka emadzinza, izvozvo zviri kufungwawo nezvazvo.
Miedzo ipi inoitiswa?
Chiremba anogona kukurudzira bvunzo dzinoverengeka kuti asimbise chirwere chacho.
- Kuongororwa kweropa (Kuongororwa kweLab): Kuongororwa kwakadai seC-reactive protein (CRP) neCBC (Full Blood Count) kunogona kutarisa kuzvimba mumuviri. Mazinga aya anowedzera panguva yekurwara uye anodzokera padanho rakajairika kana muviri wapora.
- Kuongororwa kweweti: Kunoongorora huwandu hwemapuroteni muweti. Mune zvimwe zvirwere, zvakaita seMKD, kuongororwa kweweti kunogona kuona maasidhi chaiwo.
- Kuongororwa kwemajini: Kuongororwa uku kunogona kuona shanduko dzemajini. Zvisinei, dzimwe nguva, mwana anogona kunge aine SAID asi bvunzo yemajini ingasaione. Saka, kunyangwe mhinduro yeongororo iri isina kunaka, hazvigone kutaurwa 100% kuti chirwere hachipo.
Ndezvipi zvinorapwa izvi?
Kurapwa kweSAIDs kunoenderana nerudzi uye kuoma kwechirwere. Kunyangwe zvirwere izvi zvisingarapike zvachose, mishonga inogona kudzora zviratidzo zvakanyanya.
- FMF: Mushonga unonzi Colchicine unoshandiswa pakuita izvi. Unoderedza kuzvimba mumuviri. Kana mushonga iwoyo usingashande kumwana, anogona kushandisa mishonga yakaita seCanakinumab .
- PFAPA: Mishonga yeSteroid yakaita sePrednisone inogona kupiwa kwenguva pfupi kuti ideredze nguva yechirwere nekukurumidza.
- MISUNGO: CanakinumabMushonga uyu unoshanda zvikuru. Uyewo, mishonga inorwisa kuzvimba yakaita seglucocorticoids inoshandiswa.
- MKD: Mushonga weCanakinumab unoshandawo pakuita izvi. Panguva yekurwara, mishonga yeNSAIDs (mishonga inouraya marwadzo) kana steroid inogona kubatsira.
- Zvirwere zveNLRP3: Mishonga inochinja dziviriro yemuviri yakaita seCanakinumab , Rilonacept , uye Anakinra inoshandiswa zvinobudirira pakuita izvi.
- Blau Syndrome: Zvichienderana nezviratidzo, mishonga inodzvinyirira immune system, TNF inhibitors, uye mishonga yemaziso inogona kushandiswa.
Ko chirwere ichi chicharapwa zvachose here?
Mamwe maSAIDs ndeehupenyu hwese. Zvisinei, mamwe, sePFAPA, anogona kupera ega mwana paanokura. Kunyangwe ari mamiriro ehupenyu hwese, kuwanda kwekurwara uye kuoma kwezviratidzo zvinogona kudzikira nekufamba kwenguva. Chiremba wako achakupa ruzivo rwakananga nezvemamiriro emwana wako.
Kuchengeta mwana ane chirwere ichi kunogona kuoma. Asi nerubatsiro rwenyanzvi dzakakodzera, unogona kugadzirisa zviratidzo zvemwana wako uye kumupa hudiki hwakanakisisa.
Mharidzo Yekuenda Nayo Kumba
- Kana mwana wako achigara achirwara nefivha pasina chikonzero chakajeka, usangomusiya wobva waona chiremba nekukasika.
- SAIDs iboka rezvirwere zvisingawanzoitiki zvinokonzerwa nedambudziko riri muchikamu chemuviri chemuviri chekudzivirira muviri.
- Izvi hazvisi zvirwere zvinotapuriranwa; zvinowanzokonzerwa nezvinhu zvinokonzerwa nemajini.
- Zvakakosha zvikuru kuona chiremba wemapfupa (chiremba anonyanya kugadzira majoini nemasoja emuviri) kuti aongorore chirwere chacho nemazvo.
- Kunyange zvazvo izvi zvisingarapike zvachose, mishonga inogona kubatsira kudzora zviratidzo uye kukubvumira kurarama hupenyu hwakajairika.
💬 Comments (0)
Hapana zvakataurwa parizvino. Isa mhinduro yako pano kekutanga.
Wedzera zvaunofunga